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A multi-criteria approach for selecting an explanation from the set of counterfactuals produced by an ensemble of explainers 从解释者集合产生的反事实集合中选择解释的多标准方法
Pub Date : 2024-03-20 DOI: 10.61822/amcs-2024-0009
Ignacy Stkepka, Mateusz Lango, Jerzy Stefanowski
Counterfactuals are widely used to explain ML model predictions by providing alternative scenarios for obtaining the more desired predictions. They can be generated by a variety of methods that optimize different, sometimes conflicting, quality measures and produce quite different solutions. However, choosing the most appropriate explanation method and one of the generated counterfactuals is not an easy task. Instead of forcing the user to test many different explanation methods and analysing conflicting solutions, in this paper, we propose to use a multi-stage ensemble approach that will select single counterfactual based on the multiple-criteria analysis. It offers a compromise solution that scores well on several popular quality measures. This approach exploits the dominance relation and the ideal point decision aid method, which selects one counterfactual from the Pareto front. The conducted experiments demonstrated that the proposed approach generates fully actionable counterfactuals with attractive compromise values of the considered quality measures.
反事实被广泛用于解释 ML 模型的预测结果,为获得更理想的预测结果提供替代方案。反事实可以通过多种方法生成,这些方法可以优化不同的质量度量,有时甚至是相互冲突的质量度量,并产生截然不同的解决方案。然而,选择最合适的解释方法和生成的反事实之一并非易事。本文建议使用一种多阶段组合方法,在多重标准分析的基础上选择单一的反事实,而不是强迫用户测试多种不同的解释方法并分析相互冲突的解决方案。它提供了一种折中的解决方案,在几种流行的质量衡量标准上得分都很高。该方法利用支配关系和理想点辅助决策方法,从帕累托前沿选择一个反事实。所进行的实验表明,所提出的方法能生成完全可操作的反事实,并在所考虑的质量衡量标准方面具有有吸引力的折衷值。
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引用次数: 0
Assessment Measures of an Ensemble Classifier Based on the Distributivity Equation to Predict the Presence of Severe Coronary Artery Disease 基于分布方程的集合分类器预测严重冠状动脉疾病的评估措施
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0026
Ewa Rak, A. Szczur, Jan G. Bazan, S. Bazan-Socha
Abstract The aim of this study is to apply and evaluate the usefulness of the hybrid classifier to predict the presence of serious coronary artery disease based on clinical data and 24-hour Holter ECG monitoring. Our approach relies on an ensemble classifier applying the distributivity equation aggregating base classifiers accordingly. Such a method may be helpful for physicians in the management of patients with coronary artery disease, in particular in the face of limited access to invasive diagnostic tests, i.e., coronary angiography, or in the case of contraindications to its performance. The paper includes results of experiments performed on medical data obtained from the Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland. The data set contains clinical data, data from Holter ECG (24-hour ECG monitoring), and coronary angiography. A leave-one-out cross-validation technique is used for the performance evaluation of the classifiers on a data set using the WEKA (Waikato Environment for Knowledge Analysis) tool. We present the results of comparing our hybrid algorithm created from aggregation with the distributive equation of selected classification algorithms (multilayer perceptron network, support vector machine, k-nearest neighbors, naïve Bayes, and random forests) with themselves on raw data.
摘要 本研究旨在根据临床数据和 24 小时 Holter 心电图监测结果,应用混合分类器预测是否存在严重冠状动脉疾病,并评估其实用性。我们的方法依赖于应用分布方程的集合分类器,并相应地聚集基础分类器。这种方法可能有助于医生管理冠状动脉疾病患者,特别是在有创诊断测试(即冠状动脉造影术)受限或存在禁忌症的情况下。本文包括对波兰克拉科夫雅盖隆大学医学院内科学系医学数据的实验结果。数据集包含临床数据、Holter ECG(24 小时心电图监测)数据和冠状动脉造影数据。在使用 WEKA(Waikato Environment for Knowledge Analysis,怀卡托知识分析环境)工具对数据集进行分类器性能评估时,采用了一出交叉验证技术。我们介绍了在原始数据上将我们的混合算法与所选分类算法(多层感知器网络、支持向量机、k-近邻、奈夫贝叶斯和随机森林)的分配方程聚合而成的混合算法进行比较的结果。
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引用次数: 0
Constant Q–Transform–Based Deep Learning Architecture for Detection of Obstructive Sleep Apnea 用于检测阻塞性睡眠呼吸暂停的基于恒定 Q 变换的深度学习架构
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0036
Usha Rani Kandukuri, A. J. Prakash, Kiran Kumar Patro, B. Neelapu, R. Tadeusiewicz, Paweł Pławiak
Abstract Obstructive sleep apnea (OSA) is a long-term sleep disorder that causes temporary disruption in breathing while sleeping. Polysomnography (PSG) is the technique for monitoring different signals during the patient’s sleep cycle, including electroencephalogram (EEG), electromyography (EMG), electrocardiogram (ECG), and oxygen saturation (SpO2). Due to the high cost and inconvenience of polysomnography, the usefulness of ECG signals in detecting OSA is explored in this work, which proposes a two-dimensional convolutional neural network (2D-CNN) model for detecting OSA using ECG signals. A publicly available apnea ECG database from PhysioNet is used for experimentation. Further, a constant Q-transform (CQT) is applied for segmentation, filtering, and conversion of ECG beats into images. The proposed CNN model demonstrates an average accuracy, sensitivity and specificity of 91.34%, 90.68% and 90.70%, respectively. The findings obtained using the proposed approach are comparable to those of many other existing methods for automatic detection of OSA.
