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Lower incisor position in skeletal Class III malocclusion patients: a comparative study of orthodontic camouflage and orthognathic surgery 骨骼Ⅲ类错颌畸形患者的下切牙位置:正畸伪装与正颌外科手术的比较研究
Pub Date : 2024-05-06 DOI: 10.2319/122523-856.1
Hao Liu, Yuning Zhang, Wenhsuan Lu, Yuhui Yang, Xiaomo Liu, Si Chen, Weiran Li, Bing Han
To determine the difference between orthodontic camouflage and orthodontic-orthognathic surgery using the traditional cephalometric measurement IMPA and the newly proposed IA/PAMD, the angle between the long axis of the lower incisor (IA) and the principal axis of the mandibular alveolus (PAMD). This study included 40 cases each in the orthodontic camouflage group (OG) and orthodontic-orthognathic surgery group (SG). The differences between the IMPA and IA/PAMD before and after treatment were compared between the two groups. T0 lateral cephalometric images of the 10 cases with the highest and lowest increase in the IA/PAMD were analyzed to identify characteristics associated with a higher risk of overdecompensation of the lower incisors during presurgical orthodontic treatment. Both the OG and SG showed a significant improvement in hard- and soft-tissue measurements. However, in the OG, there was significant lingual inclination of the lower incisor but only a small change in the IA/PAMD. In the surgical group, the IMPA was close to 90° after treatment, but the IA/PAMD significantly increased. In orthodontic camouflage, the lower anterior teeth were significantly moved lingually with a better root-bone relationship. However, this relationship deteriorated in some surgical patients. Therefore, it is important to conduct cephalometric or cone-beam computed tomography examinations during preoperative orthodontics to identify and prevent possible periodontal risks.
使用传统的头颅测量法 IMPA 和新提出的 IA/PAMD(下切牙长轴(IA)与下颌齿槽主轴(PAMD)之间的夹角)来确定正畸伪装和正颌外科手术之间的差异。 该研究包括正畸伪装组(OG)和正畸-正颌外科手术组(SG)各 40 个病例。比较了两组患者治疗前后 IMPA 和 IA/PAMD 的差异。分析了 IA/PAMD 增幅最高和最低的 10 个病例的 T0 头侧测量图像,以确定与术前正畸治疗期间下切牙过度补偿风险较高相关的特征。 OG 和 SG 在硬组织和软组织测量方面都有显著改善。然而,在OG组中,下切牙的舌侧倾斜明显,但IA/PAMD的变化却很小。在手术组中,治疗后IMPA接近90°,但IA/PAMD明显增加。 在正畸伪装中,下前牙明显向舌侧移动,牙根与牙槽骨的关系得到改善。但在一些手术患者中,这种关系有所恶化。因此,在术前正畸时进行头颅测量或锥形束计算机断层扫描检查对于识别和预防可能的牙周风险非常重要。
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引用次数: 0
Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption in rats 抑制 12/15 脂氧合酶可减少正畸诱导的大鼠牙根吸收
Pub Date : 2024-05-01 DOI: 10.2319/103123-730.1
Yukako Nashiro-Oyakawa, Y. Hotokezaka, H. Hotokezaka, Takeshi Moriishi, Mariko Funaki-Dohi, Yosuke Iuchi, Mizuki Ohama, Y. Morita, Noriaki Yoshida
To investigate whether the inhibition of 12/15-lipoxygenase (12/15-LOX), one of the core enzymes of the arachidonic acid cascade, suppresses orthodontically induced root resorption (OIRR), and examine the involvement of the hyaline degeneration of periodontal ligament cells and odontoclast differentiation. The left maxillary first molars of 10-week-old male Wistar rats were moved mesially for 14 days using a closed-coil spring (25 cN) inserted between the first molar and incisor. The rats were intraperitoneally administered with a 12/15-LOX specific inhibitor (ML-351; 0.05 mmol/kg) daily in the experimental group or vehicle (dimethyl sulfoxide) in the control group. Tooth movement was measured using microcomputed tomography on day 14. The appearance of OIRR, hyaline degeneration, osteoclasts, and odontoclasts was evaluated via histological analysis. Immunohistochemical staining for receptor-activated NF-kB ligand (RANKL) and osteoprotegerin was performed. OIRR observed on day 14 in the control group was strongly suppressed by ML-351 treatment. Hyaline degeneration observed on the compression side on day 3 and the appearance of osteoclasts and odontoclasts on days 3 and 14 were significantly suppressed by ML-351. RANKL expression on day 3 was significantly suppressed by ML-351. These key processes in OIRR were substantially suppressed by ML-351 treatment. Inhibition of 12/15-LOX reduced OIRR by suppressing hyaline degeneration and subsequent odontoclast differentiation.
