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[The Nobel Prize in Physiology or Medicine 2023]. 2023年诺贝尔生理学或医学奖。
IF 0.4 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-01 DOI: 10.17992/lbl.2023.12.769
Ingileif Jonsdottir
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引用次数: 0
[A 50 year old man with progressive weakness in lower limbs]. [一名50岁的男子,下肢逐渐衰弱]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-11-01 DOI: 10.17992/lbl.2023.11.768
Brynhildur Thors, Bjarni Gudmundsson

Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare neurological disorder caused by autoimmune antibodies attacking the presynaptic neuromuscular junction, in some cases caused by underlying cancer. The main clinical finding is fluctuating weakness of the extremities and a triad of symtoms can help physicians suspect the disease. A key to the diagnosis are the electrophysiological abnormalities seen in this group of diseases. Treatment with symtomatic and/or immunosuppressive therapy is important as well as a workup for possible malignancy. This article identifies the clinical features, diagnosis and treatment of this uncommon disease.

Lambert-Eaton肌肉无力综合征(LEMS)是一种罕见的神经系统疾病,由自身免疫抗体攻击突触前神经肌肉接头引起,在某些情况下由潜在的癌症引起。主要的临床发现是四肢无力的波动,三重症状可以帮助医生怀疑这种疾病。诊断的关键是在这组疾病中发现的电生理异常。症状和/或免疫抑制疗法的治疗以及可能的恶性肿瘤的检查都很重要。本文对这种罕见疾病的临床特点、诊断和治疗进行了阐述。
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引用次数: 0
[Major increase in the incidence of cirrhosis in Iceland]. [冰岛肝硬化发病率大幅上升]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-11-01 DOI: 10.17992/lbl.2023.11.764
Sigurdur Olafsson
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引用次数: 0
[Psychedelics and treatment of mental disorders: A survey of attitudes and knowledge among psychiatrists, general practitioners and psychologists in Iceland]. [迷幻药和精神障碍的治疗:冰岛精神病学家、全科医生和心理学家的态度和知识调查]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-11-01 DOI: 10.17992/lbl.2023.11.766
Ragnar P Olafsson, Karol Kvaran, Kristin Ketilsdottir, Kolbrun Hallgrimsdottir, Emil L Sigurdsson, Engilbert Sigurdsson

Introduction: Interest in the use of psychedelics has increased following reports of their possible therapeutic potential. However, little is known about the knowledge of and attitudes towards the substances among health care professional who provide treatment for mental disorders in Iceland. An online survey was therefore conducted among members of the Icelandic associations of psychiatrists, general practitioners and psychologists.

Methods: Respondents were 256 in total, including 177 psychologists, 38 psychiatrists and 41 general practitioners that provided information on their background, type of work, knowledge of and attitude towards different types of psychedelic substances and their views on optimal service delivery if psychedelics were approved by licencing authorities and used for treatment.

Results: Around half of psychiatrists reported having received questions about treatment with psychedelics in their clinical work, compared to only 14,6% of general practitioners and 17,5% of psychologists. The majority of respondents had little, or no knowledge of the substances targeted in the survey. A majority also expressed negative attitudes towards treatment with psilocybin mushrooms, but was positive towards ongoing scientific research and felt that such a treatment should be prescribed and provided by psychiatrists. Moreover, the majority view was that psilocybin treatment should be provided in specialised clinics or psychiatric units in a hospital setting. Scientific articles on the topic, discussions with colleagues and information in the media were identified as having had most influence on respondents´ attitudes towards psychedelics. Most respondents were interested in further education on psychedelics.

Conclusions: Respondents among these three professions felt that the time has not yet come to use psychedelics in the treatment of mental disorders in Iceland but thought more education on psychedelics, their potential efficacy and adverse health effects is important given the increased interest in psychedelics.

引言:人们对迷幻药的使用越来越感兴趣,因为有报道称其可能具有治疗潜力。然而,在冰岛,为精神障碍提供治疗的卫生保健专业人员对这些物质的了解和态度知之甚少。因此,在冰岛精神病学家、全科医生和心理学家协会的成员中进行了一项在线调查。方法:共有256名受访者,包括177名心理学家、38名精神科医生和41名全科医生,他们提供了关于他们的背景、工作类型、对不同类型的迷幻药的知识和态度的信息,以及他们对如果迷幻药被许可证颁发机构批准并用于治疗时提供最佳服务的看法。结果:大约一半的精神科医生报告说,他们在临床工作中收到过有关迷幻药治疗的问题,而全科医生和心理学家的这一比例分别为14.6%和17.5%。大多数受访者对调查所针对的物质知之甚少或一无所知。大多数人也对裸盖菇的治疗持负面态度,但对正在进行的科学研究持积极态度,并认为这种治疗应该由精神科医生开具处方和提供。此外,大多数人认为裸盖菇素治疗应在医院的专门诊所或精神科提供。关于这一主题的科学文章、与同事的讨论以及媒体上的信息被认为对受访者对迷幻药的态度影响最大。大多数受访者对进一步的迷幻药教育感兴趣。结论:这三种职业的受访者认为,在冰岛,使用迷幻药治疗精神障碍的时机还没有到来,但他们认为,鉴于人们对迷幻药的兴趣越来越大,对迷幻剂及其潜在疗效和不良健康影响进行更多的教育很重要。
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引用次数: 0
[Shortages of medications in Iceland. Local reasons?] [冰岛药品短缺。当地原因?]
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-11-01 DOI: 10.17992/lbl.2023.11.765
Ragnar Bjarnason
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引用次数: 0
[Pneumococcal meningitis in children in Iceland - case report and summary]. [冰岛儿童肺炎球菌脑膜炎病例报告和总结]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-11-01 DOI: 10.17992/lbl.2023.11.767
Jens Stensrud, Oskar Orn Oskarsson, Helga Erlendsdottir, Valtyr Stefansson Thors

