Pub Date : 2024-05-07DOI: 10.1101/2024.05.06.24306601
Dale M Harris, Claire Thwaites, Michelle L Callisaya, Richard Blazé, Meg E Morris
Background Although powerlifting has been shown to increase strength and function in some adults, the safety and feasibility of powerlifting exercises modified for people with early onset Parkinson’s disease is not known.
{"title":"Gym-Based Modified Powerlifting Exercises for People with Early Onset Parkinson’s Disease: Study Protocol","authors":"Dale M Harris, Claire Thwaites, Michelle L Callisaya, Richard Blazé, Meg E Morris","doi":"10.1101/2024.05.06.24306601","DOIUrl":"https://doi.org/10.1101/2024.05.06.24306601","url":null,"abstract":"<strong>Background</strong> Although powerlifting has been shown to increase strength and function in some adults, the safety and feasibility of powerlifting exercises modified for people with early onset Parkinson’s disease is not known.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-06DOI: 10.1101/2024.05.06.24306929
Margaret S. Harrington, Stefania D. F. Di Leo, Courtney A. Hlady, Timothy A. Burkhart
Musculoskeletal modeling is a powerful tool to quantify biomechanical factors typically not feasible to measure in vivo, such as hip contact forces and deep muscle activations. The purposes of this review were to summarize current modeling and simulation methods in structural hip disorder research and evaluate model validation practices and study reproducibility. MEDLINE and Web of Science were searched to identify literature relating to the use of musculoskeletal models to investigate structural hip disorders (i.e., involving a bony abnormality of the pelvis, femur, or both). Forty-seven articles were included for analysis. Studies either compared multiple modeling methods or applied a single modeling workflow to answer a research question. Overall, differences in outputs were shown between generic models scaled to participants’ anthropometrics and models with additional patient-specific geometry; however, generic models were most commonly used in application studies. The 11 studies that assessed model validation used qualitative approaches only. There was also wide variability and under-reporting of data collection, data processing, and modeling methods. Common assumptions made in musculoskeletal modeling during the model development, validation, and movement simulations were identified that are important to consider when evaluating the clinical applicability of modeling predictions in patients with structural hip disorders. Differences between generic and patient-specific model outputs exist; however, whether the patient-specific models are more accurate is still unknown. Increased transparency in reporting of data collection, signal processing, and modeling methods is needed to increase study reproducibility and allow for better assessment of modeling results.
肌肉骨骼建模是一种强大的工具，可量化通常无法在体内测量的生物力学因素，如髋关节接触力和深层肌肉激活。本综述旨在总结当前髋关节结构紊乱研究中的建模和模拟方法，并评估模型验证实践和研究的可重复性。我们检索了 MEDLINE 和 Web of Science，以确定与使用肌肉骨骼模型研究结构性髋关节疾病（即涉及骨盆、股骨或两者的骨骼异常）有关的文献。共纳入 47 篇文章进行分析。这些研究或比较了多种建模方法，或采用单一建模工作流程来回答研究问题。总体而言，按参与者人体测量学比例缩放的通用模型与附加特定患者几何特征的模型在输出结果上存在差异；不过，通用模型在应用研究中最常用。对模型验证进行评估的 11 项研究仅使用了定性方法。在数据收集、数据处理和建模方法方面也存在很大的差异和报告不足。研究发现了肌肉骨骼建模在模型开发、验证和运动模拟过程中的常见假设，这些假设在评估建模预测对髋关节结构性疾病患者的临床适用性时非常重要。通用模型和患者特异性模型的输出结果之间存在差异，但患者特异性模型是否更准确仍是未知数。需要增加数据收集、信号处理和建模方法报告的透明度，以提高研究的可重复性，更好地评估建模结果。
{"title":"Musculoskeletal Modeling and Movement Simulation for Structural Hip Disorder Research: A Scoping Review of Methods and Applications","authors":"Margaret S. Harrington, Stefania D. F. Di Leo, Courtney A. Hlady, Timothy A. Burkhart","doi":"10.1101/2024.05.06.24306929","DOIUrl":"https://doi.org/10.1101/2024.05.06.24306929","url":null,"abstract":"Musculoskeletal modeling is a powerful tool to quantify biomechanical factors typically not feasible to measure <em>in vivo,</em> such as hip contact forces and deep muscle activations. The purposes of this review were to summarize current modeling and simulation methods in structural hip disorder research and evaluate model validation practices and study reproducibility. MEDLINE and Web of Science were searched to identify literature relating to the use of musculoskeletal models to investigate structural hip disorders (i.e., involving a bony abnormality of the pelvis, femur, or both). Forty-seven articles were included for analysis. Studies either compared multiple modeling methods or applied a single modeling workflow to answer a research question. Overall, differences in outputs were shown between generic models scaled to participants’ anthropometrics and models with additional patient-specific geometry; however, generic models were most commonly used in application studies. The 