Coronaviruses causes major economic losses associated with high mortality of domestic animal species. They are widespread in bats worldwide but can infect many other species including birds, camels. cats. dogs. horses, and humans. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) belonging to genus Betacoronavirus associated with human respiratory infections was first detected in the Kingdom of Saudi Arabia in 2012. The Middle East Respiratory Syndrome-related Coronavirus (MERS-CoV) identified in the reservoir Dromedary camels persists to occur in the Middle East in interrupted form. The virus is spread in the infected camels’ secretions especially the nasal tract. Deep studies of the evolution of coronaviruses (MERS-CoVs) are pressingly required. In the current study, we studied amplified fragments of nucleocapsid (N) gene of positive sample from naturally infected dromedary camel comparing with human MERS-CoV strains for tracking the evolution of MERS-CoV over time. RNA was isolated from nasopharyngeal swabs of dromedary camels with suspected MERS-CoV infection. Gel based RT-PCR were analyzed for amplification of variable genomic fragments. Sequence comparisons were carried out through different bioinformatics tools available. Our results showed that there are small changes identified in nucleocapsid gene sequence compared to MERS-CoV-EMC-2012.These changes reported in four codons were found to modified C53T, G69A, C207T and C532T. Phylogenetic analysis using N gene sequence revealed clustering of MERS-CoV strains into three main clades. Eventually, MERS-CoV Shows some evolve. So, it is recommended that the molecular characteristics of future MERS-CoV strains should be analyzed on regular basis to prohibit potential outbreaks in the future
{"title":"Comparative studies on camels and human derived Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in eastern province of Kingdom of Saudi Arabia","authors":"Ali Mohammed Ali","doi":"10.59879/qurjh","DOIUrl":"https://doi.org/10.59879/qurjh","url":null,"abstract":"Coronaviruses causes major economic losses associated with high mortality of domestic animal species. They are widespread in bats worldwide but can infect many other species including birds, camels. cats. dogs. horses, and humans. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) belonging to genus Betacoronavirus associated with human respiratory infections was first detected in the Kingdom of Saudi Arabia in 2012. The Middle East Respiratory Syndrome-related Coronavirus (MERS-CoV) identified in the reservoir Dromedary camels persists to occur in the Middle East in interrupted form. The virus is spread in the infected camels’ secretions especially the nasal tract. Deep studies of the evolution of coronaviruses (MERS-CoVs) are pressingly required. In the current study, we studied amplified fragments of nucleocapsid (N) gene of positive sample from naturally infected dromedary camel comparing with human MERS-CoV strains for tracking the evolution of MERS-CoV over time. RNA was isolated from nasopharyngeal swabs of dromedary camels with suspected MERS-CoV infection. Gel based RT-PCR were analyzed for amplification of variable genomic fragments. Sequence comparisons were carried out through different bioinformatics tools available. Our results showed that there are small changes identified in nucleocapsid gene sequence compared to MERS-CoV-EMC-2012.These changes reported in four codons were found to modified C53T, G69A, C207T and C532T. Phylogenetic analysis using N gene sequence revealed clustering of MERS-CoV strains into three main clades. Eventually, MERS-CoV Shows some evolve. So, it is recommended that the molecular characteristics of future MERS-CoV strains should be analyzed on regular basis to prohibit potential outbreaks in the future","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135612105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and aim: Despite the proven survival benefits of implantable cardioverter-defibrillators, inappropriate shocks limits their benefits due to adverse effects on quality of life, potential arrhythmogenesis an deven on mortality. Atrial fibrillation (AF) is the most common cause of inappropriate shocks. Therefore, to predict and treat AF may prevent inappropriate shocks and their hazardous potentials. This paper aimed to show that by measuring atrial refractoriness, we could predict the patients who may experience inappropriate implantable cardioverter-defibrillator shocks.n Material and methods: 186 consecutive patients who underwent initial ICD implantation underwent coronary angiography and also underwent electrophysiologic (EP) study before the ICD implantation. nResults: Of 169 patients who could be followed, 34 received (20%) at least 1 inappropriate shocks during the mean follow-up of 30 months. Majority of these shocks were due to AF (68%). Atrial effective refactory periods (AERPs) and AERP dispersion were the most significant predictors for these inappropriate shocks. nConclusion: We found that simple EP study parameters measuring atrial refractoriness may define the patients carrying higher risk for future inappropriate shocks due to AF. In these patients, by either device programming or pharmocological treatments or ablation procedures, we could prevent inappropriate shocks and their hazardous results.
