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Defining and reporting exercise intensity in interventions for older adults: a modified Delphi process 界定和报告老年人干预措施中的运动强度:改良德尔菲程序
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2024-02-02 DOI: 10.1186/s11556-024-00337-8
Bettina Wollesen, Mona Herden, Nicola Lamberti, Christoforos D. Giannaki
Many exercise studies, including older adults, do not report all relevant exercise characteristics. Especially the description of exercise intensity is missing and mostly not controlled. This leads to difficulties in interpreting study results and summarizing the evidence in systematic reviews or meta-analyses. Therefore, the aim of the present Delphi study was to gain recommendations about the categorization of exercise intensity and for the conducting and reporting of characteristics in future intervention studies with older adults by experts in exercise science and physiology. Two hundred ninety-seven international interdisciplinary participants from an EU COST action were invited to participate in three rounds of online questionnaires in April/May 2023. Up to N = 93 experts participated in each round. Round 1 included open-ended questions to solicit possible recommendations and categorizations for light, moderate, vigorous, and high intensity. In round 2, the experts rated their agreement using Likert scales (1–10) on the revealed categories and recommendations. Clusters with a higher average rating of M = 8.0 were summarized into round 3. In the final round, the results were presented for a final rating of agreement (based on a simple majority > 50%). In round 1 a total of 416 qualitative statements were provided from thirteen questions. From round 1 to round 3, a total of 38 items were excluded, with 205 items retained for the final consensus. In round three 37 participants completed the whole questionnaire. The experts showed overall agreement on the final categorizations with 6.7 to 8.8 out of 10 points on the Likert scale. They also showed broad consensus on the relevance of reporting exercise intensity and the recommendations for future conducting and reporting of study results. However, exercise types such as yoga, balance, and coordination training led to conflicting results for categorization into light or moderate. The results of the current survey can be used to classify the intensity of exercise and suggest a practical approach that can be adopted by the scientific community and applied when conducting systematic reviews and meta-analysis articles when vital and objective information regarding exercise intensity is lacking from the original article. - Experts highlight the importance of reporting exercise intensity for individualization and participant safety - International interdisciplinary participants with expertise in exercise gained a common understanding of the categorization of exercise intensity for future intervention studies with older adults. - Conflicting results for exercise types such as yoga, balance, and coordination training present categorization challenges
包括老年人在内的许多运动研究都没有报告所有相关的运动特征。尤其是对运动强度的描述缺失,而且大多没有进行控制。这给解释研究结果和总结系统综述或荟萃分析中的证据带来了困难。因此,本德尔菲研究的目的是由运动科学和生理学专家就运动强度的分类以及未来针对老年人的干预研究的开展和特征报告提出建议。来自欧盟 COST 行动的 297 名国际跨学科参与者受邀参加了 2023 年 4 月/5 月的三轮在线问卷调查。每一轮最多有 N = 93 名专家参与。第 1 轮包括开放式问题,以征求可能的建议,并对轻度、中度、剧烈和高强度进行分类。在第二轮中,专家们使用李克特量表(1-10)对所揭示的类别和建议进行评分。平均评分 M = 8.0 较高的群组被汇总到第 3 轮。在最后一轮中,专家们给出了最终的同意度(基于简单多数>50%)。在第一轮中,13 个问题共提供了 416 个定性陈述。从第一轮到第三轮,共剔除了 38 个项目,保留了 205 个项目以达成最终共识。在第三轮中,37 名参与者完成了整个问卷。专家们对最终分类的总体意见一致,利克特量表满分为 6.7 至 8.8 分(满分为 10 分)。他们还就报告运动强度的相关性以及今后开展和报告研究结果的建议达成了广泛共识。然而,瑜伽、平衡和协调训练等运动类型导致了轻度或中度运动分类结果的冲突。本次调查的结果可用于对运动强度进行分类,并提出了一种实用的方法,可供科学界采用,并在进行系统综述和荟萃分析文章时,当原始文章中缺乏有关运动强度的重要客观信息时加以应用。- 专家们强调了报告运动强度对个体化和参与者安全的重要性--具有运动专业知识的国际跨学科参与者就运动强度的分类达成了共识,以便今后对老年人进行干预研究。- 瑜伽、平衡和协调训练等运动类型的结果相互矛盾,给分类带来了挑战
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引用次数: 0
The relationship between self-perceived fatigue, muscle endurance, and circulating markers of inflammation in participants of the Copenhagen aging and Midlife Biobank (CAMB) 哥本哈根中老年生物数据库(CAMB)参与者的自我感觉疲劳、肌肉耐力和循环炎症标记物之间的关系
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2024-01-31 DOI: 10.1186/s11556-024-00336-9
Ivan Bautmans, Veerle Knoop, Ingo Beyer, Helle Bruunsgaard, Drude Molbo, Erik Lykke Mortensen, Rikke Lund
