Pub Date : 2024-05-31DOI: 10.1101/2024.05.29.24308135
Jason Semprini
Background In the United States, pharyngeal cancer has become the most common type of head and neck cancer, with 80% of cases found in males. Although disparities in treatment delays have been observed in pharyngeal patients, less is known about how policies facilitate timely care. This study aimed to estimate the association between Medicaid expansion and delaying initiation of pharyngeal cancer treatment.
{"title":"Sex and Marital-Status Differences in Delayed Initiation for Pharyngeal Cancer Treatment, Before and After Medicaid Expansion","authors":"Jason Semprini","doi":"10.1101/2024.05.29.24308135","DOIUrl":"https://doi.org/10.1101/2024.05.29.24308135","url":null,"abstract":"<strong>Background</strong> In the United States, pharyngeal cancer has become the most common type of head and neck cancer, with 80% of cases found in males. Although disparities in treatment delays have been observed in pharyngeal patients, less is known about how policies facilitate timely care. This study aimed to estimate the association between Medicaid expansion and delaying initiation of pharyngeal cancer treatment.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141251853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-29DOI: 10.1101/2024.05.28.24308086
Juan David Villalobos Ibarra, Jorge Carrizosa, Andrea Vargas, Carlos Martinez, Denise Battaglini, Daniel Agustin Godoy
Introduction The incidence of stroke mimic symptoms is around 30%. These symptoms impact healthcare costs, often leading mimic stroke patients to undergo unnecessary clinical tests, imaging, and treatments.
{"title":"Analysis of Costs and Diagnostic Experience of Stroke Mimics at a Latin American University Hospital","authors":"Juan David Villalobos Ibarra, Jorge Carrizosa, Andrea Vargas, Carlos Martinez, Denise Battaglini, Daniel Agustin Godoy","doi":"10.1101/2024.05.28.24308086","DOIUrl":"https://doi.org/10.1101/2024.05.28.24308086","url":null,"abstract":"<strong>Introduction</strong> The incidence of stroke mimic symptoms is around 30%. These symptoms impact healthcare costs, often leading mimic stroke patients to undergo unnecessary clinical tests, imaging, and treatments.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141188559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1101/2024.05.02.24306751
Ahaz T. Kulanga, Gibson E. Kapanda, John A. Bartlett, Charles Muiruri, Stef de Jong
Introduction Research in low- and middle-income countries (LMICs) is challenged with poor investment by both in-country governments and philanthropies. Although research grants cover costs directly associated with specific research projects, they do not fully cover costs that are indirectly attributable to specific projects. The relationship between grant funding and actual cost of paying for such projects at institutions of higher learning (IHL) in LMICs is poorly understood. Our purpose was to evaluate unaccounted costs associated with grants and explore the system level factors that support or hinder the goal of “breaking even”.
{"title":"The cost of sponsored research at institutions of higher learning in low- and middle-income countries: a cross-sectional study","authors":"Ahaz T. Kulanga, Gibson E. Kapanda, John A. Bartlett, Charles Muiruri, Stef de Jong","doi":"10.1101/2024.05.02.24306751","DOIUrl":"https://doi.org/10.1101/2024.05.02.24306751","url":null,"abstract":"<strong>Introduction</strong> Research in low- and middle-income countries (LMICs) is challenged with poor investment by both in-country governments and philanthropies. Although research grants cover costs directly associated with specific research projects, they do not fully cover costs that are indirectly attributable to specific projects. The relationship between grant funding and actual cost of paying for such projects at institutions of higher learning (IHL) in LMICs is poorly understood. Our purpose was to evaluate unaccounted costs associated with grants and explore the system level factors that support or hinder the goal of “breaking even”.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140929548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-27DOI: 10.1101/2024.04.26.24306383
Mitchell L. Doucette, Dipak Hemraj, Emily Fisher, D. Luke Macfarlan
Introduction Recent studies suggest that medical cannabis laws might contribute to a reduction in health insurance costs within the individual health insurance markets at the state level. We investigated the effects of adopting a medical cannabis law on the cost of employer-sponsored health insurance.
