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Bilateral ovarian vein coil embolization with crossover technique in pelvic venous disease: One year follow-up results. 交叉技术双侧卵巢静脉线圈栓塞治疗盆腔静脉疾病:一年随访结果。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27100
Serkan Ketenciler, Mehmet Ali Yeşiltaş, Ahmet Ozan Koyuncu, Özgür Gursu, İlhan Sanisoğlu

Background: In this study, we aimed to evaluate one-year clinical follow-up of patients who underwent bilateral ovarian vein embolization using crossover maneuvers between the ovarian veins via unilateral puncture.

Methods: Between January 2017 and September 2022, a total of 34 women (mean age: 39.6±4.9 years; range, 26 to 52 years) who had pelvic venous disease and underwent bilateral embolization of ovarian veins with unilateral puncture and collateral crossover were retrospectively analyzed. The patients were followed at one, six, and 12 months postoperatively. Symptoms were evaluated using physical examination findings and Visual Analog Scale scores and the need for reintervention was assessed.

Results: Of a total of 34 patients, 21 (61.8%) reported dysmenorrhea and 18 (53%) reported both dyspareunia and lower limb varices. There were no major complications during the procedure. The mean preoperative Visual Analog Scale score was 8.1±0.8, which decreased to 2.1±0.6 at 12 months. Reintervention was necessary for only one patient during one-year follow-up.

Conclusion: Although bilateral ovarian vein embolization with crossover to the contralateral side poses greater technical challenges than unilateral ovarian vein closure, it remains a viable technique with favorable outcomes and lower complication rates.

背景:在这项研究中,我们旨在评估通过单侧穿刺卵巢静脉间交叉操作进行双侧卵巢静脉栓塞的患者一年的临床随访。方法:2017年1月至2022年9月,共34例女性(平均年龄:39.6±4.9岁;回顾性分析了26 ~ 52岁的盆腔静脉疾病患者,并通过单侧穿刺和侧支交叉进行双侧卵巢静脉栓塞。分别于术后1、6、12个月进行随访。使用体格检查结果和视觉模拟量表评分评估症状,并评估再干预的必要性。结果:在34例患者中,21例(61.8%)报告痛经,18例(53%)报告性交困难和下肢静脉曲张。手术过程中没有出现重大并发症。术前平均视觉模拟量表评分为8.1±0.8,12个月时降至2.1±0.6。在一年的随访中,只有1例患者需要再干预。结论:虽然双侧卵巢静脉栓塞术与单侧卵巢静脉栓塞术相比技术挑战更大,但仍是一种可行的技术,效果良好,并发症发生率低。
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引用次数: 0
Evaluation of gender bias in thoracic surgery in Türkiye: A descriptive study. 评估<s:1>基耶省胸外科手术中的性别偏见:一项描述性研究。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27062
Gizem Keçeci Özgür, Ayşe Gül Ergönül, Kevser Durgun, Gamze Tanrıkulu

Background: This study aims to investigate the challenges that female thoracic surgeons in Türkiye faced to due to gender bias in their professional lives.

Methods: Between January 2024 and April 2024, a total of 73 female thoracic surgeons (mean age: 37.1±7.4 years; range, 25 to 53 years) who were working in Türkiye and completed a 44-question survey were included. The online questionnaire was sent by email. It was also shared and disseminated in communication groups (WhatsApp).

Results: Of the 73 participants, 45.2% thought that their academic progress was made more difficult due to being women, 49.3% thought that female surgeons were less likely to have influence in their department, and this perception was more prevalent among specialists than among residents (p=0.029). A total of 64.4% of the participants reported being subjected to mobbing in their professional life due to being women. In addition, 56.2% participants thought that they were taken less seriously by patients, as they were women, and this thought was particularly more prevalent among resident physicians (p=0.038). Totally 75.3% of the participants were subjected to verbal or physical violence by patients or their relatives, and 85% thought that the career of female surgeons would be more affected when they had children compared to male surgeons with children. Also, 42.5% of the participants postponed or would postpone pregnancy to a later time.

Conclusion: Our study highlights the urgent need for change by revealing the challenges faced by female thoracic surgeons in Türkiye, including obstacles in training, professional advancement, and achieving a balance between work, children, and family life, all of which are exacerbated by gender bias.

