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BIO-CXRNET: a robust multimodal stacking machine learning technique for mortality risk prediction of COVID-19 patients using chest X-ray images and clinical data. BIO-XRNET:一种强大的多模式叠加机器学习技术,用于使用胸部X射线图像和临床数据预测新冠肺炎患者的死亡率风险。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-05-04 DOI: 10.1007/s00521-023-08606-w
Tawsifur Rahman, Muhammad E H Chowdhury, Amith Khandakar, Zaid Bin Mahbub, Md Sakib Abrar Hossain, Abraham Alhatou, Eynas Abdalla, Sreekumar Muthiyal, Khandaker Farzana Islam, Saad Bin Abul Kashem, Muhammad Salman Khan, Susu M Zughaier, Maqsud Hossain

Nowadays, quick, and accurate diagnosis of COVID-19 is a pressing need. This study presents a multimodal system to meet this need. The presented system employs a machine learning module that learns the required knowledge from the datasets collected from 930 COVID-19 patients hospitalized in Italy during the first wave of COVID-19 (March-June 2020). The dataset consists of twenty-five biomarkers from electronic health record and Chest X-ray (CXR) images. It is found that the system can diagnose low- or high-risk patients with an accuracy, sensitivity, and F1-score of 89.03%, 90.44%, and 89.03%, respectively. The system exhibits 6% higher accuracy than the systems that employ either CXR images or biomarker data. In addition, the system can calculate the mortality risk of high-risk patients using multivariate logistic regression-based nomogram scoring technique. Interested physicians can use the presented system to predict the early mortality risks of COVID-19 patients using the web-link: Covid-severity-grading-AI. In this case, a physician needs to input the following information: CXR image file, Lactate Dehydrogenase (LDH), Oxygen Saturation (O2%), White Blood Cells Count, C-reactive protein, and Age. This way, this study contributes to the management of COVID-19 patients by predicting early mortality risk.

Supplementary information: The online version contains supplementary material available at 10.1007/s00521-023-08606-w.

如今,对新冠肺炎进行快速、准确的诊断是迫切需要。本研究提出了一种多模式系统来满足这一需求。所提出的系统采用机器学习模块,该模块从新冠肺炎第一波疫情期间(2020年3月至6月)在意大利住院的930名新冠肺炎患者收集的数据集中学习所需知识。该数据集由来自电子健康记录和胸部X射线(CXR)图像的25个生物标志物组成。研究发现,该系统可以诊断低风险或高风险患者,准确率、灵敏度和F1评分分别为89.03%、90.44%和89.03%。该系统表现出比使用CXR图像或生物标志物数据的系统高6%的准确性。此外,该系统还可以使用基于多变量逻辑回归的列线图评分技术计算高危患者的死亡风险。感兴趣的医生可以使用所提供的系统,使用网络链接:COVID-severity-grading-AI来预测新冠肺炎患者的早期死亡率风险。在这种情况下,医生需要输入以下信息:CXR图像文件、乳酸脱氢酶(LDH)、血氧饱和度(O2%)、白细胞计数、C反应蛋白和年龄。通过这种方式,这项研究通过预测早期死亡风险,为新冠肺炎患者的管理做出了贡献。补充信息:在线版本包含补充材料,可访问10.1007/s00521-023-08606-w。
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引用次数: 4
A comparative study of anti-swing radial basis neural-fuzzy LQR controller for multi-degree-of-freedom rotary pendulum systems 多自由度转摆系统抗摆径向基神经模糊LQR控制器的比较研究
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-05-03 DOI: 10.1007/s00521-023-08599-6
Zied Ben Hazem, Z. Bingul
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引用次数: 3
A new Covid-19 diagnosis strategy using a modified KNN classifier. 一种新的新冠肺炎诊断策略,使用改进的KNN分类器。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-05-02 DOI: 10.1007/s00521-023-08588-9
Asmaa H Rabie, Alaa M Mohamed, M A Abo-Elsoud, Ahmed I Saleh