研究花生四烯酸级联反应的核心酶之一 12/15 脂氧合酶(12/15-LOX)的抑制作用是否能抑制正畸诱导的牙根吸收(OIRR),并探讨牙周韧带细胞透明变性和牙髓分化的参与作用。 使用插入第一臼齿和切牙之间的闭合卷簧(25 cN),将 10 周大雄性 Wistar 大鼠的左上颌第一臼齿向中线移动 14 天。实验组大鼠每天腹腔注射 12/15-LOX 特异性抑制剂(ML-351;0.05 mmol/kg),对照组大鼠每天腹腔注射载体(二甲亚砜)。第14天使用显微计算机断层扫描测量牙齿移动情况。通过组织学分析评估 OIRR、透明变性、破骨细胞和牙髓细胞的外观。对受体激活的 NF-kB 配体(RANKL)和骨保护蛋白进行了免疫组化染色。 对照组在第 14 天观察到的 OIRR 被 ML-351 治疗强烈抑制。ML-351 能显著抑制第 3 天在受压侧观察到的透明变性,以及第 3 天和第 14 天出现的破骨细胞和破牙细胞。ML-351 还显著抑制了第 3 天 RANKL 的表达。ML-351 的处理大大抑制了 OIRR 的这些关键过程。 抑制 12/15-LOX 可抑制透明变性和随后的牙髓分化,从而减少 OIRR。
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引用次数: 0
Effects of eruption guidance appliance in the early treatment of Class III malocclusion 萌出引导矫治器在早期治疗 III 类错牙合畸形中的效果
Pub Date : 2024-02-29 DOI: 10.2319/071223-488
Gonzalo Velásquez, A. Aliaga–Del Castillo, M. Valerio, O. Maranhão, F. Miranda, G. Janson
To evaluate the dentoskeletal effects and effectiveness of the eruption guidance appliance in Class III patients in the mixed dentition. The experimental group comprised 22 patients with Class III malocclusion and anterior cross-bite (12 males, 10 females, mean age 7.63 ± 0.96 years) treated with the eruption guidance appliance over a mean period of 1.72 ± 0.48 years. The control group comprised 22 untreated subjects (12 males, 10 females, mean age 7.21 ± 0.60 years) with Class III malocclusion. Lateral cephalometric radiographs were obtained at pretreatment (T1) and posttreatment (T2). Intergroup comparisons were performed with Mann-Whitney and t-tests (P < .05). In the experimental and control groups, the anteroposterior relationship between the maxilla and mandible (ANB angle) remained stable during the treatment period (T1 to T2). The mandibular plane angle decreased in the experimental group and increased in the control group. In the experimental group, the lower anterior face height increase and maxillary molar vertical development were significantly smaller compared to controls. Positive overjet was achieved in 54% of the experimental group. The eruption guidance appliance produced no change in the skeletal anteroposterior relationship. The anterior cross-bite/edge-to-edge relationship was corrected in only about half of the treated subjects.
评估萌出引导矫治器对混合牙列 III 类患者的牙骨骼影响和有效性。 实验组包括 22 名 III 类错牙合畸形和前方交叉咬合患者(男性 12 人,女性 10 人,平均年龄为 7.63 ± 0.96 岁),他们接受了平均为期 1.72 ± 0.48 年的萌出引导矫治器治疗。对照组包括 22 名未经治疗的 III 类错牙合畸形患者(12 名男性,10 名女性,平均年龄为 7.21 ± 0.60 岁)。分别在治疗前(T1)和治疗后(T2)拍摄头侧X光片。组间比较采用曼-惠特尼检验和 t 检验(P < .05)。 在实验组和对照组中,上颌骨和下颌骨的前后关系(ANB 角)在治疗期间(T1 至 T2)保持稳定。实验组的下颌平面角度减小,对照组的下颌平面角度增大。与对照组相比,实验组的下前牙面高度增加和上颌臼齿垂直发育明显较小。54%的实验组实现了正过咬合。 萌出引导矫治器没有改变骨骼的前后关系。只有大约一半的治疗对象的前交叉咬合/边缘对边缘关系得到了矫正。
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引用次数: 0
Academic Orthodontic Opportunities 学术正畸机会
Pub Date : 2024-02-21 DOI: 10.2319/1945-7103-94.2.260
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引用次数: 0
Long-term skeletodental changes with early and late treatment using modified C-palatal plates in hyperdivergent Class II adolescents 使用改良 C 型腭板对发育过度迟缓的 II 类青少年进行早期和晚期治疗后的长期骨骼牙齿变化
Pub Date : 2024-01-16 DOI: 10.2319/081123-556.1
Jaehyun Kim, Nam-Ki Lee, Y. Kook, Yoonji Kim, Chong Ook Park, Alex Hung Kuo Chou, Sung-Hoon Han, Jae Hyun Park