背景:本研究旨在探讨基耶女胸外科医生在职业生涯中因性别偏见而面临的挑战。方法:2024年1月~ 2024年4月,共73例女性胸外科医生(平均年龄:37.1±7.4岁;年龄从25岁到53岁不等),这些人都在日本工作,并完成了一份包含44个问题的调查。在线问卷是通过电子邮件发送的。它还在通信群(WhatsApp)中被分享和传播。结果:在73名参与者中,45.2%的人认为她们的学业进步因为是女性而变得更加困难,49.3%的人认为女外科医生在她们的科室不太可能有影响力,这种看法在专科医生中比在住院医生中更普遍(p=0.029)。总共有64.4%的参与者报告说,他们在职业生涯中因为是女性而受到围攻。此外,56.2%的参与者认为患者不太重视他们,因为他们是女性,这种想法在住院医师中尤为普遍(p=0.038)。共有75.3%的参与者遭受过患者或其亲属的言语或身体暴力,85%的参与者认为女外科医生有孩子后的职业生涯比有孩子的男外科医生受到的影响更大。此外,42.5%的参与者推迟或将推迟怀孕到更晚的时间。结论:我们的研究揭示了 rkiye女性胸外科医生所面临的挑战,包括在培训、职业发展、实现工作、孩子和家庭生活之间的平衡方面的障碍,这些都因性别偏见而加剧,突显了迫切需要做出改变。
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引用次数: 0
Is it safe to perform coronary artery bypass grafting surgery in patients with hemophilia? A case series of four patients. 血友病患者行冠状动脉搭桥术安全吗?4例患者的病例系列。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.25800
Fatoş Dilan Köseoğlu, Zühal Demirci, Ümit Kahraman, Güray Saydam, Fahri Şahin

Hemophilia is a genetic disorder that mainly affects males and leads to a higher risk of bleeding. There is a lack of clarity regarding the safety of coronary artery bypass grafting (CABG) surgery in patients with hemophilia. In this case series, real-life data of four male hemophilia patients aged 45 to 66 years who underwent CABG was presented. One patient needed to undergo reexploration due to nonsurgical bleeding. However, all patients were discharged in good condition. The current experience revealed that CABG in hemophilia patients is safe to perform with a multidisciplinary approach involving hematologists, anesthesiologists, and cardiovascular surgeons.

血友病是一种遗传性疾病,主要影响男性,导致出血的风险更高。血友病患者冠状动脉旁路移植术(CABG)的安全性尚不明确。在本病例系列中,介绍了4例45 - 66岁男性血友病患者行冠脉搭桥的真实资料。1例患者因非手术性出血需要重新探查。所有患者出院时情况良好。目前的经验表明,血友病患者的冠脉搭桥手术是安全的,多学科方法包括血液学家、麻醉师和心血管外科医生。
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引用次数: 0
Additional insights into the outcomes after combined heart-lung surgery. 对心肺联合手术后结果的进一步了解。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27538
Rohan Magoon
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引用次数: 0
Artificial intelligence to predict biomarkers for new-onset atrial fibrillation after coronary artery bypass grafting. 人工智能预测冠状动脉搭桥术后新发房颤的生物标志物。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27304
Birkan Akbulut, Mustafa Çakır, Mustafa Görkem Sarıkaya, Okan Oral, Mesut Yılmaz, Güzin Aykal

Background: This study aims to identify predictors of postoperative atrial fibrillation in coronary artery bypass grafting patients using routinely collected preoperative tests.

Methods: Between January 2020 and December 2023, a total of 50 patients with postoperative atrial fibrillation (POAF group; 39 males, 11 females; mean age: 65.9±8.3 years; range, 38 to 77 years) and 50 without postoperative atrial fibrillation (non-POAF group; 41 males, 9 females; mean age: 61.8±10.0 years; range, 41 to 81 years) were randomly selected from a group of patients undergoing two or three-vessel coronary artery bypass grafting. We analyzed preoperative laboratory, demographic and intraoperative data using machine learning models.

