{"title":"Characteristics of relapsed and refractory paediatric Hodgkin lymphoma; a 10-year retrospective study of an LMIC","authors":"Quratulain Riaz, Rabel Gul, Vashma Junaid, Wasfa Farooq, Naema Khayyam","doi":"10.3332/ecancer.2024.1729","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1729","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"3 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141641512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-16DOI: 10.3332/ecancer.2024.1730
Mohammad Saad Salim Naviwala, Mirza Rameez Samar, Daania Shoaib, Fizza Akbar, Romana Idrees, Yasmin Abdul Rashid
{"title":"Esophageal squamous cell carcinoma in a patient with BRCA1 mutation: a rare association","authors":"Mohammad Saad Salim Naviwala, Mirza Rameez Samar, Daania Shoaib, Fizza Akbar, Romana Idrees, Yasmin Abdul Rashid","doi":"10.3332/ecancer.2024.1730","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1730","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141642123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.3332/ecancer.2024.1728
Luís Felipe Leiteda Silva, Erick Figueiredo Saldanha, Lucas Dinizda Conceição, Wolney de Andrade Martins, R. Altenburg Gismondi, Erito Marques de Souza Filho, Renata D’Alpino Peixoto
{"title":"Efficacy and safety of trifluridine/tipiracil plus bevacizumab across different subgroups of patients with refractory colorectal cancer: a meta-analysis","authors":"Luís Felipe Leiteda Silva, Erick Figueiredo Saldanha, Lucas Dinizda Conceição, Wolney de Andrade Martins, R. Altenburg Gismondi, Erito Marques de Souza Filho, Renata D’Alpino Peixoto","doi":"10.3332/ecancer.2024.1728","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1728","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"13 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.3332/ecancer.2024.1727
Fatima Shaukat, Tayyab Siddiqui, Yumna Ahmed, Muneeba Khan, Mariam Fahim, Asna Noor, Agha Muhammad Hammad Khan, Ahmed Nadeem Abbasi
Introduction: Multidisciplinary tumour boards (MDTs) play a vital role in providing high-quality cancer care. In Pakistan’s compromised healthcare system, there is a lack of tumour board establishment. To bridge this gap, we aimed to enhance medical education by exposing medical students to the processes and advantages of MDTs early in their careers through conducting a mock tumour board. This approach seeks to provide students with a practical understanding of cancer care and the collaborative decision-making involved in managing cancer patients. Methodology: A session took place at Jinnah Postgraduate Medical Centre in May, 2023, with participants voluntarily agreeing to attend. This session comprised six components: a Pretest questionnaire, a didactic lecture on the concept of tumour boards, an interactive group discussion following the lecture, a simulated tumour case presentation, a workshop simulating a tumour board scenario and a Posttest questionnaire. Results: A total of 80 participants were included in the study. The mean age of study participants was 22. Among these, 36 (45%) were in their final year, 34 (42.5%) in their fourth year and 10 (12.5%) in their third year. While the majority of students possessed a
{"title":"Assessing the effectiveness of tumour board education among medical students: a pre-post-test analysis","authors":"Fatima Shaukat, Tayyab Siddiqui, Yumna Ahmed, Muneeba Khan, Mariam Fahim, Asna Noor, Agha Muhammad Hammad Khan, Ahmed Nadeem Abbasi","doi":"10.3332/ecancer.2024.1727","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1727","url":null,"abstract":"Introduction: Multidisciplinary tumour boards (MDTs) play a vital role in providing high-quality cancer care. In Pakistan’s compromised healthcare system, there is a lack of tumour board establishment. To bridge this gap, we aimed to enhance medical education by exposing medical students to the processes and advantages of MDTs early in their careers through conducting a mock tumour board. This approach seeks to provide students with a practical understanding of cancer care and the collaborative decision-making involved in managing cancer patients. Methodology: A session took place at Jinnah Postgraduate Medical Centre in May, 2023, with participants voluntarily agreeing to attend. This session comprised six components: a Pretest questionnaire, a didactic lecture on the concept of tumour boards, an interactive group discussion following the lecture, a simulated tumour case presentation, a workshop simulating a tumour board scenario and a Posttest questionnaire. Results: A total of 80 participants were included in the study. The mean age of study participants was 22. Among these, 36 (45%) were in their final year, 34 (42.5%) in their fourth year and 10 (12.5%) in their third year. While the majority of students possessed a","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"23 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.3332/ecancer.2024.1726
J. Daniels, Leroy Baffoe-Krapim, Andrew Yaw Nyantakyi, Edwina Ayaaba Ayabilah, Judith Naa Odey Tackie, Kofi Adesi Kyei
{"title":"Perceptions of prostate cancer patients undergoing definitive radiotherapy on the impact of prostate cancer and radiation therapy on male sexuality","authors":"J. Daniels, Leroy Baffoe-Krapim, Andrew Yaw Nyantakyi, Edwina Ayaaba Ayabilah, Judith Naa Odey Tackie, Kofi Adesi Kyei","doi":"10.3332/ecancer.2024.1726","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1726","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.3332/ecancer.2024.1725
S. Estreller, J. Pilapil, F. I. Ting, I. Real, E. Dee
Purpose: Advance care planning (ACP) is generally part of patients’ rights and decision-making processes. It is a component of the patient–physician care dynamics, especially in the context of life-threatening illness. Little is known about ACP and the utilisation of advance directives in the Philippines, a country of 110 million people. The study aimed to explore the knowledge, attitudes and practices (KAPs) of resident physicians in a national university hospital in the Philippines regarding ACP for patients with advanced cancer. Methods: Using a cross-sectional design involving resident physicians, an online survey with a self-administered questionnaire was distributed and answered by a total of 202 respondents. Results: Results show that resident physicians generally: (1) view palliative and hospice medicine to be the same and without differences, (2) are comfortable with discussing ACP and prognosis of medical conditions with patients and their families, but (3) do not regularly initiate or offer ACP to them, (4) identify a lack of time, fear of imparting emotional distress to patients and their families and personal discomfort as barriers to conducting ACP and (5) have had no formal training for ACP but are willing to undergo such formation, given the opportunity. Conclusion: This study highlights the continuing need to bridge and unite KAPs pertaining to ACP among physicians. Further studies should be undertaken to device a proper training program and better explore the complexities of end-of-life care as it is experienced by Filipino patients with advanced cancer.
