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Analysis of suspected adverse reactions to food supplements containing beehive products: an update from the Italian Phytovigilance System. 含有蜂产品的食品补充剂的可疑不良反应分析:意大利植物警戒系统的最新情况。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_08
Ilaria Ippoliti, Silvia Di Giacomo, Gabriela Mazzanti, Marco Silano, Francesca Menniti-Ippolito

Introduction: Beehive products are widely used in food supplements; however, their composition variability and allergenic components have raised some concerns. This work aims to provide information about the beehive products safety profile by evaluating the suspected adverse reactions (ARs).

Methods: The suspected report of ARs collected within the Italian Phytovigilance System (IPS) were evaluated. The clinical and demographic characteristics of the cases were described, and the causality assessment performed.

Results: 61 reports were analysed, mainly concerned women. Serious events were reported in 17 forms (28%). The ARs (n=116) referred to respiratory (25.0%), skin (24.1%), and gastrointestinal disorders (21.5%). Label warnings for atopic subjects were present only in 7 food supplements. The causality assessment was mostly probable (54.1%).

Conclusions: Present findings outline relevant information about the safety issues of beehive product consumption, especially in atopic or allergic subjects, and strengthen the importance of IPS to point out safety signals.

导言:蜂产品被广泛应用于食品补充剂中,但其成分变化和过敏原成分引起了一些关注。这项工作旨在通过评估疑似不良反应(ARs),提供有关蜂产品安全性的信息:方法:对意大利植物警戒系统(IPS)收集的疑似 ARs 报告进行了评估。方法:对意大利植物警戒系统(IPS)中收集的疑似不良反应报告进行评估,描述病例的临床和人口特征,并进行因果关系评估:结果:分析了 61 份报告,主要涉及女性。有 17 份(28%)报告了严重事件。ARs(n=116)涉及呼吸系统疾病(25.0%)、皮肤疾病(24.1%)和胃肠道疾病(21.5%)。仅有 7 种食品补充剂针对特应性受试者发布了标签警告。因果关系评估大多为可能(54.1%):目前的研究结果概述了蜂产品食用安全问题的相关信息,特别是对特应性或过敏性受试者,并加强了 IPS 指出安全信号的重要性。
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引用次数: 0
COVID-19 in meat plants: a survey framed within a Target Prevention Plan, in Italy. 肉类加工厂中的 COVID-19:意大利目标预防计划中的一项调查。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_01
Giorgio Di Leone, Luigi Bertinato, Gianfranco Brambilla, Valerio Manno, Flavio Napolano, Simona Savi, Gaetano Settimo, Domenico Lagravinese

Background: During the COVID-19 pandemic, several outbreaks have been recorded worldwide in industrial slaughterhouses and meat-processing plants. Competent Italian health authorities at regional and provincial levels agreed on a risk-oriented control plan.

Methods: Advocacy actions were activated, targeting meat plant managers and related food business operators. A questionnaire focused on the inventoried risk factors from literature was developed and administered voluntarily to interested stakeholders. In addition, an outbreak questionnaire was proposed to the prevention department of local health units.

Results: From 2021 to 2022, 333 advocacy and 24 outbreak questionnaires on 4,765 inventoried plants were collected. The lack of awareness in updating the Risk Assessment Document for COVID-19, non-instrumental body temperature checks at the entrance, working force from different subcontractors, poor hygiene in shared places, and insufficient ventilation were the main critical points recorded.

Conclusions: Results provide a post hoc review with an eye toward future zoonotic pandemics.

背景:在 COVID-19 大流行期间,世界各地的工业屠宰场和肉类加工厂爆发了多起疫情。意大利地区和省级卫生主管部门商定了以风险为导向的控制计划:方法:针对肉类加工厂经理和相关食品企业经营者开展宣传活动。针对文献中列出的风险因素编制了一份调查问卷,并由感兴趣的利益相关者自愿填写。此外,还向地方卫生单位的预防部门提出了一份疫情调查问卷:结果:从 2021 年到 2022 年,共收集了 333 份宣传问卷和 24 份疫情调查问卷,涉及 4765 种库存植物。缺乏更新 COVID-19 风险评估文件的意识、入口处无仪器体温检测、来自不同分包商的劳动力、共用场所卫生条件差以及通风不足是记录的主要关键点:研究结果提供了一份着眼于未来人畜共患病大流行的事后审查报告。
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引用次数: 0
Use of antidepressant and antipsychotic drugs in subjects with hemophilia of the Umbria Region in the period 2011-2022. 2011-2022 年期间翁布里亚大区血友病患者抗抑郁和抗精神病药物的使用情况。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_06
Giuseppe Marano, Romano Arcieri, Rosalba Elisabetta Rocchi, Arianna Annunziata, Maria Cutillo, Giampaolo Bucaneve, Roberto Da Cas, Mariangela Rossi

