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Gait Speed, Mobility, Balance, and Dual-Tasking Deficits Among People Living With HIV Globally: A Systematic Review and Meta-Analysis. 全球艾滋病病毒感染者的步速、活动能力、平衡能力和双重任务缺陷:系统回顾与元分析》。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-19 DOI: 10.1097/JNC.0000000000000503
Kaylie Amiro, Miranda Bowser, Madison Connell, Remi Desrosiers, Evangeline MacAlpine, Anita Shahzadi, Caitlin McArthur, Adria Quigley

Abstract: People living with HIV (PLWH) may experience premature physical deficits, including walking, mobility, and balance problems. The purpose was to measure deficits in walking, mobility, balance, and dual tasking in PLWH. The secondary objective was to make recommendations regarding the use of rehabilitation outcome measures. CINAHL, PubMed, and SPORTDiscus databases were searched. Two independent reviewers screened titles/abstracts and full-text articles, extracted data, and performed a quality assessment. Fifty-six articles with 14,053 PLWH and 8,454 uninfected controls were included. A meta-analysis revealed significantly worse performance among PLWH on the five times sit to stand mobility test versus controls (Cohen d = 0.68, 95% confidence interval [CI 0.08-1.29], p = .03). Meta-analyses revealed no differences between PLWH and controls for usual gait speed (Cohen d = -0.47, 95% CI [-1.10 to 0.15], p = .14) and fast gait speed (Cohen d = -0.39, 95% CI [-0.87 to 0.08], p = .10). Ten of 12 studies comparing PLWH with controls found differences in balance outcomes. PLWH have significantly worse mobility than uninfected controls.

摘要:艾滋病病毒感染者(PLWH)可能会过早出现身体缺陷,包括行走、移动和平衡问题。研究的目的是测量艾滋病病毒感染者在行走、移动、平衡和双重任务方面的缺陷。次要目的是就康复结果测量方法的使用提出建议。检索了 CINAHL、PubMed 和 SPORTDiscus 数据库。两位独立审稿人筛选了文章标题/摘要和全文,提取了数据并进行了质量评估。共收录了 56 篇文章,涉及 14,053 名 PLWH 和 8,454 名未受感染的对照者。一项荟萃分析显示,与对照组相比,PLWH 在五次坐立移动测试中的表现明显较差(Cohen d = 0.68,95% 置信区间 [CI 0.08-1.29],p = .03)。元分析表明,PLWH 与对照组在通常步速(Cohen d = -0.47,95% CI [-1.10 到 0.15],p = .14)和快速步速(Cohen d = -0.39,95% CI [-0.87 到 0.08],p = .10)方面没有差异。在对 PLWH 和对照组进行比较的 12 项研究中,有 10 项发现了平衡结果的差异。与未感染的对照组相比,PLWH 的活动能力明显较差。
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引用次数: 0
Thank You for the Opportunity. 感谢您提供这次机会。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 DOI: 10.1097/JNC.0000000000000507
Michael V Relf
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引用次数: 0
A Forecast of the HIV Clinician Workforce Need in the United States: Results of a Quantitative National Survey. 美国艾滋病临床医生队伍需求预测:全国定量调查结果。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 DOI: 10.1097/JNC.0000000000000495
Andrea Norberg, John Nelson, Haiqun Lin, Elizabeth Lazo, Dominic Stanislaus, Carolyn Chu, Philip Bolduc

Abstract: There is a decreasing HIV care workforce in the United States, whereas the need for HIV care and prevention continues to increase. To better understand this issue, a quantitative, anonymous, one-time, self-administered survey was conducted. The survey was completed by 1,004 prescribing clinicians currently providing HIV-related health care. Clinicians of younger age and Black race, advanced practice registered nurses, and family medicine physicians were more likely to report continuing with the same number of patients or increasing the number of patients in their HIV practice in the next 5 years. The need for more prescribing HIV care clinicians is paramount because 17.8% reported plans to stop HIV clinical care wholly or to decrease the number of people living with HIV in their practice over the next 5 years. The most common reasons for leaving include retirement, administrative burden, and burnout.

