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Oral Hairy Leukoplakia in Patients With No Evidence of Immunosuppression: A Case Series and Review of the Literature. 无免疫抑制证据的口腔毛状白斑:一个病例系列和文献综述。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-05-01
Mark Roger Darling, Morad Alkhasawneh, Wendall Mascarenhas, Alexandra Chirila, Maria Copete

Objectives: Oral hairy leukoplakia (OHL) is caused by Epstein-Barr virus (EBV) and is often associated with HIV and other immunosuppressive conditions. It is rare in HIV-negative patients, but has been reported in patients who use immune-modulating medications (e.g., cyclosporine). The objectives of this study were to determine the occurrence of OHL in HIV-negative patients and report Langerhans cell counts in these lesions.

Study design: A series of 7 new cases of OHL among HIV-negative patients is described. Langerhans cells were counted using an immunoperoxidase stain for CD1a and light microscopy.

Results: The 7 patients were male, ranging in age from 26 to 69 years. Clinically, all lesions were diagnosed as leukoplakia on the lateral border of the tongue. Microscopic examination revealed hyperparakeratosis and candidiasis in some cases, acanthosis and a band-like zone with clearing of cells in the upper spinous layer, which were EBV-positive by in-situ hybridization. There was a significant decrease in Langerhans cell counts in OHL patients.

Conclusion: OHL can occur in HIV-negative patients.

目的:口腔毛状白斑(OHL)是由eb病毒(EBV)引起的,通常与HIV和其他免疫抑制疾病有关。它在hiv阴性患者中很少见,但在使用免疫调节药物(如环孢素)的患者中有报道。本研究的目的是确定艾滋病毒阴性患者中OHL的发生率,并报告这些病变中的朗格汉斯细胞计数。研究设计:描述了一系列hiv阴性患者中7例新的OHL病例。使用CD1a免疫过氧化物酶染色和光镜对朗格汉斯细胞进行计数。结果:7例患者为男性,年龄26 ~ 69岁。临床均诊断为舌侧缘白斑。镜检显示部分病例角化过度,念珠菌感染,棘层增生,棘层上部细胞清除带状带,原位杂交显示ebv阳性。OHL患者朗格汉斯细胞计数明显下降。结论:OHL可发生于hiv阴性患者。
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引用次数: 0
Comparison of the contact angle of water on set elastomeric impression materials. 水在固定弹性压印材料上的接触角比较。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-05-01
Usama Nassar, Faraz Tavoossi, Yan Wen Pan, Nathan Milavong-Viravongsa, Giseon Heo, John A Nychka

Purpose: The hydrophilicity of some elastomeric impression materials has not been fully established. The purpose of this study was to measure and compare the advancing contact angle of water on the surface of several set elastomeric impression materials.

Materials and methods: We tested various consistencies of vinyl polysiloxane (VPS; Imprint 4) and vinyl polyether silicone (VPES; EXA'lence) with a polyether (PE; Impregum Soft) control. Impression discs (25.07 mm) were made using a metal die and ring. Deionized ultra-filtered water was placed on each disc and contact-angle measurements were made at 0, 15, 30, 45 and 60 s using a video contact angle drop shape analysis machine. The data were analyzed using repeated ANOVA and a post-hoc test with Bonferroni correction.

Results: VPS contact angles reached a mean of 10.1° ± 0.2° at 60 s vs. 40.7° ± 0.1° for VPES. Overall, VPS contact angles were smaller than those for VPES at all measured times. However, heavy and super quick heavy VPS had much higher contact angles at 0 s compared with other VPS consistencies. There was a significant difference in contact angles between VPS and VPES (mean difference 33.9°, p < 0.05) and between VPS and PE (mean difference 32.8°, p < 0.05) but not between VPES and PE (P = 0.196). VPS heavy and super quick heavy were significantly different from other VPS materials (p < 0.05), but not from each other (p = 1.00).

Conclusions: Set VPS is more hydrophilic than VPES. Contact-angle values of VPS indicated super hydrophilicity. VPES was hydrophilic, with measurements similar to the PE control. Thus, VPS impression materials may be excellent in terms of spreading and copying wet surfaces.

