Pub Date : 2024-03-15DOI: 10.31612/2616-4868.1.2024.01
Svitlana O. Lytvak, Maksym V. Yeleynik, Liliia V. Chobitko, Olena Lytvak, Hennadiy P. Pasichnyk, Wojciech Dąbrowski
Introduction. Hemorrhagic stroke due to the rupture of the intracranial aneurysm (IA) is a typical clinical manifestation of the disease and one of the main causes of disability, affecting the quality of life in operated patients. The aim. To determine the feasibility and safety of implementing protocols for diabetes mellitus (DM) treatment as part of rehabilitation interventions in patients who have undergone surgery for the rupture of intracranial aneurysm (IA) in the brain. Materials and methods. To determine the effectiveness and safety of implementing diabetes mellitus (DM) treatment protocols in individually developed rehabilitation interventions following surgery for the rupture of intracranial aneurysm (IA) in the brain, a retrospective cohort study was conducted in parallel groups. Results. Sexual dysfunctions (SD) resulting from the rupture of IA are multifactorial. The causes of SD can be categorized as primary, secondary, and tertiary. Primary causes include damage to brain structures by hemorrhagic stroke or vascular ischemic events affecting sexual functioning, pre-existing medical conditions, and side effects related to medication therapy during treatment. Secondary causes encompass persistent sensorimotor disturbances due to a prior stroke. Issues related to cognitive, behavioral, and psychosocial adaptation constitute tertiary causes of SD. The effective and prompt correction of sexual dysfunction in patients following the rupture of cerebral blood vessel aneurysms largely depended on the proper administration of anesthesia during surgical interventions and intensive therapy in the perioperative period. This includes preoperative preparation and patient analgesia, the administration of anesthesia, and adequate postoperative care. Conclusions. The application of SD correction in men as part of rehabilitation measures from the 6th to the 24th month after surgical treatment of intracranial aneurysm (IA) has a positive impact, reducing SD regression from 88.9% (n=56/63) to 34.9% (n=22/63).
{"title":"THE ROLE AND CORRECTION OF SEXUAL DYSFUNCTION AS A COMPONENT OF THE QUALITY OF LIFE IN PATIENTS OPERATED ON FOR CEREBRAL ANEURYSM RUPTURE","authors":"Svitlana O. Lytvak, Maksym V. Yeleynik, Liliia V. Chobitko, Olena Lytvak, Hennadiy P. Pasichnyk, Wojciech Dąbrowski","doi":"10.31612/2616-4868.1.2024.01","DOIUrl":"https://doi.org/10.31612/2616-4868.1.2024.01","url":null,"abstract":"Introduction. Hemorrhagic stroke due to the rupture of the intracranial aneurysm (IA) is a typical clinical manifestation of the disease and one of the main causes of disability, affecting the quality of life in operated patients. \u0000The aim. To determine the feasibility and safety of implementing protocols for diabetes mellitus (DM) treatment as part of rehabilitation interventions in patients who have undergone surgery for the rupture of intracranial aneurysm (IA) in the brain. \u0000Materials and methods. To determine the effectiveness and safety of implementing diabetes mellitus (DM) treatment protocols in individually developed rehabilitation interventions following surgery for the rupture of intracranial aneurysm (IA) in the brain, a retrospective cohort study was conducted in parallel groups. \u0000Results. Sexual dysfunctions (SD) resulting from the rupture of IA are multifactorial. The causes of SD can be categorized as primary, secondary, and tertiary. Primary causes include damage to brain structures by hemorrhagic stroke or vascular ischemic events affecting sexual functioning, pre-existing medical conditions, and side effects related to medication therapy during treatment. Secondary causes encompass persistent sensorimotor disturbances due to a prior stroke. Issues related to cognitive, behavioral, and psychosocial adaptation constitute tertiary causes of SD. The effective and prompt correction of sexual dysfunction in patients following the rupture of cerebral blood vessel aneurysms largely depended on the proper administration of anesthesia during surgical interventions and intensive therapy in the perioperative period. This includes preoperative preparation and patient analgesia, the administration of anesthesia, and adequate postoperative care. \u0000Conclusions. The application of SD correction in men as part of rehabilitation measures from the 6th to the 24th month after surgical treatment of intracranial aneurysm (IA) has a positive impact, reducing SD regression from 88.9% (n=56/63) to 34.9% (n=22/63).","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"14 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140239086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-15DOI: 10.31612/2616-4868.1.2024.02
V. Shkorbotun, Maksym O. Ovsiienko, Y. Shkorbotun
The aim of the article: To study the influence of absolute and relative metric indicators of the lumen of certain parts of the internal nasal valve on the effectiveness of olfactory and respiratory functions of the nasal cavity. Materials and methods: A comparison of the metric values of the internal nasal valve, air resistance and odor perception in 32 patients after septoplasty was performed, depending on the quality of life and complaints according to SNOT 22. Group 1 consisted of 22 patients who complained of subjective feelings of nasal insufficiency (SNOT 22 – 9-20 scores). Control group consisted of 10 patients who were satisfied with septoplasty results (SNOT 22 – 0-7 scores). Rhinomanometry was performed according to the PARM method, olfactometry was carried out using the Sniffin’ Sticks psychophysical tests, and planimetry on CT was performed in the RadiAnt DICOM Viewer 2022.1 program, using the closed polygon tool. Results: Significant differences in the relative values of the ratio of the upper part of the valve area to the lower part were observed between the two groups of patients. A significant difference in better odor perception was noted in group 2. It was 0.7±0.02 in patients of the control group, and 0.4±0.02 in patients of Group 1. Air resistance in the nasal cavity during unilateral rhinomanometry did not significantly differ (0.28±0.04 and 0.26±0.07 Pa/cm3/sec). The average score during olfactometry in patients of the control group was 11.4±0.13, in patients of Group 1 it was 8.8±0.2, which indicates the presence of hyposmia (p>0.05). Conclusions: The ratio of the areas of the upper and lower parts of the internal nasal valve does not affect the overall airway resistance in the nose, but it can disrupt the distribution of air between the nasal passages. When evaluating the results of septoplasty, in particular, if the patient is not satisfied with nasal breathing, it is important to pay attention to the ventilation of the upper parts of the nasal cavity. One of the markers of its impairment may be hyposmia.
