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Multilevel Determinants of Long COVID and Potential for Telehealth Intervention. 长 COVID 的多层面决定因素和远程保健干预的潜力。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-08-21 eCollection Date: 2024-08-01 DOI: 10.18865/EthnDis-2024-2
Molly Jacobs, Charles Ellis, Irene Estores

Background: Post-coronavirus disease 2019 (COVID-19) syndrome, or long COVID, has a variety of symptoms, but little is known about the condition. This study evaluated the association between individual factors, social determinants of health, and the likelihood of long COVID by assessing internet usage as an indicator of viable access to telehealth.

Methods: Data from the 2022 National Health Interview Survey identified adults who (1) reported a previous COVID-19-positive test and/or diagnosis and (2) experienced long COVID. A 2-stage selection model predicted COVID-19 infection in the first stage and long COVID in the second stage. To test the potential use of telehealth, binary dependent variable regression evaluated internet usage among respondents with long COVID.

Results: About 40% (N=10,318) of respondents had tested positive/been diagnosed with COVID-19, but less than 20% of them (N=1797) had long COVID. Although older respondents were less likely to have COVID (odds ratio [OR]=0.48; 95% confidence interval [CI]=0.44, 0.53), they were more likely to experience long COVID (OR=1.63; CI=1.37, 1.93). Relative to White individuals, Black individuals were less likely to have COVID (OR=0.78; CI=0.69, 0.89) but significantly more likely (OR=1.21; CI=1.09, 1.64) to experience long COVID. Long COVID was also more likely among low-income earners (first income-to-poverty ratio quartile OR=1.40, CI=1.14, 1.72; second income-to-poverty ratio OR=1.37, CI=1.14, 1.64) and those without a college degree (OR=1.42; CI=1.01, 1.66). There were no statistically significant differences in internet access between racial, geographic, or income groups.

Conclusion: Long COVID is significantly more likely among Black individuals and low-income households than among their counterparts, but with few recourses available, telehealth service delivery could be a feasible intervention mechanism.

背景:2019年冠状病毒病(COVID-19)后综合征或长COVID有多种症状,但人们对这种疾病知之甚少。本研究通过评估互联网使用情况作为远程医疗可行途径的指标,评估了个人因素、健康的社会决定因素与长COVID可能性之间的关联:方法:2022 年全国健康访谈调查的数据确定了以下成年人:(1)曾报告 COVID-19 阳性检测和/或诊断;(2)经历过长时间 COVID。一个两阶段选择模型在第一阶段预测 COVID-19 感染,在第二阶段预测长 COVID。为了测试远程医疗的潜在使用情况,二元因变量回归评估了患有长期 COVID 的受访者的互联网使用情况:约 40% 的受访者(N=10,318)检测结果呈阳性/被确诊感染了 COVID-19,但其中只有不到 20% 的受访者(N=1797)感染了长 COVID。虽然年龄较大的受访者感染 COVID 的可能性较低(几率比 [OR]=0.48; 95% 置信区间 [CI]=0.44, 0.53),但他们更有可能感染长期 COVID(OR=1.63; CI=1.37, 1.93)。与白种人相比,黑种人发生 COVID 的可能性较低(OR=0.78;CI=0.69,0.89),但发生长时间 COVID 的可能性明显更高(OR=1.21;CI=1.09,1.64)。低收入者(第一收入与贫困比率四分位数 OR=1.40,CI=1.14,1.72;第二收入与贫困比率 OR=1.37,CI=1.14,1.64)和无大学学历者(OR=1.42;CI=1.01,1.66)也更有可能经历长时间 COVID。不同种族、地域或收入群体在互联网接入方面没有明显的统计学差异:黑人和低收入家庭中长期 COVID 的可能性明显高于同类人群,但由于可利用的资源很少,远程医疗服务可能是一种可行的干预机制。
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引用次数: 0
Associations between Structural Racism, Environmental Burden, and Cancer Rates: An Ecological Study of US Counties. 结构性种族主义、环境负担和癌症发病率之间的关联:美国各县生态研究》。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-08-21 eCollection Date: 2024-08-01 DOI: 10.18865/EthnDis-2023-68
Joelle N Robinson-Oghogho, Kassandra I Alcaraz, Roland J Thorpe

Objective: In this study, we examined associations between county-level measures of structural racism and county-level cancer incidence and mortality rates between race groups while accounting for factors associated with cancer rates and county-level measures of environmental burden.