目的:一些弹性体印模材料的亲水性尚未完全确定。本研究的目的是测量和比较几种固定的弹性体印模材料表面的水的推进接触角。材料和方法:我们测试了不同浓度的乙烯基聚硅氧烷(VPS;压印4)和乙烯基聚醚有机硅(VPES;EXA'lence)与聚醚(PE;软)控制。压印盘(25.07毫米)是用金属模具和环制成的。在每个圆盘上放置去离子水,在0、15、30、45和60 s使用视频接触角液滴形状分析机进行接触角测量。使用重复方差分析和Bonferroni校正的事后检验对数据进行分析。结果:VPS 60 s接触角平均值为10.1°±0.2°,VPES为40.7°±0.1°。总体而言,在所有测量时间,VPS的接触角都小于VPES。而重VPS和超快重VPS在0 s时的接触角比其他VPS一致性高得多。VPS与VPES的接触角差异有统计学意义(平均差33.9°,p < 0.05), VPS与PE的接触角差异有统计学意义(平均差32.8°,p < 0.05),但VPES与PE的接触角差异无统计学意义(p = 0.196)。VPS重料和超快重料与其他VPS材料差异显著(p < 0.05),但彼此间差异不显著(p = 1.00)。结论:Set VPS的亲水性优于VPES。VPS的接触角值显示出超亲水性。VPES具有亲水性,其测量结果与PE对照组相似。因此,VPS压印材料在湿表面的扩散和复制方面可能是优秀的。
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引用次数: 0
More than Just Pulling Teeth: The Impact of Dental Care on Patients' Lived Experiences. 不仅仅是拔牙:牙科护理对患者生活体验的影响。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-05-01
Loretta Kerr

Objectives: To explore the psychosocial impacts of dentistry as described by patients.

Methods: I conducted 6 qualitative interviews with people whose access to dental care had been limited because of financial barriers, but who had recently undergone significant treatment through a dental outreach program.

Results: In addition to physical benefits (including improved sleep and diet), participants discussed how dental treatment led to a greater level of confidence and an improved self-concept. They provided powerful examples of how this confidence boost improved their social interactions and relationships. They also felt more confident about their employability.

Conclusion: The benefits of adequate dental care extend well beyond its physical and medical aspects. Dental health is connected inextricably with people's sense of self and social functioning. The far-reaching consequences of dentistry explored in this research raise questions about the inequalities in Canada's current system and the need to address them.

目的:探讨牙科治疗对患者心理社会的影响。方法:我进行了6次定性访谈,访谈对象是由于经济障碍而无法获得牙科护理,但最近通过牙科外展计划接受了重要治疗的人。结果:除了身体上的好处(包括改善睡眠和饮食),参与者还讨论了牙科治疗如何提高信心和改善自我概念。他们提供了强有力的例子,说明这种自信是如何改善他们的社会交往和人际关系的。他们对自己的就业能力也更有信心。结论:充分的牙齿护理的好处远远超出了它的身体和医疗方面。牙齿健康与人的自我意识和社会功能密不可分。本研究探讨了牙科的深远影响,提出了有关加拿大现行制度不平等的问题,并需要解决这些问题。
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引用次数: 0
Accuracy of Thermosensitive Microsensors Intended to Monitor Patient Use of Removable Oral Appliances. 用于监测患者使用可移动口腔器械的热敏微传感器的准确性。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-05-01
Stacey Kirshenblatt, Hui Chen, Marijke Dieltjens, Benjamin Pliska, Fernanda R Almeida

Objective: The aim of this study was to evaluate the accuracy of 3 thermosensitive microsensors that record "wear time" of removable oral appliances (OAs).

Methods: For in vitro testing, TheraMon (sensor T, n = 20), AIR-AID SLEEP (sensor A, n = 30) and DentiTrac (sensor D, n = 16) microsensors were placed in a water bath to simulate long and short durations of wear. Their accuracy was also assessed when they were embedded in 3 materials: acrylic, polyvinylchloride and thermoactive acrylic. In vivo testing included 14 volunteers, who wore maxillary retainers embedded with sensors A and D for 30 nights. Logs of appliance use were compared with readouts from the sensors.

Results: In the in vitro long duration of wear assessment, sensor A, with a mean absolute response difference (MARD) of 1.67 min. (SD 1.41), was significantly more accurate than sensor T (MARD 3.53 min., SD 9.80) and sensor D (MARD 4.48 min., SD 8.46). For short duration of wear, sensor A (MARD 1.41 min., SD 3.60) and sensor T (MARD 1.68 min., SD 7.64) were equal in accuracy and significantly better than sensor D (MARD 14.07 min., SD 10.20). The embedding material had no effect on the recording accuracies of the microsensors. In vivo, there was no significant difference between sensors A and D.