Fatigue, low muscle endurance, muscle weakness and low-grade inflammation are strongly related to frailty at higher age. When signs of self-perceived fatigue and low muscle endurance are interrelated with low-grade inflammation at midlife, they might be used as early markers for frailty. This study investigated whether the interrelationships among self-perceived fatigue, muscle endurance and inflammation can be observed at midlife. A total of 965 participants of the Copenhagen Aging and Midlife Biobank (aged 52 ± 4 years, 536 males, 426 females) were assessed for self-perceived fatigue (20-item multidimensional fatigue inventory), muscle endurance (grip work), circulating markers of inflammation (hsCRP, IL-6, IL-10, TNF-alpha and IFN-γ), daily physical activity (PAS-2), body composition (%body fat assessed by bio-impedance) and self-reported health status. Participants were categorised (correcting for age and gender) according to high fatigue and/or low muscle endurance, differences in inflammatory profile between fatigue categories were assessed by ANCOVA (corrected for PAS-2, %body fat and presence of inflammatory conditions). Overall, muscle endurance, fatigue and inflammatory markers were significantly interrelated. Higher levels of hsCRP (p < 0.001), IL-6 (p < 0.001), IL-10 (p = 0.035) and TNF-alpha (p = 0.028) were observed in participants presenting both low muscle endurance and high fatigue. IFN-γ was highest in those with high fatigue but normal muscle endurance (p = 0.015). Middle-aged participants with higher fatigue in combination with low muscle endurance show higher levels of inflammation, independently from physical activity, body fat and inflammatory pathology. The underlying mechanisms should be identified and future studies should also investigate whether these individuals show early signs of reduced physiological reserve capacity, which in later life come to full expression by means of frailty.
疲劳、肌肉耐力低下、肌肉无力和低度炎症与高龄虚弱密切相关。当自我感觉疲劳和肌肉耐力低下的迹象与中年期的低度炎症相互关联时,它们可能被用作体弱的早期标志物。本研究探讨了在中年是否可以观察到自我感觉疲劳、肌肉耐力和炎症之间的相互关系。研究人员对哥本哈根老龄化和中年生物库中的 965 名参与者(年龄为 52 ± 4 岁,男性 536 人,女性 426 人)进行了自我感觉疲劳(20 项多维疲劳量表)、肌肉耐力(握力)、炎症循环标志物(hsCRP、IL-6、IL-10、TNF-α 和 IFN-γ)、日常体力活动(PAS-2)、身体成分(通过生物阻抗评估体脂百分比)和自我健康状况评估。根据高疲劳度和/或低肌肉耐力对参与者进行分类(校正年龄和性别),并通过方差分析(校正 PAS-2、体脂百分比和炎症状况)评估疲劳类别之间炎症状况的差异。总体而言,肌肉耐力、疲劳和炎症指标之间存在显著的相互关联。在肌肉耐力低和疲劳度高的参与者中观察到较高水平的 hsCRP(p < 0.001)、IL-6(p < 0.001)、IL-10(p = 0.035)和 TNF-α(p = 0.028)。IFN-γ在高疲劳但肌肉耐力正常的参与者中含量最高(p = 0.015)。疲劳度较高且肌肉耐力较低的中年参与者的炎症水平较高,这与体力活动、体脂和炎症病理无关。应找出其潜在的机制,未来的研究还应调查这些人是否表现出生理储备能力降低的早期迹象,并在晚年通过虚弱的方式充分表现出来。
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引用次数: 0
Movement patterns during gait initiation in older adults with various stages of frailty: a biomechanical analysis 不同虚弱阶段的老年人步态启动时的运动模式:生物力学分析
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2024-01-13 DOI: 10.1186/s11556-024-00335-w
Jana Maria Hommen, João P. Batista, L. Cornelius Bollheimer, Frank Hildebrand, Thea Laurentius, Hannah Lena Siebers
Gait initiation is challenging for older individuals with poor physical function, particularly for those with frailty. Frailty is a geriatric syndrome associated with increased risk of illness, falls, and functional decline. This study examines whether spatial and temporal parameters of gait initiation differ between groups of older adults with different levels of frailty, and whether fear of falling, and balance ability are correlated with the height of lifting the food during gait initiation. Sixty-one individuals aged > 65 years, classified by Fried frailty phenotype, performed five self-paced gait initiation trials. Data was collected using a three-dimensional passive optical motion capture system, consisting of 10 cameras with the ability to perceive reflective markers, and two force plates. The total duration of gait initiation and the duration of its four sub-phases, the first step length, and the maximum foot clearance during the first step were derived, and compared statistically between groups. Additionally, an association analysis was conducted between foot clearance and fear of falling, and confidence in balance in older individuals. Frail individuals had significantly longer unloading durations, and total durations of gait initiation compared to non-frail older adults. Additionally, they had shorter first step lengths compared to non-frail older adults. Pre-frail older adults also showed shorter steps compared to the non-frail group. However, there were no significant differences between groups for the maximum foot clearance during the first step. Nevertheless, the maximum foot clearance of older individuals correlated significantly with their fear of falling and confidence in balance. Older adults with reduced physical function and signs of frailty mainly display longer duration of gait initiation and decreased first step length compared to non-frail older adults. The release phase is decreased as the double support phase is prolonged in frail patients. This information can guide the development of specialized exercise programs to improve mobility in this challenging motion between static and dynamic balance.