{"title":"RELATIVE METRIC INDICATORS OF THE UPPER AND LOWER PARTS OF THE INTERNAL NASAL VALVE LUMEN AND THEIR IMPACT ON NASAL RESPIRATORY AND OLFACTORY FUNCTIONS","authors":"V. Shkorbotun, Maksym O. Ovsiienko, Y. Shkorbotun","doi":"10.31612/2616-4868.1.2024.02","DOIUrl":"https://doi.org/10.31612/2616-4868.1.2024.02","url":null,"abstract":"The aim of the article: To study the influence of absolute and relative metric indicators of the lumen of certain parts of the internal nasal valve on the effectiveness of olfactory and respiratory functions of the nasal cavity. \u0000Materials and methods: A comparison of the metric values of the internal nasal valve, air resistance and odor perception in 32 patients after septoplasty was performed, depending on the quality of life and complaints according to SNOT 22. Group 1 consisted of 22 patients who complained of subjective feelings of nasal insufficiency (SNOT 22 – 9-20 scores). Control group consisted of 10 patients who were satisfied with septoplasty results (SNOT 22 – 0-7 scores). Rhinomanometry was performed according to the PARM method, olfactometry was carried out using the Sniffin’ Sticks psychophysical tests, and planimetry on CT was performed in the RadiAnt DICOM Viewer 2022.1 program, using the closed polygon tool. \u0000Results: Significant differences in the relative values of the ratio of the upper part of the valve area to the lower part were observed between the two groups of patients. A significant difference in better odor perception was noted in group 2. It was 0.7±0.02 in patients of the control group, and 0.4±0.02 in patients of Group 1. Air resistance in the nasal cavity during unilateral rhinomanometry did not significantly differ (0.28±0.04 and 0.26±0.07 Pa/cm3/sec). The average score during olfactometry in patients of the control group was 11.4±0.13, in patients of Group 1 it was 8.8±0.2, which indicates the presence of hyposmia (p>0.05). \u0000Conclusions: The ratio of the areas of the upper and lower parts of the internal nasal valve does not affect the overall airway resistance in the nose, but it can disrupt the distribution of air between the nasal passages. When evaluating the results of septoplasty, in particular, if the patient is not satisfied with nasal breathing, it is important to pay attention to the ventilation of the upper parts of the nasal cavity. One of the markers of its impairment may be hyposmia.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"58 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140239905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-15DOI: 10.31612/2616-4868.1.2024.05
V. Shkorbotun, Yaroslav S. Nachesa, Y. Shkorbotun
The aim of the study. To study the features of the location of cystic formations in the maxillary sinus based on CT scans and to determine their relationship with the pathology of the upper jaw teeth. Materials and methods. The study involved the analysis of 552 head computed tomography scans of patients referred for examination by an otolaryngologist or dentist. The total number of individuals examined was 552, comprising 44.7% females and 55.3% males, aged 18-74 years. The investigation was conducted using the NewTom GO device with a measurement range of 155-172 mGy/cm±10%, with an error of ±4.24%. Statistical processing of data was carried out using the STATISTICA v.12.6 software. Results. Out of 552 computed tomography images analyzed, 92 images of individual maxillary sinuses (MS) of 79 patients with single cysts were selected. They were divided into two groups. Group 1 involved patients with cysts on the lower wall of MS (n=76). Group 2 included patients with cysts on other walls (n=16). The assessment of the ratio of 4, 5, 6, 7 tooth roots of the upper jaw to the lower wall of the upper jaw showed that the protrusion frequency in Group 1 was significantly higher (42.1%) compared to Group 2 (18.7%). Meanwhile, the average thickness of the bone over these teeth in Group 2 was significantly greater (3.4 ± 1.09 mm) than in Group 1 (1.9 ± 0.92 mm) (p=0.0003). In both patient groups, the greatest thickness was observed over tooth 4, and the smallest over tooth 7. Additionally, in 33.7% of cases, the cyst was associated with involvement of deep structures of the projecting teeth and the spread of inflammation to the lower wall of MS. Conclusions. Among patients referred by an otolaryngologist or dentist for CT examination to radiologically verify pathological processes in the nasal cavity, paranasal sinuses, and the upper jaw teeth, MS cysts were detected in 19.6% of cases, with 83% of them being localized in its lower parts. In patients with cysts located in the lower parts of MS, the roots protruding into the sinus cavity and a thinner layer of bone over them are more frequently observed compared to those where cysts are located in other areas of MS. In patients with cystic formations in the alveolar recess of MS, radiological signs of pathology of the upper jaw teeth are detected in 34% of cases.