Conclusion: All 3 microsensors are highly accurate and reliable and can be used to record wear time of a removable OAs fabricated from various materials.

目的:本研究的目的是评估3种记录可摘口腔矫治器(OAs)“磨损时间”的热敏微传感器的准确性。方法:在体外测试中,将TheraMon(传感器T, n = 20)、AIR-AID SLEEP(传感器A, n = 30)和DentiTrac(传感器D, n = 16)微传感器置于水浴中,模拟长时间和短时间的磨损。当它们嵌入3种材料时,也评估了它们的准确性:丙烯酸、聚氯乙烯和热活性丙烯酸。体内测试包括14名志愿者,他们戴上装有传感器A和D的上颌固位器30晚。电器使用日志与传感器的读数进行了比较。结果:在体外长时间磨损评估中,传感器A的平均绝对响应差(MARD)为1.67 min (SD 1.41),显著高于传感器T (MARD 3.53 min, SD 9.80)和传感器D (MARD 4.48 min, SD 8.46)。在较短的磨损时间内,传感器A (MARD 1.41 min, SD 3.60)和传感器T (MARD 1.68 min, SD 7.64)的精度相同,且显著优于传感器D (MARD 14.07 min, SD 10.20)。包埋材料对微传感器的记录精度没有影响。结论:3种微传感器均具有较高的测量精度和可靠性,可用于记录各种材料制成的可拆卸oa的磨损时间。
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引用次数: 0
Adherence to Treatment with Removable Oral Appliances: the Past and the Future. 坚持使用可移动口腔矫治器治疗:过去和未来。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-04-01
Stacey Kirshenblatt, Hui Chen, Marijke Dieltjens, Benjamin Pliska, Fernanda R Almeida

Oral appliances (OAs) are frequently used in orthodontics and for the treatment of obstructive sleep apnea. Because OAs can be inserted and removed by patients themselves, the patient's cooperation is a major component of effective treatment. In this review, we provide an overview of factors studied in the past that affect adherence to OA use in orthodontics and dental sleep medicine. We also describe future directions in adherence and the use of objective microsensor technology to measure adherence in these patients. Because removable oral appliances (OAs) can be inserted and removed by patients themselves, their cooperation and adherence to therapy are necessary to achieve success.1,2 Removable OAs, such as headgear, removable retainers and functional appliances, are used in orthodontics to correct malocclusions. In the field of sleep medicine, removable OAs are increasingly used as an option in the treatment of patients with obstructive sleep apnea (OSA).

口腔矫治器(OAs)经常用于正畸和治疗阻塞性睡眠呼吸暂停。由于oa可以由患者自己插入和取出,因此患者的配合是有效治疗的主要组成部分。在这篇综述中,我们概述了过去研究的影响正畸和牙科睡眠医学中OA使用依从性的因素。我们还描述了依从性和使用客观微传感器技术来测量这些患者的依从性的未来方向。由于可移动口腔矫治器(OAs)可以由患者自己插入和取出,因此他们的合作和坚持治疗是取得成功的必要条件。1,2可移动的牙齿矫正器,如头套、可移动固位器和功能性矫治器,用于正畸矫正错牙。在睡眠医学领域,可拆卸oa越来越多地被用作治疗阻塞性睡眠呼吸暂停(OSA)患者的一种选择。
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引用次数: 0
Biochemical Stability and Interactions of Dental Resin Composites and Adhesives with Host and Bacteria in the Oral Cavity: A Review. 口腔树脂复合材料和黏合剂的生物化学稳定性及其与宿主和细菌的相互作用综述。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2018-01-01
Maher Bourbia, Yoav Finer

The use of resin composites and adhesives in dental restorations is ubiquitous. However, the longevity of resin composites is less than that of comparable restorative materials, mainly because of higher fracture rates and greater prevalence of secondary caries. Dental resin composites and adhesives contain ester links, which are vulnerable to biochemical hydrolysis by esterase activity from human saliva and bacteria. In this article, we review biodegradation processes that occur in the oral cavity and their contribution to the premature failure of resin composites. Biodegradation causes deterioration of resin composite bulk and the composite-tooth interface and releases by-products, such as methacrylic acid, triethylene glycol and bishydroxy-propoxy-phenyl-propane. These by-products have been shown to affect cariogenic bacterial growth and virulence. A compromised restoration-tooth interface allows saliva and oral bacteria to infiltrate the spaces between the tooth and the composite, exacerbating the effects of biodegradation, undermining the restoration and leading to recurrent caries, hypersensitivity and pulpal inflammation. It is important to consider the biochemical stability of these materials to advance their chemistry beyond the current formulations and conceive more biochemically stable and better-performing dental resin composites and adhesives.