对于身体机能较差的老年人,尤其是体弱的老年人来说,步态启动是一项挑战。虚弱是一种老年综合症,与疾病、跌倒和功能衰退的风险增加有关。本研究探讨了步态起始的空间和时间参数在不同虚弱程度的老年人群体中是否存在差异,以及对跌倒的恐惧和平衡能力是否与步态起始时抬起食物的高度相关。根据弗里德虚弱表型分类的 61 名 65 岁以上的老年人进行了五次自步速步态启动试验。数据是通过三维被动光学运动捕捉系统收集的,该系统由 10 个能感知反射标记的摄像头和两个力板组成。得出了步态启动的总持续时间及其四个子阶段的持续时间、第一步长度和第一步期间脚的最大间隙,并对各组进行了统计比较。此外,还对老年人的足部间隙、跌倒恐惧和平衡信心进行了关联分析。与不虚弱的老年人相比,虚弱者的卸力持续时间和步态启动的总持续时间明显较长。此外,与非虚弱老年人相比,他们的第一步长度较短。与非虚弱组相比,虚弱前老年人的步长也较短。不过,在第一步的最大脚间隙方面,各组之间没有明显差异。不过,老年人的最大脚间隙与他们对跌倒的恐惧和对平衡的信心有很大关系。与不虚弱的老年人相比,身体功能减退和有虚弱迹象的老年人主要表现为步态启动持续时间更长,第一步长度减少。体弱患者的释放阶段会缩短,而双支撑阶段则会延长。这些信息可以为制定专门的锻炼计划提供指导,以改善这种介于静态和动态平衡之间的高难度运动的活动能力。
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引用次数: 0
The association of technology acceptance and physical activity on frailty in older adults during the COVID-19 pandemic period 在 COVID-19 大流行期间,技术接受度和体育活动对老年人虚弱程度的影响
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-12-19 DOI: 10.1186/s11556-023-00334-3
Rick Yiu Cho Kwan, Joanna Wing Yan Yeung, Janet Lok Chun Lee, Vivian W. Q. Lou
Physical activity was known to be the protective factor against frailty. Technology acceptance is associated with behavioural intention to technology usage. Technology has been effective in promoting healthy behaviour of physical activity. The purposes of this study were to examine the association between physical activity and technology acceptance with frailty and examine the moderation effect of technology acceptance on physical activity and frailty. We hypothesize that 1) physical activity and technology acceptance are associated with frailty, and 2) technology acceptance moderates the association of physical activity with frailty. This study employed a cross-sectional design and was conducted in the community settings of Hong Kong in 2021. Eligible participants were old people aged ≥60 and were community-dwelling. Key variables included physical activity measured by Rapid Assessment of Physical Activity (RAPA), social network measured by Lubben Social Network Scale-Six items (LSNS-6); depressive symptoms measured by Patient Health Questionnaire-Nine items (PHQ-9), technology acceptance measured by Senior Technology Acceptance Model-14 items (STAM-14) and frailty measured by Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight scale (FRAIL). Ordinal logistic regression was employed to test the hypotheses. The moderation effect was examined by introducing an interaction term formed by the multiplication of an independent variable (i.e., physical activity) and a moderating variable (i.e., technology acceptance). This study recruited 380 eligible participants with a mean age of 66.5 years. Technology acceptance (Beta = − 0.031, p < 0.001, Pseudo-R2 = 0.087) and physical activity (Beta = − 0.182, p = 0.003, Pseudo-R2 = 0.027) were associated with frailty in the unadjusted models. Technology acceptance (Beta = − 0.066, p < 0.001) and physical activity (Beta = − 1.192, p < 0.001) were also associated with frailty in the fully adjusted model (Pseudo-R2 = 0.352). Interaction term formed by the multiplication of technology acceptance and physical activity (Beta = 0.012, p = 0.001) was associated with frailty. Physical activity was significantly associated with frailty in the lower technology acceptance subgroup (Beta = − 0.313, p = 0.002) in the subgroup analysis. However, in the subgroup of higher technology acceptance, the association of physical activity (Beta = 0.104, p = 408) on frailty became positive but not significant. This study showed that physical activity and technology acceptance were associated with frailty, and technology acceptance moderated the association of physical activity with frailty. This study recommends engaging older adults in physical activity to combat frailty preferentially in those with a lower level of technology acceptance.
众所周知,体育活动是体弱的保护因素。技术接受度与使用技术的行为意向有关。科技能有效促进体育锻炼这一健康行为。本研究旨在探讨体育锻炼和科技接受度与体弱之间的关系,并探讨科技接受度对体育锻炼和体弱的调节作用。我们假设:1)体育锻炼和技术接受度与虚弱有关;2)技术接受度会调节体育锻炼与虚弱的关系。本研究采用横断面设计,于 2021 年在香港的社区环境中进行。研究对象为年龄≥60岁、居住在社区的老年人。主要变量包括体力活动量(RAPA)、社交网络(LSNS-6)、抑郁症状(PHQ-9)、科技接受度(STAM-14)以及虚弱程度(FRAIL)。为了检验假设,我们采用了顺序逻辑回归法。通过引入自变量(即体育锻炼)与调节变量(即技术接受度)相乘形成的交互项来检验调节效应。这项研究招募了 380 名符合条件的参与者,他们的平均年龄为 66.5 岁。在未调整模型中,技术接受度(Beta = - 0.031,p < 0.001,Pseudo-R2 = 0.087)和体力活动(Beta = - 0.182,p = 0.003,Pseudo-R2 = 0.027)与虚弱相关。在完全调整模型中,技术接受度(Beta = - 0.066,p < 0.001)和体育锻炼(Beta = - 1.192,p < 0.001)也与虚弱有关(Pseudo-R2 = 0.352)。技术接受度和体育锻炼的乘积形成的交互项(Beta = 0.012,p = 0.001)与虚弱有关。在亚组分析中,在技术接受度较低的亚组中,体力活动与虚弱明显相关(Beta = - 0.313,p = 0.002)。然而,在技术接受度较高的亚组中,体育锻炼(Beta = 0.104,p = 408)与虚弱的关系呈正相关,但不显著。本研究表明,体育锻炼和技术接受度与虚弱有关,而技术接受度调节了体育锻炼与虚弱的关系。本研究建议让老年人参加体育锻炼,以减轻技术接受度较低的老年人的虚弱状况。
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引用次数: 0
Patterns of physical activity among nursing home residents before and during the Covid 19 pandemic-a systematic observation. 2019冠状病毒病大流行之前和期间养老院居民身体活动模式的系统观察
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-12-06 DOI: 10.1186/s11556-023-00332-5
Lea-Sofie Hahn, Ansgar Thiel, Dorothée Trüb, Gerhard W Eschweiler, Andreas M Nieß, Gorden Sudeck, Annika Frahsa