Methods: To explore this relationship, we conducted multiple linear regression analyses. Data for these analyses came from an index of county-level structural racism and publicly available data on 2015 to 2019 age-adjusted cancer rates from the US Cancer Statistics Data Visualization Tool, 2019 County Health Rankings and Roadmaps, the Environmental Protection Agency's 2006 to 2010 Environmental Quality Index, and 2015 to 2019 estimates from the US Census American Community Survey.

Results: County-level structural racism was associated with higher county cancer incidence rates among Black (adjusted incidence rate: 17.4, 95% confidence interval [95% CI]: 9.3, 25.5) and Asian/Pacific Islander populations (adjusted incidence rate: 9.3, 95% CI: 1.8, 16.9) and higher mortality rates for American Indian/Alaskan Native (adjusted mortality rate [AMR]: 17.4, 95% CI: 4.2, 30.6), Black (AMR: 11.9, 95% CI: 8.9, 14.8), and Asian/Pacific Islander (AMR: 4.7, 95% CI: 1.3, 8.1) populations than White populations.

Conclusion: Our findings highlight the detrimental impact of structural racism on cancer outcomes among minoritized populations. Strategies aiming to mitigate cancer disparities must embed processes to recognize and address systems, policies, laws, and norms that create and reproduce patterns of discrimination.

目的:在本研究中,我们考察了县级结构性种族主义措施与不同种族群体的县级癌症发病率和死亡率之间的关联:在这项研究中,我们考察了县级结构性种族主义措施与县级不同种族群体癌症发病率和死亡率之间的关系,同时考虑了与癌症发病率相关的因素以及县级环境负担措施:为了探讨这种关系,我们进行了多元线性回归分析。这些分析的数据来自县级结构性种族主义指数,以及美国癌症统计数据可视化工具(US Cancer Statistics Data Visualization Tool)、2019 年县级健康排名和路线图(2019 County Health Rankings and Roadmaps)、环境保护署 2006 年至 2010 年环境质量指数(Environmental Quality Index)和美国人口普查美国社区调查(US Census American Community Survey)2015 年至 2019 年估计值中有关 2015 年至 2019 年年龄调整后癌症发病率的公开数据:县级结构性种族主义与黑人(调整后发病率:17.4,95% 置信区间 [95%CI]:9.3, 25.5)和亚太裔人口(调整后发病率:9.3,95% CI:1.8, 16.9)较高的县级癌症发病率以及美国人较高的死亡率有关。9),美国印第安人/阿拉斯加原住民(调整后死亡率 [AMR]:17.4,95% CI:4.2,30.6)、黑人(AMR:11.9,95% CI:8.9,14.8)和亚太岛民(AMR:4.7,95% CI:1.3,8.1)的死亡率高于白人:我们的研究结果凸显了结构性种族主义对少数民族癌症治疗效果的不利影响。旨在减少癌症差异的战略必须包含认识和解决造成和重现歧视模式的制度、政策、法律和规范的过程。
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引用次数: 0
Parkinson's Disease Inequities in Daily Cognitive Activities: An Intersectional Approach. 帕金森病患者在日常认知活动中的不平等:交叉方法。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.113
Paris B Adkins-Jackson, Nicole Taikeff, Josephine Akingbulu, Justina F Avila-Rieger, Caitlin A Corona-Long

Objective: Intersectionality approaches to examining differences in Parkinson's disease (PD) based on racialized group, gender identity, and socioeconomic status (SES) are not well covered in the literature. Additionally, the differences in daily cognitive activities for persons diagnosed with PD by racialized group, gender, and SES are undetermined. This study was conducted to explore the differences in PD daily cognitive activities for diverse racialized groups by gender and SES.