{"title":"Measuring the Impact of Medical Cannabis Law Adoption on Employer-sponsored Health Insurance Costs: A Difference-in-Difference analysis, 2003-2022","authors":"Mitchell L. Doucette, Dipak Hemraj, Emily Fisher, D. Luke Macfarlan","doi":"10.1101/2024.04.26.24306383","DOIUrl":"https://doi.org/10.1101/2024.04.26.24306383","url":null,"abstract":"<strong>Introduction</strong> Recent studies suggest that medical cannabis laws might contribute to a reduction in health insurance costs within the individual health insurance markets at the state level. We investigated the effects of adopting a medical cannabis law on the cost of employer-sponsored health insurance.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140839267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.1101/2024.04.24.24306275
Nguyen Hoang Thien Huong, Nguyen Duc Toan, Truong Huu Khanh, Le Quoc Thinh, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Nguyen Thi Kim Thoa, Nguyen Thanh Hung, Du Tuan Quy, C. Louise Thwaites, Sarosh R Irani, Le Van Tan, Hugo C. Turner
Background Encephalitis is a significant global health problem, especially in children. Knowledge of its economic burden is essential for policymakers in prioritizing the development and implementation of interventions but remains limited.
{"title":"A Cost of Illness Analysis of Children with Encephalitis Presenting to A Major Hospital in Vietnam","authors":"Nguyen Hoang Thien Huong, Nguyen Duc Toan, Truong Huu Khanh, Le Quoc Thinh, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Nguyen Thi Kim Thoa, Nguyen Thanh Hung, Du Tuan Quy, C. Louise Thwaites, Sarosh R Irani, Le Van Tan, Hugo C. Turner","doi":"10.1101/2024.04.24.24306275","DOIUrl":"https://doi.org/10.1101/2024.04.24.24306275","url":null,"abstract":"<strong>Background</strong> Encephalitis is a significant global health problem, especially in children. Knowledge of its economic burden is essential for policymakers in prioritizing the development and implementation of interventions but remains limited.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of a Risk-Stratified National Breast Screening Programme in the United Kingdom: An updated cost-effectiveness analysis","authors":"Stuart J Wright, Gabriel Rogers, Ewan Gray, Anna Donten, Lorna McWilliams, David P French, D Gareth Evans, Katherine Payne","doi":"10.1101/2024.04.16.24305897","DOIUrl":"https://doi.org/10.1101/2024.04.16.24305897","url":null,"abstract":"<strong>Study objective</strong> To update a published early economic evaluation of exemplar risk-stratified national breast screening programmes (stratified-NBSP).","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140611956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.1101/2024.04.15.24305866
Jun Soo Lee, Raul Segura Escano, Nicole L. Therrien, Ashutosh Kumar, Ami Bhatt, Lisa M. Pollack, Sandra L. Jackson, Feijun Luo
Background Hypertension affects nearly half of U.S. adults, yet remains inadequately controlled in over three-quarters of these cases. This study aims to assess the association between adherence to antihypertensive medications and total medical costs, health care utilization, and productivity-related outcomes.
{"title":"Antihypertensive Medication Adherence and Medical Costs, Health Care Utilization, and Labor Productivity among Persons with Hypertension","authors":"Jun Soo Lee, Raul Segura Escano, Nicole L. Therrien, Ashutosh Kumar, Ami Bhatt, Lisa M. Pollack, Sandra L. Jackson, Feijun Luo","doi":"10.1101/2024.04.15.24305866","DOIUrl":"https://doi.org/10.1101/2024.04.15.24305866","url":null,"abstract":"<strong>Background</strong> Hypertension affects nearly half of U.S. adults, yet remains inadequately controlled in over three-quarters of these cases. This study aims to assess the association between adherence to antihypertensive medications and total medical costs, health care utilization, and productivity-related outcomes.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140612134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.1101/2024.04.09.24305541
Dylan A Mordaunt
Introduction Labour costs are a key driver of healthcare costs and a key component of economic evaluations in healthcare. We undertook the current study to collect information about workforce costs related to clinical genomic testing in Australia, identifying key components of pay scales and contracts, and incorporating these into a matrix to enable modelling of disaggregated costs.