{"title":"INCREASED DISPERSION OF ATRIAL REFRACTORINESS PREDICTS MOST OF THE INAPPROPRIATE IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR SHOCKS","authors":"Ozcan Ozdemir, Halil Akin","doi":"10.59879/icquj","DOIUrl":"https://doi.org/10.59879/icquj","url":null,"abstract":"Background and aim: Despite the proven survival benefits of implantable cardioverter-defibrillators, inappropriate shocks limits their benefits due to adverse effects on quality of life, potential arrhythmogenesis an deven on mortality. Atrial fibrillation (AF) is the most common cause of inappropriate shocks. Therefore, to predict and treat AF may prevent inappropriate shocks and their hazardous potentials. This paper aimed to show that by measuring atrial refractoriness, we could predict the patients who may experience inappropriate implantable cardioverter-defibrillator shocks.n Material and methods: 186 consecutive patients who underwent initial ICD implantation underwent coronary angiography and also underwent electrophysiologic (EP) study before the ICD implantation. nResults: Of 169 patients who could be followed, 34 received (20%) at least 1 inappropriate shocks during the mean follow-up of 30 months. Majority of these shocks were due to AF (68%). Atrial effective refactory periods (AERPs) and AERP dispersion were the most significant predictors for these inappropriate shocks. nConclusion: We found that simple EP study parameters measuring atrial refractoriness may define the patients carrying higher risk for future inappropriate shocks due to AF. In these patients, by either device programming or pharmocological treatments or ablation procedures, we could prevent inappropriate shocks and their hazardous results.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135495655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present article reports three simple, sensitive, and accurate spectrophotometric methods which have been progressed for monitoring of clopidogrel bisulphate (CG) in bulk and in pharmaceutical formulations. The three methods are depended on the production of yellow ion-pair complexes between the investigated drug and bromophenol blue (BPB), bromthymol blue (BTB), and bromocresol purple (BCP) as dyes in a universal buffer of pH range (2.0- 4.0). The chloroform was used for formed complexes extraction and measured at 421 nm, 414 nm, and 409 nm, respectively for the three systems. The best conditions of the reactions were tested and optimized. Beer’s law was obeyed in the concentration ranges 2.0 – 18.0 µg mL-1 with molar absorptivity of 4.4 × 104 , 6.4 × 104 and 6.9 × 104 L mol-1cm-1, for the BPB, BTB and BCP methods, respectively. Sandell’s sensitivity, correlation coefficient, quantification and detection limits are also studied. The investigated methods have been achieved successfully for the determination of the drug in pure form and in pharmaceutical formulations. Interference between common pharmaceutical excipients and additives was disappeared. Statistical comparison of the results with those observed by the HPLC method exhibits excellent agreement and shows no significant difference in terms of accuracy and precision.
