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The Japanese journal of antibiotics最新文献

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[Two surgical cases of pulmonary aspergilloma]. [两例肺曲霉瘤手术病例]。
Pub Date : 2001-01-01
M Tajima, T Tsuji, C Hidaka, K Hashimoto, S Mikami, M Baba, S Nakamura, T Iwabuchi, T Yoshimura, M Tanaka
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引用次数: 0
[Case of pulmonary aspergillosis with severe hemoptysis successfully treated by right upper lobectomy following TAE]. [肺曲霉菌病伴严重咯血病例,TAE术后右上肺叶切除术成功治愈]。
Pub Date : 2001-01-01
S Sakamoto, M Kawahata, K Kishi, N Tsuboi, K Narui, S Honnma, R Nakatani, K Nakata, H Tomoyasu, S Tanimura, T Kono, S Tanaka, H Matsushita
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引用次数: 0
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture]. [岐阜县肺炎链球菌菌株的频率和对几种抗生素的敏感性监测]。
Pub Date : 2000-12-01
S Ishigo, T Tamaya, S Matsubara, H Suematsu, H Sawamura, Y Matsukawa, H Hashido, I Iwata, H Mikamo

The frequency and the antibacterial sensitivity of Streptococcus pneumoniae strains isolated from 6 key hospitals (in 5 areas) and 1 otorhinolaryngology clinic in Gifu Prefecture from February to March, 1999, were investigated with several antibiotics. A total of 128 strains of Streptococcus pneumoniae were isolated throughout the study: 47 strains (36.7%) of penicillin-susceptible S. pneumoniae (PSSP), 51 strains (39.8%) of penicillin-intermediate S. pneumoniae (PISP), and 30 strains (23.4%) of penicillin-resistant S. pneumoniae (PRSP); the resistant bacteria being relatively prominent. In these hospitals, PSSP was isolated by 38.8% in all the key hospitals and by 30% in the otolaryngology clinic with almost no discernible difference. PISP was isolated by 63.3%, higher in the otolaryngology clinic and PRSP by 28.6%, higher in the key hospitals conversely. The MIC90s in PISP and PRSP were determined with the antibiotics. In result, only cefditoren (CDTR) showed favorable antibacterial activities with the MIC90 of 0.78 microgram/ml among penicillins or oral cephems. The MIC90s of carbapenems such as imipenem (IPM), meropenem (MEPM), and panipenem (PAPM) were less than 0.39 microgram/ml; particularly, PAPM showed the highest antibacterial activities. Among new quinolones such as tosufloxacin (TFLX), levofloxacin (LVFX), sparfloxacin (SPFX), and ciprofloxacin (CPFX), TFLX showed the highest antibacterial activities with the MIC90 of 0.39 microgram/ml. Other agents showed very low antibacterial activities as the MIC90s were 25 micrograms/ml in minocycline (MINO) and more than 100 micrograms/ml in clarithromycin (CAM) and clindamycin (CLDM).

研究人员使用多种抗生素对 1999 年 2 月至 3 月期间从岐阜县 6 家重点医院(5 个地区)和 1 家耳鼻喉科诊所分离出的肺炎链球菌菌株的频率和抗菌敏感性进行了调查。在整个研究过程中,共分离出 128 株肺炎链球菌:其中 47 株(36.7%)青霉素敏感型肺炎链球菌(PSSP)、51 株(39.8%)青霉素中间型肺炎链球菌(PISP)和 30 株(23.4%)青霉素耐药型肺炎链球菌(PRSP);耐药菌相对较多。在这些医院中,所有重点医院分离出 PSSP 的比例为 38.8%,耳鼻喉科门诊分离出 PSSP 的比例为 30%,几乎没有明显差异。耳鼻喉科诊所分离出的 PISP 占 63.3%,而重点医院分离出的 PRSP 占 28.6%,反之较高。用抗生素测定了 PISP 和 PRSP 的 MIC90。结果显示,在青霉素类或口服头孢菌素中,只有头孢地托伦(CDTR)显示出良好的抗菌活性,其 MIC90 为 0.78 微克/毫升。亚胺培南(IPM)、美罗培南(MEPM)和帕尼培南(PAPM)等碳青霉烯类药物的 MIC90 均小于 0.39 微克/毫升,其中尤以帕尼培南的抗菌活性最高。在托舒沙星(TFLX)、左氧氟沙星(LVFX)、司帕沙星(SPFX)和环丙沙星(CPFX)等新型喹诺酮类药物中,TFLX 的抗菌活性最高,MIC90 为 0.39 微克/毫升。其他药物的抗菌活性很低,米诺环素(MINO)的 MIC90 为 25 微克/毫升,克拉霉素(CAM)和克林霉素(CLDM)的 MIC90 超过 100 微克/毫升。
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引用次数: 0
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The Japanese journal of antibiotics
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