摘要:在美国,艾滋病护理人员队伍不断减少,而艾滋病护理和预防的需求却持续增加。为了更好地了解这一问题,我们开展了一项一次性匿名自填式定量调查。调查由 1004 名目前提供 HIV 相关医疗服务的临床医生完成。年龄较小、属于黑人种族的临床医生、高级执业注册护士和家庭医生更有可能表示,在未来 5 年内,他们将继续为相同数量的患者提供服务,或增加其艾滋病诊疗服务的患者数量。由于 17.8% 的人表示计划在未来 5 年内完全停止艾滋病临床治疗或减少其诊所中的艾滋病感染者人数,因此需要更多开具处方的艾滋病护理临床医生至关重要。最常见的离职原因包括退休、行政负担和职业倦怠。
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引用次数: 0
An Integrative Review of the Literature Examining Sexual Relationship Power, Depressive Symptoms, Silencing the Self, and HIV Vulnerability for Women in the United States. 对研究美国女性性关系能力、抑郁症状、自我沉默和艾滋病易感性的文献进行综合评述。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 DOI: 10.1097/JNC.0000000000000506
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引用次数: 0
Emotional Loneliness Is Related to Objective Cognitive Function in Older People With HIV in the Washington-Baltimore Area: A Cross-sectional Study. 情感孤独与华盛顿-巴尔的摩地区感染艾滋病病毒的老年人的客观认知功能有关:一项横断面研究。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-08-13 DOI: 10.1097/JNC.0000000000000491
Moka Yoo-Jeong, Raha M Dastgheyb, Eran F Shorer, Cornelia Demsky, Olivia Fox, Divya Inaganti, Sarah Kanner, Ava G Neijna, Alison Buchholz, Tracey E Wilson, Leah H Rubin

Abstract: Loneliness confers a significant risk to numerous health outcomes, including cognitive impairment. This study assessed the relationship between loneliness subtypes (social and emotional) and cognition in older people with HIV (OPWH ≥ 50 years). Forty-two participants (STET = 61.5 years; 48% male; 74% Black) completed the six-item De Jong Gierveld Loneliness Scale and measures assessing objective and subjective cognition and depressive symptoms (Patient Health Questionnaire [PHQ-9]). Loneliness-cognition associations were examined using linear regression. Models were first adjusted for age, sex, race, and education, and then PHQ-9 score. Mean emotional and social loneliness scores were 1.24 ( SD = 1.22) and 1.21 ( SD = 1.14), respectively. After sociodemographic and PHQ-9 adjustment, emotional, but not social, loneliness was associated with poorer objective cognitive performance on processing speed (Digit Symbol) and executive function (CalCAP™). Findings have potential clinical importance for interventions that target specific loneliness subtypes to optimize cognitive performance in OPWH.

摘要:孤独感会对包括认知障碍在内的多种健康结果带来重大风险。本研究评估了感染艾滋病毒的老年人(OPWH ≥ 50 岁)的孤独亚型(社交和情感)与认知之间的关系。42 名参与者(STET = 61.5 岁;48% 为男性;74% 为黑人)完成了由 6 个项目组成的 De Jong Gierveld 孤独感量表以及评估客观和主观认知和抑郁症状的测量方法(患者健康问卷 [PHQ-9])。孤独感与认知的关系采用线性回归法进行检验。首先对模型进行年龄、性别、种族和教育程度调整,然后对 PHQ-9 分数进行调整。情感孤独和社交孤独的平均得分分别为 1.24(SD = 1.22)和 1.21(SD = 1.14)。经过社会人口学和PHQ-9调整后,情感孤独(而非社会孤独)与处理速度(数字符号)和执行功能(CalCAP™)的客观认知表现较差有关。研究结果对于针对特定孤独亚型进行干预以优化 OPWH 的认知表现具有潜在的临床意义。
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引用次数: 0
An Integrative Review of the Literature Examining Sexual Relationship Power, Depressive Symptoms, Silencing the Self, and HIV Vulnerability for Women in the United States. 对研究美国女性性关系能力、抑郁症状、自我沉默和艾滋病易感性的文献进行综合评述。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 DOI: 10.1097/JNC.0000000000000498
Wanda L Goodwyn, Courtney Caiola, Donna Roberson