Covid-19 is a very dangerous disease as a result of the rapid and unprecedented spread of any previous disease. It is truly a crisis that threatens the world since its first appearance in December 2019 until our time. Due to the lack of a vaccine that has proved sufficiently effective so far, the rapid and more accurate diagnosis of this disease is extremely necessary to enable the medical staff to identify infected cases and isolate them from the rest to prevent further loss of life. In this paper, Covid-19 diagnostic strategy (CDS) as a new classification strategy that consists of two basic phases: Feature selection phase (FSP) and diagnosis phase (DP) has been introduced. During the first phase called FSP, the best set of features in laboratory test findings for Covid-19 patients will be selected using enhanced gray wolf optimization (EGWO). EGWO combines both types of selection techniques called wrapper and filter. Accordingly, EGWO includes two stages called filter stage (FS) and wrapper stage (WS). While FS uses many different filter methods, WS uses a wrapper method called binary gray wolf optimization (BGWO). The second phase called DP aims to give fast and more accurate diagnosis using a hybrid diagnosis methodology (HDM) based on the selected features from FSP. In fact, the HDM consists of two phases called weighting patient phase (WP2) and diagnostic patient phase (DP2). WP2 aims to calculate the belonging degree of each patient in the testing dataset to class category using naïve Bayes (NB) as a weight method. On the other hand, K-nearest neighbor (KNN) will be used in DP2 based on the weights of patients in the testing dataset as a new training dataset to give rapid and more accurate detection. The suggested CDS outperforms other strategies according to accuracy, precision, recall (or sensitivity) and F-measure calculations that are equal to 99%, 88%, 90% and 91%, respectively, as showed in experimental results.

新冠肺炎是一种非常危险的疾病,因为以前任何疾病都会迅速、前所未有地传播。自2019年12月首次出现以来,直到我们这个时代,这确实是一场威胁世界的危机。由于缺乏迄今为止证明足够有效的疫苗,对这种疾病进行快速、更准确的诊断是极其必要的,以使医务人员能够识别感染病例并将其与其他人隔离,防止进一步的生命损失。本文介绍了新冠肺炎诊断策略(CDS)作为一种新的分类策略,它由两个基本阶段组成:特征选择阶段(FSP)和诊断阶段(DP)。在名为FSP的第一阶段,将使用增强灰狼优化(EGWO)选择新冠肺炎患者实验室检测结果的最佳特征集。EGWO结合了两种类型的选择技术,称为包装器和过滤器。因此,EGWO包括两个阶段,称为过滤阶段(FS)和包装阶段(WS)。虽然FS使用许多不同的过滤方法,但WS使用一种称为二进制灰狼优化(BGWO)的包装方法。第二阶段称为DP,旨在使用基于FSP所选特征的混合诊断方法(HDM)进行快速、更准确的诊断。事实上,HDM由两个阶段组成,称为加权患者阶段(WP2)和诊断患者阶段(DP2)。WP2旨在使用朴素贝叶斯(NB)作为权重方法来计算测试数据集中每个患者对类别的归属度。另一方面,基于测试数据集中患者的权重,将在DP2中使用K近邻(KNN)作为新的训练数据集,以提供快速、更准确的检测。实验结果显示,所提出的CDS在准确度、精密度、召回率(或灵敏度)和F-测量计算方面优于其他策略,分别为99%、88%、90%和91%。
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引用次数: 0
MOCOVIDOA: a novel multi-objective coronavirus disease optimization algorithm for solving multi-objective optimization problems. MOCOVIDOA:一种新的多目标冠状病毒疾病优化算法,用于解决多目标优化问题。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-05-02 DOI: 10.1007/s00521-023-08587-w
Asmaa M Khalid, Hanaa M Hamza, Seyedali Mirjalili, Khaid M Hosny