Introduction: Chronic diseases, such as hemophilia, can evoke psychological sequelae and be associated with a higher risk of mental health disorders. The utilization of antidepressant and antipsychotic drugs in subjects with hemophilia is not completely understood and few data are available.

Objectives: The aim of this analysis is to describe use of antidepressant and antipsychotic drugs in subjects with hemophilia of the Umbria Region in the period 2011-2022.

Methods: A descriptive, cross-sectional, and retrospective analysis based on data on filled prescriptions for antidepressants and antipsychotics has been carried out. The overall and annual prevalence of drugs use and consumption were calculated based on pharmaceutical prescriptions charged to the National Health Service in subjects with hemophilia and matched controls from general population.

Results: In the study period 170 subjects with hemophilia were identified; about 80% were male. About 20% and 8.2% received antidepressants and antipsychotics, respectively. A higher percentage of users and consumption were found in subjects with hemophilia compared to matched controls, although no statistically significant differences were observed.

Conclusions: Our analysis suggests that depression and psychosis are important comorbidities in subjects with hemophilia. Further larger studies are needed in order to confirm these data and better define the burden of mental health disorders in subjects with hemophilia.

导言:血友病等慢性疾病会引发心理后遗症,并与较高的精神疾病风险相关联。血友病患者对抗抑郁药和抗精神病药的使用情况尚不完全清楚,可获得的数据也很少:本分析旨在描述 2011-2022 年间翁布里亚大区血友病患者使用抗抑郁和抗精神病药物的情况:根据已开具的抗抑郁药和抗精神病药处方数据,进行了描述性、横断面和回顾性分析。结果:在研究期间,有 170 名血友病患者使用了抗抑郁剂和抗精神病药物:在研究期间,共发现了 170 名血友病患者,其中约 80% 为男性。约 20% 和 8.2% 的患者分别服用了抗抑郁药和抗精神病药。与匹配的对照组相比,血友病患者使用和服用抗抑郁药的比例较高,但在统计学上未发现显著差异:我们的分析表明,抑郁症和精神病是血友病患者的重要合并症。我们的分析表明,抑郁症和精神病是血友病患者的重要合并症,需要进一步开展更大规模的研究,以确认这些数据,并更好地界定血友病患者的精神疾病负担。
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引用次数: 0
Precision prevention network: new pathway for supporting women victims of violence. 精准预防网络:支持暴力受害妇女的新途径。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_09
Anna Carannante, Marco Giustini, Emanuele Caredda, Simona Gaudi

Introduction: Violence against women (VAW) is a persistent global public health problem that runs across all social classes and ethnicities with a considerable negative influence on women's health and behaviour. Early detection, appropriate interventions and multidisciplinary cooperation are crucial factors in tackling gender violence.

Objectives: This note describes "The Violence against women: long-term health effects for precision prevention" transdisciplinary and multicenter project that aims to implement the National Guidelines with two sets of questions: the European Injury Database (EU-IDB) violence module and the Post-Traumatic Stress Disorder (PTSD) questionnaire for improving innovative approaches to limit the long-term health effect of VAW. Furthermore, the analysis of epigenetic profile in women's DNA may contribute to the knowledge of molecular mechanisms underlying PTSD and other non-communicable diseases. Epigenomic research in parallel with rigourous guidelines and social, educational, clinical and community interventions could accomplish innovative precision prevention protocols.

Conclusions: Public health plays essential role in identifying risk factors and strengthening the support for women victims of violence.