Abstract: The purpose of our integrative review was to synthesize the literature examining relationships between depressive symptoms, silencing the self (STS), sexual relationship power (SRP), and HIV vulnerability among women in the United States. Literature searches were conducted through CINAHL, MEDLINE, PsycINFO, SCOPUS, Sociological Abstracts, and SocINDEX. Integrative review methodology of Whittemore and Knafl guided the review process, and 37 articles met inclusion criteria. The Theory of Gender and Power, modified by Wingood and DiClemente, was the guiding framework to organize and synthesize findings. Primary findings suggest that depressive symptoms, STS, and SRP in relationships may individually influence women's vulnerability for acquiring HIV, yet research lags behind. Evidence documenting relationships between these factors is insufficient to draw generalizable conclusions. Findings suggest that the current literature on this topic does not reflect those women most highly affected by HIV and those who identify as African American or Black in the Southeast region of the United States.

摘要:我们的综合综述旨在对研究美国女性抑郁症状、自我沉默(STS)、性关系权力(SRP)和艾滋病易感性之间关系的文献进行综合。文献检索通过 CINAHL、MEDLINE、PsycINFO、SCOPUS、Sociological Abstracts 和 SocINDEX 进行。在 Whittemore 和 Knafl 的综合综述方法指导下,共有 37 篇文章符合纳入标准。由 Wingood 和 DiClemente 修改的 "性别与权力理论 "是组织和综合研究结果的指导框架。主要研究结果表明,抑郁症状、STS 和人际关系中的 SRP 可能会单独影响女性感染 HIV 的可能性,但相关研究却相对滞后。记录这些因素之间关系的证据不足以得出具有普遍意义的结论。研究结果表明,目前有关这一主题的文献没有反映出美国东南部地区受艾滋病毒影响最严重的妇女以及那些被认定为非裔美国人或黑人的妇女。
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引用次数: 0
Assessing the Disruption of Health Services During the COVID-19 Pandemic Among Adults Living With HIV by Age in Essex County, NJ: A Cross-Sectional Study. 评估 COVID-19 大流行期间新泽西州埃塞克斯县按年龄划分的成人 HIV 感染者医疗服务中断情况:一项横断面研究。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-26 DOI: 10.1097/JNC.0000000000000499
Kristen D Krause, Anita G Karr, Juhi Aggarwal, Sanjana Subramhanya, Michelle DallaPiazza, Shobha Swaminathan, Pamela Valera, Perry N Halkitis, Stephanie Shiau

Abstract: At the onset of the COVID-19 pandemic, clinicians and researchers were concerned about its impact on the health of people living with HIV (PLWH). Although mitigation measures during the early part of the pandemic used telehealth, it was uncertain whether PLWH would be amenable to this type of care and whether health outcomes would be affected. PLWH actively seeking treatment at a large urban outpatient practice in Essex County, New Jersey, were interviewed from October 2020 to June 2021 about their health-related experiences during COVID-19. The sample was dichotomized by age (< 55 and ≥ 55). In all, participants (69.2%, n = 92) used telehealth during this period, 85.0% ( n = 113) actively tested for COVID-19, with only 7% ( n = 8) testing positive at the time of interview. Our findings demonstrate that PLWH who engaged with health care before the COVID-19 pandemic continued doing that and had relatively favorable health outcomes with few differences by age.

摘要:在 COVID-19 大流行开始时,临床医生和研究人员都很担心它对艾滋病毒感染者(PLWH)健康的影响。尽管在大流行初期采取的缓解措施中使用了远程医疗技术,但仍无法确定艾滋病感染者是否适合这种医疗方式,也无法确定其健康状况是否会受到影响。2020 年 10 月至 2021 年 6 月期间,新泽西州埃塞克斯县一家大型城市门诊诊所对积极寻求治疗的 PLWH 进行了访谈,了解他们在 COVID-19 期间与健康相关的经历。样本按年龄进行二分(< 55 岁和≥ 55 岁)。总之,参与者(69.2%,n = 92)在此期间使用了远程保健,85.0%(n = 113)积极接受了 COVID-19 检测,仅有 7%(n = 8)在访谈时检测结果呈阳性。我们的研究结果表明,在 COVID-19 大流行之前接受过医疗保健服务的 PLWH 继续这样做,并获得了相对较好的健康结果,不同年龄段的差异很小。
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引用次数: 0
Perspectives and Factors Related to Pre-exposure Prophylaxis Use Among Young Men Who Have Sex With Men in the United States: A Mixed-Methods Study on the Role of History of PrEP Use. 美国年轻男男性行为者使用暴露前预防疗法的观点和相关因素:关于 PrEP 使用历史的作用的混合方法研究》(A Mixed-Methods Study on the Role of History of PrEP Use)。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-08-29 DOI: 10.1097/JNC.0000000000000489
Junye Ma, Zach Soberano, Bryce F Stamp, Matthew Rosso, Lisa Hightow-Weidman, Kimberly A Powers, Jacob Benjamin Stocks, Sybil Hosek, Keith J Horvath