An eleven month old girl was referred to the pediatric emergency department at Landspitali Hospital due to fever and lethargy. On examination she was acutely ill with fluctuating level of conciousness. She deteriorated quickly after arrival at the emergency department and was diagnosed with pneumococcal meningitis. In the past year several cases of bacterial meningitis have been diagnosed with Streptococcus pneumoniae as the most common pathogen. The disease causing serotypes have been serotypes that were not in the vaccine that was used in iceland and the Icelandic health authorities have decided to change the vaccination programme accordingly.

一名11个月大的女孩因发烧和嗜睡被转诊至兰兹医院儿科急诊科。经过检查,她病得很厉害,意识水平起伏不定。她在到达急诊室后病情迅速恶化,被诊断为肺炎球菌脑膜炎。在过去的一年中,一些细菌性脑膜炎病例被诊断为肺炎链球菌是最常见的病原体。致病血清型是冰岛使用的疫苗中没有的血清型,冰岛卫生当局已决定相应地改变疫苗接种计划。
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引用次数: 0
[Epidemiology of polypharmacy in primary healthcare in the Reykjavik metropolitan area 2010-2019]. 【2010-2019年雷克雅未克大都市地区初级保健多药流行病学】。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-10-01 DOI: 10.17992/lbl.2023.10.762
Dagur Andri Fridgeirsson Hjaltalin, Jon Steinar Jonsson, Kristjan Linnet, Emil Larus Sigurdsson, Anna Bryndis Blondal

Introduction: Taking medicines can induce risks leading to negative health issues that can grow in accordance with the number of medicines used. Many studies on the prevalence of polypharmacy have been carried out in other countries, but such studies are lacking in Iceland. The aim of this study was to analyse the prevalence of polypharmacy in primary care in the Reykjavik metropolitan area.

Methods: The study population consisted of individuals who had been prescribed five or more drugs by physicians in primary care in the Reykjavik metropolitan area during the study period. Data was collected on all drug prescriptions for individuals in the area. Those who had five or more drugs prescribed in the primary healthcare database from 1 January 2010 through 31 December 2019 were included in the study. According to Statistics Iceland, the total number of inhabitants in the area was 200.907 in 2010 and 228.222 in 2019.

Findings: The prevalence of polypharmacy increased gradually in 2010-2019, or by 37.9% during this period. Patients with polypharmacy were 9.8% (19.778) at the beginning of the study in 2010 and increased to 13.6% (30.970) in 2019. A clear association was observed between age and polypharmacy, and the study showed polypharmacy to be more common among women. The study findings revealed that the greatest relative increase in polypharmacy was among young people from 20-49 years of age. ATC class analysis showed a sharp increase in the first and third levels of the ATC subgroups.

Conclusion: The findings suggest polypharmacy to be common in the Reykjavik metropolitan area. Similarly, its prevalence seems to be increasing in younger patients. It is important to gain a better understanding of the reasons for the development of polypharmacy and evaluate the increasing medicalisation in society. The underlying reasons, as well as the effects of polypharmacy, can lead to both positive and negative health outcomes.