{"title":"Physicians’ knowledge, attitudes and practices on advance care planning for patients with advanced cancer in a National University Hospital in the Philippines","authors":"S. Estreller, J. Pilapil, F. I. Ting, I. Real, E. Dee","doi":"10.3332/ecancer.2024.1725","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1725","url":null,"abstract":"Purpose: Advance care planning (ACP) is generally part of patients’ rights and decision-making processes. It is a component of the patient–physician care dynamics, especially in the context of life-threatening illness. Little is known about ACP and the utilisation of advance directives in the Philippines, a country of 110 million people. The study aimed to explore the knowledge, attitudes and practices (KAPs) of resident physicians in a national university hospital in the Philippines regarding ACP for patients with advanced cancer. Methods: Using a cross-sectional design involving resident physicians, an online survey with a self-administered questionnaire was distributed and answered by a total of 202 respondents. Results: Results show that resident physicians generally: (1) view palliative and hospice medicine to be the same and without differences, (2) are comfortable with discussing ACP and prognosis of medical conditions with patients and their families, but (3) do not regularly initiate or offer ACP to them, (4) identify a lack of time, fear of imparting emotional distress to patients and their families and personal discomfort as barriers to conducting ACP and (5) have had no formal training for ACP but are willing to undergo such formation, given the opportunity. Conclusion: This study highlights the continuing need to bridge and unite KAPs pertaining to ACP among physicians. Further studies should be undertaken to device a proper training program and better explore the complexities of end-of-life care as it is experienced by Filipino patients with advanced cancer.","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"80 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.3332/ecancer.2024.1724
Rima Saad Rassam, H. Abu-Saad Huijer, Samar Noureddine, Ellen M Lavoie Smith, Joanne Wolfe, Souha Fares, Miguel R Abboud
Parents of children with cancer provide paediatric palliative care (PPC). However, the activities they perform remain underexplored, especially in low-and middle-income countries (LMICs) where the care heavily relies on family involvement. The aim of this study is to identify parental PPC tasks and intentions to perform PPC tasks and to determine their associated factors. A quantitative cross-sectional descriptive design was used to recruit parents of children with cancer from three major paediatric oncology centres in Lebanon. Data were collected through structured interviews using an adapted questionnaire. The statistical analyses included descriptive, bivariate and regression analyses of PPC tasks and intentions. One hundred and five participants completed the study. On average, parents performed 22 PPC activities. The findings suggested statistically significant associations of the number of PPC tasks with the participants’ marital status, number of people living with the child, the intentions to perform the tasks and the number of the child’s symptoms in the previous week. Examining parents’ tasks in PPC in LMICs, such as Lebanon, enhances knowledge of PPC practice in these regions and informs improvement strategies. These results promote PPC understanding, highlight factors influencing PPC delivery and provide a useful measure of PPC tasks performed by parents of children with cancer.