Background: The Covid-19 outbreak in spring of 2020 posed an array of challenges for nursing homes, including promoting resident physical activity (PA). Given the diversity of factors affecting resident PA, we explored how activity patterns outside weekly-scheduled structured activities changed during the pandemic and what factors promoted or inhibited PA during the pandemic.

Methods: We conducted systematic direct observations over 823.5 h in eight nursing homes in Southern Germany in 2020 and 2021.

Results: In 2020, 84.7% of person observation units were classified as sedentary (average activity level: 1.14 MET). In 2021, the percentage increased to 91.6% of observed person units (average activity level: 1.08 MET) (t = 6.947; p = .000). According to tree classification, influencing factors of PA included mealtime and daytime in 2020 and 2021, as well as presence of men residents only in 2020 and guided low threshold activities in 2021.

Conclusions: Nursing homes constitute highly sedentary places-an issue exacerbated by access restrictions for external activity experts and significant others as well as behavioural restrictions for residents during the Covid-19 pandemic. Staff could not compensate due to existing time restraints and lack of training in PA promotion. Based on our findings, we recommend future studies to develop feasible and resource-low activities to be integrated into the daily routines of nursing homes.

背景:2020年春季的Covid-19疫情给养老院带来了一系列挑战,包括促进居民身体活动(PA)。考虑到影响居民PA的因素的多样性,我们探讨了在大流行期间,每周安排的结构化活动之外的活动模式如何变化,以及哪些因素在大流行期间促进或抑制了PA。方法:我们于2020年和2021年在德国南部的8家养老院进行了823.5小时的系统直接观察。结果:2020年,84.7%的人观察单位被归类为久坐(平均活动水平:1.14 MET)。到2021年,这一比例增加到91.6%(平均活动水平:1.08 MET) (t = 6.947;p = .000)。根据树分类,PA的影响因素包括2020年和2021年的用餐时间和白天,以及2020年仅男性居民存在和2021年引导低阈值活动。结论:疗养院是久坐不动的场所,在Covid-19大流行期间,外部活动专家和重要他人的进入限制以及居民的行为限制加剧了这一问题。由于现有的时间限制和缺乏PA晋升培训,工作人员无法补偿。基于我们的研究结果,我们建议未来的研究开发可行且资源低的活动,以整合到养老院的日常生活中。
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引用次数: 0
Is moderate resistance training adequate for older adults with sarcopenia? A systematic review and network meta-analysis of RCTs. 中度阻力训练对老年肌肉减少症患者足够吗?随机对照试验的系统回顾和网络荟萃分析。
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-11-29 DOI: 10.1186/s11556-023-00333-4
Yu Chang Chen, Wang-Chun Chen, Chia-Wei Liu, Wei-Yu Huang, ICheng Lu, Chi Wei Lin, Ru Yi Huang, Jung Sheng Chen, Chi Hsien Huang

Background: Resistance training (RT) and nutritional supplementation are recommended for the management of sarcopenia in older adults. However, optimal RT intensity for the treatment of sarcopenia has not been well investigated.

Methods: This network meta-analysis aims to determine the comparative effectiveness of interventions for sarcopenia, taking RT intensity into consideration. RT intensity was classified into light-to-moderate intensity RT(LMRT), moderate intensity RT(MRT), and moderate-to-vigorous intensity RT(MVRT) based on percentage of one repetition maximum (%1RM) and/or rating of perceived exertion.

Results: A total of 50 RCTs (N = 4,085) were included after screening 3,485 articles. The results confirmed that RT with or without nutrition was positively associated with improved measures of muscle strength and physical performance. Regarding RT intensity, LMRT only demonstrated positive effects on hand grip (aerobic training + LMRT + nutrition: mean difference [MD] = 2.88; 95% credential intervals [CrI] = 0.43,5.32). MRT provided benefits on improvement in the 30-s chair stand test (repetitions) (MRT: MD = 2.98, 95% CrI = 0.35,5.59), timed up and go test (MRT: MD = -1.74, 95% CrI: = -3.34,-0.56), hand grip (MRT: MD = 2.44; 95% CrI = 0.03,5.70), and leg press (MRT: MD = 8.36; 95% CrI = 1.87,13.4). MVRT also improved chair stand test repetitions (MVRT: MD = 5.64, 95% CrI = 0.14,11.4), gait speed (MVRT + nutrition: MD = 0.21, 95% CrI = 0.003,0.48), appendicular skeletal muscle index (MVRT + nutrition: MD = 0.25, 95% CrI = 0.01,0.5), and leg press (MVRT: MD = 14.7, 95% CrI: 5.96,22.4; MVRT + nutrition: MD = 17.8, 95% CrI: 7.55,28.6).