A novel multi-objective Coronavirus disease optimization algorithm (MOCOVIDOA) is presented to solve global optimization problems with up to three objective functions. This algorithm used an archive to store non-dominated POSs during the optimization process. Then, a roulette wheel selection mechanism selects the effective archived solutions by simulating the frameshifting technique Coronavirus particles use for replication. We evaluated the efficiency by solving twenty-seven multi-objective (21 benchmarks & 6 real-world engineering design) problems, where the results are compared against five common multi-objective metaheuristics. The comparison uses six evaluation metrics, including IGD, GD, MS, SP, HV, and delta p (ΔP). The obtained results and the Wilcoxon rank-sum test show the superiority of this novel algorithm over the existing algorithms and reveal its applicability in solving multi-objective problems.

提出了一种新的多目标冠状病毒疾病优化算法(MOCOVIDOA),用于解决多达三个目标函数的全局优化问题。该算法在优化过程中使用了一个档案来存储非支配POS。然后,轮盘选择机制通过模拟冠状病毒颗粒用于复制的移帧技术来选择有效的存档解决方案。我们通过解决27个多目标(21个基准和6个真实世界的工程设计)问题来评估效率,其中将结果与五种常见的多目标元启发式方法进行比较。比较使用了六个评估指标,包括IGD、GD、MS、SP、HV和Δp。所获得的结果和Wilcoxon秩和检验表明了该新算法相对于现有算法的优越性,并揭示了其在解决多目标问题中的适用性。
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引用次数: 1
A new classification method for diagnosing COVID-19 pneumonia based on joint CNN features of chest X-ray images and parallel pyramid MLP-mixer module. 一种新的诊断新冠肺炎肺炎的分类方法,基于胸部X射线图像的联合CNN特征和平行金字塔MLP-mixer模块。
IF 4.5 3区 计算机科学 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2023-04-28 DOI: 10.1007/s00521-023-08604-y
Yiwen Liu, Wenyu Xing, Mingbo Zhao, Mingquan Lin

During the past three years, the coronavirus disease 2019 (COVID-19) has swept the world. The rapid and accurate recognition of covid-19 pneumonia are ,therefore, of great importance. To handle this problem, we propose a new pipeline of deep learning framework for diagnosing COVID-19 pneumonia via chest X-ray images from normal, COVID-19, and other pneumonia patients. In detail, the self-trained YOLO-v4 network was first used to locate and segment the thoracic region, and the output images were scaled to the same size. Subsequently, the pre-trained convolutional neural network was adopted to extract the features of X-ray images from 13 convolutional layers, which were fused with the original image to form a 14-dimensional image matrix. It was then put into three parallel pyramid multi-layer perceptron (MLP)-Mixer modules for comprehensive feature extraction through spatial fusion and channel fusion based on different scales so as to grasp more extensive feature correlation. Finally, by combining all image features from the 14-channel output, the classification task was achieved using two fully connected layers as well as Softmax classifier for classification. Extensive simulations based on a total of 4099 chest X-ray images were conducted to verify the effectiveness of the proposed method. Experimental results indicated that our proposed method can achieve the best performance in almost all cases, which is good for auxiliary diagnosis of COVID-19 and has great clinical application potential.

在过去三年中,2019冠状病毒病(新冠肺炎)席卷全球。因此,快速准确地识别新冠肺炎肺炎具有重要意义。为了解决这个问题,我们提出了一种新的深度学习框架,用于通过正常、新冠肺炎和其他肺炎患者的胸部X光图像诊断COVID-19]肺炎。详细地说,首先使用自训练的YOLO-v4网络来定位和分割胸部区域,并将输出图像缩放到相同的大小。随后,采用预先训练的卷积神经网络从13个卷积层中提取X射线图像的特征,并将其与原始图像融合,形成14维图像矩阵。然后将其放入三个平行金字塔多层感知器(MLP)-混合器模块中,通过基于不同尺度的空间融合和通道融合进行综合特征提取,以掌握更广泛的特征相关性。最后,通过组合14通道输出的所有图像特征,使用两个完全连接的层以及Softmax分类器进行分类,实现了分类任务。基于总共4099张胸部X射线图像进行了广泛的模拟,以验证所提出方法的有效性。实验结果表明,我们提出的方法几乎在所有病例中都能达到最佳性能,有利于新冠肺炎的辅助诊断,具有很大的临床应用潜力。
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引用次数: 0
Time-series benchmarks based on frequency features for fair comparative evaluation. 基于频率特征的时间序列基准,用于公平的比较评估。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-04-22 DOI: 10.1007/s00521-023-08562-5
Zhou Wu, Ruiqi Jiang