{"title":"RADIOLOGICAL FEATURES OF THE LOCATION OF CYSTIC FORMATIONS IN THE MAXILLARY SINUS AND THEIR RELATIONSHIP WITH ALVEOLAR BONE PATHOLOGY OF THE UPPER JAW","authors":"V. Shkorbotun, Yaroslav S. Nachesa, Y. Shkorbotun","doi":"10.31612/2616-4868.1.2024.05","DOIUrl":"https://doi.org/10.31612/2616-4868.1.2024.05","url":null,"abstract":"The aim of the study. To study the features of the location of cystic formations in the maxillary sinus based on CT scans and to determine their relationship with the pathology of the upper jaw teeth. \u0000Materials and methods. The study involved the analysis of 552 head computed tomography scans of patients referred for examination by an otolaryngologist or dentist. The total number of individuals examined was 552, comprising 44.7% females and 55.3% males, aged 18-74 years. The investigation was conducted using the NewTom GO device with a measurement range of 155-172 mGy/cm±10%, with an error of ±4.24%. Statistical processing of data was carried out using the STATISTICA v.12.6 software. \u0000Results. Out of 552 computed tomography images analyzed, 92 images of individual maxillary sinuses (MS) of 79 patients with single cysts were selected. They were divided into two groups. Group 1 involved patients with cysts on the lower wall of MS (n=76). Group 2 included patients with cysts on other walls (n=16). The assessment of the ratio of 4, 5, 6, 7 tooth roots of the upper jaw to the lower wall of the upper jaw showed that the protrusion frequency in Group 1 was significantly higher (42.1%) compared to Group 2 (18.7%). Meanwhile, the average thickness of the bone over these teeth in Group 2 was significantly greater (3.4 ± 1.09 mm) than in Group 1 (1.9 ± 0.92 mm) (p=0.0003). In both patient groups, the greatest thickness was observed over tooth 4, and the smallest over tooth 7. Additionally, in 33.7% of cases, the cyst was associated with involvement of deep structures of the projecting teeth and the spread of inflammation to the lower wall of MS. \u0000Conclusions. Among patients referred by an otolaryngologist or dentist for CT examination to radiologically verify pathological processes in the nasal cavity, paranasal sinuses, and the upper jaw teeth, MS cysts were detected in 19.6% of cases, with 83% of them being localized in its lower parts. In patients with cysts located in the lower parts of MS, the roots protruding into the sinus cavity and a thinner layer of bone over them are more frequently observed compared to those where cysts are located in other areas of MS. In patients with cystic formations in the alveolar recess of MS, radiological signs of pathology of the upper jaw teeth are detected in 34% of cases.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"26 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140240175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-15DOI: 10.31612/2616-4868.1.2024.04
S. Rustamian, I. P. Katerenchuk, Liudmyla K. Ovcharenko, Iryna V. Tsyganenko, Viktoriia V. Talash
Introduction. A progressive decrease in the rate of glomerular filtration is an independent risk factor for cardiovascular complications, as well as a marker of an unfavorable prognosis of cardiovascular diseases. Cardiovascular complications arising against the background of end-stage renal failure are the main cause of mortality in patients undergoing renal replacement therapy. The aim of the study was to determine the features and prevalence of cardiovascular complications in patients undergoing renal replacement therapy. Materials and methods. A retrospective study was conducted of 114 medical records of nephrology patients who were treated in the center of nephrology and dialysis of Poltava Regional Clinical Hospital n.a. M.V. Sklifosovsky. Patients were divided into three groups: two experimental and one control group. The first experimental group consisted of 44 (38.6%) patients who were on RRT by the method of programmed hemodialysis. The second experimental group consisted of 21 (18.4%) patients who were also undergoing RRT, but by the method of peritoneal dialysis. The control group consisted of 49 (43.0%) patients with CKD stages I-II. Analysis of laboratory data of traditional risk factors for cardiovascular complications (lipidogram), as well as non-traditional ones (level of calcium and phosphorus) was carried out. The frequency of cardiovascular complications in patients on renal replacement therapy was studied. Results. A statistically significant difference was found between the indicators of the atherogenicity index in the groups GD1 with CG1 (р=0.001) and GD2 with CG2 (р=0.031), PD1 and CG1 (р=0.005) and PD2 with CG2 (р=0.027). When analyzing the correlations between indicators of mineral metabolism in the experimental and control groups, it was found that weak and medium inverse correlations were observed in the experimental groups (GD1: -0.4703, GD2: -0.3219, PD1: -0,2146, PD2: -0.2784, respectively), while in the control groups a direct weak correlation was found (CG1 0.1975, CG2 0.2031, respectively). Chronic heart failure was detected in 75.0% of patients in the GD1 group, in 66.6% – in GD2, and in 100.0% of PD1 and PD2 patients. Valve calcification was observed in 35.0%, 29.1%, 33.3%, and 20.0%, respectively. Conclusions. Studying the features of cardiovascular complications, control of risk factors, which in any case occur in patients on dialysis therapy, is one of the main directions of controlling the underlying disease, reducing the risk of dangerous cardiovascular complications, prolonging life expectancy and its quality.