Conclusion: MVRT had greater benefits on muscle mass, lower extremity strength, and physical performance compared to MRT. Increasing RT intensity may be recommended for sarcopenic older adults.

背景:阻力训练(RT)和营养补充被推荐用于老年人肌肉减少症的治疗。然而,治疗肌肉减少症的最佳放疗强度尚未得到很好的研究。方法:本网络荟萃分析的目的是在考虑放疗强度的情况下,确定肌肉减少症干预措施的相对有效性。根据单次最大重复次数的百分比(%1RM)和/或感知运动的等级,将放射治疗强度分为轻至中等强度放射治疗(LMRT)、中等强度放射治疗(MRT)和中至剧烈放射治疗(MVRT)。结果:筛选3485篇文献后,共纳入50项rct (N = 4085)。结果证实,有或没有营养的RT与肌肉力量和身体表现的改善呈正相关。在训练强度方面,LMRT仅对握力有积极影响(有氧训练+ LMRT +营养:平均差值[MD] = 2.88;95%可信区间[CrI] = 0.43,5.32)。MRT在30秒椅立测试(重复)(MRT: MD = 2.98, 95% CrI = 0.35,5.59)、计时和行走测试(MRT: MD = -1.74, 95% CrI = -3.34,-0.56)、握把(MRT: MD = 2.44;95% CrI = 0.03, 5.70),腿压(捷运:MD = 8.36;95% CrI = 1.87,13.4)。MVRT还改善了椅立试验重复数(MVRT: MD = 5.64, 95% CrI = 0.14,11.4)、步速(MVRT +营养:MD = 0.21, 95% CrI = 0.003,0.48)、尾骨骼肌指数(MVRT +营养:MD = 0.25, 95% CrI = 0.01,0.5)和腿压(MVRT: MD = 14.7, 95% CrI: 5.96,22.4;MVRT +营养:MD = 17.8, 95% CrI: 7.55,28.6)。结论:与MRT相比,MVRT在肌肉质量、下肢力量和身体机能方面有更大的好处。对于肌肉减少的老年人,建议增加放疗强度。
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引用次数: 0
Agility training to integratively promote neuromuscular, cardiorespiratory and cognitive function in healthy older adults: a one-year randomized-controlled trial. 敏捷训练综合促进健康老年人的神经肌肉、心肺和认知功能:一项为期一年的随机对照试验
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-11-11 DOI: 10.1186/s11556-023-00331-6
Eric Lichtenstein, Steffen Held, Ludwig Rappelt, Jonas Zacher, Angi Eibl, Sebastian Ludyga, Oliver Faude, Lars Donath

Background: Exercise training recommendations for seniors include the targeted training of strength, balance, endurance and flexibility domains. Agility training (AT) is conceptualized as a multi-component and time-efficient training framework for older adults to improve physical, functional and cognitive health domains that are relevant for maintaining activities of daily living. The aim of this one-year trial was to comparatively evaluate the effects of agility training on physical and cognitive function.

Methods: Seventy-nine healthy older adults (AT: 61.5% female, 70.8 ± 4.8 years, 27.7 ± 4.2 kg/m2; CG: 60.5% female, 69.6 ± 4.7 years, 27.5 ± 4.4 kg/m2) took part in this one-year randomized controlled intervention and were either assigned to the agility training group (AT) with two weekly 60 min AT sessions or to the control group (CG), receiving no treatment. Participants were assessed pre, intermediate and post intervention for strength and power, balance, gait speed under multi-task conditions, aerobic capacity as well as cognitive performance. Linear mixed effects models were used to analyze the effect of treatment over time.

Results: Fifty-four participants (AG: 25, CG: 29) were analyzed, most drop-outs attributed to COVID-19 (17/30 dropouts). Adherence was good (75%) of 90 offered sessions. Notable effects in favor of AT were found for gait parameters in single (d = 0.355, Δ = 4.3%), dual (d = 0.375, Δ = 6.1%) and triple (d = 0.376, Δ = 6.4%) task conditions, counter movement jump performance (strength and power) (d = 0.203, Δ = 6.9%), static one leg balance (d = 0.256, Δ = 12.33%) and n-back reaction time (cognitive performance) (d = 0.204, Δ = 3.8%). No effects were found for the remaining outcomes (d < 0.175).

Conclusion: AT might serve as an integrative training approach for older adults particularly improving gait and lower limb power parameters. It seems suitable to improve a broad range of seniors' health domains and should replace isolated training of these domains. However, individual variation and progression of exercises should be considered when programming agility training providing adequate challenges throughout a long-term intervention for all participants.

Trial registration: DRKS, DRKS00017469 . Registered 19 June 2019-Retrospectively registered.