导言:暴力侵害妇女(VAW)是一个长期存在的全球性公共卫生问题,它横跨各个社会阶层和种族,对妇女的健康和行为产生了相当大的负面影响。早期发现、适当干预和多学科合作是应对性别暴力的关键因素:本说明介绍了 "暴力侵害妇女行为:精准预防的长期健康影响 "跨学科多中心项目,该项目旨在通过两组问题实施《国家指导方针》:欧洲伤害数据库(EU-IDB)暴力模块和创伤后应激障碍(PTSD)问卷,以改进创新方法,限制暴力侵害妇女行为对健康的长期影响。此外,对妇女 DNA 表观遗传特征的分析可能有助于了解创伤后应激障碍和其他非传染性疾病的分子机制。表观基因组研究与严格的指导方针以及社会、教育、临床和社区干预措施并行,可以实现创新的精准预防方案:公共卫生在确定风险因素和加强对暴力受害妇女的支持方面发挥着至关重要的作用。
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引用次数: 0
Clinical medical practice and stigma towards patients with substance use disorder in an Italian sample of healthcare workers. 意大利医护人员的临床医疗实践与对药物使用障碍患者的羞辱。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_05
Alice Valdesalici, Diego Saccon, Elena Boatto, Amalia Manzan, Roberto Manera, Alessandro Pani, Valentina Pavani, Giancarlo Zecchinato, Vito Sava, Giovanni Greco, Sally Paganin, Marco Solmi

Introduction: People with substance use disorder (SUD) face challenges like stigma and discrimination, impacting their healthcare experiences.

Aim: This study aims to: (i) assess physicians' clinical practices and stigma toward SUD patients among healthcare personnel and (ii) explore the relationship among stigma, psychological well-being, and burnout.

Methods: A survey covering sociodemographic data, physicians' clinical practices, stigmatizing attitudes, psychological well-being, and burnout was completed by 1,796 employees of the Veneto's Local Health Units (Italy).

Results: Healthcare professionals reported increased stigma towards SUDs (p-values<0.05). Stigma consistently correlated with variables such as sex, profession, department, and levels of burnout (p-values<0.05). Notably, high burnout levels were associated with increased stigma. Staff in addiction departments displayed lower stigma levels compared to other departments. No significant differences were found in physicians' clinical practices.

Conclusions: Targeted training for healthcare professionals is crucial to reduce stigma, enhance attitudes toward SUDs, and broaden overall knowledge of the condition.

简介本研究旨在:(i) 评估医生的临床实践和医护人员对 SUD 患者的污名化态度;(ii) 探讨污名化、心理健康和职业倦怠之间的关系:威尼托地方卫生单位(意大利)的 1796 名员工完成了一项调查,内容包括社会人口学数据、医生的临床实践、污名化态度、心理健康和职业倦怠:结果:医护人员对药物依赖性疾病的鄙视程度有所上升(p 值):结论:对医疗保健专业人员进行有针对性的培训对于减少耻辱感、改善对药物依赖性障碍的态度以及扩大对该疾病的总体了解至关重要。
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引用次数: 0
Changes in the use of nicotine-containing products during and after the COVID-19 pandemic in a representative sample of the Italian adult population. 在 COVID-19 大流行期间和之后,意大利成年人口代表性样本中含尼古丁产品使用情况的变化。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_03
Margherita Zeduri, Cosimo Campagni, Giulia Carreras, Silvano Gallus, Alessandra Lugo, Chiara Stival, Luisa Mastrobattista, Claudia Mortali, Anna Odone, Andrea Amerio, Giuseppe Gorini

Introduction: To assess nicotine-containing products (NCPs; heated tobacco products and/or electronic cigarettes) use in relation to conventional smoking.

Methods: "LOST IN ITALY" ("LOckdown and Lifestyles IN ITALY") and "LOST IN TOSCANA" cross-sectional surveys estimated lifestyles changes before, during, and after the lockdown in a representative sample of the Italian population. A Poisson regression model was used to estimate prevalence ratios of NCP use according to socio-demographic, mental distress, and smoking variables.