Methods: This study was a secondary analysis of the Michael J. Fox Foundation's Fox Insight online clinical dataset. Persons with PD were partitioned into 16 racialized by gender groups (Black women, Indigenous men, Latina/x women, Asian men, etc.) that were used in within-group comparisons of low-, middle-, and high-SES-a new variable comprising education and income.

Results: Intersectional analyses revealed most items differed between low-SES and high-SES except for items associated with Black and Indigenous men, for whom significant differential item functioning was found between mid-SES and high-SES.

Conclusions: These findings revealed that within-group differences exist and may be missed in research in which social factors are adjusted for instead of included in the model.

目的:文献中没有很好地涵盖基于种族群体、性别认同和社会经济地位(SES)的交叉性方法来研究帕金森病(PD)的差异。此外,不同种族、性别和社会经济地位的帕金森病患者在日常认知活动方面的差异也尚未确定。本研究旨在探讨不同种族群体在帕金森病日常认知活动方面的性别和社会经济地位差异:本研究是对迈克尔-J-福克斯基金会的福克斯洞察在线临床数据集进行的二次分析。将患有帕金森病的人按性别分为 16 个种族化群体(黑人女性、土著男性、拉丁裔/x 女性、亚裔男性等),用于低、中、高社会经济地位组内比较--社会经济地位是由教育程度和收入组成的新变量:交叉分析表明,除与黑人和土著男性相关的项目外,大多数项目在低社会经济地位和高社会经济地位之间存在差异,在中社会经济地位和高社会经济地位之间,黑人和土著男性的项目功能存在显著差异:这些研究结果表明,群体内差异是存在的,在研究中可能会忽略社会因素,而不是将其纳入模型。
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引用次数: 0
Supporting Underserved Communities for Health Care: US Immigrants' Experiences with Social Support. 支持医疗服务不足的社区:美国移民的社会支持经历。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.66
Katrina Grace Sadang, Henry K Onyeaka, Michelle Guo, Elizabeth Daskalakis, Emma D Wolfe, Emma P Keane, Stephanie Fagbemi, Richard E Leiter, Rubiahna Vaughn, Hermioni L Amonoo

Background: Social support is associated with improved clinical outcomes but is understudied among US immigrants. We examined two types of social support, perceived health provider support and community support, and characterized perceptions of social support among US immigrants compared with nonimmigrants.

Methods: We conducted cross-sectional data analysis on self-reported data from Health Information National Trends Survey 5, Cycle 2. Population-level estimates were obtained using jack-knife replicate weights.

Results: Immigrant status was not associated with perceived health care provider support or community support. However, compared with nonimmigrants, US immigrants were more likely to report rarely (adjusted odds ratio [aOR]=3.07) or never (aOR=3.18) having access to emotional support.

Conclusions: Further research that incorporates nuanced factors (eg, time since arrival) that may influence social support in diverse US immigrant groups is needed to determine the impact of social support on health outcomes in an underserved and often overlooked population.

背景:社会支持与临床结果的改善有关,但对美国移民的研究却不足。我们研究了两种类型的社会支持,即感知到的医疗服务提供者支持和社区支持,并对美国移民与非移民的社会支持感知进行了比较:我们对第五次全国健康信息趋势调查(Health Information National Trends Survey 5)第二周期的自我报告数据进行了横截面数据分析。结果:移民身份与非移民身份没有关系:结果:移民身份与感知到的医疗服务提供者支持或社区支持无关。然而,与非移民相比,美国移民更有可能很少(调整后的几率比[aOR]=3.07)或从未(aOR=3.18)获得情感支持:需要进一步开展研究,纳入可能影响美国不同移民群体社会支持的细微因素(如抵达美国的时间),以确定社会支持对这一服务不足且经常被忽视的人群的健康状况的影响。
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引用次数: 0
Increasing Emotional Distress and Use of Health Services among Hospitality Industry Workers During and After the COVID-19 Lockdown. 在 COVID-19 封锁期间和之后,酒店业工人的情绪困扰和使用医疗服务的情况不断增加。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.75
Pearl C Kim, Christopher Cochran, Billy Bai, Neeraj Bhandari, Bethany Khan, Estella Sky Keyoung, Jay J Shen

Objective: To examine the emotional distress situation among hospitality industry workers and their access to and use of health care including telehealth services during the COVID-19 pandemic.