Abstract: This study quantitatively examined factors related to young men who have sex with men (YMSM)'s decisions to use pre-exposure prophylaxis (PrEP) by their history of PrEP use and qualitatively elicited their perspectives on PrEP options. Higher proportions of YMSM who had never used (vs. ever used) PrEP considered the following factors as important in their decisions to use PrEP: (a) Returning to PrEP follow-up visits ( p = .02), (b) having to talk about sex/PrEP with providers ( p = .013), (c) people assuming they are infected with HIV ( p = .021), (d) family finding out about their PrEP use ( p = .001), and (e) friends finding out about their PrEP use ( p = .008). Through inductive content analysis, qualitative data showed that a higher proportion of YMSM who had never used PrEP (vs. ever used) expressed concerns about HIV stigma from nonaffirming health care providers and the potential risk of inadvertently revealing their LGBTQ+ identity to others, which were described as potential barriers to PrEP use. Overall, our findings suggest that future interventions may consider tailoring PrEP messaging to YMSM's history of PrEP use, which may ultimately increase PrEP uptake and adherence.

摘要:本研究根据年轻男男性行为者(YMSM)使用 PrEP 的历史,定量研究了与他们决定使用暴露前预防疗法(PrEP)相关的因素,并从定性角度了解了他们对 PrEP 选择的看法。在从未使用过(与曾经使用过)PrEP 的男男性行为者中,认为以下因素对其决定使用 PrEP 有重要影响的比例较高:(a) PrEP 复诊(p = 0.02),(b) 必须与提供者谈论性/PrEP(p = 0.013),(c) 人们认为他们感染了 HIV(p = 0.021),(d) 家人发现他们使用 PrEP(p = 0.001),以及 (e) 朋友发现他们使用 PrEP(p = 0.008)。通过归纳内容分析,定性数据显示,从未使用过 PrEP(相对于曾经使用过)的青年男性同性恋者中,有较高比例的人对来自不认可他们的医疗服务提供者的艾滋病污名化以及无意中向他人透露其 LGBTQ+ 身份的潜在风险表示担忧,并将其视为使用 PrEP 的潜在障碍。总之,我们的研究结果表明,未来的干预措施可以考虑根据 YMSM 使用 PrEP 的历史记录定制 PrEP 信息,这最终可能会提高 PrEP 的接受率和坚持率。
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引用次数: 0
Smoking and Type 1 Versus Type 2 Myocardial Infarction Among People With HIV in the United States: Results from the Center for AIDS Research Network Integrated Clinical Systems Cohort. 美国艾滋病病毒感染者中吸烟与 1 型和 2 型心肌梗死的关系。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-06 DOI: 10.1097/JNC.0000000000000492
Heidi M Crane, Robin M Nance, Stephanie A Ruderman, Lydia N Drumright, L Sarah Mixson, Susan R Heckbert, Matthew J Feinstein, Matthew J Budoff, Laura Bamford, Edward Cachay, Sonia Napravnik, Richard D Moore, Jeanne Keruly, Amanda L Willig, Greer A Burkholder, Andrew Hahn, Jimmy Ma, Rob Fredericksen, Michael S Saag, Geetanjali Chander, Mari M Kitahata, Kristina Crothers, Kenneth H Mayer, Conall O'Cleirigh, Karen Cropsey, Bridget M Whitney, Joseph A C Delaney