{"title":"Spectrophotometric Methods for Determination of Clopidogrel in Bulk and in Pharmaceutical Formulations","authors":"Amr Lotfy Saber, R. Shah","doi":"10.59879/ag4zd","DOIUrl":"https://doi.org/10.59879/ag4zd","url":null,"abstract":"The present article reports three simple, sensitive, and accurate spectrophotometric methods which have been progressed for monitoring of clopidogrel bisulphate (CG) in bulk and in pharmaceutical formulations. The three methods are depended on the production of yellow ion-pair complexes between the investigated drug and bromophenol blue (BPB), bromthymol blue (BTB), and bromocresol purple (BCP) as dyes in a universal buffer of pH range (2.0- 4.0). The chloroform was used for formed complexes extraction and measured at 421 nm, 414 nm, and 409 nm, respectively for the three systems. The best conditions of the reactions were tested and optimized. Beer’s law was obeyed in the concentration ranges 2.0 – 18.0 µg mL-1 with molar absorptivity of 4.4 × 104 , 6.4 × 104 and 6.9 × 104 L mol-1cm-1, for the BPB, BTB and BCP methods, respectively. Sandell’s sensitivity, correlation coefficient, quantification and detection limits are also studied. The investigated methods have been achieved successfully for the determination of the drug in pure form and in pharmaceutical formulations. Interference between common pharmaceutical excipients and additives was disappeared. Statistical comparison of the results with those observed by the HPLC method exhibits excellent agreement and shows no significant difference in terms of accuracy and precision.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Die politische Bipolarität der Gesellschaft hat dazu beigetragen, dass das ideologische Konkurrenzdenken sich auch in Literatur reflektiert, die wiederum die gesellschaftlichen Prozesse beeinflusst. Diese Gegensätze haben oft zu Katastrophen (Weltkriege) geführt, die die Autonomität des denkenden Subjekts: während die Moderne sich als Krönung der geistigen Evolution sieht und die Rolle der endgültigen Lösung für sich beansprucht, stellt die Postmoderne all das in Frage und lehnt Dichotomien der Moderne ab. Dagegen charakterisiert sich die Postmoderne mit Anonymität und Identitätslosigkeit, der postmoderne Mensch ist fähig alle Erfahrungen und Informationen des Alltags zu bearbeiten, sein Dasein ist endlich, seine Präsenz vergänglich, seine Möglichkeiten begrenzt. Diese Realität impliziert neue Bedingungen des Alltagslebens, des Arbeits- und Lebensprozesse, in dem das Individuum in einer Diskrepanz mit der wahrnehmbaren Welt existiert und den provisorischen Wahrheiten zum Opfer fällt. Die Degradierung des Individuums in einem passiven Wesen ohne Profil, bringt dazu bei, dass aufgrund diffuser Erfahrungen seinerseits die Wirklichkeit als Unechtheit, als Schein, wahrgenommen wird. Die Evolution der Postmoderne, so Lyotard, kann nur durch das Sprachspiel der Gesellschaft legitimiert werden, wohl gemerkt: das kann nur durch eine Konkurrenz der Machtspiele der Mitglieder zustande kommen.
{"title":"Die literarischen Selbstbeschreibungen der Postmoderne","authors":"Arsim Rexhepi","doi":"10.59879/nmypw","DOIUrl":"https://doi.org/10.59879/nmypw","url":null,"abstract":"Die politische Bipolarität der Gesellschaft hat dazu beigetragen, dass das ideologische Konkurrenzdenken sich auch in Literatur reflektiert, die wiederum die gesellschaftlichen Prozesse beeinflusst. Diese Gegensätze haben oft zu Katastrophen (Weltkriege) geführt, die die Autonomität des denkenden Subjekts: während die Moderne sich als Krönung der geistigen Evolution sieht und die Rolle der endgültigen Lösung für sich beansprucht, stellt die Postmoderne all das in Frage und lehnt Dichotomien der Moderne ab. Dagegen charakterisiert sich die Postmoderne mit Anonymität und Identitätslosigkeit, der postmoderne Mensch ist fähig alle Erfahrungen und Informationen des Alltags zu bearbeiten, sein Dasein ist endlich, seine Präsenz vergänglich, seine Möglichkeiten begrenzt. Diese Realität impliziert neue Bedingungen des Alltagslebens, des Arbeits- und Lebensprozesse, in dem das Individuum in einer Diskrepanz mit der wahrnehmbaren Welt existiert und den provisorischen Wahrheiten zum Opfer fällt. Die Degradierung des Individuums in einem passiven Wesen ohne Profil, bringt dazu bei, dass aufgrund diffuser Erfahrungen seinerseits die Wirklichkeit als Unechtheit, als Schein, wahrgenommen wird. Die Evolution der Postmoderne, so Lyotard, kann nur durch das Sprachspiel der Gesellschaft legitimiert werden, wohl gemerkt: das kann nur durch eine Konkurrenz der Machtspiele der Mitglieder zustande kommen.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wiwik Ambarsari, L. Sulistyowati, Trisna Insan Noor, Eliana Wulandari
Rice farming households with limited capital often employ various strategies to diversify their livelihoods for life sustenance. Therefore, this study aims to determine the effect of the household capital of rice farmers on livelihood diversification in Indramayu District. A survey method was utilized and data were obtained from 214 rice farming households, which were selected using the proportional simple random sampling technique. The data obtained in this study were analyzed using the partial least square method. The results showed that the household capital of rice farmers had a positive and significant effect on livelihood diversification. Based on the findings, government policy recommendations had been prioritized, focusing on physical capital through the provision of agricultural tools and machinery. The government must also prioritize natural, financial, social, and human capital by anticipating climate change, increasing support for capital sources, fostering social networks, and improving farming skills, respectively.