Methods: A survey was administered on the Qualtrics platform both in English and Spanish from November 18, 2020, to November 30, 2020, through the Culinary Workers Union in Nevada. A total of 1182 union members participated in the survey, of whom 892 completed the survey. Descriptive and multivariable regression analyses were conducted.

Results: Among 892 respondents, 78% were people of color; 71% were laid off or furloughed during the COVID-related shutdown, but most had access to health care. Further, 78.8% experienced at least 2 or more signs of emotional distress during the pandemic. Females and unemployment status were positively associated with experiencing emotional distress. About 43.5% received care through telehealth, although most did not prefer telehealth (74.2%). Only 18.3% of non-telehealth users were interested in telehealth and 15.0% had never heard about telehealth.

Conclusions: Health insurance coverage is essential for access to health services regardless of employment status. Strengthening mental health services, including psychological counselling for hospitality workers, is needed in such public health emergency situations as the ongoing COVID-19 pandemic.

目的研究在 COVID-19 大流行期间酒店业工人的情绪困扰情况及其获得和使用医疗保健(包括远程医疗服务)的情况:2020 年 11 月 18 日至 2020 年 11 月 30 日,通过内华达州烹饪工人工会在 Qualtrics 平台上以英语和西班牙语进行了一项调查。共有 1182 名工会会员参与了调查,其中 892 人完成了调查。调查进行了描述性分析和多变量回归分析:在 892 名受访者中,78% 是有色人种;71% 在与 COVID 相关的停工期间被解雇或停工,但大多数人都能获得医疗保健。此外,78.8%的受访者在大流行期间至少经历过两次或两次以上的情绪困扰。女性和失业状况与情绪困扰呈正相关。约 43.5% 的人通过远程医疗接受了治疗,但大多数人并不喜欢远程医疗(74.2%)。只有 18.3% 的非远程保健用户对远程保健感兴趣,15.0% 的用户从未听说过远程保健:结论:无论就业状况如何,医疗保险对于获得医疗服务至关重要。在 COVID-19 大流行这样的公共卫生紧急情况下,需要加强心理健康服务,包括为酒店服务人员提供心理咨询。
{"title":"Increasing Emotional Distress and Use of Health Services among Hospitality Industry Workers During and After the COVID-19 Lockdown.","authors":"Pearl C Kim, Christopher Cochran, Billy Bai, Neeraj Bhandari, Bethany Khan, Estella Sky Keyoung, Jay J Shen","doi":"10.18865/ed.34.2.75","DOIUrl":"10.18865/ed.34.2.75","url":null,"abstract":"<p><strong>Objective: </strong>To examine the emotional distress situation among hospitality industry workers and their access to and use of health care including telehealth services during the COVID-19 pandemic.</p><p><strong>Methods: </strong>A survey was administered on the Qualtrics platform both in English and Spanish from November 18, 2020, to November 30, 2020, through the Culinary Workers Union in Nevada. A total of 1182 union members participated in the survey, of whom 892 completed the survey. Descriptive and multivariable regression analyses were conducted.</p><p><strong>Results: </strong>Among 892 respondents, 78% were people of color; 71% were laid off or furloughed during the COVID-related shutdown, but most had access to health care. Further, 78.8% experienced at least 2 or more signs of emotional distress during the pandemic. Females and unemployment status were positively associated with experiencing emotional distress. About 43.5% received care through telehealth, although most did not prefer telehealth (74.2%). Only 18.3% of non-telehealth users were interested in telehealth and 15.0% had never heard about telehealth.</p><p><strong>Conclusions: </strong>Health insurance coverage is essential for access to health services regardless of employment status. Strengthening mental health services, including psychological counselling for hospitality workers, is needed in such public health emergency situations as the ongoing COVID-19 pandemic.</p>","PeriodicalId":50495,"journal":{"name":"Ethnicity & Disease","volume":"34 2","pages":"75-83"},"PeriodicalIF":3.4,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Everyday Violence: Immigration Enforcement, COVID-19, and Depression among Undocumented Young Adults in California. 日常暴力:移民执法、COVID-19 和加州无证青年中的抑郁症。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.84
Ezinne Nwankwo, Hye Young Choi, Steve Li, May Sudhinaraset

Background: The immigration enforcement system has significant effects on the health of immigrants, their families, and society. Exposure to the immigration enforcement system is linked to adverse mental health outcomes, which may have been exacerbated by sustained immigration enforcement activities during the COVID-19 pandemic.