背景:老年人运动训练建议包括力量、平衡、耐力和柔韧性领域的针对性训练。敏捷训练(AT)是一种多组件和时间效率的训练框架,用于老年人改善与维持日常生活活动相关的身体,功能和认知健康领域。这项为期一年的试验的目的是比较评估敏捷训练对身体和认知功能的影响。方法:79例健康老年人(年龄:女性61.5%,70.8±4.8岁,27.7±4.2 kg/m2;CG: 60.5%女性,69.6±4.7岁,27.5±4.4 kg/m2)参加了为期一年的随机对照干预,并被分配到敏捷训练组(AT),每周进行两次60分钟的AT训练,或对照组(CG),不接受任何治疗。参与者在干预前、中期和干预后被评估力量和力量、平衡、多任务条件下的步态速度、有氧能力和认知表现。线性混合效应模型用于分析随时间推移的治疗效果。结果:54名参与者(年龄:25人,年龄:29人)进行了分析,大多数退出归因于COVID-19(17/30)。在90个疗程中,依从性良好(75%)。在单任务(d = 0.355, Δ = 4.3%)、双任务(d = 0.375, Δ = 6.1%)和三任务(d = 0.376, Δ = 6.4%)、反动作跳跃表现(力量和力量)(d = 0.203, Δ = 6.9%)、静态单腿平衡(d = 0.256, Δ = 12.33%)和n-back反应时间(认知表现)(d = 0.204, Δ = 3.8%)中,对AT有显著影响。结论:AT可以作为老年人的一种综合训练方法,特别是改善步态和下肢力量参数。这似乎适合改善广泛的老年人健康领域,并应取代这些领域的孤立培训。然而,在为所有参与者提供长期干预的足够挑战的敏捷性训练时,应该考虑个体的变化和练习的进展。试验注册号:DRKS, DRKS00017469。2019年6月19日注册-回顾性注册。
{"title":"Agility training to integratively promote neuromuscular, cardiorespiratory and cognitive function in healthy older adults: a one-year randomized-controlled trial.","authors":"Eric Lichtenstein, Steffen Held, Ludwig Rappelt, Jonas Zacher, Angi Eibl, Sebastian Ludyga, Oliver Faude, Lars Donath","doi":"10.1186/s11556-023-00331-6","DOIUrl":"https://doi.org/10.1186/s11556-023-00331-6","url":null,"abstract":"<p><strong>Background: </strong>Exercise training recommendations for seniors include the targeted training of strength, balance, endurance and flexibility domains. Agility training (AT) is conceptualized as a multi-component and time-efficient training framework for older adults to improve physical, functional and cognitive health domains that are relevant for maintaining activities of daily living. The aim of this one-year trial was to comparatively evaluate the effects of agility training on physical and cognitive function.</p><p><strong>Methods: </strong>Seventy-nine healthy older adults (AT: 61.5% female, 70.8 ± 4.8 years, 27.7 ± 4.2 kg/m<sup>2</sup>; CG: 60.5% female, 69.6 ± 4.7 years, 27.5 ± 4.4 kg/m<sup>2</sup>) took part in this one-year randomized controlled intervention and were either assigned to the agility training group (AT) with two weekly 60 min AT sessions or to the control group (CG), receiving no treatment. Participants were assessed pre, intermediate and post intervention for strength and power, balance, gait speed under multi-task conditions, aerobic capacity as well as cognitive performance. Linear mixed effects models were used to analyze the effect of treatment over time.</p><p><strong>Results: </strong>Fifty-four participants (AG: 25, CG: 29) were analyzed, most drop-outs attributed to COVID-19 (17/30 dropouts). Adherence was good (75%) of 90 offered sessions. Notable effects in favor of AT were found for gait parameters in single (d = 0.355, Δ = 4.3%), dual (d = 0.375, Δ = 6.1%) and triple (d = 0.376, Δ = 6.4%) task conditions, counter movement jump performance (strength and power) (d = 0.203, Δ = 6.9%), static one leg balance (d = 0.256, Δ = 12.33%) and n-back reaction time (cognitive performance) (d = 0.204, Δ = 3.8%). No effects were found for the remaining outcomes (d < 0.175).</p><p><strong>Conclusion: </strong>AT might serve as an integrative training approach for older adults particularly improving gait and lower limb power parameters. It seems suitable to improve a broad range of seniors' health domains and should replace isolated training of these domains. However, individual variation and progression of exercises should be considered when programming agility training providing adequate challenges throughout a long-term intervention for all participants.</p><p><strong>Trial registration: </strong>DRKS, DRKS00017469 . Registered 19 June 2019-Retrospectively registered.</p>","PeriodicalId":50477,"journal":{"name":"European Review of Aging and Physical Activity","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of caregiving grandparents' physical activity and sedentary behavior: a qualitative study using focus group discussions. 照顾祖父母的身体活动和久坐行为的决定因素:一项使用焦点小组讨论的定性研究。
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-10-26 DOI: 10.1186/s11556-023-00330-7
Marie Vermote, Tom Deliens, Benedicte Deforche, Eva D'Hondt

Background: Evidence on the factors influencing physical activity (PA) and sedentary behavior (SB) in middle-aged and older adults taking care of their grandchild(ren) is limited, even though this knowledge seems imperative when considering the unique relationship between grandparents and their grandchild(ren) as well as the rising popularity of intergenerational interventions targeting these energy-expenditure related behaviors. Therefore, this explorative qualitative study aimed to identify the determinants of PA and SB levels among Flemish caregiving grandparents in the presence of their grandchild(ren) aged between 0-5 years.

Methods: Six online focus group discussions were conducted via Microsoft Teams, all of which were audio- and videotaped with permission granted by the participating grandparents. In total, nine caregiving grandfathers and 28 caregiving grandmothers (overall mean age = 60.9 ± 4.1y) participated in this study. An inductive content analysis approach was used to derive subcategories, categories and themes from the verbatim transcribed data using NVivo R1.

