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Testicular ultrasound measurement of testicular volume and epididymis diameters: Prediction of semen quality in a prospective study 睾丸超声测量睾丸体积和附睾直径:前瞻性研究中的精液质量预测
Pub Date : 2024-06-03 DOI: 10.1556/1647.2024.00184
Norbert Pásztor, D. Veréb, I. Király, Z. Kincses, András Palkó, Gábor Németh, Zoltán Bajory, Z. Fejes
To identify the most predictive ultrasound parameters for the assessment of male infertility by a multiparametric study.A total of 64 males were recruited in the study group and 14 men in the control group. At first, grey-scale and color and Power Doppler ultrasonographic imaging was used to analyze testicular morphological characteristics and detect intratesticular abnormalities. Various ultrasound parameters of B-mode US and strain-elastography were related to total sperm count (TSC).The prevalence of varicocele was not significant (P = 0.33), though presented a 2.53-fold odds ratio The strain ratios of both testes, the volume of the left testis and the size of the left appendix were most associated with the results of semen analysis according to a Variable Importance in the Projection (VIP) score of >1. The first latent variable from the PLS analysis explained a significant amount of variance in TSC, concentration, and motility parameters (P < 0.0002) and showed that bilateral strain ratio, the size of the testis, and the volume of left appendix were the most significant US predictors of the pathological semen and sperm cell features.Our results showed that B-mode US with strain elastography is among more sensitive US approaches in evaluating male fertility.
通过多参数研究确定对男性不育症评估最具预测性的超声参数。研究组共招募了 64 名男性,对照组招募了 14 名男性。研究组共有 64 名男性,对照组有 14 名男性。研究组首先使用灰阶、彩色和动力多普勒超声成像技术分析睾丸形态特征,并检测睾丸内异常。双侧睾丸的应变比、左侧睾丸的体积和左侧阑尾的大小与精液分析结果的相关性最大,根据投影中的变量重要性(VIP)评分>1。PLS分析的第一个潜变量解释了TSC、浓度和活力参数的显著变异量(P < 0.0002),并显示双侧应变比、睾丸体积和左盲肠体积是病理精液和精子细胞特征最显著的US预测因子。
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引用次数: 0
What patient positioning in chest X-ray is still acceptable? – An empirical study on thresholding quality metrics 在胸部 X 光检查中,什么样的患者定位仍可接受?- 关于阈值质量指标的实证研究
Pub Date : 2024-05-08 DOI: 10.1556/1647.2024.00187
Jens von Berg, Kenneth F. M. Hergaarden, Max Englmaier, Daniela Pfeiffer, N. Wieberneit, Sven Krönke-Hille, T. Harder, André Gooßen, Daniel Bystrov, Matthias Brueck, Stewart Young, Hildo. J. Lamb
Issues in patient positioning during chest X-ray (CXR) acquisition impair diagnostic quality and potentially increase radiation dose. Automated quality assessment was proposed to address this. Our objective is to determine thresholds on some quality control metrics following international guidelines, that represent expert knowledge and can be applied in a comprehensible and explainable AI approach for such an automatic quality assessment.An AI-method estimating collimation distance to the ribcage, balancing between both clavicle heads, and number of ribs above the diaphragm as metrics for collimation, rotation, and inhalation quality was applied on 64,315 posteroanterior CXR images from a public dataset (ChestX-ray8). From this set 920 CXR images were sampled and manually annotated to gain additional trusted reference metrics. Seven readers from different institutions then classified the acquisition quality of these images independently into okay, inadequate, or unacceptable following the criteria of international guidelines. Optimal thresholds on the metrics were determined to reproduce these classes using the metrics only.A fair to moderate agreement between the experts was found. When disregarding all inadequate rates a classification on the metrics was able to separate okay rated cases from unacceptable cases for collimation (AUC 0.97), rotation (AUC = 0.93) and inhalation (AUC = 0.97).Suitable thresholds were determined to reproduce expert opinions in the assessment of the most important quality criteria in CXR acquisition. These thresholds were finally applied on the AI-method's estimates to automatically classify image acquisition quality comprehensibly and according to the guidelines.