To compare skeletodental changes between early and late treatment groups using modified C-palatal plates (MCPP) and long-term retention outcomes in hyperdivergent Class II adolescents. Seventy-one hyperdivergent Class II patients were divided into four groups according to treatment modality and treatment timing: group 1, early treatment with MCPP (n = 16; 9.9 ± 0.9 years); group 2, late treatment with MCPP (n = 19; 12.3 ± 0.8 years); group 3, early treatment with headgear (HG; n = 18; 9.6 ± 0.8 years); and group 4, late treatment with HG (n = 18; 12.1 ± 1.2 years). Lateral cephalograms were taken and skeletal and dental variables were measured. For statistical analysis, paired t-tests, independent t-tests, and multiple regression were performed. The early MCPP group showed a more significant decrease in mandibular plane angle than the late MCPP group did, and vertical control was more efficient in the early group than in the late group. In the MCPP groups, both FMA and SN-GoGn were increased with late treatment but decreased with early treatment, and the difference was statistically significant (P < .01). The early-treatment MCPP group had a significant decrease in SN-GoGn of 0.6° compared with an increase of 1.7° in the early treatment HG group (P < .01). Posttreatment stability of both the early and late MCPP groups was maintained in long-term retention. Early MCPP showed more significant vertical control than late MCPP. However, there was no difference in long-term stability between early and late groups.
目的:比较使用改良C腭板(MCPP)的早期和晚期治疗组之间的骨骼牙齿变化,以及过度分化II类青少年的长期保持效果。 根据治疗方式和治疗时间,将 71 名高分化 II 类患者分为四组:第一组,使用 MCPP 早期治疗(n = 16;9.9 ± 0.9 岁);第二组,使用 MCPP 晚期治疗(n = 19;12.3 ± 0.8 岁);第三组,使用头架(HG;n = 18;9.6 ± 0.8 岁)早期治疗;第四组,使用 HG 晚期治疗(n = 18;12.1 ± 1.2 岁)。拍摄了侧位头影,并测量了骨骼和牙齿变量。统计分析采用配对 t 检验、独立 t 检验和多元回归。 与晚期 MCPP 组相比,早期 MCPP 组的下颌平面角度下降更为明显,而且早期组的垂直控制比晚期组更为有效。在 MCPP 组中,FMA 和 SN-GoGn 在晚期治疗时均有所增加,而在早期治疗时则有所减少,差异有统计学意义(P < .01)。早期治疗的 MCPP 组的 SN-GoGn 显著下降了 0.6°,而早期治疗的 HG 组则上升了 1.7°(P < .01)。早期和晚期 MCPP 组治疗后的稳定性在长期保持中均得以保持。 早期 MCPP 比晚期 MCPP 显示出更明显的垂直控制。但是,早期组和晚期组在长期稳定性方面没有差异。
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引用次数: 0
Efficacy of an experimental gaseous ozone-based sterilization method for clear aligners 基于气态臭氧的透明矫治器消毒实验方法的功效
Pub Date : 2024-01-03 DOI: 10.2319/061623-421.1
Fabiana Nicita, Massimo Calapaj, S. Alibrandi, L. Donato, Emidio Aquilio, R. D’Angelo, A. Sidoti
To assess effectiveness of an experimental sterilization method based on the exposure of an O3/O2 gas mixture directly inside the packaging for clear aligners. Fifty samples consisting of pieces of polyethylene terephthalate glycol (PET-G) aligners were contaminated by manual handling and subsequently divided into different groups (n = 30 for exposure to O3/O2 gas at different times, n = 10 for positive control with 2% chlorhexidine digluconate, n = 10 for negative control). The measurement of optical densities (OD) of the initial and final microbial cultures was recorded for all groups. Kruskal-Wallis test was used for differences between groups while Wilcoxon test was used to compare initial and final OD values within groups. Statistical significance was set at P < .05. Comparison within the groups showed statistically significant differences for exposure to the gaseous mixture (72 hours), for positive and negative controls. Other significant differences were found in the multiple comparisons between the application of gaseous ozone (48 hours and 72 hours) and the negative control. The direct exposure of gaseous ozone on the aligners inside their packaging showed microbicidal capacity at 72 hours, which was equivalent to the positive control with immersion in chlorhexidine digluconate. This innovative sterilization procedure could be considered in the final manufacturing processes of clear aligners to eliminate the potentially pathogenic microorganisms that are deposited on surfaces of these orthodontic devices.