Results: The prevalence of conventional cigarette smokers did not decrease, remaining stable at 23%. Exclusive conventional cigarette smokers decreased from 21% before the lockdown in 2020 to 15% in 2023 but dual users, representing the large majority of NCP users, increased by 4 times, and exclusive NCP users decreased from 7% in 2020 to 5% in 2023.

Conclusions: NCPs are mostly accompanying instead of replacing conventional cigarettes. A targeted campaign should be developed in Italy to raise awareness on that.

简介:目的:评估含尼古丁产品(NCP;加热烟草制品和/或电子香烟)的使用与传统吸烟的关系:评估含尼古丁产品(NCP;加热烟草制品和/或电子香烟)的使用与传统吸烟的关系:"LOST IN ITALY"("意大利封锁与生活方式")和 "LOST IN TOSCANA "横断面调查估计了意大利人口代表性样本在封锁前、封锁期间和封锁后的生活方式变化。采用泊松回归模型,根据社会人口、精神痛苦和吸烟等变量,估算出使用非氯丙烷的流行率:结果:传统香烟吸烟者的流行率没有下降,稳定在 23%。只吸食传统香烟的吸烟者从 2020 年封锁前的 21% 降至 2023 年的 15%,但占非传染性疾病使用者绝大多数的双重使用者增加了 4 倍,只吸食非传染性疾病的使用者从 2020 年的 7% 降至 2023 年的 5%:结论:非混合型卷烟主要是伴随而非取代传统卷烟。意大利应开展有针对性的宣传活动,提高人们对此的认识。
{"title":"Changes in the use of nicotine-containing products during and after the COVID-19 pandemic in a representative sample of the Italian adult population.","authors":"Margherita Zeduri, Cosimo Campagni, Giulia Carreras, Silvano Gallus, Alessandra Lugo, Chiara Stival, Luisa Mastrobattista, Claudia Mortali, Anna Odone, Andrea Amerio, Giuseppe Gorini","doi":"10.4415/ANN_24_03_03","DOIUrl":"https://doi.org/10.4415/ANN_24_03_03","url":null,"abstract":"<p><strong>Introduction: </strong>To assess nicotine-containing products (NCPs; heated tobacco products and/or electronic cigarettes) use in relation to conventional smoking.</p><p><strong>Methods: </strong>\"LOST IN ITALY\" (\"LOckdown and Lifestyles IN ITALY\") and \"LOST IN TOSCANA\" cross-sectional surveys estimated lifestyles changes before, during, and after the lockdown in a representative sample of the Italian population. A Poisson regression model was used to estimate prevalence ratios of NCP use according to socio-demographic, mental distress, and smoking variables.</p><p><strong>Results: </strong>The prevalence of conventional cigarette smokers did not decrease, remaining stable at 23%. Exclusive conventional cigarette smokers decreased from 21% before the lockdown in 2020 to 15% in 2023 but dual users, representing the large majority of NCP users, increased by 4 times, and exclusive NCP users decreased from 7% in 2020 to 5% in 2023.</p><p><strong>Conclusions: </strong>NCPs are mostly accompanying instead of replacing conventional cigarettes. A targeted campaign should be developed in Italy to raise awareness on that.</p>","PeriodicalId":502090,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"60 3","pages":"184-190"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Children's diet assessed with the Mediterranean Diet Index: the finding of new eating habits and their impact on a cohort of Italian children. 用地中海饮食指数评估儿童饮食:发现新的饮食习惯及其对一组意大利儿童的影响。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_02
Irene Rutigliano, Morena Luce Mansueto, Rossella Canestrale, Rossella Giorgio, Michele Sacco, Maria Rosa Pastore

Objectives: Mediterranean Diet (MD) has been inversely associated with many diseases: it reduces total mortality and lowers cardiovascular risk. Despite the known benefits of MD, variations of dietary habits have occurred in recent years especially in young people. The aim of our study is to evaluate MD adherence in a cohort of Italian children and adolescents living in Southern Italy.

Methods and results: Adherence to MD was evaluated with the Mediterranean Diet Index (KIDMED). Sex, age, and anthropometric measures were recorded on a population of 132 children; of those 71.2% showed poor adherence to MD, 26.5% average adherence and only 2.3% good adherence. Higher prevalence of poor adherence was recorded in obese children and there was statistically significant inverse correlation between age and adherence score.