{"title":"LIVELIHOOD DIVERSIFICATION OF RICE FARMER HOUSEHOLDS IN INDRAMAYU DISTRICT, WEST JAVA, INDONESIA","authors":"Wiwik Ambarsari, L. Sulistyowati, Trisna Insan Noor, Eliana Wulandari","doi":"10.59879/ola8r","DOIUrl":"https://doi.org/10.59879/ola8r","url":null,"abstract":"Rice farming households with limited capital often employ various strategies to diversify their livelihoods for life sustenance. Therefore, this study aims to determine the effect of the household capital of rice farmers on livelihood diversification in Indramayu District. A survey method was utilized and data were obtained from 214 rice farming households, which were selected using the proportional simple random sampling technique. The data obtained in this study were analyzed using the partial least square method. The results showed that the household capital of rice farmers had a positive and significant effect on livelihood diversification. Based on the findings, government policy recommendations had been prioritized, focusing on physical capital through the provision of agricultural tools and machinery. The government must also prioritize natural, financial, social, and human capital by anticipating climate change, increasing support for capital sources, fostering social networks, and improving farming skills, respectively.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dejana Trbovic, Mirjana Lukic, Danijela Vranic, Vesna Dordevic, Nikola Stanisic, Nenad Parunovic, Jelena Ciric
There are strong indicators of the link between diets and increased burdens of obesity, cardiovascular diseases, diabetes and some cancers. Healthy dietary patterns were defined as diets that are high in fruits, vegetables and non-fat dairy (low in saturated and trans fats). The aims of this study were to determine the fatty acid (FA) profile of meat (poultry, pork, lamb and beef) and the calculated atherogenic index (AI) and thrombogenic index (TI). Poultry, pork and lamb contained more monounsaturated fatty acids (MUFAs) than saturated fatty acids (SFAs). Linear discriminant analysis (LDA) demonstrated that the first discriminant explained 56.11% of the total variance and the second discriminant explained 23.85% of the total variance. The established p value of Wilks' test was p < 0.0001. By canonical correlation, the first and the second discriminant functions in the LDA were established as 0.995 and 0.995, respectively. AI and TI values of less than 0.5 and 1.0, respectively, were previously advised. The obtained AI values in poultry (0.37-0.45) were lower than those in pork (0.50-0.53), lamb (0.54) and beef (0.93) meats. The obtained TI values in poultry (0.81-0.87) were also lower than in pork (1.09-1.18), lamb (1.44) and beef (1.93) meats. Beneficial nutrition habits, i.e., nutrition according to the food pyramid and a Mediterranean diet, should reduce the rate of coronary heart disease and result in better health outcomes for consumers.