评估直接在透明对准器包装内接触 O3/O2 混合气体的实验性消毒方法的有效性。 手工操作污染了由聚对苯二甲酸乙二醇酯(PET-G)对准器碎片组成的 50 个样品,随后将其分成不同的组(n = 30 在不同时间暴露于 O3/O2 气体,n = 10 用 2% 洗必泰二氯葡萄糖酸盐进行阳性对照,n = 10 进行阴性对照)。记录所有组的初始和最终微生物培养物的光密度(OD)。组间差异采用 Kruskal-Wallis 检验,组内初始和最终 OD 值的比较采用 Wilcoxon 检验。统计显著性以 P < .05 为标准。 组内比较显示,暴露于气态混合物(72 小时)、阳性对照组和阴性对照组的差异具有统计学意义。气态臭氧应用(48 小时和 72 小时)与阴性对照之间的多重比较也发现了其他显着差异。 气态臭氧直接照射包装内的矫治器在72小时后显示出杀菌能力,与浸泡在洗必泰二氯葡萄糖酸盐中的阳性对照组相当。在透明矫治器的最终生产过程中,可以考虑采用这种创新的杀菌程序,以消除沉积在这些矫治器表面的潜在病原微生物。
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引用次数: 0
Assessment of maximal inspiratory and expiratory pressures in skeletal Class II patients with different growth patterns 评估不同生长模式的骨骼 II 级患者的最大吸气和呼气压力
Pub Date : 2023-12-28 DOI: 10.2319/071723-496.1
Hita Rangarajan, I. I. Ayub, Sridevi Padmanabhan
To evaluate maximal inspiratory (MIP) and expiratory (MEP) pressures, which are reflective of respiratory muscle strength, in skeletal Class II patients with different growth patterns (horizontal, average, and vertical) and to correlate those with airway dimension. Patients with a Class II skeletal base seeking orthodontic treatment were assigned to the following groups: average, horizontal, and vertical growth pattern. The control group (n = 14) comprised patients with a Class I skeletal base and average growth pattern. Airway dimensions were obtained using cone-beam computed tomography scans, and a spirometer with a pressure transducer was used for assessment of MIP and MEP. Routine spirometry for assessment of lung function was also performed. No significant differences were found in maximal inspiratory and expiratory pressures for the study groups in comparison with the control group. Class I patients had significantly greater oropharyngeal and nasopharyngeal airway volumes compared with the study groups. No significant difference in minimal cross-section area of the airway was observed among groups. A weak positive correlation between maximal inspiratory pressure and airway volume was observed. Although Class I patients displayed significantly greater oropharyngeal and nasopharyngeal airway volumes, there was no significant difference in respiratory muscle strength or airway function between Class II patients with different growth patterns and the Class I control group. The findings underscore the significance of exploring factors beyond craniofacial growth patterns that may contribute to sleep-related breathing disorders.
目的:评估不同生长模式(水平生长模式、平均生长模式和垂直生长模式)的骨骼Ⅱ级患者的最大吸气压力(MIP)和呼气压力(MEP),并将其与气道尺寸相关联。 将寻求正畸治疗的骨骼基础为 II 类的患者分为以下几组:平均生长模式组、水平生长模式组和垂直生长模式组。对照组(n = 14)由骨骼基底为 I 类且生长模式为平均生长模式的患者组成。使用锥形束计算机断层扫描获得气道尺寸,并使用带压力传感器的肺活量计评估 MIP 和 MEP。此外,还进行了常规肺活量测定以评估肺功能。 研究组的最大吸气压和呼气压与对照组相比无明显差异。与研究组相比,I 类患者的口咽和鼻咽气道容积明显更大。研究组与对照组在气道最小横截面积方面无明显差异。最大吸气压力与气道容积之间呈弱正相关。 虽然 I 类患者的口咽和鼻咽气道容积明显更大,但具有不同生长模式的 II 类患者与 I 类对照组在呼吸肌强度或气道功能方面没有明显差异。这些发现强调了研究颅面生长模式以外可能导致睡眠相关呼吸障碍的因素的重要性。
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引用次数: 0
Reviewers for The Angle Orthodontist for 2023 2023 年《角度矫正学》的评论者
Pub Date : 2023-12-20 DOI: 10.2319/1945-7103-94.1.138
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引用次数: 0
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The Angle Orthodontist
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