11 studies that assessed model validation used qualitative approaches only. There was also wide variability and under-reporting of data collection, data processing, and modeling methods. Common assumptions made in musculoskeletal modeling during the model development, validation, and movement simulations were identified that are important to consider when evaluating the clinical applicability of modeling predictions in patients with structural hip disorders. Differences between generic and patient-specific model outputs exist; however, whether the patient-specific models are more accurate is still unknown. Increased transparency in reporting of data collection, signal processing, and modeling methods is needed to increase study reproducibility and allow for better assessment of modeling results.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.1101/2024.05.03.24306841
Margaret A. French, Paul Hartman, Heather A. Hayes, Leah Ling, John Magel, Anne Thackeray
Background High-value care aims to enhance meaningful patient outcomes while reducing costs. Curating data across healthcare systems with common data models (CDMs) would help these systems move towards high-value healthcare. However, meaningful patient outcomes, such as function, must be represented in commonly used CDMs, such as Observational Medical Outcomes Partnership Model (OMOP). Yet the extent that functional assessments are included in the OMOP CDM is unclear.
{"title":"Examination of the coverage of functional assessments in the OMOP common data model","authors":"Margaret A. French, Paul Hartman, Heather A. Hayes, Leah Ling, John Magel, Anne Thackeray","doi":"10.1101/2024.05.03.24306841","DOIUrl":"https://doi.org/10.1101/2024.05.03.24306841","url":null,"abstract":"<strong>Background</strong> High-value care aims to enhance meaningful patient outcomes while reducing costs. Curating data across healthcare systems with common data models (CDMs) would help these systems move towards high-value healthcare. However, meaningful patient outcomes, such as function, must be represented in commonly used CDMs, such as Observational Medical Outcomes Partnership Model (OMOP). Yet the extent that functional assessments are included in the OMOP CDM is unclear.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"294 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-04DOI: 10.1101/2024.05.03.24306686
Rabi’u Ibrahim, Conran Joseph, Aimée Stewart, Isa Usman Lawal
Background More than half of stroke survivors in LMICs lack access to stroke rehabilitation services. The promotion of self-rehabilitation could be promising in an attempt to address the stroke rehabilitation inadequacies in LMICs. Self-rehabilitation interventions can easily be accepted by many community-dwelling stroke survivors, and therefore, have the potential to drive towards the successful realization of Sustainable Development Goals and other WHO rehabilitation goals. We report a consensus building process that sought to identify which task training is relevant to include in a task-specific self-rehabilitation strategy for the rural community-dwelling stroke survivors.
{"title":"Self-Rehabilitation Strategy for Rural Community-dwelling Stroke Survivors in a Lower-Middle Income Country: A Delphi Study","authors":"Rabi’u Ibrahim, Conran Joseph, Aimée Stewart, Isa Usman Lawal","doi":"10.1101/2024.05.03.24306686","DOIUrl":"https://doi.org/10.1101/2024.05.03.24306686","url":null,"abstract":"<strong>Background</strong> More than half of stroke survivors in LMICs lack access to stroke rehabilitation services. The promotion of self-rehabilitation could be promising in an attempt to address the stroke rehabilitation inadequacies in LMICs. Self-rehabilitation interventions can easily be accepted by many community-dwelling stroke survivors, and therefore, have the potential to drive towards the successful realization of Sustainable Development Goals and other WHO rehabilitation goals. We report a consensus building process that sought to identify which task training is relevant to include in a task-specific self-rehabilitation strategy for the rural community-dwelling stroke survivors.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1101/2024.05.01.24306712
Ata Farajzadeh, Alexe Hébert, Ian M. Lahart, Martin Bilodeau, Matthieu P. Boisgontier
Background Patient motivation is essential for the success of their rehabilitation. Apathy, a state of primary motivational deficiency, may therefore hinder physiotherapists’ interventions, such as those aimed at increasing patients’ physical activity. This study aims to examine the negative relationship between apathy and physical activity and to identify the factors that influence this relationship.