Results: The overall incidence of postoperative atrial fibrillation was 21.69%. The three most effective biomarkers were magnesium, total iron binding capacity, and albumin, respectively. A total of 2.0 mg/dL value of magnesium was identified as a threshold value. Magnesium values below 2.0 mg/dL were considered atrial fibrillation-positive, accounting for 25% of the dataset. Total iron binding capacity values higher than 442 µg/dL were considered atrial fibrillation-positive, accounting for 12% of the dataset. The threshold value for albumin was 29 g/dL, and patients with values under this value were considered atrial fibrillation-positive, accounting for 4% of the dataset.

Conclusion: Machine learning models demonstrate encouraging results in identifying risk factors for many entities. It is of utmost importance to establish a ranking among risk factors and determine threshold values to support clinicians in decision making. This is our first experience with machine learning in this patient group after cardiac surgery. Further studies are warranted to confirm these data.

背景:本研究旨在通过常规收集的术前检查确定冠状动脉旁路移植术患者术后房颤的预测因素。方法:2020年1月至2023年12月,共50例术后心房颤动患者(POAF组;男性39人,女性11人;平均年龄:65.9±8.3岁;38 ~ 77岁)和术后无房颤的50例(非poaf组;男性41人,女性9人;平均年龄:61.8±10.0岁;年龄在41岁至81岁之间),随机选择接受两支或三支冠状动脉搭桥术的患者。我们使用机器学习模型分析术前实验室、人口统计学和术中数据。结果:术后心房颤动总发生率为21.69%。三个最有效的生物标志物分别是镁、总铁结合能力和白蛋白。总镁值2.0 mg/dL被确定为阈值。镁值低于2.0 mg/dL被认为是房颤阳性,占数据集的25%。总铁结合容量高于442µg/dL被认为是房颤阳性,占数据集的12%。白蛋白的阈值为29 g/dL,低于该值的患者被认为是房颤阳性,占数据集的4%。结论:机器学习模型在识别许多实体的风险因素方面显示出令人鼓舞的结果。最重要的是建立风险因素的排名和确定阈值,以支持临床医生的决策。这是我们第一次在心脏手术后的患者组中使用机器学习。需要进一步的研究来证实这些数据。
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引用次数: 0
Quality of life in patients undergoing lung resection: Evaluation of outcomes of follow-up using brief pain inventory. 肺切除术患者的生活质量:使用简短疼痛量表随访结果的评估。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27233
Seda Kahraman Aydın, Ufuk Çağırıcı, Sercan Aydın, Ayşe Gül Ergönül, Tevfik İlker Akçam, Kutsal Turhan, Ali Özdil, Alpaslan Çakan, Ömer Faruk Dadaş

Background: The aim of the study was to evaluate preoperative anxiety, postoperative pain and functional impairment using Brief Pain Inventory (BPI) in patients undergoing surgery for malignancy.

Methods: Between September 2020 and May 2022, a total of 94 patients (60 males, 34 females; mean age 59.5±12.2 years; range, 32 to 84 years) who underwent surgery for lung cancer were prospectively analyzed. The patients were evaluated using the BPI preoperatively and on postoperative Days 0, 3, and 30. The preoperative emotional impacts of patient variables and the influence of surgical management on postoperative pain were examined.

Results: Females experienced more preoperative emotional distress and insomnia (p=0.046, p=0.033, respectively). Patients diagnosed with cancer and had a history of surgery or thoracotomy demonstrated higher preoperative emotional distress (p=0.001, p<0.001, p<0.001, respectively). Postoperatively, patients who underwent thoracotomy reported greater pain with higher functional impairment compared to the video-assisted thoracoscopic surgery group (p=0.002, p=0.018, respectively). Patients whose drains were completely removed by the postoperative Day 3 had reduced discomfort and improved ability to perform breathing exercise (p=0.005, p=0.045, respectively). Thoracotomy and the placement of double drains were identified as independent factors contributing to difficulties in performing breathing exercises and coughing on Day 30 (p<0.05 for all). There was no significant difference in the pain scores and affected functions between the patients with a thoracotomy incision size of <10 cm and ≥10 cm (p=0.200, p=0.113, respectively).