Conclusions: Our results highlight low adherence to MD in a cohort of Italian children. These findings support the importance of monitoring dietary habits, especially in adolescents.

目的:地中海饮食(Mediterranean Diet,MD)与多种疾病呈反向关系:它能降低总死亡率并降低心血管风险。尽管地中海饮食的益处众所周知,但近年来饮食习惯发生了变化,尤其是在年轻人中。我们这项研究的目的是评估居住在意大利南部的意大利儿童和青少年群体是否坚持食用 MD:地中海饮食指数(KIDMED)对地中海饮食的坚持情况进行了评估。对 132 名儿童的性别、年龄和人体测量指标进行了记录;其中 71.2% 的儿童对地中海饮食的依从性较差,26.5% 的儿童依从性一般,只有 2.3% 的儿童依从性较好。肥胖儿童的依从性较差,年龄与依从性得分之间存在统计学意义上的显著负相关:我们的研究结果表明,在一组意大利儿童中,MD 的依从性较低。这些结果支持了监测饮食习惯的重要性,尤其是在青少年中。
{"title":"Children's diet assessed with the Mediterranean Diet Index: the finding of new eating habits and their impact on a cohort of Italian children.","authors":"Irene Rutigliano, Morena Luce Mansueto, Rossella Canestrale, Rossella Giorgio, Michele Sacco, Maria Rosa Pastore","doi":"10.4415/ANN_24_03_02","DOIUrl":"https://doi.org/10.4415/ANN_24_03_02","url":null,"abstract":"<p><strong>Objectives: </strong>Mediterranean Diet (MD) has been inversely associated with many diseases: it reduces total mortality and lowers cardiovascular risk. Despite the known benefits of MD, variations of dietary habits have occurred in recent years especially in young people. The aim of our study is to evaluate MD adherence in a cohort of Italian children and adolescents living in Southern Italy.</p><p><strong>Methods and results: </strong>Adherence to MD was evaluated with the Mediterranean Diet Index (KIDMED). Sex, age, and anthropometric measures were recorded on a population of 132 children; of those 71.2% showed poor adherence to MD, 26.5% average adherence and only 2.3% good adherence. Higher prevalence of poor adherence was recorded in obese children and there was statistically significant inverse correlation between age and adherence score.</p><p><strong>Conclusions: </strong>Our results highlight low adherence to MD in a cohort of Italian children. These findings support the importance of monitoring dietary habits, especially in adolescents.</p>","PeriodicalId":502090,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"60 3","pages":"179-183"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Responding to healthcare needs of different religious communities: implications for the Italian National Health Service. 满足不同宗教团体的医疗需求:对意大利国家医疗服务的影响。
Pub Date : 2024-07-01 DOI: 10.4415/ANN_24_03_07
Claudio Giovannini, Leuconoe Grazia Sisti, Paola Gabbrielli, Cesare Marino, Claudio Pacillo, Angelo Farina, Maria Angela Falà, Walter Malorni

Background: One of the challenges that our Italian National Health Service is facing is the structural change of society, regarding the migratory flows recorded in the last thirty years with the consequent increase in faithful who follow religions other than the Catholic one.

Aim of the study: This study highlights the critical issues due to religious indications of different faiths which can have implications for our healthcare system. The study analyses the different concept of health, illness, well-being and pain, life and death, gender issues, rules regarding diet, fasting and drugs that can be taken by the patients. Religious norms regarding procreation, termination of pregnancy, and the use of contraceptive methods are also considered; as well as euthanasia, organ donation and the specific needs for end-of-life rites in different religious faiths, as they are presented in the literature and as they emerged in the dialogue with the national representatives of the religious faiths that make up the Interreligious Table of Rome. Conclusions and future perspective. The complexity of this relatively recent Italian reality necessarily leads to an in-depth analysis of religious and cultural diversity. The National Health Service must face a series of changes which concern both the adaptation of health structures and the adequate preparation of health workers, who are called upon to know how to communicate and offer care and assistance to all.