Abstract: Smoking is a myocardial infarction (MI) risk factor among people with HIV (PWH). Questions persist regarding the role of smoking behaviors and measurements (e.g., intensity, duration) on MI risk. We used Cox proportional hazards regression to compare the association of smoking parameterization with incidents of type 1 and type 2 MI and whether smoking intensity or duration improves MI risk prediction among PWH. Among 11,637 PWH, 37% reported currently smoking, and there were 346 MIs. Current smoking was associated with type 1 (84% increased risk) but not type 2 MI in adjusted analyses. The type 1 MI model with pack years had the best goodness of fit compared with other smoking parameterizations. Ever or never parameterization and smoking diagnosis data had significantly poorer model fit. These results highlight the importance of differentiating MI types and performing patient-based smoking assessments to improve HIV care and research rather than relying on smoking status from diagnoses.

摘要:吸烟是艾滋病病毒感染者(PWH)心肌梗死(MI)的危险因素之一。关于吸烟行为和测量方法(如强度、持续时间)对心肌梗死风险的作用,一直存在疑问。我们使用 Cox 比例危险回归法比较了吸烟参数与 1 型和 2 型心肌梗死发病率的关系,以及吸烟强度或持续时间是否能改善对艾滋病感染者心肌梗死风险的预测。在 11637 名威尔士人中,37% 的人表示目前正在吸烟,共发生了 346 例心肌梗死。在调整分析中,当前吸烟与 1 型心肌梗死(风险增加 84%)有关,但与 2 型心肌梗死无关。与其他吸烟参数化方法相比,1型心肌梗死模型的包年拟合度最高。曾经或从不参数化以及吸烟诊断数据的模型拟合度明显较差。这些结果凸显了区分MI类型和进行基于患者的吸烟评估对改善艾滋病护理和研究的重要性,而不是依赖于诊断中的吸烟状况。
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引用次数: 0
Validation and Refinement of the Self-Regulatory HIV/AIDS Symptom Management Model Among People With HIV in China Using Path Analysis: A Secondary Data Analysis. 艾滋病病毒感染者生活质量的路径分析:自我调节艾滋病症状管理模式的验证与完善。
IF 1.6 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-08-13 DOI: 10.1097/JNC.0000000000000493
Meilian Xie, Aiping Wang, Zhiyun Zhang, Kerong Wang, Yanping Yu

Abstract: This study explored the path affecting the quality of life (QOL) of people with HIV in China and clarified the applicability and interpretability of the Self-Regulatory HIV/AIDS Symptom Management Model. We conducted a cross-sectional survey in nine regions of China and collected information about demographics, symptom experience, social support, perceived symptom manageability, self-efficacy, and QOL. A total of 711 patients participated in this survey. After four rounds of path analysis were conducted, the most fit indices met the standards (χ 2 /df = 2.633, Root Mean Square Error of Approximation = 0.081, Goodness-of-Fit Index/Adjusted Goodness-of-Fit Index/Comparative Fit Index/Incremental Fit Index/Tucker-Lewis Coefficient > 0.9), and the relationships between variables were statistically significant ( p < .05). Among all the pathways, social support had the most significant impact on the QOL, with a total path coefficient of 0.665. Symptom experience, as a negative factor, had a total effect value of -0.361. This study showed how all the factors influencing QOL were interconnected, serving as a crucial theoretical foundation for intervention strategies in future clinical practice.

摘要:本研究探讨了影响中国艾滋病病毒感染者生活质量(QOL)的路径,并阐明了自律性艾滋病症状管理模型的适用性和可解释性。我们在中国九个地区进行了横断面调查,收集了有关人口统计学、症状体验、社会支持、感知症状可控性、自我效能和 QOL 的信息。共有 711 名患者参与了此次调查。经过四轮路径分析,大部分拟合指数符合标准(χ2/df = 2.633,近似均方根误差 = 0.081,拟合优度指数/调整后拟合优度指数/比较拟合指数/增量拟合指数/塔克-刘易斯系数 > 0.9),变量之间的关系具有统计学意义(P < .05)。在所有路径中,社会支持对 QOL 的影响最为显著,总路径系数为 0.665。症状体验作为一个负面因素,其总效应值为-0.361。这项研究显示了影响 QOL 的所有因素是如何相互关联的,为今后临床实践中的干预策略提供了重要的理论基础。
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引用次数: 0
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Janac-Journal of the Association of Nurses in Aids Care
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