{"title":"Comprehensive levels of fatty acids in meat: implications for human health","authors":"Dejana Trbovic, Mirjana Lukic, Danijela Vranic, Vesna Dordevic, Nikola Stanisic, Nenad Parunovic, Jelena Ciric","doi":"10.59879/de7mq","DOIUrl":"https://doi.org/10.59879/de7mq","url":null,"abstract":"There are strong indicators of the link between diets and increased burdens of obesity, cardiovascular diseases, diabetes and some cancers. Healthy dietary patterns were defined as diets that are high in fruits, vegetables and non-fat dairy (low in saturated and trans fats). The aims of this study were to determine the fatty acid (FA) profile of meat (poultry, pork, lamb and beef) and the calculated atherogenic index (AI) and thrombogenic index (TI). Poultry, pork and lamb contained more monounsaturated fatty acids (MUFAs) than saturated fatty acids (SFAs). Linear discriminant analysis (LDA) demonstrated that the first discriminant explained 56.11% of the total variance and the second discriminant explained 23.85% of the total variance. The established p value of Wilks' test was p < 0.0001. By canonical correlation, the first and the second discriminant functions in the LDA were established as 0.995 and 0.995, respectively. AI and TI values of less than 0.5 and 1.0, respectively, were previously advised. The obtained AI values in poultry (0.37-0.45) were lower than those in pork (0.50-0.53), lamb (0.54) and beef (0.93) meats. The obtained TI values in poultry (0.81-0.87) were also lower than in pork (1.09-1.18), lamb (1.44) and beef (1.93) meats. Beneficial nutrition habits, i.e., nutrition according to the food pyramid and a Mediterranean diet, should reduce the rate of coronary heart disease and result in better health outcomes for consumers.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miao Yu, Shuwei Yang, Fang Shi, Sizhuo Gong, Di Yang, Zihao Lin
In view of the problems that the early warning process of low frequency oscillation in power system is vulnerable to the influence of complex grid environment. The classification speed is slow due to the large amount of processing data in the classification process. A three-stage random forest based on a fuzzy matrix method is proposed in this paper to improve the accuracy and the classification speed of low frequency oscillation early warning in power system. Firstly, the fuzzy matrix comprehensive evaluation is carried out by PMU data, and the evaluation score S will be obtained to determine whether low-frequency oscillation occurs and makes a quick warning. Then, the data is processed by Synchronous Wavelet Transform (SWT), and the damping ratio and attenuation factor of the data are obtained. Furthermore, Random Forest 2(RF 2) and RF 3 are used to judge the type of low frequency oscillation. Finally, simulation results show that the comprehensive fuzzy matrix improves the accuracy of low-frequency oscillation early warning, and the three-stage classification method reduces the amount of data processing and improves the classification speed and stability.
{"title":"A three-stage random forest integrating fuzzy matrix method in low frequency oscillation classification of power system","authors":"Miao Yu, Shuwei Yang, Fang Shi, Sizhuo Gong, Di Yang, Zihao Lin","doi":"10.59879/rfiji","DOIUrl":"https://doi.org/10.59879/rfiji","url":null,"abstract":"In view of the problems that the early warning process of low frequency oscillation in power system is vulnerable to the influence of complex grid environment. The classification speed is slow due to the large amount of processing data in the classification process. A three-stage random forest based on a fuzzy matrix method is proposed in this paper to improve the accuracy and the classification speed of low frequency oscillation early warning in power system. Firstly, the fuzzy matrix comprehensive evaluation is carried out by PMU data, and the evaluation score S will be obtained to determine whether low-frequency oscillation occurs and makes a quick warning. Then, the data is processed by Synchronous Wavelet Transform (SWT), and the damping ratio and attenuation factor of the data are obtained. Furthermore, Random Forest 2(RF 2) and RF 3 are used to judge the type of low frequency oscillation. Finally, simulation results show that the comprehensive fuzzy matrix improves the accuracy of low-frequency oscillation early warning, and the three-stage classification method reduces the amount of data processing and improves the classification speed and stability.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"496 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136303453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Differs to digital innovation, which is application-oriented of digital technologies, digital technology innovation focuses on developing and creating new digital technologies (creation-oriented). Thus, digital technology innovation forms the foundation of digital innovation. Increasingly, firms, especially those in manufacturing, are recognizing the crucial role of digital technology innovation in shaping their intangible value. In order to determine whether digital technology innovation can enhance firm value and the specific mechanism involved, this study draws on patent data (the fields of digital technology are defined based on IPC) and annual report data of listed manufacturing firms in China to reveal the specific relationship between digital technology innovation and the enhancement of firm value. We find that that digital technology innovation can make a significant contribution to firm value; more important, the relationships between digital technology innovation and lowering costs, upgrading efficiency can be characterized as an inverted U-shaped pattern and a Ushaped pattern, respectively. These results hold after the several robustness checks. Additional analyses show that these relationships differ significantly across types of state ownership, firm size, and location feature. Finally, our mechanism analysis suggests that lowering costs and upgrading efficiency driven by digital technology innovation is a key component of the value-enhancing effect.