Conclusion: Our study results indicate that a preference for minimal invasive procedures, the use of a single thoracic drain, and the prompt removal of the drain minimize pain and functional impairment. Women, patients with a preoperative diagnosis of malignancy requiring metastasectomy, and history of thoracotomy or surgery experience elevated levels of anxiety. Therefore, consistent monitoring and psychological support may be recommended to improve the quality of life for this patient population.

背景:本研究的目的是用简短疼痛量表(BPI)评估恶性肿瘤手术患者的术前焦虑、术后疼痛和功能损害。方法:2020年9月至2022年5月,共94例患者(男60例,女34例;平均年龄59.5±12.2岁;范围为32至84岁)接受肺癌手术的患者进行前瞻性分析。术前、术后第0、3、30天采用BPI对患者进行评估。研究了术前患者情绪因素的影响以及手术处理对术后疼痛的影响。结果:女性患者术前情绪困扰和失眠较多(p=0.046, p=0.033)。诊断为癌症且有手术或开胸史的患者术前情绪困扰较高(p=0.001)。结论:我们的研究结果表明,首选微创手术,使用单一胸腔引流管,及时取出引流管可最大限度地减少疼痛和功能损害。女性,术前诊断为恶性肿瘤需要转移切除的患者,以及有开胸或手术史的患者,焦虑水平升高。因此,持续的监测和心理支持可能会被推荐来改善这类患者的生活质量。
{"title":"Quality of life in patients undergoing lung resection: Evaluation of outcomes of follow-up using brief pain inventory.","authors":"Seda Kahraman Aydın, Ufuk Çağırıcı, Sercan Aydın, Ayşe Gül Ergönül, Tevfik İlker Akçam, Kutsal Turhan, Ali Özdil, Alpaslan Çakan, Ömer Faruk Dadaş","doi":"10.5606/tgkdc.dergisi.2025.27233","DOIUrl":"10.5606/tgkdc.dergisi.2025.27233","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study was to evaluate preoperative anxiety, postoperative pain and functional impairment using Brief Pain Inventory (BPI) in patients undergoing surgery for malignancy.</p><p><strong>Methods: </strong>Between September 2020 and May 2022, a total of 94 patients (60 males, 34 females; mean age 59.5±12.2 years; range, 32 to 84 years) who underwent surgery for lung cancer were prospectively analyzed. The patients were evaluated using the BPI preoperatively and on postoperative Days 0, 3, and 30. The preoperative emotional impacts of patient variables and the influence of surgical management on postoperative pain were examined.</p><p><strong>Results: </strong>Females experienced more preoperative emotional distress and insomnia (p=0.046, p=0.033, respectively). Patients diagnosed with cancer and had a history of surgery or thoracotomy demonstrated higher preoperative emotional distress (p=0.001, p<0.001, p<0.001, respectively). Postoperatively, patients who underwent thoracotomy reported greater pain with higher functional impairment compared to the video-assisted thoracoscopic surgery group (p=0.002, p=0.018, respectively). Patients whose drains were completely removed by the postoperative Day 3 had reduced discomfort and improved ability to perform breathing exercise (p=0.005, p=0.045, respectively). Thoracotomy and the placement of double drains were identified as independent factors contributing to difficulties in performing breathing exercises and coughing on Day 30 (p<0.05 for all). There was no significant difference in the pain scores and affected functions between the patients with a thoracotomy incision size of <10 cm and ≥10 cm (p=0.200, p=0.113, respectively).</p><p><strong>Conclusion: </strong>Our study results indicate that a preference for minimal invasive procedures, the use of a single thoracic drain, and the prompt removal of the drain minimize pain and functional impairment. Women, patients with a preoperative diagnosis of malignancy requiring metastasectomy, and history of thoracotomy or surgery experience elevated levels of anxiety. Therefore, consistent monitoring and psychological support may be recommended to improve the quality of life for this patient population.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"238-246"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Truncus bicaroticus and aberrant right subclavian artery: A rare case mimicking aortic dissection. 颈干与右锁骨下动脉异常:一例罕见的主动脉夹层。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.26213
Gokhan Arslan, Ugur Bozlar
{"title":"Truncus bicaroticus and aberrant right subclavian artery: A rare case mimicking aortic dissection.","authors":"Gokhan Arslan, Ugur Bozlar","doi":"10.5606/tgkdc.dergisi.2025.26213","DOIUrl":"10.5606/tgkdc.dergisi.2025.26213","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"257-259"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of mid- and long-term outcomes following carotid endarterectomy with a double-layer primary arteriotomy closure technique. 双层主动脉切开术后颈动脉内膜切除术的中长期疗效评价。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.27226
Hüseyin Ali Tünel, İzzet Hafez, Adem İlkay Diken, Muhammed Onur Hanedan

