Pub Date : 2024-03-02DOI: 10.53555/jptcp.v31i3.4706
M. Tanveer, Ejaz Asghar, Umar Tanveer, Nadeem Roy, Asifa Zeba, M. Z. H. Khan, Nayab Tanveer, Fouzia Abdul Razzaq
{"title":"INTRAPERSONAL LEVEL UNHEALTHY BEHAVIORS (SMOKING, DRINKING ALCOHOL, AND TOBACCO USE) AND THEIR ASSOCIATION WITH BODY MASS INDEX AMONG SCHOOL-AGED CHILDREN AND ADOLESCENTS IN PAKISTAN","authors":"M. Tanveer, Ejaz Asghar, Umar Tanveer, Nadeem Roy, Asifa Zeba, M. Z. H. Khan, Nayab Tanveer, Fouzia Abdul Razzaq","doi":"10.53555/jptcp.v31i3.4706","DOIUrl":"https://doi.org/10.53555/jptcp.v31i3.4706","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"36 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140081609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-24DOI: 10.53555/jptcp.v31i2.4622
Dara Jamali, Fasiha Mazhar, Arzu Jadoon
Introduction: Although the prevalence of gastroesophageal reflux disease (GERD) in intensive care units is still unknown, the condition is on the rise all over the world. Patients in critical condition are especially susceptible to gastroesophageal reflux disease (GERD) because of the many procedures and underlying illnesses they undergo. Pepsin levels in oral secretions, ambulatory monitoring, and pH measurement are among procedures that can be utilized in the diagnostic process. The most popular treatment methods consist of adjusting one's lifestyle and using medicine, mainly proton pump inhibitors (PPIs). Methodology: An analysis of data collected from 96 critically sick patients who were getting acid-lowering medication was carried out in retrospective research that was carried out at a tertiary care hospital in AJK, Pakistan between June and December 2023. Results: Most patients were being treated in medical intensive care units (MICU), and the medications that were prescribed the most frequently were omeprazole and esomeprazole. Omeprazole and antacids were the primary maintenance medications that were administered at the time of discharge. Patients who were diagnosed with gastroesophageal reflux disease (GERD) and those who were undergoing mechanical ventilation made up a sizeable share, with most of them receiving intravenous proton pump inhibitors (PPIs). Both potassium-competitive acid blockers and omeprazole were shown to have equivalent levels of treatment efficacy, according to the findings. Conclusion: Most of trials in past have established esomeprazole being highlighted as having superiority in certain studies. On the other hand, newer possibilities such as GABA-B agonist baclofen and P-CABs offer potential lines of investigation. Even though developing medicines require more exploration for routine management, intravenous proton pump inhibitors (PPIs) continue to be the primary emergency treatment for gastroesophageal reflux disease (GERD) in critical care.
{"title":"THERAPEUTIC APPROACHES FOR ACID REDUCTION IN PATIENTS ADMITTED TO INTENSIVE CARE UNITS WITH A HISTORY OF GASTROESOPHAGEAL REFLUX DISEASE AT A TERTIARY CARE HOSPITAL IN PAKISTAN.","authors":"Dara Jamali, Fasiha Mazhar, Arzu Jadoon","doi":"10.53555/jptcp.v31i2.4622","DOIUrl":"https://doi.org/10.53555/jptcp.v31i2.4622","url":null,"abstract":"Introduction: Although the prevalence of gastroesophageal reflux disease (GERD) in intensive care units is still unknown, the condition is on the rise all over the world. Patients in critical condition are especially susceptible to gastroesophageal reflux disease (GERD) because of the many procedures and underlying illnesses they undergo. Pepsin levels in oral secretions, ambulatory monitoring, and pH measurement are among procedures that can be utilized in the diagnostic process. The most popular treatment methods consist of adjusting one's lifestyle and using medicine, mainly proton pump inhibitors (PPIs). Methodology: An analysis of data collected from 96 critically sick patients who were getting acid-lowering medication was carried out in retrospective research that was carried out at a tertiary care hospital in AJK, Pakistan