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Turkderm-Archives of the Turkish Dermatology and Venerology最新文献

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Topical therapies 局部治疗
Q4 Medicine Pub Date : 2022-05-05 DOI: 10.4274/turkderm.galenos.2022.68638
S. Yaylı
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引用次数: 0
Combination therapies in psoriasis 银屑病的联合治疗
Q4 Medicine Pub Date : 2022-05-05 DOI: 10.4274/turkderm.galenos.2022.77675
E. Koc, E. Bülbül Başkan
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引用次数: 0
Use of biological agents 使用生物制剂
Q4 Medicine Pub Date : 2022-05-05 DOI: 10.4274/turkderm.galenos.2022.81594
S. Alper, E. Koc
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引用次数: 0
Cyclosporine 环孢霉素
Q4 Medicine Pub Date : 2022-05-05 DOI: 10.1007/springerreference_38104
Nahide Onsun
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引用次数: 0
Biosimilars 生物类似物
Q4 Medicine Pub Date : 2022-05-05 DOI: 10.4274/turkderm.galenos.2022.06978
E. Bülbül Başkan
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引用次数: 0
Dupilumab for atopic dermatitis treatment: A single-center retrospective study Dupilumab治疗特应性皮炎的单中心回顾性研究
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.4274/turkderm.galenos.2021.36604
Gülbin Yaşar, A. Bilgic, E. Yılmaz
Background and Design: Atopic dermatitis (AD) is a common chronic, recurrent, and itchy inflammatory skin disease. Various therapeutic agents are available, but severe side effects may limit their usage. Recently, dupilumab, a human monoclonal antibody that targets the interleukin-4 (IL-4) receptor alpha subunit of heterodimeric IL-4 and IL-13 receptors, is approved and might be used in patients with resistant AD, with the permission of the Ministry of Health. Materials and Methods: This study aimed to retrospectively evaluate the clinical characteristics of patients and dupilumab treatment responses in our center. This study included patients with AD who were unresponsive to conventional treatments and treated with dupilumab. Sociodemographic, laboratory data, previous treatments, and responses along with disease severity scores [eczema area and severity index (EASI)] before and after dupilumab were evaluated through the electronic files of patients. Results: A total of 21 patients (13 males and 8 females) between June 2019 and March 2021 were identified. The mean age of patients was 40.57±15.21 years. The mean duration of dupilumab treatment was 6.59±5.88 months. The mean EASI score at the beginning of dupilumab was 15.35±8.03, whereas 4.6±2.9 after treatment. A 70-100% improvement was found in approximately 75% of the patients. No side effects were observed that required treatment discontinuation or dose changes. Conclusion: Our study has the highest number of reported patients in our country, which revealed that dupilumab is highly effective and safe for conventional treatment-resistant AD.
背景与设计:特应性皮炎(AD)是一种常见的慢性、复发、瘙痒的炎症性皮肤病。有各种治疗剂,但严重的副作用可能会限制它们的使用。最近,一种靶向异二聚体IL-4和IL-13受体的白细胞介素-4(IL-4)受体α亚基的人类单克隆抗体dupilumab获得批准,并可能在获得卫生部许可的情况下用于耐药性AD患者。材料和方法:本研究旨在回顾性评估我们中心患者的临床特征和dupilumab治疗反应。这项研究包括对常规治疗无反应并接受杜匹单抗治疗的AD患者。通过患者的电子文件评估dupilumab前后的社会记录、实验室数据、既往治疗、反应以及疾病严重程度评分[湿疹面积和严重程度指数(EASI)]。结果:在2019年6月至2021年3月期间,共确认了21名患者(13名男性和8名女性)。患者平均年龄为40.57±15.21岁。dupilumab治疗的平均持续时间为6.59±5.88个月。dupilumab治疗开始时的平均EASI评分为15.35±8.03,而治疗后为4.6±2.9。在大约75%的患者中发现了70-100%的改善。未观察到需要停药或改变剂量的副作用。结论:我们的研究报告的患者数量在我国最高,这表明杜匹单抗对常规治疗耐药的AD是高效和安全的。
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引用次数: 0
Pityriasis rubra pilaris developing after COVID-19 COVID-19后发生的毛状红斑糠疹
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.4274/turkderm.galenos.2021.26235
M. Kuş, Perihan Öztürk, H. Nazik, M. Mülayim, Tutku Bulut, Esra Rabia Akgüç, S. Koçarslan
Coronavirus disease-2019 (COVID-19) has been associated with multiple skin lesions as well as causing common respiratory symptoms. We presented a case of pityriasis rubra pilaris that developed after COVID-19 infection and treated with anti-tumor necrosis factor (adalimumab), which was not previously reported in an adult.