Background: This study aims to evaluate the mid- and long-term outcomes of patients who underwent carotid endarterectomy with double-layer primary arteriotomy closure technique.

Methods: Between January 2011 and January 2021, a total of 94 patients (58 males, 36 females; mean age: 66.5±8.5 years; range, 40 to 82 years) who underwent carotid endarterectomy were retrospectively analyzed. Doppler ultrasonography, computed tomography or magnetic resonance angiography, and digital subtraction angiography were utilized during follow-up. Stenoses of 50% and above were defined as restenosis.

Results: The mean carotid clamp time was 11.72±2.30 and the mean follow-up was 54.18±27.71 months. Two patients (2.1%) underwent revision due to bleeding and hematoma. No new cerebrovascular events were observed in the postoperative period (<30 days). During the follow-up, six (6.4%) patients with ≥50% stenosis on the same side and 14 (14.9%) patients with stenosis on the opposite side were identified. Primary patency rates were found to be 99% at one year, 95.4% at three years, 90% at five years, 71% at seven years, and 71% at nine years. Age was the only independent risk factor affecting survival.

Conclusion: Our study results suggest that this technique can be used safely in patients with appropriate internal carotid artery diameter with favorable mid- and long-term patency rates.

背景:本研究旨在评估颈动脉内膜切除术合并双层初级动脉切开术的患者的中长期预后。方法:2011年1月至2021年1月,共94例患者(男58例,女36例;平均年龄:66.5±8.5岁;回顾性分析40 - 82岁的颈动脉内膜切除术患者。随访采用多普勒超声、计算机断层或磁共振血管造影、数字减影血管造影。狭窄50%及以上定义为再狭窄。结果:颈动脉夹持时间平均为11.72±2.30个月,平均随访时间为54.18±27.71个月。2例(2.1%)患者因出血和血肿接受翻修。结论:我们的研究结果表明,该技术可以安全地用于内颈动脉直径合适且中长期通畅的患者。
{"title":"Evaluation of mid- and long-term outcomes following carotid endarterectomy with a double-layer primary arteriotomy closure technique.","authors":"Hüseyin Ali Tünel, İzzet Hafez, Adem İlkay Diken, Muhammed Onur Hanedan","doi":"10.5606/tgkdc.dergisi.2025.27226","DOIUrl":"10.5606/tgkdc.dergisi.2025.27226","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the mid- and long-term outcomes of patients who underwent carotid endarterectomy with double-layer primary arteriotomy closure technique.</p><p><strong>Methods: </strong>Between January 2011 and January 2021, a total of 94 patients (58 males, 36 females; mean age: 66.5±8.5 years; range, 40 to 82 years) who underwent carotid endarterectomy were retrospectively analyzed. Doppler ultrasonography, computed tomography or magnetic resonance angiography, and digital subtraction angiography were utilized during follow-up. Stenoses of 50% and above were defined as restenosis.</p><p><strong>Results: </strong>The mean carotid clamp time was 11.72±2.30 and the mean follow-up was 54.18±27.71 months. Two patients (2.1%) underwent revision due to bleeding and hematoma. No new cerebrovascular events were observed in the postoperative period (<30 days). During the follow-up, six (6.4%) patients with ≥50% stenosis on the same side and 14 (14.9%) patients with stenosis on the opposite side were identified. Primary patency rates were found to be 99% at one year, 95.4% at three years, 90% at five years, 71% at seven years, and 71% at nine years. Age was the only independent risk factor affecting survival.</p><p><strong>Conclusion: </strong>Our study results suggest that this technique can be used safely in patients with appropriate internal carotid artery diameter with favorable mid- and long-term patency rates.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"133-143"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Letter to the Editor: Additional insights into the outcomes after combined heart-lung surgery. 致编辑的回复:对心肺联合手术后结果的额外见解。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.50267
Mehmet Şanser Ateş, Zümrüt Tuba Demirözü, Suat Erus, Eray Aksoy, Kadir Burak Özer, Sami Gürkahraman, Ekin Ezgi Cesur, Serhan Tanju
{"title":"Response to Letter to the Editor: Additional insights into the outcomes after combined heart-lung surgery.","authors":"Mehmet Şanser Ateş, Zümrüt Tuba Demirözü, Suat Erus, Eray Aksoy, Kadir Burak Özer, Sami Gürkahraman, Ekin Ezgi Cesur, Serhan Tanju","doi":"10.5606/tgkdc.dergisi.2025.50267","DOIUrl":"10.5606/tgkdc.dergisi.2025.50267","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"267-268"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prognostic value of the TAPSE/PASP ratio in lung transplant candidates. TAPSE/PASP比值在肺移植候选人中的预后价值。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-04-30 eCollection Date: 2025-04-01 DOI: 10.5606/tgkdc.dergisi.2025.26847
Kadir Bıyıklı, Berhan Keskin, Ali Karagöz, Pınar Atagün Güney, Erdal Taşçı, Mustafa Vayvada, Neşri Danışman, Gökhan Alıcı