{"title":"CARDIOVASCULAR COMPLICATIONS IN PATIENTS ON RENAL REPLACEMENT THERAPY","authors":"S. Rustamian, I. P. Katerenchuk, Liudmyla K. Ovcharenko, Iryna V. Tsyganenko, Viktoriia V. Talash","doi":"10.31612/2616-4868.1.2024.04","DOIUrl":"https://doi.org/10.31612/2616-4868.1.2024.04","url":null,"abstract":"Introduction. A progressive decrease in the rate of glomerular filtration is an independent risk factor for cardiovascular complications, as well as a marker of an unfavorable prognosis of cardiovascular diseases. Cardiovascular complications arising against the background of end-stage renal failure are the main cause of mortality in patients undergoing renal replacement therapy. \u0000The aim of the study was to determine the features and prevalence of cardiovascular complications in patients undergoing renal replacement therapy. \u0000Materials and methods. A retrospective study was conducted of 114 medical records of nephrology patients who were treated in the center of nephrology and dialysis of Poltava Regional Clinical Hospital n.a. M.V. Sklifosovsky. Patients were divided into three groups: two experimental and one control group. The first experimental group consisted of 44 (38.6%) patients who were on RRT by the method of programmed hemodialysis. The second experimental group consisted of 21 (18.4%) patients who were also undergoing RRT, but by the method of peritoneal dialysis. The control group consisted of 49 (43.0%) patients with CKD stages I-II. Analysis of laboratory data of traditional risk factors for cardiovascular complications (lipidogram), as well as non-traditional ones (level of calcium and phosphorus) was carried out. The frequency of cardiovascular complications in patients on renal replacement therapy was studied. \u0000Results. A statistically significant difference was found between the indicators of the atherogenicity index in the groups GD1 with CG1 (р=0.001) and GD2 with CG2 (р=0.031), PD1 and CG1 (р=0.005) and PD2 with CG2 (р=0.027). When analyzing the correlations between indicators of mineral metabolism in the experimental and control groups, it was found that weak and medium inverse correlations were observed in the experimental groups (GD1: -0.4703, GD2: -0.3219, PD1: -0,2146, PD2: -0.2784, respectively), while in the control groups a direct weak correlation was found (CG1 0.1975, CG2 0.2031, respectively). Chronic heart failure was detected in 75.0% of patients in the GD1 group, in 66.6% – in GD2, and in 100.0% of PD1 and PD2 patients. Valve calcification was observed in 35.0%, 29.1%, 33.3%, and 20.0%, respectively. \u0000Conclusions. Studying the features of cardiovascular complications, control of risk factors, which in any case occur in patients on dialysis therapy, is one of the main directions of controlling the underlying disease, reducing the risk of dangerous cardiovascular complications, prolonging life expectancy and its quality.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"10 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140239146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-15DOI: 10.31612/2616-4868.1.2024.10
L. Kriachkova, Mykhailo Y. Korobko
Introduction: Strengthening the dental public health (DPH) of the pediatric population requires prioritizing development with the identification of key stakeholders and their leading functions. The aim. To analyze the current state and identify prospects for intra-industry and inter-sectoral cooperation in the process of strengthening the dental public health of the child population to justify ways of optimization. Materials and methods. A cross-sectional study using expert assessments involving 15 highly competent experts (competence level above 0.85) was conducted through a specially designed program. Bibliosemantic and sociological methods were employed. Expert assessments and stakeholder mapping were performed, visualizing the «authority-interest» relationship of different interested groups on a two-dimensional model. The results were analyzed using standard statistical methods with the application of Jupyter Notebook (https://jupyter.org/install). Intra-class correlation coefficients were used to assess the agreement of expert opinions. A significance level of p<0.05 was considered critical in testing all statistical hypotheses. Results. The graphical analysis allowed for the identification of stakeholders and determination of their roles in the DPH system. Groups with high and low levels of power and interest were identified. The agreement among experts regarding the determination of power and interest was respectively ICC=0.76 (95% CI 0.56 – 0.91) and ICC=0.79 (95% CI 0.59 – 0.92). The necessity of targeted efforts with each group, considering their capabilities and limitations, was emphasized. Key stakeholders included families, communities, family physicians, public health institutions, pediatric dentists, and others. Primary functions aimed at strengthening children’s dental health were attributed to influencing determinants of dental health, intersectoral collaboration and support for relevant initiatives at the local level are essential. Conclusions. The importance of developing and implementing programs aimed at improving the dental health of the child population has been established. Emphasis is placed on the significance of collaboration among various stakeholders in supporting a strategic approach to managing DPH.
{"title":"INVOLVEMENT OF DIFFERENT STAKEHOLDER GROUPS IN ENSURING CHILDREN’S DENTAL PUBLIC HEALTH: ANALYSIS AND PERSPECTIVES","authors":"L. Kriachkova, Mykhailo Y. Korobko","doi":"10.31612/2616-4868.1.2024.10","DOIUrl":"https://doi.org/10.31612/2616-4868.1.2024.10","url":null,"abstract":"Introduction: Strengthening the dental public health (DPH) of the pediatric population requires prioritizing development with the identification of key stakeholders and their leading functions. \u0000The aim. To analyze the current state and identify prospects for intra-industry and inter-sectoral cooperation in the process of strengthening the dental public health of the child population to justify ways of optimization. \u0000Materials and methods. A cross-sectional study using expert assessments involving 15 highly competent experts (competence level above 0.85) was conducted through a specially designed program. Bibliosemantic and sociological methods were employed. Expert assessments and stakeholder mapping were performed, visualizing the «authority-interest» relationship of different interested groups on a two-dimensional model. The results were analyzed using standard statistical methods with the application of Jupyter Notebook (https://jupyter.org/install). Intra-class correlation coefficients were used to assess the agreement of expert opinions. A significance level of p<0.05 was considered critical in testing all statistical hypotheses. \u0000Results. The graphical analysis allowed for the identification of stakeholders and determination of their roles in the DPH system. Groups with high and low levels of power and interest were identified. The agreement among experts regarding the determination of power and interest was respectively ICC=0.76 (95% CI 0.56 – 0.91) and ICC=0.79 (95% CI 0.59 – 0.92). The necessity of targeted efforts with each group, considering their capabilities and limitations, was emphasized. Key stakeholders included families, communities, family physicians, public health institutions, pediatric dentists, and others. Primary functions aimed at strengthening children’s dental health were attributed to influencing determinants of dental health, intersectoral collaboration and support for relevant initiatives at the local level are essential. \u0000Conclusions. The importance of developing and implementing programs aimed at improving the dental health of the child population has been established. Emphasis is placed on the significance of collaboration among various stakeholders in supporting a strategic approach to managing DPH.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"5 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140241213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.31612/2616-4868.8.2023.09