冠状病毒病-2019 (COVID-19)与多种皮肤病变以及引起常见的呼吸道症状有关。我们报告了一例在COVID-19感染后发生并使用抗肿瘤坏死因子(阿达木单抗)治疗的红色毛糙糠疹,该病例以前未在成人中报道。
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引用次数: 0
Correlation between serum uric acid, C-reactive protein, and neutrophil-to-lymphocyte ratio in patients with psoriasis: A case-control study 银屑病患者血清尿酸、c反应蛋白和中性粒细胞与淋巴细胞比值的相关性:一项病例对照研究
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.4274/turkderm.galenos.2021.69797
S. Mishra, Manjunath Kadnur, Shishira R. Jartarkar, Hanumanthayya Keloji, Ritu Agarwa, Spoorthy Babu
Vaccicare Clinic, Department of Dermatology, Cuttack, India *Vydehi Institute of Medical Sciences and Research Center, Department of Dermatology, Venereology and Leprosy, Bangalore, India **Sri Devaraj Urs Medical College, Department of Dermatology, Venereology and Leprosy, Kolar, India ***Kaya Skin Clinic, Department of Dermatology, Mumbai, India Swayamsidda Mishra, Manjunath Kadnur*, Shishira R. Jartarkar*, Hanumanthayya Keloji**, Ritu Agarwal***, Spoorthy Babu*
印度卡塔克Vaccicare诊所皮肤病科*维德希医学科学研究所和研究中心皮肤病、性病和麻风病科**印度科拉斯Sri Devaraj Urs医学院皮肤病、性病和麻风病科**印度孟买卡亚皮肤诊所皮肤病科Swayamsidda Mishra Manjunath Kadnur* Shishira R. Jartarkar* Hanumanthayya Keloji** Ritu Agarwal** sporthy Babu*
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引用次数: 1
Facial hypertrichosis after isotretinoin therapy: Is it a side effect or coincidence? 异维甲酸治疗后面部多毛:是副作用还是巧合?
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.4274/turkderm.galenos.2021.32396
Esra Saraç, A. Ünal
©Copyright 2022 by Turkish Society of Dermatology and Venereology Turkderm-Turkish Archives of Dermatology and Venereology published by Galenos Yayınevi. Cite this article as: Saraç E, Ünal A. Facial hypertrichosis after isotretinoin therapy: Is it a side effect or coincidence?.Turkderm-Turk Arch Dermatol Venereol 2022;56:7-11 Ori gi nal In ves ti ga ti on Ori ji nal Arafl t›r ma Saraç and Ünal. Facial hypertrichosis after isotretinoin therapy
©版权所有2022由土耳其皮肤病和性病学会turkderm -土耳其皮肤病和性病档案由Galenos出版Yayınevi。引用这篇文章:Saraç E, Ünal a .异维甲酸治疗后面部多毛:是副作用还是巧合?Turkderm-Turk Arch Dermatol Venereol 2022;56:7-11 Ori gi signal In ves . i ' ve . i ' rma Saraç and Ünal。异维甲酸治疗后面部多毛
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引用次数: 0
The effects of isotretinoin on the inner ear in patients with acne vulgaris 异维甲酸对寻常痤疮患者内耳的影响
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.4274/turkderm.galenos.2021.73659
Esra İnan Doğan, Özlem Yağız Aghayarov
Address for Correspondence/Yazışma Adresi: Esra İnan Doğan MD, Adıyaman University Faculty of Medicine, Department of Dermatology, Adıyaman, Turkey Phone: +90 553 852 94 20 E-mail: esranander@yahoo.com Received/Geliş Tarihi: 06.09.2021 Accepted/Kabul Tarihi: 29.11.2021 ORCID: orcid.org/0000-0002-9539-334X Cite this article as: İnan Doğan E, Yağız Aghayarov Ö. The effects of isotretinoin on the inner ear in patients with acne vulgaris. Turkderm-Turk Arch Dermatol Venereol 2022;56:17-23 Abstract
通讯地址/Yazışma Adresi:Esraïnan Doğan医学博士,阿季亚曼大学医学院皮肤科,阿季亚曼,土耳其电话:+90 553 852 94 20电子邮件:esranander@yahoo.com收到/GelişTarihi:2021年9月6日接受/Kabul Tarihi:2021年11月29日ORCID:ORCID.org/0000-0002-9539-334X引用本文为:伊南·多安E,Yağız AghayarovÖ。异维甲酸对寻常痤疮患者内耳的影响。Turkderm Turk Arch Dermatol Venereol 2022;56:17-23摘要
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引用次数: 0
期刊
Turkderm-Archives of the Turkish Dermatology and Venerology
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