Background: In this study, we aimed to investigate the prognostic value of the tricuspid annular systolic excursion/pulmonary arterial systolic pressure (TAPSE/PASP) ratio as a marker of right ventricle-pulmonary artery uncoupling in patients listed for lung transplantation.

Methods: Between January 2011 and December 2020, a total of 173 patients (114 males, 59 females; mean age: 53.1±12.5 years; range, 18 to 77 years) who had advanced lung disease or pulmonary vascular disease and were included in the lung transplant list were retrospectively analyzed. Demographic characteristics, laboratory values, long-term mortality data, and clinical and cardiac catheterization data of the patients were compared using a TAPSE/PASP cut-off value of 0.55 mm/mmHg. The univariate and multivariate regression analyses were performed to identify the value of TAPSE/PASP ratio in predicting long-term mortality. The maximal selective rank test was carried out to determine the optimal cut-off value for TAPSE/PASP ratio.

Results: The univariate regression analysis revealed that the TAPSE/PASP ratio, six-minute walk distance, and albumin level were found to be predictors of mortality (hazard ratio [HR]=0.61, 95% confidence interval [CI]: 0.46-0.80, p=0.007; HR=0.72, 95% CI: 0.56-0.91, p=0.007; and HR=0.77, 95% CI: 0.59-0.99, p=0.04, respectively). In the multivariate regression analysis, the TAPSE/PASP ratio, body mass index, and six-minute walk distance were the predictors of mortality (HR=0.49, 95% CI: 0.34-0.70, p=0.004; HR=0.71, 95% CI: 0.51-0.97, p=0.03; and HR=0.71, 95% CI: 0.54-0.94, p=0.01, respectively).Through the maximal selective rank test, the optimal threshold value for TAPSE/PASP ratio was found to be 0.29 mm/mmHg. Patients with TAPSE/PASP >0.29 mm/ mmHg had an average life expectancy of 47.8 months, while the patients with TAPSE/PASP <0.29 mm/mmHg had an average life expectancy of 17.2 months.

Conclusion: Our study results suggest that a TAPSE/PASP ratio of <0.29 mm/mmHg is a poor prognostic factor for long-term mortality in patients on the waiting list for lung transplantation.