Volodymyr O. Melnyk, Iryna V. Synchuk
Introduction: glaucoma is an essential international social and medical problem, as it leads to irreversible blindness in patients worldwide. Organization of treatment and prevention of complications using the most effective methods is the most important task of ophthalmologists at the present stage of the fight against glaucoma. The purpose of the study: to evaluate the management of assistance under the monitoring program «STOP! Glaucoma» to patients with suspected glaucoma, open-angle glaucoma, and more advanced stages of glaucoma. To compare the effectiveness of therapeutic and surgical methods of glaucoma treatment. Materials and methods: To detect and prevent the progression of glaucoma in patients, the LLC «VISIOBUD» Clinic developed and implemented the monitoring program «Stop! Glaucoma». The main task of program was to analyze the dynamics of glaucomatous changes in the optic nerve and, based on this, to determine whether glaucoma compensation is complete and whether the patient does not need a more radical treatment method to preserve visual functions. The following methods of empirical research were used: systematic approach - to determine the research elements between which there are relationships of objects and their properties; observation - to identify signs and external manifestations of facts; comparison – to determine similarities and differences and identify regularities; measurement; monitoring. Results: In the course of the study, the dynamics of changes in intraocular pressure in patients who follow the annual monitoring program «Stop! Glaucoma» in the clinic of LLC «VISIOBUD». 4 groups of patients (116 patients – 156 eyes) were under observation. Installed that in 75% of cases, patients need surgical treatment of glaucoma to preserve their visual functions. Surgical treatment of patients with open-angle glaucoma effectively preserves vision in 89% of cases. Conclusions: Timely detection, monitoring, and treatment of initial signs of open-angle glaucoma and symptoms of its progression affects the preservation and prolongation of visual functions in patients. In the long term, surgical treatment of glaucoma is more cost-effective, as the need to use expensive hypotensive drops is significantly reduced (by 2.5 times).
{"title":"CLINICAL ASSESSMENT OF MANAGEMENT WHEN CHOOSING A METHOD OF PROVIDING CARE TO PATIENTS WITH OPEN-ANGLE GLAUCOMA","authors":"Volodymyr O. Melnyk, Iryna V. Synchuk","doi":"10.31612/2616-4868.8.2023.09","DOIUrl":"https://doi.org/10.31612/2616-4868.8.2023.09","url":null,"abstract":"Introduction: glaucoma is an essential international social and medical problem, as it leads to irreversible blindness in patients worldwide. Organization of treatment and prevention of complications using the most effective methods is the most important task of ophthalmologists at the present stage of the fight against glaucoma. The purpose of the study: to evaluate the management of assistance under the monitoring program «STOP! Glaucoma» to patients with suspected glaucoma, open-angle glaucoma, and more advanced stages of glaucoma. To compare the effectiveness of therapeutic and surgical methods of glaucoma treatment. Materials and methods: To detect and prevent the progression of glaucoma in patients, the LLC «VISIOBUD» Clinic developed and implemented the monitoring program «Stop! Glaucoma». The main task of program was to analyze the dynamics of glaucomatous changes in the optic nerve and, based on this, to determine whether glaucoma compensation is complete and whether the patient does not need a more radical treatment method to preserve visual functions. The following methods of empirical research were used: systematic approach - to determine the research elements between which there are relationships of objects and their properties; observation - to identify signs and external manifestations of facts; comparison – to determine similarities and differences and identify regularities; measurement; monitoring. Results: In the course of the study, the dynamics of changes in intraocular pressure in patients who follow the annual monitoring program «Stop! Glaucoma» in the clinic of LLC «VISIOBUD». 4 groups of patients (116 patients – 156 eyes) were under observation. Installed that in 75% of cases, patients need surgical treatment of glaucoma to preserve their visual functions. Surgical treatment of patients with open-angle glaucoma effectively preserves vision in 89% of cases. Conclusions: Timely detection, monitoring, and treatment of initial signs of open-angle glaucoma and symptoms of its progression affects the preservation and prolongation of visual functions in patients. In the long term, surgical treatment of glaucoma is more cost-effective, as the need to use expensive hypotensive drops is significantly reduced (by 2.5 times).","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"79 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.31612/2616-4868.8.2023.08
A. Efimenko, Oksana V. Ishchenko, I. Koshova, B. Murashevych, D.A. Stepanskyi
Introduction: Microorganisms colonizing the surface of dental implants can form biofilms that protect their microcolonies from mechanical impact, antimicrobial compounds, and immune factors. Prophylactic use of antibiotics during dental implantation can exert selective pressure on the development of antimicrobial resistance. In this context, N-chlorotaurine (NCT) is a promising compound to combat resistant agents. The aim is to investigate the efficacy of NCT against pathogens associated with dental implant complications. Materials and methods. A buffered 1% NCT solution adjusted to pH 7.1 was used for the study. Multidrug-resistant cultures (MDR) were identified. Determination of NCT activity was carried out by the agar and suspension method. The results. After standard antibiotic susceptibility testing, cultures classified as MDR were selected. 12 cultures were included in the MDR group, including seven S. aureus, three K. pneumoniae and three A. baumannii. MDR cultures of S. aureus had MRSA profile. Production of carbapenemases was confirmed in all MDR K. pneumoniae isolates, 2 of them showed production of metallo-β-lactamases. MDR isolates A. baumannii were also producers of metallo-β-lactamases. All 12 investigated MDR cultures were sensitive to NCT, the diameter of the zones of growth retardation was at least 15 mm. No significant difference was found between the effectiveness of 1% NCT solution against microorganisms with different mechanisms of drug resistance (t-test, p>0.05). When conducting studies in a liquid environment, a 1% NCT solution showed similar results, all MDR cultures were sensitive and showed a decrease in the microbial load (CFU/ml) by at least 2 log10 steps already 15 minutes after the start of the study. Notably, there was no significant difference in the efficacy of NCT against conditionally susceptible and MDR agents. Conclusions. Reducing the threat and burden of MDR pathogens is one of the goals announced by WHO and the Centres for Disease Control. Our study clearly confirms that various antibiotic resistance mechanisms do not affect the bactericidal activity of NCT, making it promising for the treatment of resistant infections.