Time-series prediction and imputation receive lots of attention in academic and industrial areas. Machine learning methods have been developed for specific time-series scenarios; however, it is difficult to evaluate the effectiveness of a certain method on other new cases. In the perspective of frequency features, a comprehensive benchmark for time-series prediction is designed for fair evaluation. A prediction problem generation process, composed of the finite impulse response filter-based approach and problem setting module, is adopted to generate the NCAA2022 dataset, which includes 16 prediction problems. To reduce the computational burden, the filter parameters matrix is divided into sub-matrices. The discrete Fourier transform is introduced to analyze the frequency distribution of transformed results. In addition, a baseline experiment further reflects the benchmarking capability of NCAA2022 dataset.

时间序列的预测和插补在学术界和工业界都受到了广泛的关注。已经为特定的时间序列场景开发了机器学习方法;然而,很难评估某一方法在其他新案例中的有效性。从频率特征的角度出发,设计了一个时间序列预测的综合基准,以实现公平评价。采用基于有限脉冲响应滤波器的方法和问题设置模块组成的预测问题生成过程来生成NCAA2022数据集,该数据集包括16个预测问题。为了减少计算负担,将滤波器参数矩阵划分为子矩阵。引入离散傅立叶变换来分析变换结果的频率分布。此外,基线实验进一步反映了NCAA2022数据集的基准测试能力。
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引用次数: 2
An intelligent identification and classification system for malicious uniform resource locators (URLs). 一种用于恶意统一资源定位器(URL)的智能识别和分类系统。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-04-20 DOI: 10.1007/s00521-023-08592-z
Qasem Abu Al-Haija, Mustafa Al-Fayoumi

Uniform Resource Locator (URL) is a unique identifier composed of protocol and domain name used to locate and retrieve a resource on the Internet. Like any Internet service, URLs (also called websites) are vulnerable to compromise by attackers to develop Malicious URLs that can exploit/devastate the user's information and resources. Malicious URLs are usually designed with the intention of promoting cyber-attacks such as spam, phishing, malware, and defacement. These websites usually require action on the user's side and can reach users across emails, text messages, pop-ups, or devious advertisements. They have a potential impact that can reach, in some cases, to compromise the machine or network of the user, especially those arriving by email. Therefore, developing systems to detect malicious URLs is of great interest nowadays. This paper proposes a high-performance machine learning-based detection system to identify Malicious URLs. The proposed system provides two layers of detection. Firstly, we identify the URLs as either benign or malware using a binary classifier. Secondly, we classify the URL classes based on their feature into five classes: benign, spam, phishing, malware, and defacement. Specifically, we report on four ensemble learning approaches, viz. the ensemble of bagging trees (En_Bag) approach, the ensemble of k-nearest neighbor (En_kNN) approach, and the ensemble of boosted decision trees (En_Bos) approach, and the ensemble of subspace discriminator (En_Dsc) approach. The developed approaches have been evaluated on an inclusive and contemporary dataset for uniform resource locators (ISCX-URL2016). ISCX-URL2016 provides a lightweight dataset for detecting and categorizing malicious URLs according to their attack type and lexical analysis. Conventional machine learning evaluation measurements are used to evaluate the detection accuracy, precision, recall, F Score, and detection time. Our experiential assessment indicates that the ensemble of bagging trees (En_Bag) approach provides better performance rates than other ensemble methods. Alternatively, the ensemble of the k-nearest neighbor (En_kNN) approach provides the highest inference speed. We also contrast our En_Bag model with state-of-the-art solutions and show its superiority in binary classification and multi-classification with accuracy rates of 99.3% and 97.92%, respectively.

