Pub Date : 2023-09-15DOI: 10.32474/papn.2023.04.000193
Leonor Esteves Caldeira
Background: Tree nuts and peanuts (TN/P) are frequent causes of anaphylaxis in children. Aim: to characterize a Portuguese pediatric cohort with TN/P allergy and to assess skin tests (ST), specific IgE (sIgE) and molecular components (mcIgE), as well as sIgE/total IgE ratio’s utility in anaphylaxis prediction. Methods: Retrospective study (2017-2021) of pediatric patients with TN/P allergy, grouped according to reaction severity (anaphylaxis–G1 vs milder reaction–G2). ST mean papule diameter (MPD), sIgE (ImmunoCAP ® ), mcIgE (ISAC ® ) and sIgE/total IgE ratio were compared (SPSS ® , p < 0.05: statistically significant). Results: 98 patients, 64% male, 88% concomitant allergic disorder, 40% allergy family history. Major culprit nuts: peanut (63%), hazelnut (59%) and walnut (53%). Index reaction manifestations were mostly cutaneous (46%), followed by anaphylaxis (36%). Chestnut and cashew sensitizations were significantly associated with anaphylaxis (OR=5.023, p=0.002; OR=2.901, p=0.018). MPD was higher in G1 for almond, cashew and pistachio (p < 0.05). sIgE was not a good severity predictor for any TN/P, however, a significantly higher value of sIgE/total IgE ratio was found in G1 for walnut (p=0.023). mcIgE was obtained in 49%: peanut Ara h2 and Ara h6 were more represented in G1 (2.8 vs 0 ISU-E, p=0.042; 1.3 vs 0 ISU-E, p=0.020). Conclusion: Peanut, hazelnut and walnut were the most frequent nuts. Anaphylaxis was the first manifestation in 36%, significantly higher in chestnut and cashew allergic children. MPD should be valued not only for diagnosis, but also for anaphylaxis risk prediction in almond, cashew and pistachio allergic patients. sIgE/total IgE ratio seems to be useful in anaphylaxis prediction.
{"title":"Tree Nut and Peanut Allergy in a Portuguese Pediatric Cohort- Clinical Characterization and Anaphylaxis PredictorsLeonor Esteves","authors":"Leonor Esteves Caldeira","doi":"10.32474/papn.2023.04.000193","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000193","url":null,"abstract":"Background: Tree nuts and peanuts (TN/P) are frequent causes of anaphylaxis in children. Aim: to characterize a Portuguese pediatric cohort with TN/P allergy and to assess skin tests (ST), specific IgE (sIgE) and molecular components (mcIgE), as well as sIgE/total IgE ratio’s utility in anaphylaxis prediction. Methods: Retrospective study (2017-2021) of pediatric patients with TN/P allergy, grouped according to reaction severity (anaphylaxis–G1 vs milder reaction–G2). ST mean papule diameter (MPD), sIgE (ImmunoCAP ® ), mcIgE (ISAC ® ) and sIgE/total IgE ratio were compared (SPSS ® , p < 0.05: statistically significant). Results: 98 patients, 64% male, 88% concomitant allergic disorder, 40% allergy family history. Major culprit nuts: peanut (63%), hazelnut (59%) and walnut (53%). Index reaction manifestations were mostly cutaneous (46%), followed by anaphylaxis (36%). Chestnut and cashew sensitizations were significantly associated with anaphylaxis (OR=5.023, p=0.002; OR=2.901, p=0.018). MPD was higher in G1 for almond, cashew and pistachio (p < 0.05). sIgE was not a good severity predictor for any TN/P, however, a significantly higher value of sIgE/total IgE ratio was found in G1 for walnut (p=0.023). mcIgE was obtained in 49%: peanut Ara h2 and Ara h6 were more represented in G1 (2.8 vs 0 ISU-E, p=0.042; 1.3 vs 0 ISU-E, p=0.020). Conclusion: Peanut, hazelnut and walnut were the most frequent nuts. Anaphylaxis was the first manifestation in 36%, significantly higher in chestnut and cashew allergic children. MPD should be valued not only for diagnosis, but also for anaphylaxis risk prediction in almond, cashew and pistachio allergic patients. sIgE/total IgE ratio seems to be useful in anaphylaxis prediction.","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-14DOI: 10.32474/papn.2023.04.000194
Tolga Kasap
{"title":"Tears on Chest X-Ray in Children: Azygos Lobe","authors":"Tolga Kasap","doi":"10.32474/papn.2023.04.000194","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000194","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134972985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-22DOI: 10.32474/papn.2023.04.000183
Genelynne J Beley
{"title":"A Neonate With Complete Congenital Heart Block Delivered Via Ex Utero Intrapartum Treatment (Exit) Procedure: A Case Report","authors":"Genelynne J Beley","doi":"10.32474/papn.2023.04.000183","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000183","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-11DOI: 10.32474/papn.2023.04.000181
Patankar Jahoorahmad Z
Urinary tract infection (UTI) is by far the most common serious bacterial infection in febrile young infants.[1] 99mTc- DMSA scintigraphy is superior to ultrasonography in detecting cortical scars, although the later identifies dilatation of the collecting systems and renal swelling.
{"title":"Value of Cortical Scintigraphy with Technetium-99m Dimercaptosuccinic Acid (99mtc Dmsa) in Children with Acute Urinary Tract Infections","authors":"Patankar Jahoorahmad Z","doi":"10.32474/papn.2023.04.000181","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000181","url":null,"abstract":"Urinary tract infection (UTI) is by far the most common serious bacterial infection in febrile young infants.[1] 99mTc- DMSA scintigraphy is superior to ultrasonography in detecting cortical scars, although the later identifies dilatation of the collecting systems and renal swelling.","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"167 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136212461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-09DOI: 10.32474/papn.2023.04.000179
N Laizer
{"title":"11 Cases of H-Type Tracheoesophageal Fistula: How Diagnosis and Treatment May Be Improved","authors":"N Laizer","doi":"10.32474/papn.2023.04.000179","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000179","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135063865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-06DOI: 10.32474/papn.2023.04.000178
Patankar Jahoorahmad Z
{"title":"A Retrospective Review of Acute Scrotum in Pediatric Patients with Epididymo-Orchitis, Testicular Torsion, and Torsion of Testicular Appendages","authors":"Patankar Jahoorahmad Z","doi":"10.32474/papn.2023.04.000178","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000178","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135322931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-05DOI: 10.32474/papn.2023.04.000176
Sandeep A Tilwani
{"title":"A Qualitative Analysis of Knowledge, Perception and Practices related to Human Milk Banking among Staff Nurses and Lactating mothers, in a tertiary care hospital in South India","authors":"Sandeep A Tilwani","doi":"10.32474/papn.2023.04.000176","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000176","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135406225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-05DOI: 10.32474/papn.2023.04.000177
Patankar Jahoorahmad Z
{"title":"Empyema Thoracis in Children – Tailored Surgical Therapy for Late Referrals: A Single Unit Experience – Study in Suburban Mumbai","authors":"Patankar Jahoorahmad Z","doi":"10.32474/papn.2023.04.000177","DOIUrl":"https://doi.org/10.32474/papn.2023.04.000177","url":null,"abstract":"","PeriodicalId":500873,"journal":{"name":"Progressing aspects in pediatrics and neonatology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135406224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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