胸部 X 光(CXR)采集过程中患者定位的问题会影响诊断质量,并可能增加辐射剂量。为解决这一问题,我们提出了自动质量评估方法。我们的目标是根据国际指南确定一些质量控制指标的阈值,这些阈值代表了专家知识,可应用于自动质量评估的可理解和可解释的人工智能方法中。我们在公共数据集(ChestX-ray8)中的 64,315 张后正位 CXR 图像上应用了一种人工智能方法,该方法将到肋骨的准直距离、两个锁骨头之间的平衡以及横膈膜上方的肋骨数量作为准直、旋转和吸入质量的指标。从这组图像中抽取了 920 张 CXR 图像并进行了人工标注,以获得更多可信的参考指标。然后,来自不同机构的七位读者按照国际指南的标准,将这些图像的采集质量独立分为合格、不合格或不可接受。专家们的意见相当一致。在不考虑所有不合格率的情况下,指标分类能够将准直(AUC 0.97)、旋转(AUC = 0.93)和吸入(AUC = 0.97)方面的合格病例与不合格病例区分开来。最后将这些阈值应用于人工智能方法的估计值,以便根据指南对图像采集质量进行自动分类。
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引用次数: 0
Pre-hospital ultrasonography screening for biliary disease in remote settings 偏远地区胆道疾病的院前超声波筛查
Pub Date : 2024-03-12 DOI: 10.1556/1647.2024.00181
Sérgio Miravent, Cármen Jimenez, Manuel Lobo, Teresa Figueiredo, R. P. P. de Almeida
Screening ultrasound, including Point of Care Ultrasonography (POCUS), is widely utilized for rapid clinical guidance in diverse healthcare settings. In this case report, a 34-year-old male with recurrent biliary colic symptoms underwent a Basic Emergency Service ultrasound, revealing a 13 mm gallbladder calculus and signs of inflammation, and was promptly referred to the hospital for further evaluation and treatment. Medical specialist confirmation at the hospital underscored the significance of early detection through POCUS. Despite inconclusive laboratory results, the detailed ultrasound assessment provided a comprehensive understanding, emphasizing the tool's value in averting complications. Thus, screening ultrasound played a pivotal role in justifying the hospital referral, showcasing its vital role in healthcare, especially in resource-limited settings. The judicious use of POCUS can lead to superior outcomes, avoiding unnecessary referrals for non-emergent cases.
超声波筛查,包括护理点超声波检查(POCUS),被广泛用于不同医疗机构的快速临床指导。在本病例报告中,一名 34 岁的男性因反复出现胆绞痛症状而接受了基础急诊超声检查,结果显示其胆囊内有 13 毫米的结石并伴有炎症迹象,患者被迅速转诊至医院接受进一步评估和治疗。医院的医学专家证实了通过 POCUS 进行早期检测的重要性。尽管化验结果没有定论,但详细的超声评估提供了全面的了解,强调了该工具在避免并发症方面的价值。因此,超声筛查在证明医院转诊合理性方面发挥了关键作用,展示了其在医疗保健中的重要作用,尤其是在资源有限的环境中。合理使用 POCUS 可带来卓越的疗效,避免非急诊病例不必要的转诊。
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引用次数: 0
Evaluation of the cardiopulmonary size on slot-scanning full-spine radiographs 通过槽扫描全脊柱 X 光片评估心肺大小
Pub Date : 2024-03-06 DOI: 10.1556/1647.2024.00180
Pershalia Naidoo, B. Botz
Slot-scanning EOS radiography is increasingly utilised in skeletal imaging. It has been shown that EOS often reveals significant incidental findings including cardiopulmonary abnormalities. Furthermore, the slot-scanning image acquisition of EOS can substantially influence depiction of cardiac morphology, which can be confusing for those unfamiliar with the technique.We aimed to explore the relationship between the depicted cardiac anatomy EOS and chest x-ray, by analysis of the differences in the measurements of the cardiothoracic ratio in 52 patients who had an erect, postero-anterior chest radiograph in deep inspiration, with less than a year difference to the EOS spine radiograph. Internal chest and cardiac diameter were measured, and the cardiothoracic ratio (CTR) was calculated as a surrogate marker for gross cardiac size.We have found that EOS consistently yields a lower internal chest diameter, and as a result higher CTR (P < 0.0001). However CTR measured on EOS and plain radiograph show strong correlation (P < 0.0001). Bland-Altman plots also revealed a consistently higher CTR on EOS, and a high intra-individual variability of cardiac and chest diameters on EOS vs. x-ray. CTR measured on EOS showed correlation with age (P < 0.05).We show that the CTR on EOS radiographs is consistently higher compared to the chest radiography, and while cardiac diameter shows only minimal difference, chest diameter measured on EOS is markedly lower. This should be considered by those reporting spine EOS imaging to avoid overcalling incidental cardiomegaly.