树脂复合材料和黏合剂在牙齿修复中的应用是普遍存在的。然而,树脂复合材料的寿命比同类修复材料要短,主要是因为树脂复合材料的骨折率更高,继发性龋齿的发生率更高。牙科树脂复合材料和粘合剂含有酯链,易被人类唾液和细菌的酯酶活性生化水解。在本文中,我们回顾了发生在口腔中的生物降解过程及其对树脂复合材料过早失效的贡献。生物降解导致树脂复合体和复合齿界面劣化,释放出甲基丙烯酸、三甘醇和双羟基丙氧基苯基丙烷等副产物。这些副产品已被证明影响龋齿细菌的生长和毒力。一个受损的修复体-牙齿界面允许唾液和口腔细菌渗透到牙齿和复合材料之间的空间,加剧生物降解的影响,破坏修复并导致复发性龋齿,过敏和牙髓炎症。重要的是要考虑这些材料的生化稳定性,以推动其化学性质超越目前的配方,并构想出更多的生化稳定性和性能更好的牙科树脂复合材料和粘合剂。
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引用次数: 0
Culturally adapted musical intervention for patient-centred health care. 适应文化的音乐干预,以病人为中心的卫生保健。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2017-12-01
Elham Emami, Nathalie Gosselin, Pierre Rainville, Robert Durand
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引用次数: 0
The Perfect Storm: What's Pushing Canadians Abroad for Dental Care? 完美风暴:是什么促使加拿大人出国接受牙科护理?
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2017-10-01
Krystyna Adams, Jeremy Snyder, Valorie A Crooks

We examine the perspectives of 14 key informants with extensive knowledge of dental care provision in Canada regarding systemic factors that could push Canadians to participate in dental tourism. Drawing on interview discussions about Canadians' access to dental care and their participation in dental tourism, we identify systemic factors related to how dental care is financed and delivered, rising costs of dental care and consumerism in terms of their potential role in Canadians' decisions to purchase dental care abroad. Further research on individual experiences accessing and using dental care, both in Canada and abroad, could help provide a better understanding of how these factors are informing Canadians' decision-making regarding dental care and, as a result, access to needed care.

我们研究了14个关键线人的观点,他们广泛了解加拿大牙科保健提供的系统性因素,这些因素可能推动加拿大人参与牙科旅游。通过对加拿大人获得牙科护理和参与牙科旅游的采访讨论,我们确定了与牙科护理如何融资和交付、牙科护理成本上升和消费主义有关的系统性因素,这些因素在加拿大人决定购买国外牙科护理方面的潜在作用。对在加拿大和国外获得和使用牙科护理的个人经历进行进一步研究,可以帮助更好地了解这些因素如何影响加拿大人对牙科护理的决策,从而获得所需的护理。
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引用次数: 0
Sterilization of Ceramic Sharpening Stones. 陶瓷磨刀石的灭菌。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2017-09-01
Colin B Wiebe, Bonnie J Hoath, Gethin Owen, Jiarui Bi, Georgios Giannelis, Hannu S Larjava

Traditionally, periodontal hand instruments are honed or sharpened during patient care as they dull easily during contact with enamel, calculus and cementum. This approach is taught in dental and hygiene schools around the world and remains the standard of care. Recently, some professional organizations have questioned whether this practice should be abandoned because of safety issues. Questions have been raised whether sharpening stones can be properly sterilized and whether the sharpening of contaminated instruments poses a health hazard for the provider. Using bacteria culture techniques and scanning electron microscopy, we tested whether contaminated ceramic sharpening stones can be sterilized. Our results demonstrate that the stones were sterile after being subjected to the manufacturer's sterilization protocol. In addition, over the last year, no incidents related to periodontal instrument sharpening have been reported among nearly 400 students at the faculty of dentistry, University of British Columbia, where chair-side sharpening is taught. Therefore, we conclude that ceramic sharpening stones can be sterilized using normal office protocols and that chair-side sharpening adds little risk beyond routine handling of operatory or periodontal instruments during patient care when proper protocols are followed.