统一资源定位器(URL)是一个由协议和域名组成的唯一标识符,用于在互联网上定位和检索资源。与任何互联网服务一样,URL(也称为网站)很容易受到攻击者的攻击,从而开发出可以利用/破坏用户信息和资源的恶意URL。恶意URL的设计通常旨在促进网络攻击,如垃圾邮件、网络钓鱼、恶意软件和污损。这些网站通常需要用户采取行动,可以通过电子邮件、短信、弹出窗口或狡猾的广告联系用户。它们具有潜在的影响,在某些情况下,可能会危及用户的机器或网络,尤其是那些通过电子邮件到达的用户。因此,开发检测恶意URL的系统是当今人们非常感兴趣的。本文提出了一种基于机器学习的高性能恶意URL检测系统。所提出的系统提供了两层检测。首先,我们使用二进制分类器将URL识别为良性或恶意。其次,我们根据URL类的特征将其分为五类:良性、垃圾邮件、网络钓鱼、恶意软件和污损。具体而言,我们报告了四种集成学习方法,即套袋树集成(En_Bag)方法、k近邻集成(En_kNN)方法、增强决策树集成(En_Bos)方法和子空间鉴别器集成(En_Dsc)方法。已在统一资源定位器的包容性和当代数据集(ISCX-URL2016)上对所开发的方法进行了评估。ISCX-URL2016提供了一个轻量级数据集,用于根据恶意URL的攻击类型和词法分析对其进行检测和分类。传统的机器学习评估测量用于评估检测准确性、精确度、召回率、F分数和检测时间。我们的经验评估表明,套袋树集成(En_Bag)方法比其他集成方法提供了更好的性能。或者,k近邻(En_kNN)方法的集合提供了最高的推理速度。我们还将我们的En_Bag模型与最先进的解决方案进行了比较,并展示了其在二元分类和多分类方面的优势,准确率分别为99.3%和97.92%。
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引用次数: 5
Quantized ℋ∞ stabilization for delayed memristive neural networks 时滞记忆神经网络的量化h∞镇定
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-04-19 DOI: 10.1007/s00521-023-08510-3
Zhilian Yan, Dandan Zuo, Tong Guo, Jianping Zhou
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引用次数: 1
MVDroid: an android malicious VPN detector using neural networks. MVDroid:一个使用神经网络的安卓恶意VPN检测器。
IF 4.5 3区 计算机科学 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2023-04-03 DOI: 10.1007/s00521-023-08512-1
Saeed Seraj, Siavash Khodambashi, Michalis Pavlidis, Nikolaos Polatidis

The majority of Virtual Private Networks (VPNs) fail when it comes to protecting our privacy. If we are using a VPN to protect our online privacy, many of the well-known VPNs are not secure to use. When examined closely, VPNs can appear to be perfect on the surface but still be a complete privacy and security disaster. Some VPNs will steal our bandwidth, infect our computers with malware, install secret tracking libraries on our devices, steal our personal data, and leave our data exposed to third parties. Generally, Android users should be cautious when installing any VPN software on their devices. As a result, it is important to identify malicious VPNs before downloading and installing them on our Android devices. This paper provides an optimised deep learning neural network for identifying fake VPNs, and VPNs infected by malware based on the permissions of the apps, as well as a novel dataset of malicious and benign Android VPNs. Experimental results indicate that our proposed classifier identifies malicious VPNs with high accuracy, while it outperforms other standard classifiers in terms of evaluation metrics such as accuracy, precision, and recall.