摘要 阻塞性睡眠呼吸暂停(OSA)是一种长期睡眠障碍,会导致睡眠时呼吸暂时中断。多导睡眠图(PSG)是一种监测患者睡眠周期中不同信号的技术,包括脑电图(EEG)、肌电图(EMG)、心电图(ECG)和血氧饱和度(SpO2)。由于多导睡眠图的高成本和不便性,本研究探讨了心电图信号在检测 OSA 中的实用性,并提出了一种利用心电图信号检测 OSA 的二维卷积神经网络(2D-CNN)模型。实验使用了 PhysioNet 上公开的呼吸暂停心电图数据库。此外,还采用恒定 Q 变换 (CQT) 进行分割、过滤,并将心电图搏动转换为图像。所提出的 CNN 模型的平均准确率、灵敏度和特异性分别为 91.34%、90.68% 和 90.70%。使用所提议的方法得出的结果可与其他许多现有的 OSA 自动检测方法相媲美。
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引用次数: 0
Computing a Mechanism for a Bayesian and Partially Observable Markov Approach 计算贝叶斯和部分可观测马尔可夫方法的机制
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0034
J. Clempner, A. Poznyak
Abstract The design of incentive-compatible mechanisms for a certain class of finite Bayesian partially observable Markov games is proposed using a dynamic framework. We set forth a formal method that maintains the incomplete knowledge of both the Bayesian model and the Markov system’s states. We suggest a methodology that uses Tikhonov’s regularization technique to compute a Bayesian Nash equilibrium and the accompanying game mechanism. Our framework centers on a penalty function approach, which guarantees strong convexity of the regularized reward function and the existence of a singular solution involving equality and inequality constraints in the game. We demonstrate that the approach leads to a resolution with the smallest weighted norm. The resulting individually rational and ex post periodic incentive compatible system satisfies this requirement. We arrive at the analytical equations needed to compute the game’s mechanism and equilibrium. Finally, using a supply chain network for a profit maximization problem, we demonstrate the viability of the proposed mechanism design.
摘 要 本文利用动态框架提出了如何为某类有限贝叶斯部分可观测马尔可夫博弈设计激励相容机制。我们提出了一种保持贝叶斯模型和马尔可夫系统状态的不完全知识的正式方法。我们提出了一种使用提霍诺夫正则化技术计算贝叶斯纳什均衡和相应博弈机制的方法。我们的框架以惩罚函数方法为核心,该方法保证了正则化奖励函数的强凸性,以及博弈中涉及平等和不平等约束的奇异解的存在。我们证明,这种方法可以得到加权规范最小的解。由此产生的个体理性和事后周期性激励兼容系统满足这一要求。我们得出了计算博弈机制和均衡所需的分析方程。最后,我们利用供应链网络来解决利润最大化问题,证明了所提出的机制设计是可行的。
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引用次数: 0
Applications of the Fractional Sturm–Liouville Difference Problem to the Fractional Diffusion Difference Equation 分数斯特姆-利乌维尔差分问题在分数扩散差分方程中的应用
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0025
A. Malinowska, T. Odzijewicz, A. Poskrobko
Abstract This paper deals with homogeneous and non-homogeneous fractional diffusion difference equations. The fractional operators in space and time are defined in the sense of Grünwald and Letnikov. Applying results on the existence of eigenvalues and corresponding eigenfunctions of the Sturm–Liouville problem, we show that solutions of fractional diffusion difference equations exist and are given by a finite series.