Objectives: This study was conducted to investigate the association between exposure to immigration enforcement and the mental health of undocumented young adults in California during the COVID-19 pandemic.

Methods: Data are from the COVID-19 BRAVE (Building Community Raising All Immigrant Voices for Health Equity) Study, a community-engaged cross-sectional survey of the impacts of the COVID-19 pandemic on undocumented immigrants in California. A total of 366 undocumented immigrants between 18 and 39 years of age completed the online survey, which was conducted between September 2020 and February 2021. Multivariable logistic regression models were fit to examine the association between immigration enforcement exposure and depression.

Results: Almost all participants (91.4%) disclosed exposure to the immigration enforcement system, with most reporting an average of 3.52 (SD=2.06) experiences. Multivariate analyses revealed that an increase in the immigration enforcement exposure score was significantly associated with higher odds of depression (adjusted odds ratio [aOR]=1.24; 95% confidence interval [CI]: 1.10, 1.40), and women were 92% more likely to report depression than were men (aOR=1.92; 95% CI: 1.12, 3.31). Those who reported deportation fears were significantly more likely to be depressed (aOR=1.24; 95% CI: 1.10, 1.40).

Conclusions: Researchers should consider the mental health implications of a punitive immigration enforcement system, and policymakers should examine the impacts of immigration policies on local communities.

背景:移民执法系统对移民、其家人和社会的健康有重大影响。接触移民执法系统与不良的心理健康结果有关,而在 COVID-19 大流行期间持续的移民执法活动可能加剧了这种不良后果:本研究旨在调查 COVID-19 大流行期间加利福尼亚州无证青年接触移民执法与心理健康之间的关系:数据来自 COVID-19 BRAVE(建设社区,提高所有移民的健康平等之声)研究,这是一项社区参与的横断面调查,调查 COVID-19 大流行对加州无证移民的影响。共有 366 名年龄在 18 岁至 39 岁之间的无证移民完成了在线调查,调查时间为 2020 年 9 月至 2021 年 2 月。我们建立了多变量逻辑回归模型,以研究移民执法与抑郁症之间的关联:几乎所有参与者(91.4%)都披露了接触移民执法系统的经历,其中大多数人平均报告了 3.52 次(SD=2.06)。多变量分析显示,移民执法风险得分的增加与抑郁症发生几率的增加有显著关联(调整后的几率比[aOR]=1.24;95% 置信区间[CI]:1.10, 1.40),女性报告抑郁症的几率比男性高 92%(aOR=1.92;95% 置信区间:1.12, 3.31)。报告担心被驱逐出境的人患抑郁症的可能性明显更高(aOR=1.24;95% CI:1.10,1.40):研究人员应考虑惩罚性移民执法系统对心理健康的影响,政策制定者应研究移民政策对当地社区的影响。
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引用次数: 0
Conducting Community-Based Research in An African Immigrant Population: Lessons Learned. 在非洲移民群体中开展基于社区的研究:经验教训。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.60
Clara M Gona, Kathryn Kieran, Jennifer Durning, Lisa-Marie O'Brien, Rosalia Gotora, Tricia Gordon, Philimon N Gona

Background: Although small, the African immigrant population is one of the fastest growing immigrant populations in the United States. Emerging research indicates a high prevalence of noncommunicable preventable chronic conditions in this population. Like other African Americans, African immigrants are mistrustful of the health care system, hampering efforts for prevention and intervention research.

Purpose: To describe our experiences conducting 2 studies in an African immigrant community, discuss the lessons learned, and provide advice to researchers interested in conducting research in similar populations.