{"title":"How does digital technology innovation enhance firm value? A dual route model","authors":"Cheng Zhou, Qian Chang","doi":"10.59879/kpbal","DOIUrl":"https://doi.org/10.59879/kpbal","url":null,"abstract":"Differs to digital innovation, which is application-oriented of digital technologies, digital technology innovation focuses on developing and creating new digital technologies (creation-oriented). Thus, digital technology innovation forms the foundation of digital innovation. Increasingly, firms, especially those in manufacturing, are recognizing the crucial role of digital technology innovation in shaping their intangible value. In order to determine whether digital technology innovation can enhance firm value and the specific mechanism involved, this study draws on patent data (the fields of digital technology are defined based on IPC) and annual report data of listed manufacturing firms in China to reveal the specific relationship between digital technology innovation and the enhancement of firm value. We find that that digital technology innovation can make a significant contribution to firm value; more important, the relationships between digital technology innovation and lowering costs, upgrading efficiency can be characterized as an inverted U-shaped pattern and a Ushaped pattern, respectively. These results hold after the several robustness checks. Additional analyses show that these relationships differ significantly across types of state ownership, firm size, and location feature. Finally, our mechanism analysis suggests that lowering costs and upgrading efficiency driven by digital technology innovation is a key component of the value-enhancing effect.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"132 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135104978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The aim of this study is to compare the effectiveness of short-term (6 weeks) and long-term (12 weeks) individual swallowing therapy program in geriatric individuals diagnosed with dysphagia through instrumental evaluation. Method: 127 participants with a mean age of 66.82�16.39 (min=66, max=83) were included in the study. At the beginning of the study, the recordings of the Videofluoroscopy Swallow Study / Modified barium swallow study were scanned and examined, and those with the same dysphagia severity finding who had problems in swallowing safety and efficiency were determined. Patients were randomly assigned to either a short-term intervention group (six weeks; n=62, 48.8%,) or a long-term intervention group (12 weeks; n=65, 51.2%). During Videofluoroscopy, patients were scored with the Penetration-Aspiration Scale by giving food in different consistencies (thin liquid, honey, nectar, pudding, solid consistency) according to the International Dysphagia Dietary Standardization Initiative protocol. Functional Oral Intake Scale and Turkish Eating Assessment Tool results were compared between the groups receiving long-term and short-term swallowing therapy. An exercise-based individual swallowing therapy program was applied to both groups. Results: Penetration aspiration score was higher in the short-term therapy group than in the long-term group. There was a significant difference between the post-therapy penetration aspiration scores of individuals who received long-term and short-term therapy (p<0.001). Pharyngeal phase abnormalities were detected in 81 patients (88.4%), and laryngeal penetration/aspiration status was found in 78 patients (85.3%). Both variables were found to be significantly higher in the short-term group (p:0.015; p:0.014). Turkish eating assessment tool scores were found to be 21.51�3.84 in the long-term group after therapy (p<0.05). Silent aspiration of thin liquid and nectar consistency was experienced in 69% of the patients before the therapy. Conclusion: Long-term swallowing therapy program was proved to be more effective than short-term in geriatric individuals with dysphagia.