{"title":"Apathy and Physical Activity: A Systematic Review and Meta-Analysis","authors":"Ata Farajzadeh, Alexe Hébert, Ian M. Lahart, Martin Bilodeau, Matthieu P. Boisgontier","doi":"10.1101/2024.05.01.24306712","DOIUrl":"https://doi.org/10.1101/2024.05.01.24306712","url":null,"abstract":"<strong>Background</strong> Patient motivation is essential for the success of their rehabilitation. Apathy, a state of primary motivational deficiency, may therefore hinder physiotherapists’ interventions, such as those aimed at increasing patients’ physical activity. This study aims to examine the negative relationship between apathy and physical activity and to identify the factors that influence this relationship.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1101/2024.05.02.24306772
Jennifer Dens Higano, Kathryn Burns, Geoffrey Smith, Ryan Solinsky
Introduction Individuals with spinal cord injury (SCI) commonly have autonomic dysreflexia (AD) with increased sympathetic activity. After SCI, individuals have decreased baroreflex sensitivity and increased vascular responsiveness.
{"title":"Why do different people with Spinal Cord Injury have differing severity of symptoms with Autonomic Dysreflexia? Exploring relationships of vascular alpha-1 adrenoreceptor and baroreflex sensitivity after SCI","authors":"Jennifer Dens Higano, Kathryn Burns, Geoffrey Smith, Ryan Solinsky","doi":"10.1101/2024.05.02.24306772","DOIUrl":"https://doi.org/10.1101/2024.05.02.24306772","url":null,"abstract":"<strong>Introduction</strong> Individuals with spinal cord injury (SCI) commonly have autonomic dysreflexia (AD) with increased sympathetic activity. After SCI, individuals have decreased baroreflex sensitivity and increased vascular responsiveness.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1101/2024.05.02.24306747
Linette Marie Kofod, Ejvind Frausing Hansen, Barbara Cristina Brocki, Morten Tange Kristensen, Nassim Roberts, Elisabeth Westerdahl
Background Minimising hypoxemia during submaximal walking tests has a positive effect on exercise capacity and dyspnea in patients with COPD on long-term oxygen therapy (LTOT). However, the impact of optimising oxygenation during everyday tasks remains unexplored. Therefore, we investigated the effects of maintaining a target saturation on activities of daily living (ADL) using automated oxygen titration compared to conventional fixed oxygen flow.
{"title":"Optimised oxygenation improves functional capacity during daily activities in patients with COPD on long-term oxygen therapy – a randomised crossover trial","authors":"Linette Marie Kofod, Ejvind Frausing Hansen, Barbara Cristina Brocki, Morten Tange Kristensen, Nassim Roberts, Elisabeth Westerdahl","doi":"10.1101/2024.05.02.24306747","DOIUrl":"https://doi.org/10.1101/2024.05.02.24306747","url":null,"abstract":"<strong>Background</strong> Minimising hypoxemia during submaximal walking tests has a positive effect on exercise capacity and dyspnea in patients with COPD on long-term oxygen therapy (LTOT). However, the impact of optimising oxygenation during everyday tasks remains unexplored. Therefore, we investigated the effects of maintaining a target saturation on activities of daily living (ADL) using automated oxygen titration compared to conventional fixed oxygen flow.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective The objective of this scoping review is to understand the extent and type of evidence available on the correlation between pelvic and lumbar region dysfunction in adult non-surgical patients.