Design: The 2 published studies for which we derive lessons learned for this paper were a cross-sectional study and a qualitative study using focus group interviews. Participants included Zimbabwean immigrants in the Eastern United States recruited at religious festivals and community events. The 2 studies enrolled a total of 135 participants.

Results: Of our recruitment goal of 120 in the first study, we enrolled only 98 despite numerous efforts. However, after strategically partnering with a community advisory board (CAB), in the second study, we met our recruitment goal within 4 months. With the CAB, we recruited a larger proportion of men (38% versus 24%). Without the CAB, 350 individuals agreed to participate, but only 98 (28%) returned the questionnaire, whereas with the CAB, 40 agreed to participate, and 37 (93%) successfully completed the study.

Conclusion: Conducting health-related research in immigrants requires strategic partnerships with the community to build strong relationships between the research team and the target community. By nurturing these relationships, research teams can effectively access this hard-to-reach population and achieve high participation.

背景:非洲移民人口虽少,却是美国增长最快的移民人口之一。新的研究表明,非传染性可预防慢性病在这一人群中的发病率很高。与其他非裔美国人一样,非洲移民也对医疗保健系统不信任,这阻碍了预防和干预研究工作的开展。目的:介绍我们在非洲移民社区开展两项研究的经验,讨论从中吸取的教训,并为有意在类似人群中开展研究的研究人员提供建议:设计:我们在这两项已发表的研究中总结了经验教训,这两项研究分别是一项横断面研究和一项采用焦点小组访谈的定性研究。参与者包括在宗教节日和社区活动中招募的美国东部津巴布韦移民。这两项研究共招募了 135 名参与者:在第一项研究中,我们的招募目标是 120 人,但经过多次努力,我们只招募到 98 人。然而,在第二项研究中,我们与社区咨询委员会(CAB)进行了战略合作,在 4 个月内就实现了招募目标。有了社区咨询委员会,我们招募到了更大比例的男性(38% 对 24%)。在没有社区咨询委员会的情况下,有 350 人同意参与研究,但只有 98 人(28%)返回了问卷,而在有社区咨询委员会的情况下,有 40 人同意参与研究,其中 37 人(93%)成功完成了研究:在移民中开展与健康有关的研究需要与社区建立战略伙伴关系,以便在研究团队与目标社区之间建立牢固的关系。通过培养这些关系,研究团队可以有效地接触到这一难以接触到的人群,并实现较高的参与率。
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引用次数: 0
Intracranial Volume Is Driven by Both Genetics and Early Life Exposures: The SOL-INCA-MRI Study. 颅内容积由遗传和生命早期暴露共同驱动:SOL-INCA-MRI 研究。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.103
Tamar Sofer, Einat Granot-Hershkovitz, Wassim Tarraf, Paola Filigrana, Carmen R Isasi, Shakira F Suglia, Robert Kaplan, Kent Taylor, Martha L Daviglus, Fernando D Testai, Donglin Zeng, Jianwen Cai, Myriam Fornage, Hector M González, Charles DeCarli

Intracranial volume (ICV) reflects maximal brain development and is associated with later-life cognitive abilities. We quantified ICV among first- and second-generation Hispanic and Latino adults from the Study of Latinos-Investigation of Cognitive Aging - MRI (SOL-INCA-MRI), estimated ICV heritability, and tested its associations with previously reported genetic variants, both individually and as a genetic risk score (GRS). We also estimated the association of ICV with early life environmental measures: nativity or age of immigration and parental education. The estimated heritability of ICV was 19% (95% CI, 0.1%-56%) in n=1781 unrelated SOL-INCA-MRI individuals. Four of 10 tested genetic variants were associated with ICV and an increase of 1 SD of the ICV-GRS was associated with an increase of 10.37 cm3 in the ICV (95% CI, 5.29-15.45). Compared to being born in the continental United States, immigrating to the United States at age 11 years or older was associated with 24 cm3 smaller ICV (95% CI, -39.97 to -8.06). Compared to both parents having less than high-school education, at least 1 parent completing high-school education was associated with 15.4 cm3 greater ICV (95% CI, 4.46-26.39). These data confirm the importance of early life health on brain development.