{"title":"Examining the Efficacy of Long-Term versus Short-term intervention and that randomized the participants Individual Swallowing Therapy to Improve Optimal Swallowing Physiology in Geriatric Individuals with Dysphagia","authors":"Cagla ELIKUCUK, Fatma ESEN AYDINLI, Didem SENER DEDE, Karabekir ERCAN","doi":"10.59879/bgin0","DOIUrl":"https://doi.org/10.59879/bgin0","url":null,"abstract":"Aim: The aim of this study is to compare the effectiveness of short-term (6 weeks) and long-term (12 weeks) individual swallowing therapy program in geriatric individuals diagnosed with dysphagia through instrumental evaluation. Method: 127 participants with a mean age of 66.82�16.39 (min=66, max=83) were included in the study. At the beginning of the study, the recordings of the Videofluoroscopy Swallow Study / Modified barium swallow study were scanned and examined, and those with the same dysphagia severity finding who had problems in swallowing safety and efficiency were determined. Patients were randomly assigned to either a short-term intervention group (six weeks; n=62, 48.8%,) or a long-term intervention group (12 weeks; n=65, 51.2%). During Videofluoroscopy, patients were scored with the Penetration-Aspiration Scale by giving food in different consistencies (thin liquid, honey, nectar, pudding, solid consistency) according to the International Dysphagia Dietary Standardization Initiative protocol. Functional Oral Intake Scale and Turkish Eating Assessment Tool results were compared between the groups receiving long-term and short-term swallowing therapy. An exercise-based individual swallowing therapy program was applied to both groups. Results: Penetration aspiration score was higher in the short-term therapy group than in the long-term group. There was a significant difference between the post-therapy penetration aspiration scores of individuals who received long-term and short-term therapy (p<0.001). Pharyngeal phase abnormalities were detected in 81 patients (88.4%), and laryngeal penetration/aspiration status was found in 78 patients (85.3%). Both variables were found to be significantly higher in the short-term group (p:0.015; p:0.014). Turkish eating assessment tool scores were found to be 21.51�3.84 in the long-term group after therapy (p<0.05). Silent aspiration of thin liquid and nectar consistency was experienced in 69% of the patients before the therapy. Conclusion: Long-term swallowing therapy program was proved to be more effective than short-term in geriatric individuals with dysphagia.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135495667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashar Ahmed, Uneb Gazder, Khawaja Huzaifa Ahmed, Abdulaziz H. Alshehri, Ahmed Farouk Deifalla, Fayez Alanazi, Ahmed. M. Yosri
This research highlights a very important aspect of road safety which is related to the use of pedestrian facilities by young adults, with special focus on the differences related to gender. Pedestrians are considered as the most vulnerable road user group. Moreover, involvement of young people in road crashes is among the most alarming aspects for most of the countries in the world. This research employs a survey questionnaire to determine the preferences related to use of pedestrian bridge, before and after its rehabilitation. The analysis of the questionnaire included statistical tests, logistic regression and CART model. It was found that the physical condition of the bridge has the most profound effect on the hazard perception of young pedestrians, in spite of the presence of other factors related to safety and security. Most of the pedestrians preferred using the pedestrian bridge during the afternoon, irrespective of the condition of the bridge. It was also found that the before data had a higher impact of gender, with more female respondents showing safety concerns and using the pedestrian bridge. The after data showed a more uniform distribution among genders. Although, the CART model showed significant impact of gender on the perception related to beggars, being the most important risk hazard. It is recommended for future studies to be performed on a larger dataset, include more variables and employ CART technique for modeling.
{"title":"Perceptions and Preferences of University Students for Use of Pedestrian Bridge: A Gender Based Study","authors":"Ashar Ahmed, Uneb Gazder, Khawaja Huzaifa Ahmed, Abdulaziz H. Alshehri, Ahmed Farouk Deifalla, Fayez Alanazi, Ahmed. M. Yosri","doi":"10.59879/a3eia","DOIUrl":"https://doi.org/10.59879/a3eia","url":null,"abstract":"This research highlights a very important aspect of road safety which is related to the use of pedestrian facilities by young adults, with special focus on the differences related to gender. Pedestrians are considered as the most vulnerable road user group. Moreover, involvement of young people in road crashes is among the most alarming aspects for most of the countries in the world. This research employs a survey questionnaire to determine the preferences related to use of pedestrian bridge, before and after its rehabilitation. The analysis of the questionnaire included statistical tests, logistic regression and CART model. It was found that the physical condition of the bridge has the most profound effect on the hazard perception of young pedestrians, in spite of the presence of other factors related to safety and security. Most of the pedestrians preferred using the pedestrian bridge during the afternoon, irrespective of the condition of the bridge. It was also found that the before data had a higher impact of gender, with more female respondents showing safety concerns and using the pedestrian bridge. The after data showed a more uniform distribution among genders. Although, the CART model showed significant impact of gender on the perception related to beggars, being the most important risk hazard. It is recommended for future studies to be performed on a larger dataset, include more variables and employ CART technique for modeling.","PeriodicalId":49454,"journal":{"name":"Sylwan","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：