Results: Caregiving grandparents' levels of PA and SB were both influenced by personal determinants (e.g., physical health, grandparental perceptions and responsibilities), interpersonal determinants (e.g., characteristics of the grandchild(ren), such as age-related physical/motor development and family interaction), and environmental determinants (e.g., weather and seasonal circumstances). PA levels of caregiving grandparents were further affected by additional personal determinants (e.g., age of the grandparent, planning and location) and interpersonal determinants (e.g., characteristics of the grandchild(ren), such as new experiences of the grandchild(ren)). Additionally, some personal determinants (e.g., perception of educational value) and interpersonal determinants (e.g., characteristics of the grandchild(ren), such as age-related cognitive development and health of the grandchild(ren)) were strictly mentioned to influence caregiving grandparents' SB.

Conclusions: Acknowledging the unique relationship between grandparents and their grandchild(ren), the current study identified specific factors determining grandparents' PA and SB levels during the provision of grandchild care. Besides, it turned out of importance to take the interplay between the different determinants into account. Especially, for those grandparents with older grandchild(ren), within the studied 0-5 years age range, more attention should be paid to grandchild characteristics as part of the interpersonal determinants when setting up interventions to improve levels of PA and SB in caregiving grandparents.

背景:关于影响中老年人照顾孙子(ren)的体育活动(PA)和久坐行为(SB)的因素的证据有限,尽管当考虑到祖父母和他们的孙子女之间的独特关系,以及针对这些能源支出相关行为的代际干预日益流行时,这些知识似乎是必不可少的。因此,这项探索性的定性研究旨在确定佛兰德照顾祖父母在0-5岁孙子孙女在场的情况下PA和SB水平的决定因素。方法:通过微软团队进行了六次在线焦点小组讨论,所有讨论都是在参与者祖父母允许的情况下录制的音频和视频。总共有9位照顾爷爷和28位照顾奶奶(总体平均年龄 = 60.9 ± 4.1y)参与了这项研究。使用NVivo R1,使用归纳内容分析方法从逐字转录的数据中推导出子类别、类别和主题。结果:照顾祖父母的PA和SB水平都受到个人决定因素(如身体健康、祖父母的感知和责任)、人际决定因素(例如孙子女的特征,如与年龄相关的身体/运动发育和家庭互动),以及环境决定因素(如天气和季节性环境)。照顾祖父母的PA水平进一步受到其他个人决定因素(如祖父母的年龄、计划和地点)和人际决定因素(例如孙子女的特征,如孙子女的新经历)的影响。此外,一些个人决定因素(如对教育价值的感知)和人际决定因素(例如孙子女的特征,如与年龄相关的认知发展和孙子女的健康)被严格提及,以影响照顾祖父母的SB。结论:承认祖父母和他们的孙子女之间的独特关系,目前的研究确定了在提供孙子孙女护理期间决定祖父母PA和SB水平的具体因素。此外,重要的是要考虑到不同决定因素之间的相互作用。特别是,对于那些有较大孙子女的祖父母,在研究的0-5岁年龄范围内,在制定干预措施以提高照顾祖父母的PA和SB水平时,应更多地关注孙子女特征,将其作为人际决定因素的一部分。
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引用次数: 0
Determining minimum number of valid days for accurate estimation of sedentary behaviour and awake-time movement behaviours using the ActivPAL3 in nursing home residents. 使用ActivPAL3在疗养院居民中确定准确估计久坐行为和清醒时运动行为的最小有效天数。
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-10-07 DOI: 10.1186/s11556-023-00329-0
Pau Farrés-Godayol, Miguel Ángel Ruiz-Díaz, Philippa Dall, Dawn A Skelton, Eduard Minobes-Molina, Javier Jerez-Roig, Maria Giné-Garriga

Introduction: Scarce evidence is available about the minimum number of valid days wearing the activPAL3 to obtain a precise estimate of sedentary behaviour (SB) and awake-time movement behaviours (ATMB) in nursing home (NH) residents. The study aimed to determine the minimum number of valid days required for accurately estimate SB and ATMB using the activPAL3 device in NH residents. It also investigated how the starting point of a day (the 24-h period) impacted reliability.

Methods: Participants wore an activPAL3 for 7 consecutive days. The data was classified in two-time blocks (00:00 Ante Meridiem (AM)-00:00 AM midnight vs 12:00 Post Meridiam (PM) -12:00 PM midday) and the sample was stratified into two groups according to their capacity to stand and walk, to examine if timing of sampling or physical functioning affected minimum wear time. SB, ATMB, sociodemographic, and health-related variables were collected. Sensitivity of the time-blocks were tested through the dispersion frequencies and differences between blocks through Kolmogorov-Smirnov test for normality; parametric variables through two-related means T-test and Wilcoxon test for non-parametric data. Reliability was assessed with the Cronbach's Alpha and the intra-class correlation coefficient (ICC), using a one-factor model estimating the reliability for each measurement day loading in the same latent factor.

Results: Ninety-five NH residents (81.1% women; age = 85.8 ± 7.2 years) were included. The midnight block had higher reliability, sensitivity and no statistically significant differences between days were found. At least three consecutive days of monitoring were necessary to achieve a reliability of ICC ≥ 0.8 for those NH residents able to stand and walk and six days for those unable.

Conclusions: NH residents who are able to stand and walk require a minimum of three consecutive days wearing the device, while those who are unable require at least six days due to their highly homogenous daily routines and sensitivity to PA events. Regardless of the activPAL3 recording start time, data processing should reference the midnight time block.