颅内容积(ICV)反映了大脑的最大发育程度,并与晚年的认知能力有关。我们对 "拉美裔认知老化调查-核磁共振成像研究"(SOL-INCA-MRI)中第一代和第二代拉美裔成年人的颅内容积进行了量化,估算了颅内容积的遗传率,并测试了颅内容积与之前报道的遗传变异的关联,包括单独遗传变异和遗传风险评分(GRS)。我们还估算了 ICV 与早期生活环境因素的关系:出生地或移民年龄以及父母的教育程度。在 1781 名无血缘关系的 SOL-INCA-MRI 患者中,ICV 的遗传率估计为 19%(95% CI,0.1%-56%)。在 10 个受测基因变异中,有 4 个与 ICV 相关,ICV-GRS 增加 1 SD 与 ICV 增加 10.37 立方厘米相关(95% CI,5.29-15.45)。与出生在美国大陆相比,11 岁或 11 岁以上移民到美国与 ICV 变小 24 立方厘米有关(95% CI,-39.97 至 -8.06)。与父母双方均未接受过高中教育相比,父母至少有一方完成高中教育与 ICV 增加 15.4 立方厘米有关(95% CI,4.46-26.39)。这些数据证实了生命早期健康对大脑发育的重要性。
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引用次数: 0
Clinic Staff Perceptions of Implementing a Sexual and Reproductive Health Entertainment-Education Program for Young Women of Color. 诊所工作人员对实施针对有色人种年轻女性的性与生殖健康娱乐教育计划的看法。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.93
Aaron Plant, Deborah Neffa-Creech, Emerald Snow, Jorge Montoya

Objective: Entertainment-education interventions remain underutilized in sexual and reproductive health (SRH) despite evidence that they can be effective and place a low burden on staff. This study explores perceived facilitators and barriers for implementing an entertainment-education video intervention for 18- to 19-year-old African American and Latina women in SRH clinics.

Design: Cross-sectional online survey (n=100) and telephone interviews (n=19) were completed May through August 2018.

Setting: SRH clinics were located across 32 US states and 1 Canadian province.

Participants: SRH clinic staff were diverse in type of clinic, role, and geography and were recruited using purposive sampling.

Methods: Bivariate analyses were used for quantitative data, and thematic analysis was used for qualitative data.

Main outcome measures: Intervention acceptability, perceived feasibility, and likely uptake were assessed using agreement statements (survey) and open-ended questions (interviews and survey).

Results: Interviewed clinic staff described the intervention as engaging, educational, and promising for improving client SRH knowledge and behaviors. Nearly all (95%) survey respondents said showing the video would be feasible. Most (56%) indicated likely uptake, which was significantly associated with perceived feasibility (P=.000), acceptability (P≤.001), and working at a public health clinic (P=.023). Implementation barriers included the video's potential relevance to only certain clients and the need for additional information or staff and/or management buy-in.

Conclusions: This is the first study to assess perceived implementation facilitators and barriers of an entertainment-education video intervention among SRH clinic staff. The intervention was well received, with certain barriers potentially alleviated by offering information about entertainment-education and multiple implementation methods. These findings can help improve dissemination efforts for video-based entertainment-education interventions in clinics serving young women of color.