狭缝扫描 EOS 放射摄影越来越多地用于骨骼成像。研究表明,EOS 经常能发现包括心肺异常在内的重大偶然发现。此外,EOS 的槽扫描图像采集会严重影响心脏形态的描述,这可能会让不熟悉该技术的人感到困惑。我们的目的是通过分析 52 名患者在深吸气时直立、后正位胸部 X 光片与 EOS 脊柱 X 光片之间心胸比例测量值的差异,来探讨 EOS 和胸部 X 光片所描述的心脏解剖结构之间的关系。我们发现,EOS 所测得的胸腔内径较小,因此心胸比也较高(P < 0.0001)。然而,EOS 和普通 X 光片测量的 CTR 显示出很强的相关性(P < 0.0001)。Bland-Altman 图还显示,EOS 的 CTR 始终较高,而 EOS 与 X 光片相比,心脏和胸部直径的个体内变异性较高。我们的研究表明,EOS X 光片上的 CTR 始终比胸部 X 光片上的高,虽然心脏直径显示的差异很小,但 EOS X 光片上测量的胸部直径却明显较低。报告脊柱 EOS 成像的人员应考虑到这一点,以避免过度报告偶然的心脏肿大。
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引用次数: 0
Inter-reader reproducibility of a radiographic grading system for usual interstitial pneumonitis validates its use as a surrogate endpoint in clinical trials 常见间质性肺炎放射学分级系统的读片者间重复性验证了其在临床试验中作为替代终点的有效性
Pub Date : 2024-03-06 DOI: 10.1556/1647.2024.00190
K. Capaccione, Hong Ma, L. Luk, Mary M. Salvatore
The primary purpose of this study was to assess the interreader reliability of a grading system for UIP based on the quantification of normal lung. This grading system considers each of the following lung regions: right upper and middle lobes, right lower lobe, left upper lobe, and left lower lobe. Each is assigned a grade based on the following: 0: 0% normal lung; 1: 1–49% normal lung; 2: 50–74% normal lung; 3: 75–89% normal lung; 4: 90–99% normal lung; 5: 100% normal lung. The secondary purpose was to compare the grades rendered by non-cardiothoracic subspecialty trained radiologists to grades established by cardiothoracic radiologists, which were considered the gold standard.Chest CT images of patients were obtained by searching the radiology record system for the terms “usual interstitial pneumonia” and “UIP”. Each case was confirmed by radiologist review; pathology was not assessed given the small fraction of cases that underwent biopsy due to the high risk of complications in patients with fibrotic lung disease. Two cardiothoracic radiologists evaluated each CT and reached a consensus grade. Two different radiologists who were not subspecialty trained in cardiothoracic radiology independently graded each case. Spearman correlation analysis was performed to compare the two reader's grades as well as each reader's grade independently to the gold standard score.Our analysis demonstrated a strongly positive statistically significant interreader correlation coefficient (RS) = 0.7062, P < 0.001. Our analysis of each reader compared to the gold standard demonstrated an Rs = 0.77559, P < 0.001 and an RS = 0.69958, P < 0.001 for readers 1 and 2, respectively, both representing statistically significant strongly positive correlations.These results demonstrate strong interreader reproducibility and show that radiologists without subspecialty training in cardiothoracic radiology render grades that correlate strongly with those given by cardiothoracic radiologists. These findings support the use of this grading system for UIP both to monitor clinical progression and as a surrogate endpoint for antifibrotic drug trials.