当涉及到保护我们的隐私时,大多数虚拟专用网络(VPN)都会失败。如果我们使用VPN来保护我们的在线隐私,那么许多知名的VPN使用起来并不安全。当仔细检查时,VPN表面上看起来很完美,但仍然是一场完全的隐私和安全灾难。一些VPN会窃取我们的带宽,用恶意软件感染我们的计算机,在我们的设备上安装秘密跟踪库,窃取我们的个人数据,并将我们的数据暴露给第三方。一般来说,安卓用户在设备上安装任何VPN软件时都应谨慎。因此,在我们的Android设备上下载和安装恶意VPN之前,识别它们是很重要的。本文提供了一个优化的深度学习神经网络,用于根据应用程序的权限识别假VPN和被恶意软件感染的VPN,以及一个新的恶意和良性Android VPN数据集。实验结果表明,我们提出的分类器识别恶意VPN的准确率很高,而在准确性、准确度和召回率等评估指标方面,它优于其他标准分类器。
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引用次数: 0
Machine learning based multipurpose medical image watermarking. 基于机器学习的多用途医学图像水印。
IF 6 3区 计算机科学 Q1 Computer Science Pub Date : 2023-03-24 DOI: 10.1007/s00521-023-08457-5
Rishi Sinhal, Irshad Ahmad Ansari

Digital data security has become an exigent area of research due to a huge amount of data availability at present time. Some of the fields like medical imaging and medical data sharing over communication platforms require high security against counterfeit access, manipulation and other processing operations. It is essential because the changed/manipulated data may lead to erroneous judgment by medical experts and can negatively influence the human's heath. This work offers a blind and robust medical image watermarking framework using deep neural network to provide effective security solutions for medical images. During watermarking, the region of interest (ROI) data of the original image is preserved by employing the LZW (Lampel-Ziv-Welch) compression algorithm. Subsequently the robust watermark is inserted into the original image using IWT (integer wavelet transform) based embedding approach. Next, the SHA-256 algorithm-based hash keys are generated for ROI and RONI (region of non-interest) regions. The fragile watermark is then prepared by ROI recovery data and the hash keys. Further, the LSB replacement-based insertion mechanism is utilized to embed the fragile watermark into RONI embedding region of robust watermarked image. A deep neural network-based framework is used to perform robust watermark extraction for efficient results with less computational time. Simulation results verify that the scheme has significant imperceptibility, efficient robust watermark extraction, correct authentication and completely reversible nature for ROI recovery. The relative investigation with existing schemes confirms the dominance of the proposed work over already existing work.

由于目前数据量巨大,数字数据安全已成为一个迫切需要研究的领域。一些领域,如医疗成像和通过通信平台共享医疗数据,需要高度安全性,以防止伪造访问、操纵和其他处理操作。这一点至关重要,因为更改/操纵的数据可能会导致医学专家的错误判断,并对人类健康产生负面影响。该工作提供了一个使用深度神经网络的盲鲁棒医学图像水印框架,为医学图像提供了有效的安全解决方案。在水印过程中,通过采用LZW(Lampel-Ziv-Welch)压缩算法来保留原始图像的感兴趣区域(ROI)数据。随后,使用基于IWT(整数小波变换)的嵌入方法将鲁棒水印插入到原始图像中。接下来,针对ROI和RONI(非感兴趣区域)区域生成基于SHA-256算法的散列密钥。然后通过ROI恢复数据和散列密钥来准备脆弱水印。此外,利用基于LSB替换的插入机制将脆弱水印嵌入到鲁棒水印图像的RONI嵌入区域中。使用基于深度神经网络的框架来执行鲁棒水印提取,以获得计算时间较少的有效结果。仿真结果验证了该方案具有显著的不可见性、高效的鲁棒水印提取、正确的认证和完全可逆的ROI恢复特性。与现有方案的相对调查证实了拟议工作相对于现有工作的主导地位。
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引用次数: 1
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Neural Computing & Applications
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