{"title":"Parents providing palliative care for children with cancer","authors":"Rima Saad Rassam, H. Abu-Saad Huijer, Samar Noureddine, Ellen M Lavoie Smith, Joanne Wolfe, Souha Fares, Miguel R Abboud","doi":"10.3332/ecancer.2024.1724","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1724","url":null,"abstract":"Parents of children with cancer provide paediatric palliative care (PPC). However, the activities they perform remain underexplored, especially in low-and middle-income countries (LMICs) where the care heavily relies on family involvement. The aim of this study is to identify parental PPC tasks and intentions to perform PPC tasks and to determine their associated factors. A quantitative cross-sectional descriptive design was used to recruit parents of children with cancer from three major paediatric oncology centres in Lebanon. Data were collected through structured interviews using an adapted questionnaire. The statistical analyses included descriptive, bivariate and regression analyses of PPC tasks and intentions. One hundred and five participants completed the study. On average, parents performed 22 PPC activities. The findings suggested statistically significant associations of the number of PPC tasks with the participants’ marital status, number of people living with the child, the intentions to perform the tasks and the number of the child’s symptoms in the previous week. Examining parents’ tasks in PPC in LMICs, such as Lebanon, enhances knowledge of PPC practice in these regions and informs improvement strategies. These results promote PPC understanding, highlight factors influencing PPC delivery and provide a useful measure of PPC tasks performed by parents of children with cancer.","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"160 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-04DOI: 10.3332/ecancer.2024.1710
B. Ayub, Fizza Asif Qureshi, Nabeel Humayun Hassan, Fatima Shaukat, T. Qureshi
Introduction: Squamous cell carcinoma (SCC) of the head and neck is a great burden globally, which is being tackled through treatment options of surgery, radiation therapy, chemotherapy, or a combination of these, to avoid disease-related mortality. Multidisciplinary tumour boards play a pivotal role in customising and deciding management plan based on clinical aspects. The objective of the study is to determine the concordance of opinion between the treatment plan of a primary physician and board members. Material and methods: This is a retrospective cross-sectional study that includes 137 head and neck carcinoma cases. They were discussed in the multidisciplinary tumour board meeting and were reviewed; all demographics were analysed including the tumour staging and the decisions of the primary physician was compared with those of the board. To check the concordance between primary surgeon plans or after board discussion Kappa agreement test was used. Results: Total of 137 patients were included in the study out of which 63 cases were pre-treatment and 74 cases were post-treatment, i.e., surgically treated cases, with the distribution being 46% and 54%, respectively. Most cases, totaling 120, were SCC, accounting for 80% of the total cases. Among the pre-treatment cases, T4a and N0 were the most common categories, with 29 and 40 cases, respectively. Similarly, in post-treatment cases, the majority fell into the T4a and N1 categories, with 29 and 38 cases, respectively. When comparing the primary surgeon's plan with the tumour board meeting decision, the agreement showed a value of 0.273, indicating a slight level of agreement between the two entities. Conclusion: Our data indicates that the multidisciplinary head and neck tumour board may have influenced the treatment plans of the primary surgeon, in approximately one in two patients (43.06%).
{"title":"Optimising head and neck cancer patient management: the crucial contributions of multidisciplinary tumour board decision-making","authors":"B. Ayub, Fizza Asif Qureshi, Nabeel Humayun Hassan, Fatima Shaukat, T. Qureshi","doi":"10.3332/ecancer.2024.1710","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1710","url":null,"abstract":"Introduction: Squamous cell carcinoma (SCC) of the head and neck is a great burden globally, which is being tackled through treatment options of surgery, radiation therapy, chemotherapy, or a combination of these, to avoid disease-related mortality. Multidisciplinary tumour boards play a pivotal role in customising and deciding management plan based on clinical aspects. The objective of the study is to determine the concordance of opinion between the treatment plan of a primary physician and board members. Material and methods: This is a retrospective cross-sectional study that includes 137 head and neck carcinoma cases. They were discussed in the multidisciplinary tumour board meeting and were reviewed; all demographics were analysed including the tumour staging and the decisions of the primary physician was compared with those of the board. To check the concordance between primary surgeon plans or after board discussion Kappa agreement test was used. Results: Total of 137 patients were included in the study out of which 63 cases were pre-treatment and 74 cases were post-treatment, i.e., surgically treated cases, with the distribution being 46% and 54%, respectively. Most cases, totaling 120, were SCC, accounting for 80% of the total cases. Among the pre-treatment cases, T4a and N0 were the most common categories, with 29 and 40 cases, respectively. Similarly, in post-treatment cases, the majority fell into the T4a and N1 categories, with 29 and 38 cases, respectively. When comparing the primary surgeon's plan with the tumour board meeting decision, the agreement showed a value of 0.273, indicating a slight level of agreement between the two entities. Conclusion: Our data indicates that the multidisciplinary head and neck tumour board may have influenced the treatment plans of the primary surgeon, in approximately one in two patients (43.06%).","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-25DOI: 10.3332/ecancer.2024.1699
Jad A. Najdi, Mariana El Hawa, Adnan El-Achkar, Nour Naji, Talar Telvizian, Maya Romani, Albert El Hajj, Deborah Mukherji
{"title":"Smoking cessation counselling patterns in cancer patients – survey of Lebanese physicians","authors":"Jad A. Najdi, Mariana El Hawa, Adnan El-Achkar, Nour Naji, Talar Telvizian, Maya Romani, Albert El Hajj, Deborah Mukherji","doi":"10.3332/ecancer.2024.1699","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1699","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"4 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140653939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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