between June and December 2023. Results: Most patients were being treated in medical intensive care units (MICU), and the medications that were prescribed the most frequently were omeprazole and esomeprazole. Omeprazole and antacids were the primary maintenance medications that were administered at the time of discharge. Patients who were diagnosed with gastroesophageal reflux disease (GERD) and those who were undergoing mechanical ventilation made up a sizeable share, with most of them receiving intravenous proton pump inhibitors (PPIs). Both potassium-competitive acid blockers and omeprazole were shown to have equivalent levels of treatment efficacy, according to the findings. Conclusion: Most of trials in past have established esomeprazole being highlighted as having superiority in certain studies. On the other hand, newer possibilities such as GABA-B agonist baclofen and P-CABs offer potential lines of investigation. Even though developing medicines require more exploration for routine management, intravenous proton pump inhibitors (PPIs) continue to be the primary emergency treatment for gastroesophageal reflux disease (GERD) in critical care.","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"94 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140433683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-21DOI: 10.53555/jptcp.v30i2.4683
Ahmed Othman Almailabi, Ali Mohammed Nassir Alshaikhi, May Motea Sado Sahyoun, M. M. Algarni, Ali Hebni Ali Alshehri, Wael Seddiq Mosa Elagi, AbdulKarim Matar Aun Alsulami, Iprahim Ahmed Alzahrani, Ahmad mohammad Alghamdi, Yasser ali Alharbi, Faisal matar Al anazi anazi
The issue of antimicrobial medication resistance is a significant global concern. Drug discovery plays a crucial role in addressing present treatment gaps and enhancing established therapeutic methods. However, due to the extensive research duration and substantial expenses involved in introducing novel drugs to the market, focusing on the development of new drugs that target drug-resistant microbes with harmful effects may not be the most optimal approach. The literature was systematically evaluatesing databases to identify all relevant research published until the beginning of 2022. In order to uncover novel classes of antibiotics, there is a pressing need for the development of innovative methodologies in rational design and screening-based approaches. The advancement of efficient molecular methodologies for the identification of resistance genes, as well as the exploration of diagnostic biomarkers such as procalcitonin for the purpose of guiding the discontinuation of antibiotic treatment, holds significant value in the effort to mitigate antibiotic usage.
{"title":"AN OVERVIEW PHARMACIST'S ROLE IN PREVENTING MEASURES TOWARD ANTIBIOTIC RESISTANCE","authors":"Ahmed Othman Almailabi, Ali Mohammed Nassir Alshaikhi, May Motea Sado Sahyoun, M. M. Algarni, Ali Hebni Ali Alshehri, Wael Seddiq Mosa Elagi, AbdulKarim Matar Aun Alsulami, Iprahim Ahmed Alzahrani, Ahmad mohammad Alghamdi, Yasser ali Alharbi, Faisal matar Al anazi anazi","doi":"10.53555/jptcp.v30i2.4683","DOIUrl":"https://doi.org/10.53555/jptcp.v30i2.4683","url":null,"abstract":"The issue of antimicrobial medication resistance is a significant global concern. Drug discovery plays a crucial role in addressing present treatment gaps and enhancing established therapeutic methods. However, due to the extensive research duration and substantial expenses involved in introducing novel drugs to the market, focusing on the development of new drugs that target drug-resistant microbes with harmful effects may not be the most optimal approach. The literature was systematically evaluatesing databases to identify all relevant research published until the beginning of 2022. In order to uncover novel classes of antibiotics, there is a pressing need for the development of innovative methodologies in rational design and screening-based approaches. The advancement of efficient molecular methodologies for the identification of resistance genes, as well as the exploration of diagnostic biomarkers such as procalcitonin for the purpose of guiding the discontinuation of antibiotic treatment, holds significant value in the effort to mitigate antibiotic usage.","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140443454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-10DOI: 10.53555/jptcp.v31i1.4148