{"title":"THE PERSPECTIVE OF N-CHLOROTAURINE INFLUENCE ON MULTI-DRUF RESISTANT MICROORGANISMS ASSOCIATED WITH DENTAL IMPLANTATION FAILURE","authors":"A. Efimenko, Oksana V. Ishchenko, I. Koshova, B. Murashevych, D.A. Stepanskyi","doi":"10.31612/2616-4868.8.2023.08","DOIUrl":"https://doi.org/10.31612/2616-4868.8.2023.08","url":null,"abstract":"Introduction: Microorganisms colonizing the surface of dental implants can form biofilms that protect their microcolonies from mechanical impact, antimicrobial compounds, and immune factors. Prophylactic use of antibiotics during dental implantation can exert selective pressure on the development of antimicrobial resistance. In this context, N-chlorotaurine (NCT) is a promising compound to combat resistant agents. The aim is to investigate the efficacy of NCT against pathogens associated with dental implant complications. Materials and methods. A buffered 1% NCT solution adjusted to pH 7.1 was used for the study. Multidrug-resistant cultures (MDR) were identified. Determination of NCT activity was carried out by the agar and suspension method. The results. After standard antibiotic susceptibility testing, cultures classified as MDR were selected. 12 cultures were included in the MDR group, including seven S. aureus, three K. pneumoniae and three A. baumannii. MDR cultures of S. aureus had MRSA profile. Production of carbapenemases was confirmed in all MDR K. pneumoniae isolates, 2 of them showed production of metallo-β-lactamases. MDR isolates A. baumannii were also producers of metallo-β-lactamases. All 12 investigated MDR cultures were sensitive to NCT, the diameter of the zones of growth retardation was at least 15 mm. No significant difference was found between the effectiveness of 1% NCT solution against microorganisms with different mechanisms of drug resistance (t-test, p>0.05). When conducting studies in a liquid environment, a 1% NCT solution showed similar results, all MDR cultures were sensitive and showed a decrease in the microbial load (CFU/ml) by at least 2 log10 steps already 15 minutes after the start of the study. Notably, there was no significant difference in the efficacy of NCT against conditionally susceptible and MDR agents. Conclusions. Reducing the threat and burden of MDR pathogens is one of the goals announced by WHO and the Centres for Disease Control. Our study clearly confirms that various antibiotic resistance mechanisms do not affect the bactericidal activity of NCT, making it promising for the treatment of resistant infections.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"47 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.31612/2616-4868.8.2023.12
Hanna Fedorova, Nataliya Velychko, Olena Bogatyrova
Introduction. Thyronamines belong to agonists of TAAR1 - trace amine receptors in the brain. The mechanism of activation of the processes of autophagy and neuroplasticity under the action of a synthetic analogue of thyronamines – 4-(4-(2-aminoethoxy)benzyl)aniline is described. Since cerebrovascular disorders remain the most common among neurological diseases, the development and implementation of drugs with neuroprotective properties is considered a promising strategy for the treatment and rehabilitation of patients with ischemic stroke. The aim of the study was to elucidate the effect of 4-(4-(2-aminoethoxy)benzyl)aniline on the activity of GPO, SOD and the dynamics of changes in the level of TBARS in the brain of rats after modeling focal ischemia by transient occlusion of the left middle cerebral artery. Materials and methods. The 4-(4-(2-aminoethoxy)benzyl)aniline was synthesized. Changes in the activity of antioxidant enzymes and the accumulation of secondary LPO products that react with thiobarbituric acid (TBARS) in rat brain homogenates were observed after injection of the studied compound in different dosages, as well as 24 hours after modeling focal ischemia. A neurological deficit in experimental rats was detected by the Garcia scale and the vibrissae-evoked forelimb placing test. Results. Compilation of data made it possible to find a strong relationship between the amount of the injected analogue and the growth of GPO activity in the neurons of healthy animals. In 80% of rats, occlusion of the middle cerebral artery induced evident sensorimotor disorders. 24 hours after the administration of a synthetic analogue of thyronamine in the homogenates of the affected left hemisphere, the activity of glutathione peroxidase significantly increased, and the content of TBARS decreased, and a tendency to activation of SOD was also observed. Conclusions. The obtained data indicate a positive effect of 4-(4-(2-aminoethoxy) benzyl) aniline on antioxidant enzymes in the intact rat brain and after modeling of focal ischemia, which is the basis to continue research for the purpose of finding long-term neuroprotective effects.
