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Brazilian Journal of Radiation Sciences最新文献

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An easy and direct protocol based on planar molecular images to quantify 131I using thyroid phantom 基于平面分子图像的简便直接方案,利用甲状腺模型量化 131I
Pub Date : 2023-12-29 DOI: 10.15392/2319-0612.2023.2325
Danny Giancarlo Apaza-Veliz, Vinicus Fernando dos Santos, D. L. Franze, Wilson Furlan Matos Alves, Eder Rezende Moraes
A planar nuclear medicine image can be used to estimate dosimetry during iodine therapy. To this end, radionuclide activity distribution should be quantified in the patient’s body in terms of a calibration coefficient. This coefficient allows the net counts to correlate with the image’s activity. This study aims propose a simple and easy calibration protocol to quantify 131I activity in thyroid phantom by molecular planar images. Were acquired 13 planar images of different phantoms: thyroid phantom of symmetrical lobes; thyroid phantom of asymmetrical lobes; the Jacszack cylinder phantom with a syringe surrounded by air and water, and finally a plastic bottle containing a syringe with radionuclide. We applied the 131I radionuclide in a General Electric gamma camera, model Discovery NM/CT 670 with a high energy general purpose parallel hole collimator above the phantoms positioned at camera bed. The calibration coefficient of the gamma camera and the standard deviation were determined for each phantom; the average calibration coefficient obtained was 0.062±0.006 MBq/cps. The results suggested that the phantoms applied as too the calibration coefficient obtained by them can provides reasonable value for the gamma camera calibration factor for iodine 131, therefore an accurate evaluation of the scattering media as the source detector distance could impose higher variability and uncertainties on results.
平面核医学图像可用于估算碘治疗过程中的剂量。为此,应根据校准系数对患者体内的放射性核素活度分布进行量化。该系数可以使净计数与图像的放射性活度相关联。本研究旨在提出一种简单易行的校准方案,通过分子平面图像量化甲状腺模型中的 131I 活性。我们采集了 13 幅不同模型的平面图像:对称叶甲状腺模型、不对称叶甲状腺模型、带有注射器的 Jacszack 圆柱模型(周围为空气和水)以及装有放射性核素注射器的塑料瓶。我们在通用电气公司的伽马相机(型号为 Discovery NM/CT 670)中使用了 131I 放射性核素,该相机带有一个高能量通用平行孔准直器,位于相机床上方的模型上。测定了每个模型的伽马相机校准系数和标准偏差;平均校准系数为 0.062±0.006 MBq/cps。结果表明,应用这些模型所得到的校准系数可以为碘 131 的伽马照相机校准系数提供合理的值,因此,准确评估散射介质作为源探测器的距离可能会给结果带来更大的变异性和不确定性。
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Brazilian Journal of Radiation Sciences
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