引言:服用药物会引发风险,导致负面健康问题,这些问题会随着药物使用数量的增加而增加。其他国家对多种药物的流行情况进行了许多研究,但冰岛缺乏此类研究。本研究的目的是分析雷克雅未克大都市地区初级保健中多药治疗的流行情况。方法:研究人群包括在研究期间由雷克雅未克大都市地区初级保健医生开了五种或五种以上药物的个人。收集了该地区个人所有药物处方的数据。从2010年1月1日到2019年12月31日,在初级保健数据库中有五种或五种以上药物的患者被纳入研究。根据冰岛统计局的数据,2010年该地区的居民总数为200.907人,2019年为228.222人。调查结果:2010-2019年,多种药物的流行率逐渐上升,在此期间上升了37.9%。2010年研究开始时,多药治疗患者占9.8%(19.778),2019年增至13.6%(30.970)。观察到年龄和多药治疗之间存在明显的关联,研究表明多药治疗在女性中更常见。研究结果显示,多药治疗的相对增长最大的是20-49岁的年轻人。ATC类别分析显示,ATC亚组的第一级和第三级急剧增加。结论:研究结果表明,多药治疗在雷克雅未克大都市地区很常见。同样,它在年轻患者中的流行率似乎在增加。更好地理解多药治疗发展的原因并评估社会中日益增长的药物化是很重要的。潜在的原因,以及多药治疗的影响,可以导致积极和消极的健康结果。
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引用次数: 0
[Simulation in medical education in Iceland]. [冰岛医学教育模拟]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-10-01 DOI: 10.17992/lbl.2023.10.761
Elsa Valsdottir, Hans Haraldsson, Asta Bryndís Schram, Peter Dieckmann

Background: Skills labs and simulation centers have become an integrated part of teaching methods in many medical schools. This study aims to describe the status of simulation in medical education in Iceland by examining student and faculty experience, facilitating and barring factors for its use in teaching and how the concept appears in the Course Catalog.

Materials and methods: The study was threefold. In parts one and two, electronic surveys were sent to students and faculty members at the Faculty of Medicine, University of Iceland. Part three was a key word search in the University´s course catalogue relating to simulation.

Results: Response rate for both student and faculty surveys was 65%. Simulation as a teaching method was reported for 10% of faculty according to students but approximately a third of faculty, according to faculty. Attitudes of students and faculty were positive. Faculty, previously exposed to simulation, were more likely to use simulation, as were those who had received training in educational methods. Main barriers identified were lack of facilities, equipment, funds, and training. Key words related to simulation appeared rarely in the University Course Catalogue.

Conclusion: Student and faculty experience with simulation is limited, less than third of faculty claim to have used simulation when teaching medical students. Barring factors in Iceland are similar to what has been reported elsewhere. Lack of words describing simulation in the Course Catalog may raise questions about emphasis on teaching methods or lack thereof. Potential ways to increase the use of simulation could be to improve infrastructure and offer training in diverse educational methods, including simulation, to selected faculty.

背景:技能实验室和模拟中心已经成为许多医学院教学方法的一个组成部分。本研究旨在通过考察学生和教师的经验、在教学中使用模拟的促进因素和阻碍因素,以及该概念如何出现在课程目录中,来描述模拟在冰岛医学教育中的地位。材料和方法:本研究分为三个方面。在第一部分和第二部分中,向冰岛大学医学院的学生和教职员工发送了电子调查。第三部分是大学模拟课程目录中的关键词检索。结果:学生和教师调查的回复率均为65%。据报道,模拟作为一种教学方法,有10%的教师根据学生的说法,但大约有三分之一的教师根据教师的说法。学生和教职员工的态度都是积极的。以前接触过模拟的教师更有可能使用模拟,接受过教育方法培训的教师也是如此。发现的主要障碍是缺乏设施、设备、资金和培训。与模拟相关的关键词很少出现在《大学课程目录》中。结论:学生和教师在模拟方面的经验有限,只有不到三分之一的教师声称在教授医学生时使用过模拟。冰岛的障碍因素与其他地方报道的情况相似。课程目录中缺乏描述模拟的词语可能会引发对教学方法的重视或缺乏的问题。增加模拟使用的潜在方法可能是改善基础设施,并为选定的教师提供包括模拟在内的多种教育方法的培训。
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引用次数: 0
[Export of knowledge jobs]. [知识型工作的输出]。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-10-01 DOI: 10.17992/lbl.2023.10.760
Magnus Gottfredsson
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引用次数: 0
[Migration of an intrauterine contraceptive device outside of the uterine cavity - a case report]. 【宫内节育器移出宫腔一例报告】。
IF 0.4 4区 医学 Q4 Medicine Pub Date : 2023-10-01 DOI: 10.17992/lbl.2023.10.763
Gudrun Margret Vidarsdottir, Asgeir Bodvarsson, Helgi Kjartan Sigurdsson, Pall Helgi Moller

Intrauterine devices (IUDs) are a safe and common form of contraception. Uterine rupture and migration of the IUD is a rare complication of insertion but can be serious and cause damage to adjacent organs. We present a case report of a 43 year old woman with chronic abdominal pain who was diagnosed with an IUD in the wall of the sigmoid colon. That IUD had been inserted in the uterine cavity 22 years earlier.

宫内节育器是一种安全而常见的避孕方式。宫内节育器的子宫破裂和移位是一种罕见的插入并发症,但可能很严重,并对邻近器官造成损害。我们报告了一例43岁的慢性腹痛妇女,她被诊断为乙状结肠壁有宫内节育器。宫内节育器早在22年前就已植入子宫腔。
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引用次数: 0
期刊
Laeknabladid
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