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Clinical effectiveness study of the new diagnostic score of acute appendicitis in the elderly 老年急性阑尾炎新诊断评分的临床疗效研究
Pub Date : 2023-09-01 DOI: 10.52645/mjhs.2023.3.04
Alexandr Gaitur
Introduction. Acute appendicitis is among the three most frequent surgical diseases. The lifetime likelihood of developing acute appendicitis is around 7%. The incidence of acute appendicitis reduces with age after adolescence. Several studies evaluated the relevance of the current scores to the general population, mostly children, but a limited number of studies have studied the elderly population. This study aims to assess the clinical effectiveness of the new diagnostic score for the elderly population in comparison to both the Alvarado score and the non-standardized score. Material and methods. In order to evaluate the effectiveness of the diagnostic score of acute appendicitis, we examined 78 patients who were admitted to emergency unit of the Saint Archangel Michael Municipal Clinical Hospital during 20182021 with the presumptive diagnosis of acute appendicitis. Of all patients admitted, Acute Appendicitis was confirmed on pathological examination in 22 (28.2%) patients. The average age of patients was 73.5±13.5 years (minimum - 60 years, maximum - 87 years). The ratio of males to females was 1:1.6. Results. Comparative evaluation of the new diagnostic score of acute appendicitis and the non-standardized clinical-echographic examination for acute appendicitis diagnosis showed better performance indicators of the new diagnostic score of acute appendicitis compared to the non-standardized clinical method for acute appendicitis diagnosis. The high sensitivity of the new diagnostic score of acute appendicitis was statistically demonstrated (ƛ2 = 4.32; p < 0.05), a lower rate of missed acute appendicitis cases in the new diagnostic score of acute appendicitis (ƛ2 = 4.32; p < 0.05), the „grey area” is lower in the new diagnostic score of acute appendicitis (ƛ2 = 5.28; p < 0.05), than in the non-standardized diagnosis. It was shown to have a lower rate of acute appendicitis cases in the „grey area” of the total number of acute appendicitis cases (ƛ2 = 4.9; p < 0.05). Benchmarking indicators such as specificity and diagnostic accuracy showed no statistically significant differences. At the same time, a definite increase in specificity and accuracy was observed for the new diagnostic score of acute appendicitis compared to non-standardized clinical diagnosis. Conclusions. Diagnosing acute appendicitis in elderly patients remains challenging due to the numerous potential diagnoses with similar clinical manifestations that are observed in this patient population. It was necessary to utilize clinical risk-scoring systems that could aid in the prompt identification of patients with acute appendicitis. This study concludes that the New diagnostic score has higher clinical efficiency in diagnosing acute appendicitis in elderly patients. It has a sensitivity of up to 93.15%, compared to the unstandardized clinical method and the Alvarado diagnostic score, and is independent of „risk factors” such as obesity and atypical vermiform appendix localization.
介绍。急性阑尾炎是三种最常见的外科疾病之一。一生中患急性阑尾炎的可能性约为7%。青春期后,急性阑尾炎的发病率随年龄的增长而降低。几项研究评估了当前得分与一般人群(主要是儿童)的相关性,但研究老年人的研究数量有限。本研究旨在评估新诊断评分与Alvarado评分和非标准化评分在老年人群中的临床效果。材料和方法。为了评价急性阑尾炎诊断评分的有效性,我们对2018 - 2021年期间在圣大天使迈克尔市临床医院急诊科推定诊断为急性阑尾炎的78例患者进行了调查。在所有住院患者中,22例(28.2%)患者病理检查证实为急性阑尾炎。患者平均年龄73.5±13.5岁(最小- 60岁,最大- 87岁)。男女比例为1:6 .6。结果。对比评价急性阑尾炎新诊断评分与非标准化临床超声检查诊断急性阑尾炎的表现,新诊断评分优于非标准化临床方法诊断急性阑尾炎的表现指标。新诊断评分对急性阑尾炎的敏感性有统计学意义(ƛ2 = 4.32;p & lt;0.05),急性阑尾炎新诊断评分漏诊率较低(ƛ2 = 4.32;p & lt;0.05),急性阑尾炎新诊断评分“灰色区域”较低(ƛ2 = 5.28;p & lt;0.05),高于非标准化诊断。结果显示,在急性阑尾炎病例总数的“灰色区域”,急性阑尾炎病例的发生率较低(ƛ2 = 4.9;p & lt;0.05)。特异性、诊断准确性等基准指标差异无统计学意义。同时,与非标准化临床诊断相比,新的急性阑尾炎诊断评分的特异性和准确性明显提高。结论。老年患者急性阑尾炎的诊断仍然具有挑战性,因为在该患者群体中观察到许多具有相似临床表现的潜在诊断。有必要利用临床风险评分系统,可以帮助及时识别急性阑尾炎患者。本研究认为新诊断评分对老年急性阑尾炎有较高的临床诊断效率。与不规范的临床方法和Alvarado诊断评分相比,其敏感性高达93.15%,且不受肥胖、不典型蚓状阑尾定位等“危险因素”的影响。
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Moldovan Journal of Health Sciences
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