引言:关于佩戴activPAL3的最低有效天数,可以获得对疗养院(NH)居民久坐行为(SB)和清醒时运动行为(ATMB)的精确估计,这方面的证据很少。该研究旨在确定在NH居民中使用activPAL3设备准确估计SB和ATMB所需的最小有效天数。它还调查了一天的起点(24小时)如何影响可靠性。方法:参与者连续7天佩戴activPAL3。数据分为两个时间段(午夜前00:00(AM)-午夜00:00与午夜后12:00(PM)-中午12:00),并根据站立和行走能力将样本分为两组,以检查采样时间或身体功能是否影响最小磨损时间。收集SB、ATMB、社会人口学和健康相关变量。通过Kolmogorov-Smirnov正态性检验的色散频率和块之间的差异来测试时间块的灵敏度;通过两个相关的均值T检验和Wilcoxon检验对非参数数据进行参数变量检验。使用Cronbach’s Alpha和类内相关系数(ICC)评估可靠性,使用单因素模型估计同一潜在因素中每个测量日负荷的可靠性。结果:95名NH居民(81.1%为女性;年龄 = 85.8 ± 7.2年)。午夜阻断具有更高的可靠性和敏感性,并且没有发现天数之间的统计学显著差异。为了实现ICC的可靠性,至少需要连续三天的监测 ≥ 能够站立和行走的NH居民为0.8天,不能站立和行走者为6天。结论:能够站立和行走的NH居民需要至少连续三天佩戴该设备,而那些由于日常生活高度同质和对PA事件的敏感性而无法站立和行走者则需要至少六天。无论activPAL3记录的开始时间如何,数据处理都应参考午夜时间块。
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引用次数: 0
Change in physical activity and systolic blood pressure trajectories throughout mid-life and the development of dementia in older age: the HUNT study. 中年期间身体活动和收缩压轨迹的变化与老年痴呆症的发展:HUNT研究。
IF 6.3 1区 医学 Q1 Medicine Pub Date : 2023-10-02 DOI: 10.1186/s11556-023-00328-1
Maren Lerfald, Stian Lydersen, Ekaterina Zotcheva, Tom I L Nilsen, Rannveig S Eldholm, Nicolas Martinez-Velilla, Geir Selbæk, Linda Ernstsen

Background: There is lack of research on combinations of possible modifiable risk factors for dementia in a life-time perspective. Dementia has currently no cure, and therefore new knowledge of preventive factors is important. The purpose of this study is to investigate if changes in physical activity (PA) in combinations with systolic blood pressure (SBP) trajectories in mid to late life are related to development of dementia in older age.

Methods: This prospective cohort study uses data from four consecutive surveys of the HUNT Study, Norway. Dementia was assessed in the HUNT4 70 + sub-study (2017-19). Group-based trajectory modelling identified three SBP trajectories from HUNT1 (1984-86) to HUNT3 (2006-2008): low, middle, and high. Change in PA was categorized into four groups based on high or low PA level at HUNT1 and HUNT3 and were combined with the SBP trajectories resulting in 12 distinct categories. Logistic regression was used to estimate odds ratios (ORs) of dementia.

Results: A total of 8487 participants (55% women, mean age (SD) 44.8 (6.5) years at HUNT1) were included. At HUNT4 70 + , 15.2% had dementia. We observed an overall decrease in OR of dementia across the PA/SBP categories when ranked from low to high PA (OR, 0.96; 95% CI, 0.93 to 1.00, P = 0.04). Within PA groups, a low SBP trajectory was associated with lower OR for dementia, apart from those with decreasing PA. The strongest association was observed for people with stable high PA and low SBP trajectory (OR, 0.38; 95% confidence interval (CI), 0.13 to 1.10 and adjusted risk difference, -8.34 percentage points; 95% CI, -15.32 to -1.36).

Conclusion: Our findings illustrate the clinical importance of PA and SBP for dementia prevention and that favorable levels of both are associated with reduced occurrence of dementia.

背景:从生命周期的角度来看,缺乏对痴呆症可能的可改变风险因素组合的研究。痴呆症目前还没有治愈方法,因此对预防因素的新认识很重要。本研究的目的是调查中晚期身体活动(PA)与收缩压(SBP)轨迹的变化是否与老年痴呆的发展有关。方法:这项前瞻性队列研究使用了来自挪威HUNT研究的四项连续调查的数据。在HUNT470中评估了痴呆症 + 子研究(2017-19)。基于组的轨迹建模确定了从HUNT1(1984-86)到HUNT3(2006-2008)的三个SBP轨迹:低、中和高。PA的变化根据HUNT1和HUNT3的高或低PA水平分为四组,并与SBP轨迹相结合,产生12个不同的类别。Logistic回归用于估计痴呆的比值比(OR)。结果:共有8487名参与者(55%为女性,HUNT1时平均年龄(SD)44.8(6.5)岁)被纳入。HUNT4 70 + , 15.2%患有痴呆症。我们观察到,当PA从低到高时,PA/SBP类别的痴呆OR总体下降(OR,0.96;95%CI,0.93到1.00,P = 0.04)。在PA组中,除了PA降低的人外,低SBP轨迹与痴呆症的OR较低有关。观察到,具有稳定的高PA和低SBP轨道的人的相关性最强(OR,0.38;95%置信区间(CI),0.13至1.10,调整后的风险差,-8.34个百分点;95%CI,-15.32至-1.36)。结论:我们的研究结果说明了PA和SBP对预防痴呆的临床重要性,并且两者的良好水平与减少痴呆的发生有关。
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European Review of Aging and Physical Activity
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