摘要 本文涉及同质和非同质分数扩散差分方程。空间和时间上的分数算子是在格伦瓦尔德和列特尼科夫的意义上定义的。应用 Sturm-Liouville 问题的特征值和相应特征函数的存在性结果,我们证明分数扩散差分方程的解是存在的,并且是由有限级数给出的。
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引用次数: 0
Spike Patterns and Chaos in a Map–Based Neuron Model 基于图谱的神经元模型中的尖峰模式与混沌
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0028
Piotr Bartłomiejczyk, Frank Llovera Trujillo, Justyna Signerska-Rynkowska
Abstract The work studies the well-known map-based model of neuronal dynamics introduced in 2007 by Courbage, Nekorkin and Vdovin, important due to various medical applications. We also review and extend some of the existing results concerning β-transformations and (expanding) Lorenz mappings. Then we apply them for deducing important properties of spike-trains generated by the CNV model and explain their implications for neuron behaviour. In particular, using recent theorems of rotation theory for Lorenz-like maps, we provide a classification of periodic spiking patterns in this model.
摘要 本论文研究了库尔巴奇、内科金和弗多文于 2007 年提出的著名神经元动力学基于映射的模型,该模型因其在医学上的各种应用而具有重要意义。我们还回顾并扩展了有关 β 变换和(扩展)洛伦兹映射的一些现有成果。然后,我们将它们用于推导 CNV 模型生成的尖峰脉冲串的重要属性,并解释它们对神经元行为的影响。特别是,利用洛伦兹样图的最新旋转理论定理,我们对该模型中的周期性尖峰模式进行了分类。
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引用次数: 0
On the Analysis of a Mathematical Model of CAR–T Cell Therapy for Glioblastoma: Insights from a Mathematical Model 关于胶质母细胞瘤 CAR-T 细胞疗法数学模型的分析:数学模型的启示
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0027
M. Bodnar, U. Foryś, M. Piotrowska, Mariusz Bodzioch, J. A. Romero-Rosales, J. Belmonte-Beitia
Abstract Chimeric antigen receptor T (CAR-T) cell therapy has been proven to be successful against different leukaemias and lymphomas. Its success has led, in recent years, to its use being tested for different solid tumours, including glioblastoma, a type of primary brain tumour, characterised by aggressiveness and recurrence. This paper presents an analytical study of a mathematical model describing the competition of CAR-T and glioblastoma tumour cells, taking into account their immunosuppressive capacity. The model is formulated in a general way, and its basic properties are investigated. However, most of the analysis considers the model with exponential tumour growth, assuming this growth type for simplicity. The existence and stability of steady states are studied, and the subsequent focus is on two different types of treatment: constant and periodic. Finally, protocols for CAR-T cell therapy of glioblastoma are numerically derived; these are aimed at preventing the tumour from reaching a critical size and at prolonging the patients’ survival time as much as possible. The analytical and numerical results provide theoretical support for the treatment of glioblastoma using CAR-T cells.
摘要 嵌合抗原受体 T(CAR-T)细胞疗法已被证明能成功治疗各种白血病和淋巴瘤。近年来,它的成功促使人们开始对不同的实体瘤进行试验,其中包括胶质母细胞瘤,这是一种以侵袭性和复发性为特征的原发性脑肿瘤。本文介绍了一个数学模型的分析研究,该模型描述了 CAR-T 与胶质母细胞瘤肿瘤细胞之间的竞争,同时考虑到了它们的免疫抑制能力。该模型以一般的方式制定,并对其基本特性进行了研究。不过,大部分分析考虑的是肿瘤指数增长模型,为简单起见,假设了这种增长类型。研究了稳态的存在和稳定性,随后重点讨论了两种不同类型的治疗:恒定治疗和周期治疗。最后,数值推导了胶质母细胞瘤的 CAR-T 细胞治疗方案;这些方案旨在防止肿瘤达到临界大小,并尽可能延长患者的生存时间。分析和数值结果为使用 CAR-T 细胞治疗胶质母细胞瘤提供了理论支持。
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引用次数: 0
Investigation of the Lombard Effect Based on a Machine Learning Approach 基于机器学习方法的伦巴第效应研究
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0035
G. Korvel, P. Treigys, Krzysztof Kakol, Bożena Kostek
Abstract The Lombard effect is an involuntary increase in the speaker’s pitch, intensity, and duration in the presence of noise. It makes it possible to communicate in noisy environments more effectively. This study aims to investigate an efficient method for detecting the Lombard effect in uttered speech. The influence of interfering noise, room type, and the gender of the person on the detection process is examined. First, acoustic parameters related to speech changes produced by the Lombard effect are extracted. Mid-term statistics are built upon the parameters and used for the self-similarity matrix construction. They constitute input data for a convolutional neural network (CNN). The self-similarity-based approach is then compared with two other methods, i.e., spectrograms used as input to the CNN and speech acoustic parameters combined with the k-nearest neighbors algorithm. The experimental investigations show the superiority of the self-similarity approach applied to Lombard effect detection over the other two methods utilized. Moreover, small standard deviation values for the self-similarity approach prove the resulting high accuracies.