目的:尽管有证据表明娱乐教育干预措施可能有效且对工作人员造成的负担较小,但在性与生殖健康(SRH)领域仍未得到充分利用。本研究探讨了在性与生殖健康诊所针对 18 至 19 岁的非裔美国人和拉丁裔女性实施娱乐教育视频干预的促进因素和障碍:横断面在线调查(n=100)和电话访谈(n=19)于 2018 年 5 月至 8 月完成:性健康和生殖健康诊所遍布美国 32 个州和加拿大 1 个省:性健康和生殖健康诊所的工作人员来自不同的诊所类型、角色和地域,采用目的性抽样的方式招募:方法:定量数据采用双变量分析,定性数据采用主题分析:主要结果测量:采用同意声明(调查)和开放式问题(访谈和调查)评估干预的可接受性、可感知的可行性和可能的采用率:结果:接受访谈的诊所工作人员认为该干预措施具有参与性和教育性,有望提高客户的性健康和生殖健康知识及行为。几乎所有(95%)调查对象都表示播放视频是可行的。大多数受访者(56%)表示可能会接受,这与他们认为的可行性(P=.000)、可接受性(P≤.001)和在公共卫生诊所工作(P=.023)有显著关联。实施障碍包括视频可能只与某些客户相关,以及需要更多信息或员工和/或管理层的支持:这是第一项评估性健康和生殖健康诊所工作人员对娱乐教育视频干预措施实施的促进因素和障碍的研究。该干预措施受到好评,通过提供娱乐教育信息和多种实施方法可能会缓解某些障碍。这些发现有助于在为有色人种年轻女性提供服务的诊所中更好地推广基于视频的娱乐教育干预措施。
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引用次数: 0
Community-Academic Partnerships for Health Research: An Iterative and Transparent Process of Patient Engagement Before the Research Begins. 社区与学术界合作开展健康研究:研究开始前患者参与的迭代和透明过程。
IF 3.4 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-02 eCollection Date: 2024-02-01 DOI: 10.18865/ed.34.2.53
T Joseph Mattingly, Claudia Rose Baquet, Franklin Lance, Michelle Medeiros, C Daniel Mullins

Background: The root causes of coronavirus disease 2019 (COVID-19) disparities include longstanding systemic racial bias in economic advancement and care delivery, discrimination, lack of access, and social determinants of health. To address these causes, research institutions and health care systems must shift their lens from one that focuses solely on changing behaviors among underserved and vulnerable populations to one that is inward facing.

Methods: We worked with a community advisory board and an African American church that has partnered on research for more than a decade to identify community norms, needs, and key resources needed for establishing community-academic partnerships for COVID-19 testing. Participants were purposefully sampled with equal representation from 3 groups: (1) church members and leaders, (2) academic or organization researchers with experience in community-engaged research, and (3) community members with experience participating in community-engaged research. Participants engaged in a hands-on exercise in the church basement as part of a town hall-style meeting.

Results: Active discussion led to the identification of business model components salient to COVID-19 testing in an underserved Baltimore community, predominantly made up of African Americans. Our discussion identified key partners, activities, resources, costs, value propositions, community relationships, community groups, communication channels, and outputs for community buy-in.

Conclusion: Developing the business case for mutual trustworthiness to be better prepared for future pandemics and public health crises may foster more sustainable community-academic partnerships. Using a Business Model Canvas, we delineate the major components, activities, and value propositions that are needed to achieve authentic community-academic partnerships to advance health equity.

背景:造成 2019 年冠状病毒疾病(COVID-19)差异的根本原因包括经济发展和医疗服务中长期存在的系统性种族偏见、歧视、缺乏机会以及健康的社会决定因素。为了解决这些问题,研究机构和医疗保健系统必须转变视角,从只关注改变服务不足和弱势群体的行为转变为面向内部:我们与一个社区咨询委员会和一个非裔美国人教会合作,该教会已在研究方面合作了十多年,旨在确定社区规范、需求以及为 COVID-19 检测建立社区-学术合作关系所需的关键资源。我们有目的地从以下 3 个群体中抽取了具有同等代表性的参与者:(1)教会成员和领导人;(2)具有社区参与研究经验的学术或组织研究人员;(3)具有参与社区参与研究经验的社区成员。作为市政厅式会议的一部分,与会者在教堂地下室进行了实践练习:通过积极讨论,我们确定了 COVID-19 在服务不足的巴尔的摩社区(主要由非洲裔美国人组成)进行测试所需的商业模式要素。我们在讨论中确定了关键合作伙伴、活动、资源、成本、价值主张、社区关系、社区团体、沟通渠道以及社区接受的产出:结论:开发相互信任的商业案例,为未来的流行病和公共卫生危机做好更充分的准备,可以促进社区与学术界建立更可持续的合作伙伴关系。我们使用 "商业模式画布"(Business Model Canvas)勾勒出实现真正的社区-学术合作以促进健康公平所需的主要组成部分、活动和价值主张。
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Ethnicity & Disease
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