目标 本范围界定综述旨在了解成年非手术患者骨盆和腰椎区域功能障碍之间相关性的现有证据范围和类型。
{"title":"The correlation between lumbar and pelvic dysfunctions in non-post-surgical adult patients: a scoping review protocol","authors":"Tiziana Manni, Francesca Coaro, Monica Nativo, Marina Stocco","doi":"10.1101/2024.05.02.24305675","DOIUrl":"https://doi.org/10.1101/2024.05.02.24305675","url":null,"abstract":"<strong>Objective</strong> The objective of this scoping review is to understand the extent and type of evidence available on the correlation between pelvic and lumbar region dysfunction in adult non-surgical patients.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-02DOI: 10.1101/2024.04.29.24306591
Guilherme Veiga Guimarães, Paulo Roberto Chizzola, Veridiana Moraes D’Avila, Paulo Roberto Santo-Silva, Raphaela Villar Grohes Miranda, Leandro Silva Alves, Edimar Alcides Bocchi
Background Atrial fibrillation (AF) may be linked to cognitive impairment in heart failure (HF) patients. Regular exercise training has numerous benefits, including improving adults’ overall health and cognitive function. However, the effects of exercise training on cognitive function in heart failure patients with reduced ejection fraction and permanent atrial fibrillation (HFAF) are not well understood.
{"title":"Exercise Training Improves Cognitive Function and Neurovascular Control in Patients With Heart Failure and Atrial Fibrillation: A Randomized Clinical Trial","authors":"Guilherme Veiga Guimarães, Paulo Roberto Chizzola, Veridiana Moraes D’Avila, Paulo Roberto Santo-Silva, Raphaela Villar Grohes Miranda, Leandro Silva Alves, Edimar Alcides Bocchi","doi":"10.1101/2024.04.29.24306591","DOIUrl":"https://doi.org/10.1101/2024.04.29.24306591","url":null,"abstract":"<strong>Background</strong> Atrial fibrillation (AF) may be linked to cognitive impairment in heart failure (HF) patients. Regular exercise training has numerous benefits, including improving adults’ overall health and cognitive function. However, the effects of exercise training on cognitive function in heart failure patients with reduced ejection fraction and permanent atrial fibrillation (HFAF) are not well understood.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1101/2024.04.30.24306653
Bin Hu, Doreen Amini, Izma Ghani, Abdul-Samad Ahmed, Shahryar Wasif, Taylor Chomiak
The assessment of physical ability is a critical component in developing personalized exercise prescriptions, monitoring disease progression, and evaluating intervention outcomes across various clinical and general populations. This study evaluates how objective physical performance parameters, measured during a stepping in place (SIP) exercise via Ambulosono wearable system, relate to subjective perceptions of fatigue and breathlessness using Borg and Fatigue Scores. Our overall results show that SIP, as a convenient and simple exercise modality, can be used to rank a user’s physical ability level based on both objective and subjective parameters. Furthermore, while the objective walking/gait parameters may have some predictive ability for the such parameter as cadence, they do not appear to significantly predict the subjective fatigue or breathlessness scores, either before or after the activity. This lack of significant relationships suggests that factors other than the measured objective gait metrics may play a more important role in determining subjective experiences of fatigue and breathlessness during the stepping exercise.
{"title":"Stepping in Place (SIP) as a Novel Physical Ability Assessment in Neurorehabilitation: A Wearable Device-based Validation Study","authors":"Bin Hu, Doreen Amini, Izma Ghani, Abdul-Samad Ahmed, Shahryar Wasif, Taylor Chomiak","doi":"10.1101/2024.04.30.24306653","DOIUrl":"https://doi.org/10.1101/2024.04.30.24306653","url":null,"abstract":"The assessment of physical ability is a critical component in developing personalized exercise prescriptions, monitoring disease progression, and evaluating intervention outcomes across various clinical and general populations. This study evaluates how objective physical performance parameters, measured during a stepping in place (SIP) exercise via Ambulosono wearable system, relate to subjective perceptions of fatigue and breathlessness using Borg and Fatigue Scores. Our overall results show that SIP, as a convenient and simple exercise modality, can be used to rank a user’s physical ability level based on both objective and subjective parameters. Furthermore, while the objective walking/gait parameters may have some predictive ability for the such parameter as cadence, they do not appear to significantly predict the subjective fatigue or breathlessness scores, either before or after the activity. This lack of significant relationships suggests that factors other than the measured objective gait metrics may play a more important role in determining subjective experiences of fatigue and breathlessness during the stepping exercise.","PeriodicalId":501453,"journal":{"name":"medRxiv - Rehabilitation Medicine and Physical Therapy","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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