摘要 伦巴第效应是指在有噪音的情况下,说话者的音调、强度和持续时间会不由自主地增加。它使在嘈杂环境中更有效地交流成为可能。本研究旨在探讨一种检测语音朗伯德效应的有效方法。研究了干扰噪音、房间类型和人的性别对检测过程的影响。首先,提取与伦巴第效应产生的语音变化有关的声学参数。中期统计建立在这些参数之上,并用于自相似矩阵的构建。它们构成了卷积神经网络 (CNN) 的输入数据。然后,将基于自相似性的方法与其他两种方法进行比较,即作为 CNN 输入的频谱图和结合 k 近邻算法的语音声学参数。实验研究表明,应用于伦巴第效应检测的自相似性方法优于其他两种方法。此外,自相似性方法的标准偏差值较小,证明了该方法的高准确度。
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引用次数: 0
A Method of Lower and Upper Solutions for Control Problems and Application to a Model of Bone Marrow Transplantation 控制问题的上下解法及在骨髓移植模型中的应用
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0029
L. Parajdi, Radu Precup, Ioan Ştefan Haplea
Abstract A lower and upper solution method is introduced for control problems related to abstract operator equations. The method is illustrated on a control problem for the Lotka–Volterra model with seasonal harvesting and applied to a control problem of cell evolution after bone marrow transplantation.
摘要 针对与抽象算子方程有关的控制问题,介绍了一种上下求解方法。该方法在具有季节性收获的 Lotka-Volterra 模型的控制问题上进行了说明,并应用于骨髓移植后细胞演变的控制问题。
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引用次数: 0
Nonsmooth Optimization Control Based on a Sandwich Model with Hysteresis for Piezo–Positioning Systems 基于带滞后的三明治模型的压电定位系统非平滑优化控制
Pub Date : 2023-09-01 DOI: 10.34768/amcs-2023-0033
Sen Yang, Yonghong Tan, Ruili Dong, Qingyuan Tan
Abstract A nonsmooth optimization control (NOC) based on a sandwich model with hysteresis is proposed to control a micropositioning system (MPS) with a piezoelectric actuator (PEA). In this control scheme, the hysteresis phenomenon inherent in the PEA is described by a Duhem submodel embedded between two linear dynamic submodels that describe the behavior of the drive amplifier and the flexible hinge with load, respectively, thus constituting a sandwich model with hysteresis. Based on this model, a nonsmooth predictor for sandwich systems with hysteresis is constructed. To avoid the complicated online search for the optimal value of the generalized gradient at a nonsmooth point, the method of the so-called weighted estimation of generalized gradient is proposed. In order to compensate for the model error caused by model uncertainty, a model error compensator (MEC) is integrated into the online optimization control strategy. Afterwards, the stability of the control system is analyzed based on Lyapunov’s theory. Finally, the proposed NOC-MEC method is verified on an MPS with a PEA, and the corresponding experimental results are presented.
摘要 本文提出了一种基于带有滞后的三明治模型的非平滑优化控制(NOC),用于控制带有压电致动器(PEA)的微定位系统(MPS)。在该控制方案中,压电致动器固有的滞后现象由嵌入两个线性动态子模型之间的 Duhem 子模型来描述,这两个子模型分别描述驱动放大器和柔性铰链在负载作用下的行为,从而构成一个带滞后的三明治模型。在此模型的基础上,构建了带滞后的三明治系统的非光滑预测器。为了避免在非光滑点在线搜索广义梯度最优值的复杂过程,提出了所谓的广义梯度加权估计方法。为了补偿模型不确定性造成的模型误差,在线优化控制策略中集成了模型误差补偿器(MEC)。随后,基于 Lyapunov 理论分析了控制系统的稳定性。最后,在带有 PEA 的 MPS 上验证了所提出的 NOC-MEC 方法,并给出了相应的实验结果。
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引用次数: 0
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International Journal of Applied Mathematics and Computer Science
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