Parameshwari K, Nandini T, Naveen Chandra, Sangeetha R Gore
{"title":"ANTICONVULSANT ACTIVITY OF WOODFORDIA FRUTICOSA (L.) KURZ FLOWERS IN ANIMAL SCREENING MODELS","authors":"Parameshwari K, Nandini T, Naveen Chandra, Sangeetha R Gore","doi":"10.53555/jptcp.v31i1.4148","DOIUrl":"https://doi.org/10.53555/jptcp.v31i1.4148","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"56 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.53555/jptcp.v30i19.3681
Khalid Mehmood, Muhammad Akram, Sultan Ayaz, A. Rashid, H. M. Asif
{"title":"ANTIOXIDANT ACTIVITY AND EVALUATION OF SEVEN MEDICINAL PLANTS FOR POTENTIAL ROLE IN MANAGING OXIDATIVE STRESS IN ANEMIA","authors":"Khalid Mehmood, Muhammad Akram, Sultan Ayaz, A. Rashid, H. M. Asif","doi":"10.53555/jptcp.v30i19.3681","DOIUrl":"https://doi.org/10.53555/jptcp.v30i19.3681","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"41 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.53555/jptcp.v30i19.3649
J. Janjua, Areej Fatima, Atifa Athar, Muhammad Saleem Khan, Zia Ul Rehman, R. Javed, Tahir Abbas, Insia Zahra
{"title":"FEDERATED LEARNING FOR PREDICTION OF ENERGY CONSUMPTION IN EDGE-ENABLED SMART CITIES WITH HEALTHCARE INFRASTRUCTURE CROSSROADS","authors":"J. Janjua, Areej Fatima, Atifa Athar, Muhammad Saleem Khan, Zia Ul Rehman, R. Javed, Tahir Abbas, Insia Zahra","doi":"10.53555/jptcp.v30i19.3649","DOIUrl":"https://doi.org/10.53555/jptcp.v30i19.3649","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139183980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-30DOI: 10.53555/jptcp.v30i18.3467
Awais Ali, Uzma Manzoor, S. L. Ali, M. D. Marsool, Prasanta Kumar Parida, Ali Dheyaa Marsool, NL Swathi
{"title":"CURRENTLY TRENDING AND FUTURISTIC BIOLOGICAL MODALITIES IN THE MANAGEMENT OF DIFFERENT TYPES OF DIABETES: A COMPREHENSIVE REVIEW","authors":"Awais Ali, Uzma Manzoor, S. L. Ali, M. D. Marsool, Prasanta Kumar Parida, Ali Dheyaa Marsool, NL Swathi","doi":"10.53555/jptcp.v30i18.3467","DOIUrl":"https://doi.org/10.53555/jptcp.v30i18.3467","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OSTEOPOROSIS KAP IN KARACHI: A QUANTITATIVE CROSS-SECTIONAL STUDY","authors":"Tahmina Maqbool, Humera Ishaq, Shadab Kashif, Maheen Ali, Yamna salam, Alizah Irshad, Mathumalar Loganathan, Muhammad Shahzad Aslam","doi":"10.53555/jptcp.v30i18.3352","DOIUrl":"https://doi.org/10.53555/jptcp.v30i18.3352","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-28DOI: 10.53555/jptcp.v30i18.3549
Dr Esha Ali, Dr Zulqurnain Younas, Dr Mohammad Aslam, Dr. Nazia Mubarik
{"title":"TO DETERMINE THE OUTCOME OF HYPOSPADIAS SURGERY IN POPULATION OF AGE RANGES FROM 3 TO 20 YEARS USING HOSE SCORING.","authors":"Dr Esha Ali, Dr Zulqurnain Younas, Dr Mohammad Aslam, Dr. Nazia Mubarik","doi":"10.53555/jptcp.v30i18.3549","DOIUrl":"https://doi.org/10.53555/jptcp.v30i18.3549","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139219714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-28DOI: 10.53555/jptcp.v30i18.3523
Raja Kaminedi Rajeswari, Rahaf Mansour Almansour, Farah Nasser Alrajhi
{"title":"PAPILLON-LEFÈVRE SYNDROME IN DENTAL PEDIATRIC PATIENT: A COMPREHENSIVE REVIEW.","authors":"Raja Kaminedi Rajeswari, Rahaf Mansour Almansour, Farah Nasser Alrajhi","doi":"10.53555/jptcp.v30i18.3523","DOIUrl":"https://doi.org/10.53555/jptcp.v30i18.3523","url":null,"abstract":"","PeriodicalId":504389,"journal":{"name":"Journal of Population and Therapeutics and Clinical Pharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139222056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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