背景:意大利国家医疗服务面临的挑战之一是社会结构的变化,这与过去三十年中记录的移民潮有关,随之而来的是信奉天主教以外宗教的信徒的增加:本研究强调了由于不同信仰的宗教迹象而产生的关键问题,这些问题可能会对我们的医疗保健系统产生影响。研究分析了健康、疾病、幸福和痛苦、生与死、性别问题、饮食规则、禁食和病人可以服用的药物等不同的概念。此外,还考虑了关于生育、终止妊娠和使用避孕方法的宗教规范,以及安乐死、器官捐赠和不同宗教信仰对临终仪式的具体需求,这些都是文献中介绍的内容,也是与罗马宗教间会议的宗教信仰国家代表对话时出现的内容。结论和未来展望。意大利近代现实的复杂性必然导致对宗教和文化多样性的深入分析。国家保健服务必须面对一系列变化,这些变化既涉及保健结构的调整,也涉及保健工 作者的充分准备,他们必须懂得如何与所有人沟通并向所有人提供护理和援助。
{"title":"Responding to healthcare needs of different religious communities: implications for the Italian National Health Service.","authors":"Claudio Giovannini, Leuconoe Grazia Sisti, Paola Gabbrielli, Cesare Marino, Claudio Pacillo, Angelo Farina, Maria Angela Falà, Walter Malorni","doi":"10.4415/ANN_24_03_07","DOIUrl":"https://doi.org/10.4415/ANN_24_03_07","url":null,"abstract":"<p><strong>Background: </strong>One of the challenges that our Italian National Health Service is facing is the structural change of society, regarding the migratory flows recorded in the last thirty years with the consequent increase in faithful who follow religions other than the Catholic one.</p><p><strong>Aim of the study: </strong>This study highlights the critical issues due to religious indications of different faiths which can have implications for our healthcare system. The study analyses the different concept of health, illness, well-being and pain, life and death, gender issues, rules regarding diet, fasting and drugs that can be taken by the patients. Religious norms regarding procreation, termination of pregnancy, and the use of contraceptive methods are also considered; as well as euthanasia, organ donation and the specific needs for end-of-life rites in different religious faiths, as they are presented in the literature and as they emerged in the dialogue with the national representatives of the religious faiths that make up the Interreligious Table of Rome. Conclusions and future perspective. The complexity of this relatively recent Italian reality necessarily leads to an in-depth analysis of religious and cultural diversity. The National Health Service must face a series of changes which concern both the adaptation of health structures and the adequate preparation of health workers, who are called upon to know how to communicate and offer care and assistance to all.</p>","PeriodicalId":502090,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"60 3","pages":"216-224"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dangerous exposures to chemicals managed by Poison Centers all around the world during the COVID-19 pandemic: a systematic review and proportional meta-analysis. COVID-19大流行期间世界各地毒物中心管理的化学品危险暴露:系统回顾和比例荟萃分析。
Pub Date : 2024-04-01 DOI: 10.4415/ANN_24_02_08
Lucrezia Lanciotti, Felice Giordano, Rosanna Maria Fidente, Carolina Ferranti, Roberta Lavalle, Marco Famele, Denise Pires Marafon, Rosa Draisci

Introduction: During COVID-19 pandemic, cleaning/disinfection activities were highly recommended. This study summarizes the state of art and estimates the prevalence of dangerous exposures to specific chemicals managed by Poison Centers (PCs) from all over the world during 2020 vs 2019, trying to overcome the critical aspects of the product categorization systems used by PCs.

Materials and methods: A systematic research was conducted in 3 major databases and 2 websites of PCs associations. Proportional meta-analyses were performed to estimate the prevalence of exposures to disinfectants, household products and hand sanitizers in 2020 vs 2019.

Results: The pooled prevalence of exposures to disinfectants, household products and hand sanitizers were respectively 5.9% (95% CI 4.9-7.0) (2019: 4.4% vs 2020: 7.8%; p=0.22), 25.9% (95% CI 24.0-27.7) (2019: 25.0% vs 2020: 28.6%; p=0.71) and 1.6% (95% CI 1.3-1.9) (2019: 0.6% vs 2020: 2.8%; p<0.001).

Conclusions: This study detected overall increases of exposures to specific chemicals in 2020, suggesting that the awareness on topics related to the safe use of these products should be improved, especially during health emergencies, highlighting the need to develop standardized systems to better compare data coming from PCs all over the world.