{"title":"IMPACT OF THYRONAMINE ANALOGUE ON LIPID PEROXIDATION IN THE BRAIN OF RATS","authors":"Hanna Fedorova, Nataliya Velychko, Olena Bogatyrova","doi":"10.31612/2616-4868.8.2023.12","DOIUrl":"https://doi.org/10.31612/2616-4868.8.2023.12","url":null,"abstract":"Introduction. Thyronamines belong to agonists of TAAR1 - trace amine receptors in the brain. The mechanism of activation of the processes of autophagy and neuroplasticity under the action of a synthetic analogue of thyronamines – 4-(4-(2-aminoethoxy)benzyl)aniline is described. Since cerebrovascular disorders remain the most common among neurological diseases, the development and implementation of drugs with neuroprotective properties is considered a promising strategy for the treatment and rehabilitation of patients with ischemic stroke. The aim of the study was to elucidate the effect of 4-(4-(2-aminoethoxy)benzyl)aniline on the activity of GPO, SOD and the dynamics of changes in the level of TBARS in the brain of rats after modeling focal ischemia by transient occlusion of the left middle cerebral artery. Materials and methods. The 4-(4-(2-aminoethoxy)benzyl)aniline was synthesized. Changes in the activity of antioxidant enzymes and the accumulation of secondary LPO products that react with thiobarbituric acid (TBARS) in rat brain homogenates were observed after injection of the studied compound in different dosages, as well as 24 hours after modeling focal ischemia. A neurological deficit in experimental rats was detected by the Garcia scale and the vibrissae-evoked forelimb placing test. Results. Compilation of data made it possible to find a strong relationship between the amount of the injected analogue and the growth of GPO activity in the neurons of healthy animals. In 80% of rats, occlusion of the middle cerebral artery induced evident sensorimotor disorders. 24 hours after the administration of a synthetic analogue of thyronamine in the homogenates of the affected left hemisphere, the activity of glutathione peroxidase significantly increased, and the content of TBARS decreased, and a tendency to activation of SOD was also observed. Conclusions. The obtained data indicate a positive effect of 4-(4-(2-aminoethoxy) benzyl) aniline on antioxidant enzymes in the intact rat brain and after modeling of focal ischemia, which is the basis to continue research for the purpose of finding long-term neuroprotective effects.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":" 874","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.31612/2616-4868.8.2023.15
I. Gorpynchenko, Kamil R. Nurimanov, Olena Nedogonova
Introduction. The need to understand the pathophysiology of prostatitis is determined by its prevalence, usually chronic progressive course, significant impact on quality of life, fertility and sexuality. The modern arsenal of medicines allows us to achieve a clinically significant effect. Along with this, non-pharmacological methods are widely used to increase the effectiveness of treatment. However, despite significant successes in the treatment of prostatitis, the problems of insufficient efficiency remain unsolved by modern urology, and it is extremely difficult to help these patients. Understanding the pathophysiology of the disease has always been the key to successful diagnosis and treatment. That is why it is important to determine the mechanisms of development of painful manifestations of prostatitis. The aim. To describe the main molecular mechanisms of tissue damage reception, in particular of the prostate gland, which are perceived as pain sensations. Materials and methods. An evaluation of modern literature devoted to the mechanisms of creation of nerve impulses due to damage and inflammation of the prostate gland was carried out. The search was conducted in the MEDLINE and databases of the National Library of Ukraine named after V.I. Vernadsky. Results. The main molecular mechanisms of nociception in chronic prostatitis have been determined. A review of modern literature devoted to the study of pain mechanisms as a biologically significant signal of damage at the molecular level of reception is presented. Attention is focused on the features of nociception in prostatitis, its connection with the production of inflammatory mediators, possible mechanisms of hyperalgesia and allodynia. As a result of stress and tissue damage, the production and release of inflammatory mediators such as interleukins, interferon, prostaglandins, bradykinin, adenosine triphosphate, protons and nerve growth factor increase. These mediators activate pain receptors located on nerve endings and are ion channels of various types: transient receptor potential, acid, purinergic, and potassium ion leak channels. Conclusions. The presented literature data describe the mechanisms of nociception, hyperalgesia and allodynia in chronic prostatitis, the understanding of which can be the basis for the development of new methods of diagnosis and treatment.
{"title":"MOLECULAR MECHANISMS OF NOCICEPTION IN CHRONIC PROSTATITIS","authors":"I. Gorpynchenko, Kamil R. Nurimanov, Olena Nedogonova","doi":"10.31612/2616-4868.8.2023.15","DOIUrl":"https://doi.org/10.31612/2616-4868.8.2023.15","url":null,"abstract":"Introduction. The need to understand the pathophysiology of prostatitis is determined by its prevalence, usually chronic progressive course, significant impact on quality of life, fertility and sexuality. The modern arsenal of medicines allows us to achieve a clinically significant effect. Along with this, non-pharmacological methods are widely used to increase the effectiveness of treatment. However, despite significant successes in the treatment of prostatitis, the problems of insufficient efficiency remain unsolved by modern urology, and it is extremely difficult to help these patients. Understanding the pathophysiology of the disease has always been the key to successful diagnosis and treatment. That is why it is important to determine the mechanisms of development of painful manifestations of prostatitis. The aim. To describe the main molecular mechanisms of tissue