本研究的主要目的是评估基于正常肺部量化的 UIP 分级系统的读片机间可靠性。该分级系统考虑了以下每个肺部区域:右上叶和中叶、右下叶、左上叶和左下叶。每个区域根据以下标准划分等级:0:0% 正常肺;1:1-49% 正常肺;2:50-74% 正常肺;3:75-89% 正常肺;4:90-99% 正常肺;5:100% 正常肺。次要目的是将非心胸亚专业放射科医生的分级与心胸放射科医生确定的分级进行比较,后者被认为是金标准。患者的胸部 CT 图像是通过在放射科记录系统中搜索 "常见间质性肺炎 "和 "UIP "这两个术语获得的。每个病例均由放射科医生审查确认;由于纤维化肺病患者出现并发症的风险较高,只有一小部分病例进行了活检,因此没有进行病理评估。两名心胸放射科医生对每张 CT 进行评估,并达成一致的分级。两名未接受过心胸外科放射学亚专业培训的不同放射科医生对每个病例进行独立分级。我们的分析表明,读片者之间的相关系数 (RS) = 0.7062,P < 0.001。我们对每位读者与金标准的比较分析表明,读者 1 和读者 2 的 Rs = 0.77559,P < 0.001,RS = 0.69958,P < 0.001,两者均为统计学意义上的强正相关。这些结果表明读者间具有很强的可重复性,并表明未接受过心胸外科放射学亚专业培训的放射科医生给出的分级与心胸外科放射科医生给出的分级具有很强的相关性。这些研究结果支持使用这种 UIP 分级系统监测临床进展,并将其作为抗纤维化药物试验的替代终点。
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引用次数: 0
Spontaneous nontraumatic rupture of the biceps tendon 肱二头肌肌腱自发性非创伤性断裂
Pub Date : 2024-02-20 DOI: 10.1556/1647.2024.00185
Uddalok Das
The biceps is one of the most important muscles of the flexor compartment of the arm. Recently there has been an increase in the global reported incidence of biceps tendon rupture worldwide. Generally, tears are seen in the elderly population and are precipitated due to underlying risk factors. Diagnosis is done with a combination of clinical findings and ultrasonography. We report a case of a 60-year-old female without any underlying risk factors who presented with nontraumatic spontaneous rupture of the right biceps tendon.
肱二头肌是手臂屈肌区最重要的肌肉之一。最近,全球报告的肱二头肌肌腱断裂发病率有所上升。一般来说,肱二头肌肌腱断裂多见于老年人群,是由于潜在的危险因素引起的。诊断需要结合临床表现和超声波检查。我们报告了一例 60 岁女性右肱二头肌腱非创伤性自发性断裂的病例,患者无任何潜在危险因素。
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引用次数: 0
Artificial intelligence-based quantification of COVID-19 pneumonia burden using chest CT 基于人工智能的胸部 CT COVID-19 肺炎负荷量化方法
Pub Date : 2024-02-20 DOI: 10.1556/1647.2024.00167
C. Nardocci, Judit Simon, B. Budai
During the coronavirus disease 2019 (COVID-19) pandemic, artificial intelligence (AI) based software on chest computed tomography (CT) imaging has proven to have a valuable role in accelerating diagnosis and screening. The proposed AI-based tools proved to be rapid and reproducible techniques to guide patient management and treatment protocols. Although no specific guidelines exist, CT-imaging and clinical features are used for patient staging. To shed light on the role of AI techniques that have been developed in fighting COVID-19, in this review, studies investigating the usage of commonly used AI models on chest CT imaging for disease quantification and prognostication are collected.
在冠状病毒病 2019(COVID-19)大流行期间,基于人工智能(AI)的胸部计算机断层扫描(CT)成像软件被证明在加速诊断和筛查方面发挥了重要作用。事实证明,所提出的基于人工智能的工具是指导患者管理和治疗方案的快速、可重复的技术。虽然没有具体的指南,但 CT 成像和临床特征被用于对患者进行分期。为了阐明在与 COVID-19 斗争中开发的人工智能技术的作用,本综述收集了有关在胸部 CT 成像中使用常用人工智能模型进行疾病量化和预后分析的研究。
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引用次数: 0
期刊
Imaging
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