介绍:在 COVID-19 大流行期间,人们强烈建议开展清洁/消毒活动。本研究总结了最新研究成果,并估算了 2020 年与 2019 年全球中毒中心(PCs)管理的特定化学品的危险接触率,试图克服 PCs 使用的产品分类系统的关键问题:在 3 个主要数据库和 2 个毒物中心协会网站上进行了系统研究。进行了比例荟萃分析,以估计 2020 年与 2019 年接触消毒剂、家用产品和洗手液的流行率:接触消毒剂、家用产品和洗手液的总体流行率分别为5.9%(95% CI 4.9-7.0)(2019年:4.4% vs 2020年:7.8%;p=0.22)、25.9%(95% CI 24.0-27.7)(2019年:25.0% vs 2020年:28.6%;p=0.71)和1.6%(95% CI 1.3-1.9)(2019年:0.6% vs 2020年:2.8%;p结论:这项研究发现,2020 年特定化学品的暴露量总体增加,这表明应提高对安全使用这些产品相关主题的认识,尤其是在卫生紧急情况下,这突出表明有必要开发标准化系统,以更好地比较来自世界各地 PC 的数据。
{"title":"Dangerous exposures to chemicals managed by Poison Centers all around the world during the COVID-19 pandemic: a systematic review and proportional meta-analysis.","authors":"Lucrezia Lanciotti, Felice Giordano, Rosanna Maria Fidente, Carolina Ferranti, Roberta Lavalle, Marco Famele, Denise Pires Marafon, Rosa Draisci","doi":"10.4415/ANN_24_02_08","DOIUrl":"10.4415/ANN_24_02_08","url":null,"abstract":"<p><strong>Introduction: </strong>During COVID-19 pandemic, cleaning/disinfection activities were highly recommended. This study summarizes the state of art and estimates the prevalence of dangerous exposures to specific chemicals managed by Poison Centers (PCs) from all over the world during 2020 vs 2019, trying to overcome the critical aspects of the product categorization systems used by PCs.</p><p><strong>Materials and methods: </strong>A systematic research was conducted in 3 major databases and 2 websites of PCs associations. Proportional meta-analyses were performed to estimate the prevalence of exposures to disinfectants, household products and hand sanitizers in 2020 vs 2019.</p><p><strong>Results: </strong>The pooled prevalence of exposures to disinfectants, household products and hand sanitizers were respectively 5.9% (95% CI 4.9-7.0) (2019: 4.4% vs 2020: 7.8%; p=0.22), 25.9% (95% CI 24.0-27.7) (2019: 25.0% vs 2020: 28.6%; p=0.71) and 1.6% (95% CI 1.3-1.9) (2019: 0.6% vs 2020: 2.8%; p<0.001).</p><p><strong>Conclusions: </strong>This study detected overall increases of exposures to specific chemicals in 2020, suggesting that the awareness on topics related to the safe use of these products should be improved, especially during health emergencies, highlighting the need to develop standardized systems to better compare data coming from PCs all over the world.</p>","PeriodicalId":502090,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"60 2","pages":"134-144"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of out-of-hospital births and perinatal outcomes: data from the Lazio Region, Italy, cross-sectional study from 2019 to 2021. 院外分娩的特点和围产期结果:意大利拉齐奥大区的数据,2019 年至 2021 年横断面研究。
Pub Date : 2024-04-01 DOI: 10.4415/ANN_24_02_03
Roberta Vittoria Cicero, Francesca Zambri, Michele Grandolfo, Federica Varone, Margaret Smith, Sofia Colaceci

Introduction: In Italy, the primary place of birth is typically a hospital, with only a small number of women opting for an out-of-hospital setting. This study details the characteristics of midwifery care and perinatal and maternal outcomes of women who gave birth in an out-of-hospital setting in the Lazio Region, Italy, from 2019 to 2021.

Methods: A cross-sectional study was carried out. The study population included 542 healthy low-risk women who completed the process of planning an out-of-hospital birth, and excluding transfers, this resulted in a total sample of 478 women who gave birth out-of-hospital. Descriptive and inferential analyses and also a logistic regression model were performed.