{"title":"Estimating workforce costs in economic evaluations of genomic testing: Towards a standardised Australian health workforce costing model for comparative health systems research","authors":"Dylan A Mordaunt","doi":"10.1101/2024.04.09.24305541","DOIUrl":"https://doi.org/10.1101/2024.04.09.24305541","url":null,"abstract":"<strong>Introduction</strong> Labour costs are a key driver of healthcare costs and a key component of economic evaluations in healthcare. We undertook the current study to collect information about workforce costs related to clinical genomic testing in Australia, identifying key components of pay scales and contracts, and incorporating these into a matrix to enable modelling of disaggregated costs.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-07DOI: 10.1101/2024.04.05.24305373
Ron Handels, William L. Herring, Sabine Grimm, Anders Sköldunger, Bengt Winblad, Anders Wimo, Linus Jönsson
Objectives Market access and reimbursement decisions for new Alzheimer’s disease (AD) treatments are informed by economic evaluations. An open-source model with intuitive structure for model cross-validation can support the transparency and credibility of such evaluations. We describe the new IPECAD open-source model framework (version 2) for the health-economic evaluation of early AD treatment and use it for cross-validation and addressing uncertainty.
目标 阿尔茨海默病（老年痴呆症）新疗法的市场准入和报销决策均以经济评估为依据。具有直观模型交叉验证结构的开源模型可提高此类评估的透明度和可信度。我们介绍了新的 IPECAD 开源模型框架（第 2 版），该框架适用于早期 AD 治疗的卫生经济评估，并可用于交叉验证和解决不确定性问题。
{"title":"New IPECAD open-source model framework for the health technology assessment of early Alzheimer’s disease treatment: development and use cases","authors":"Ron Handels, William L. Herring, Sabine Grimm, Anders Sköldunger, Bengt Winblad, Anders Wimo, Linus Jönsson","doi":"10.1101/2024.04.05.24305373","DOIUrl":"https://doi.org/10.1101/2024.04.05.24305373","url":null,"abstract":"<strong>Objectives</strong> Market access and reimbursement decisions for new Alzheimer’s disease (AD) treatments are informed by economic evaluations. An open-source model with intuitive structure for model cross-validation can support the transparency and credibility of such evaluations. We describe the new IPECAD open-source model framework (version 2) for the health-economic evaluation of early AD treatment and use it for cross-validation and addressing uncertainty.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-06DOI: 10.1101/2024.04.05.24305378
David Chipanta, Connie Osborne, Julia Bohlius, Ani Shakarishvilia, Silas Amo-Agyei, Alinane Linda Nyondo-Mipando, Janne Anton Markus Estill, Olivia Keiser
Introduction In 2013, the World Health Organization (WHO) issued guidelines for cervical pre-cancer screening. It recommended screening women aged 30–49, and younger women once they tested HIV-positive. Subsequent WHO guidelines recommended screening women living with HIV (WLHIV) starting at age 25. However, the impact of 2013 guidelines and age to start screening on screening has not been studied.
导言 2013 年，世界卫生组织（WHO）发布了宫颈癌前病变筛查指南。该指南建议对 30-49 岁的女性进行筛查，并对 HIV 检测呈阳性的年轻女性进行筛查。随后，世卫组织的指南建议从 25 岁开始对女性艾滋病病毒感染者（WLHIV）进行筛查。然而，2013 年的指南和开始筛查的年龄对筛查的影响尚未进行研究。
{"title":"Impact of the 2013 WHO guidelines for screening and treatment of cervical precancerous lesions on women’s screening rates, by HIV-status, in East and Southern Africa: A regression discontinuity design analysis","authors":"David Chipanta, Connie Osborne, Julia Bohlius, Ani Shakarishvilia, Silas Amo-Agyei, Alinane Linda Nyondo-Mipando, Janne Anton Markus Estill, Olivia Keiser","doi":"10.1101/2024.04.05.24305378","DOIUrl":"https://doi.org/10.1101/2024.04.05.24305378","url":null,"abstract":"<strong>Introduction</strong> In 2013, the World Health Organization (WHO) issued guidelines for cervical pre-cancer screening. It recommended screening women aged 30–49, and younger women once they tested HIV-positive. Subsequent WHO guidelines recommended screening women living with HIV (WLHIV) starting at age 25. However, the impact of 2013 guidelines and age to start screening on screening has not been studied.","PeriodicalId":501072,"journal":{"name":"medRxiv - Health Economics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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