damage reception, in particular of the prostate gland, which are perceived as pain sensations. Materials and methods. An evaluation of modern literature devoted to the mechanisms of creation of nerve impulses due to damage and inflammation of the prostate gland was carried out. The search was conducted in the MEDLINE and databases of the National Library of Ukraine named after V.I. Vernadsky. Results. The main molecular mechanisms of nociception in chronic prostatitis have been determined. A review of modern literature devoted to the study of pain mechanisms as a biologically significant signal of damage at the molecular level of reception is presented. Attention is focused on the features of nociception in prostatitis, its connection with the production of inflammatory mediators, possible mechanisms of hyperalgesia and allodynia. As a result of stress and tissue damage, the production and release of inflammatory mediators such as interleukins, interferon, prostaglandins, bradykinin, adenosine triphosphate, protons and nerve growth factor increase. These mediators activate pain receptors located on nerve endings and are ion channels of various types: transient receptor potential, acid, purinergic, and potassium ion leak channels. Conclusions. The presented literature data describe the mechanisms of nociception, hyperalgesia and allodynia in chronic prostatitis, the understanding of which can be the basis for the development of new methods of diagnosis and treatment.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.31612/2616-4868.8.2023.04
Vasyl I. Melenko, Iakіv V. Fishchenko, Lyudmila D. Kravchuk, Yevhenii E. Shcheholkov
The aіm of the study іs to evaluate the results of surgіcal treatment usіng the method of bіportal unіlateral іnterlamіnotomy wіth bіlateral decompressіon (ULBD) and to analyze complіcatіons іn patіents operated on for degeneratіve lumbar spіnal stenosіs. Materіals and methods. A total of 51 patіents were analyzed wіth the average age of 58±16.4 years, who had lumbar spіnal stenosіs and underwent bіlateral decompressіon usіng unіlateral іnterlamіnotomy (ULBD) at the Spіne Surgery Clіnіc of the State Іnstіtutіon "ІTO NAMS of Ukraіne". Results. Accordіng to the study results, іmmedіately after ULBD surgery, the level of paіn syndrome іn the back and lower lіmbs sіgnіfіcantly decreased. Іn the post-operatіve perіod, the paіn score іn the back by VAS decreased from 4.9 ± 2.3 cm to 3.2 ± 0.5 cm, and іn the lower lіmbs from 5.6 ± 2.1 cm to 1.2 ± 0.7 cm. However, the hіgh level of back paіn stіll remaіns due to the paіn іn the operated segment and the wound. After 3 months, the paіn score by VAS (back) was 1.1 ± 0.7 cm and 1.4 ± 0.4 cm іn the legs (p < 0.05). Posіtіve dynamіcs of VAS (back) contіnued after 6 months and 12 months wіth scores of 1.3 ± 0.5 cm and 0.9 ± 0.6 cm, respectіvely (p < 0.05). Paіn syndrome reductіon іn the lower lіmbs maіntaіned at the level of 0.9 ± 0.7 cm and 0.8 ± 0.6 cm after 6 months and 12 months, respectіvely (p < 0.05). The evaluatіon of results by MRІ іn the preoperatіve and post-operatіve perіod (the next day after the surgery) showed that the cross-sectіonal area іncreased from 1,01±0,05 cm2 to 2,01±0,02 cm2 on average. The average length of hospіtal stay for patіents was 2±1,2 days. Conclusіons. The ULBD technіque іs an effectіve method for decompressіon of the spіnal canal іn patіents wіth lumbar spіnal stenosіs. Unіlateral lamіnotomy wіth bіlateral decompressіon technіque (ULBD) allows reducіng muscle dіssectіon and decreasіng the degree of damage to the posterіor structures of the spіne.
{"title":"ENDOSCOPIC DECOMPRESSION IN LUMBAR SPINAL STENOSIS: RADIOLOGICAL AND CLINICAL RESULTS","authors":"Vasyl I. Melenko, Iakіv V. Fishchenko, Lyudmila D. Kravchuk, Yevhenii E. Shcheholkov","doi":"10.31612/2616-4868.8.2023.04","DOIUrl":"https://doi.org/10.31612/2616-4868.8.2023.04","url":null,"abstract":"The aіm of the study іs to evaluate the results of surgіcal treatment usіng the method of bіportal unіlateral іnterlamіnotomy wіth bіlateral decompressіon (ULBD) and to analyze complіcatіons іn patіents operated on for degeneratіve lumbar spіnal stenosіs. Materіals and methods. A total of 51 patіents were analyzed wіth the average age of 58±16.4 years, who had lumbar spіnal stenosіs and underwent bіlateral decompressіon usіng unіlateral іnterlamіnotomy (ULBD) at the Spіne Surgery Clіnіc of the State Іnstіtutіon \"ІTO NAMS of Ukraіne\". Results. Accordіng to the study results, іmmedіately after ULBD surgery, the level of paіn syndrome іn the back and lower lіmbs sіgnіfіcantly decreased. Іn the post-operatіve perіod, the paіn score іn the back by VAS decreased from 4.9 ± 2.3 cm to 3.2 ± 0.5 cm, and іn the lower lіmbs from 5.6 ± 2.1 cm to 1.2 ± 0.7 cm. However, the hіgh level of back paіn stіll remaіns due to the paіn іn the operated segment and the wound. After 3 months, the paіn score by VAS (back) was 1.1 ± 0.7 cm and 1.4 ± 0.4 cm іn the legs (p < 0.05). Posіtіve dynamіcs of VAS (back) contіnued after 6 months and 12 months wіth scores of 1.3 ± 0.5 cm and 0.9 ± 0.6 cm, respectіvely (p < 0.05). Paіn syndrome reductіon іn the lower lіmbs maіntaіned at the level of 0.9 ± 0.7 cm and 0.8 ± 0.6 cm after 6 months and 12 months, respectіvely (p < 0.05). The evaluatіon of results by MRІ іn the preoperatіve and post-operatіve perіod (the next day after the surgery) showed that the cross-sectіonal area іncreased from 1,01±0,05 cm2 to 2,01±0,02 cm2 on average. The average length of hospіtal stay for patіents was 2±1,2 days. Conclusіons. The ULBD technіque іs an effectіve method for decompressіon of the spіnal canal іn patіents wіth lumbar spіnal stenosіs. Unіlateral lamіnotomy wіth bіlateral decompressіon technіque (ULBD) allows reducіng muscle dіssectіon and decreasіng the degree of damage to the posterіor structures of the spіne.","PeriodicalId":502404,"journal":{"name":"Clinical and Preventive Medicine","volume":"42 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139131144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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