背景:在本研究中,我们旨在探讨三尖瓣环收缩偏移/肺动脉收缩压(TAPSE/PASP)比率作为肺移植患者右心室-肺动脉解耦的标志的预后价值。方法:2011年1月至2020年12月,共173例患者(男114例,女59例;平均年龄:53.1±12.5岁;回顾性分析年龄在18岁至77岁之间的晚期肺部疾病或肺血管疾病纳入肺移植名单的患者。采用TAPSE/PASP截断值0.55 mm/mmHg比较患者的人口学特征、实验室值、长期死亡率数据以及临床和心导管数据。进行单因素和多因素回归分析,以确定TAPSE/PASP比值在预测长期死亡率方面的价值。采用最大选择秩检验确定TAPSE/PASP比值的最佳临界值。结果:单因素回归分析显示,TAPSE/PASP比值、6分钟步行距离和白蛋白水平是死亡率的预测因子(风险比[HR]=0.61, 95%可信区间[CI]: 0.46 ~ 0.80, p=0.007;HR=0.72, 95% CI: 0.56 ~ 0.91, p=0.007;HR=0.77, 95% CI: 0.59-0.99, p=0.04)。在多变量回归分析中,TAPSE/PASP比值、体重指数和6分钟步行距离是死亡率的预测因子(HR=0.49, 95% CI: 0.34-0.70, p=0.004;HR=0.71, 95% CI: 0.51 ~ 0.97, p=0.03;HR=0.71, 95% CI: 0.54 ~ 0.94, p=0.01)。通过最大选择秩检验,发现TAPSE/PASP比值的最佳阈值为0.29 mm/mmHg。TAPSE/PASP患者的平均预期寿命为47.8个月,而TAPSE/PASP患者的平均预期寿命为0.29 mm/ mmHg
{"title":"The prognostic value of the TAPSE/PASP ratio in lung transplant candidates.","authors":"Kadir Bıyıklı, Berhan Keskin, Ali Karagöz, Pınar Atagün Güney, Erdal Taşçı, Mustafa Vayvada, Neşri Danışman, Gökhan Alıcı","doi":"10.5606/tgkdc.dergisi.2025.26847","DOIUrl":"10.5606/tgkdc.dergisi.2025.26847","url":null,"abstract":"<p><strong>Background: </strong>In this study, we aimed to investigate the prognostic value of the tricuspid annular systolic excursion/pulmonary arterial systolic pressure (TAPSE/PASP) ratio as a marker of right ventricle-pulmonary artery uncoupling in patients listed for lung transplantation.</p><p><strong>Methods: </strong>Between January 2011 and December 2020, a total of 173 patients (114 males, 59 females; mean age: 53.1±12.5 years; range, 18 to 77 years) who had advanced lung disease or pulmonary vascular disease and were included in the lung transplant list were retrospectively analyzed. Demographic characteristics, laboratory values, long-term mortality data, and clinical and cardiac catheterization data of the patients were compared using a TAPSE/PASP cut-off value of 0.55 mm/mmHg. The univariate and multivariate regression analyses were performed to identify the value of TAPSE/PASP ratio in predicting long-term mortality. The maximal selective rank test was carried out to determine the optimal cut-off value for TAPSE/PASP ratio.</p><p><strong>Results: </strong>The univariate regression analysis revealed that the TAPSE/PASP ratio, six-minute walk distance, and albumin level were found to be predictors of mortality (hazard ratio [HR]=0.61, 95% confidence interval [CI]: 0.46-0.80, p=0.007; HR=0.72, 95% CI: 0.56-0.91, p=0.007; and HR=0.77, 95% CI: 0.59-0.99, p=0.04, respectively). In the multivariate regression analysis, the TAPSE/PASP ratio, body mass index, and six-minute walk distance were the predictors of mortality (HR=0.49, 95% CI: 0.34-0.70, p=0.004; HR=0.71, 95% CI: 0.51-0.97, p=0.03; and HR=0.71, 95% CI: 0.54-0.94, p=0.01, respectively).Through the maximal selective rank test, the optimal threshold value for TAPSE/PASP ratio was found to be 0.29 mm/mmHg. Patients with TAPSE/PASP >0.29 mm/ mmHg had an average life expectancy of 47.8 months, while the patients with TAPSE/PASP <0.29 mm/mmHg had an average life expectancy of 17.2 months.</p><p><strong>Conclusion: </strong>Our study results suggest that a TAPSE/PASP ratio of <0.29 mm/mmHg is a poor prognostic factor for long-term mortality in patients on the waiting list for lung transplantation.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"165-175"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery
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