Results: The main outcomes of the out-of-hospital deliveries were: intact perineum in 38.9% of cases, two cases of 3rd degree laceration (0.4%) and in one case (0.2%) episiotomy. Intrapartum emergencies occurred in 85 out of 478 women (17.8%) but only 10 women required a transfer to hospital after delivery. The one minute Apgar score was equal to or greater than 7 in 99.2% of cases. Exclusive breastfeeding of 96% one week after birth and 94.6% one month. Furthermore, having a previous vaginal hospital birth (adjOR 9.7; CI 95% 4.33-21.68 P<0.001) and a previous out-of-hospital birth (adjOR 24.2; CI 95% 3.23-181.48 P=0.002) was associated with the continuation of out-of-hospital birth.

Conclusions: For low-risk pregnant women who have planned an out-of-hospital birth, it has been shown to be a safe, adequate, appropriate, and effective alternative.

导言:在意大利,主要的分娩场所通常是医院,只有少数产妇选择院外分娩。本研究详细介绍了2019年至2021年意大利拉齐奥大区在院外分娩的产妇的助产护理特点以及围产期和孕产妇结局:方法:开展了一项横断面研究。研究对象包括542名完成院外分娩计划过程的健康低风险产妇,排除转院的产妇后,院外分娩的产妇样本总数为478名。研究人员对样本进行了描述性和推论性分析,并建立了逻辑回归模型:院外分娩的主要结果是:38.9%的产妇会阴完好,两例三度裂伤(0.4%),一例外阴切开术(0.2%)。在 478 名产妇中,有 85 名(17.8%)出现了产中急症,但只有 10 名产妇在分娩后需要转院。99.2% 的产妇一分钟阿普加评分等于或大于 7 分。产后一周纯母乳喂养率为 96%,一个月纯母乳喂养率为 94.6%。此外,曾在医院经阴道分娩(adjOR 9.7; CI 95% 4.33-21.68 PConclusions:对于计划在院外分娩的低风险孕妇来说,院外分娩已被证明是一种安全、充分、适当且有效的选择。
{"title":"Characteristics of out-of-hospital births and perinatal outcomes: data from the Lazio Region, Italy, cross-sectional study from 2019 to 2021.","authors":"Roberta Vittoria Cicero, Francesca Zambri, Michele Grandolfo, Federica Varone, Margaret Smith, Sofia Colaceci","doi":"10.4415/ANN_24_02_03","DOIUrl":"https://doi.org/10.4415/ANN_24_02_03","url":null,"abstract":"<p><strong>Introduction: </strong>In Italy, the primary place of birth is typically a hospital, with only a small number of women opting for an out-of-hospital setting. This study details the characteristics of midwifery care and perinatal and maternal outcomes of women who gave birth in an out-of-hospital setting in the Lazio Region, Italy, from 2019 to 2021.</p><p><strong>Methods: </strong>A cross-sectional study was carried out. The study population included 542 healthy low-risk women who completed the process of planning an out-of-hospital birth, and excluding transfers, this resulted in a total sample of 478 women who gave birth out-of-hospital. Descriptive and inferential analyses and also a logistic regression model were performed.</p><p><strong>Results: </strong>The main outcomes of the out-of-hospital deliveries were: intact perineum in 38.9% of cases, two cases of 3rd degree laceration (0.4%) and in one case (0.2%) episiotomy. Intrapartum emergencies occurred in 85 out of 478 women (17.8%) but only 10 women required a transfer to hospital after delivery. The one minute Apgar score was equal to or greater than 7 in 99.2% of cases. Exclusive breastfeeding of 96% one week after birth and 94.6% one month. Furthermore, having a previous vaginal hospital birth (adjOR 9.7; CI 95% 4.33-21.68 P<0.001) and a previous out-of-hospital birth (adjOR 24.2; CI 95% 3.23-181.48 P=0.002) was associated with the continuation of out-of-hospital birth.</p><p><strong>Conclusions: </strong>For low-risk pregnant women who have planned an out-of-hospital birth, it has been shown to be a safe, adequate, appropriate, and effective alternative.</p>","PeriodicalId":502090,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"60 2","pages":"98-106"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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