传统上,牙周手工工具在病人护理期间被打磨或磨尖,因为它们在接触牙釉质、牙石和牙骨质时很容易变钝。世界各地的牙科和卫生学校都在教授这种方法,并且仍然是标准的护理方法。最近,一些专业组织质疑这种做法是否应该因为安全问题而被放弃。人们提出的问题是,磨刀石是否可以适当消毒,以及磨砺受污染的工具是否会对提供者的健康造成危害。利用细菌培养技术和扫描电镜技术,对受污染的陶瓷磨刀石进行了灭菌试验。我们的结果表明,石头是无菌后,受到制造商的灭菌方案。此外,在过去的一年里,在英属哥伦比亚大学(University of British Columbia)教授椅子边磨刀术的牙科学院的近400名学生中,没有发生与牙周器械磨刀有关的事故。因此,我们得出结论,陶瓷磨刀石可以使用正常的办公室协议进行消毒,并且在患者护理期间,如果遵循适当的协议,椅子边的磨刀石除了常规处理手术或牙周器械外,几乎没有增加风险。
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引用次数: 0
Antibiotic and Opioid Analgesic Prescribing Patterns of Dentists in Vancouver and Endodontic Specialists in British Columbia. 温哥华牙医和不列颠哥伦比亚省牙髓专家的抗生素和阿片类镇痛药处方模式。
IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2017-09-01
Rene Buttar, Jolanta Aleksejūnienė, Jeffrey Coil

Aim: To assess the prescribing decisions of general dentists in Vancouver and endodontists in British Columbia regarding analgesics and antibiotics for patients with endodontic disease. An additional aim was to determine whether gender, clinical experience or practice location have an impact on such decisions.

Methods: A 4-page survey was developed and distributed to approximately half the general dentists in Vancouver (n = 259) and all of the endodontists in British Columbia (n = 50). Basic demographic questions were followed by 7 clinical scenarios and a list of endodontic diagnoses. Participants were asked questions regarding their decisions to prescribe analgesics and antibiotics.

Results: The overall response rate was 49%: 72% of endodontists responded, compared with 45% of general dentists. A substantial proportion of clinicians prescribed opioid analgesics and antibiotics in the various clinical scenarios. The rate of prescription of opioid analgesics ranged from 4%-47% for the various scenarios; the rate of prescription of antibiotics was 5%-88%. General dentists reported prescribing opioid analgesics and antibiotics more often than endodontists. Gender, clinical experience and practice location did not seem to have an impact on the decision to prescribe opioid analgesics or antibiotics.

Conclusions: Based on the results of our survey, a significant proportion of dental professionals in British Columbia prescribe opioid analgesics and antibiotics during endodontic procedures when they are likely not required. General dentists tend to prescribe these medications more often than endodontists. We found no apparent differences in terms of gender, clinical experience or practice location. Dentists must be conscientious when prescribing these medications as over-prescription has negative consequences.

目的:评估温哥华的普通牙医和不列颠哥伦比亚省的牙髓科医生对牙髓疾病患者的镇痛药和抗生素的处方决定。另一个目的是确定性别、临床经验或实践地点是否对这些决定有影响。方法:开发了一份4页的调查,并分发给温哥华大约一半的普通牙医(n = 259)和不列颠哥伦比亚省所有的牙髓科医生(n = 50)。基本的人口统计问题之后是7个临床场景和牙髓诊断列表。参与者被问及关于他们决定开止痛药和抗生素的问题。结果:总体反应率为49%:牙髓科医生的反应率为72%,而普通牙医的反应率为45%。相当比例的临床医生处方阿片类镇痛药和抗生素在各种临床情况。阿片类镇痛药的处方率在4% ~ 47%之间;抗菌药物处方率为5% ~ 88%。普通牙医比牙髓医生更常开阿片类镇痛药和抗生素。性别、临床经验和执业地点似乎对开阿片类镇痛药或抗生素的决定没有影响。结论:根据我们的调查结果,在不列颠哥伦比亚省,很大比例的牙科专业人员在牙髓治疗过程中可能不需要使用阿片类镇痛药和抗生素。普通牙医往往比牙髓科医生更经常开这些药。我们发现在性别、临床经验或执业地点方面没有明显差异。牙医在开这些药的时候必须谨慎,因为过度开处方会产生负面后果。
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引用次数: 0
期刊
Journal of the Canadian Dental Association
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