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Antibody deficiencies with normal IgG in adults with Non-cystic fibrosis bronchiectasis or recurrent pneumonia: Cross-sectional study. 成人非囊性纤维化支气管扩张或复发性肺炎的正常IgG抗体缺乏:横断面研究。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-05-30 eCollection Date: 2022-04-01 DOI: 10.25100/cm.v53i2.4832
Andres F Zea-Vera, Mario Alejandro Chacón, Beatriz Parra
Abstract Background: Inborn errors of immunity, mainly Predominantly Antibody deficiencies with normal IgG levels are unrecognized in adults with lung diseases such as bronchiectasis or recurrent pneumonia. Objective: To determine IgM, IgA, IgG2 subclass deficiencies, and Specific antibody deficiency (anti-pneumococcal polysaccharide antibodies) in adults with non-cystic fibrosis bronchiectasis or recurrent pneumonia. Methods: Cross-sectional study. Consecutive patients with non-cystic fibrosis bronchiectasis or recurrent pneumonia were recruited in Cali, Colombia. IgG, IgA, IgM, and IgE, IgG2subclass and IgG anti-pneumococcal serum levels were measured. Results: Among the 110 participants enrolled, Antibody deficiencies with normal serum IgG levels were found in 11(10%) cases. IgA deficiency (3 cases), IgM deficiency (2 cases) and IgG2 deficiency (2 cases) were the most frequent primary immunodeficiencies. In addition, IgG2+IgA deficiency, Ataxia-telangiectasia, Hyper-IgE syndrome and Specific Antibody Deficiency(anti-polysaccharides) were found in one case each. Conclusions: Predominantly antibody deficiencies with normal IgG levels are an important etiology of non-cystic fibrosis bronchiectasis and recurrent pneumonia in adults.
背景:先天性免疫缺陷,主要是IgG水平正常的抗体缺陷,在支气管扩张或复发性肺炎等肺部疾病的成人中未被发现。目的:检测成人非囊性纤维化支气管扩张或复发性肺炎患者的IgM、IgA、IgG2亚类缺陷和特异性抗体缺陷(抗肺炎球菌多糖抗体)。方法:横断面研究。在哥伦比亚卡利招募了非囊性纤维化支气管扩张或复发性肺炎的连续患者。测定抗肺炎球菌血清IgG、IgA、IgM、IgE、igg2亚类和IgG水平。结果:在纳入的110名参与者中,有11例(10%)患者血清IgG水平正常,但抗体缺乏。IgA缺乏症(3例)、IgM缺乏症(2例)和IgG2缺乏症(2例)是最常见的原发性免疫缺陷。IgG2+IgA缺乏症、共济失调性毛细血管扩张症、高ige综合征和特异性抗体缺乏(抗多糖)各1例。结论:IgG水平正常的抗体缺乏是成人非囊性纤维化、支气管扩张和复发性肺炎的重要病因。
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引用次数: 0
Prevalence and associated factors for asthma in adults in Quito: a cross-sectional study. 基多成人哮喘患病率及相关因素:一项横断面研究
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-05-30 eCollection Date: 2022-04-01 DOI: 10.25100/cm.v53i2.5086
Angelita Cabrera, César Picado, Sergio Barba, Oscar Fonseca, Eduardo Castro, Luis García-Marcos, Alejandro Rodríguez

Background: Although several epidemiological studies of asthma have been carried out in Ecuador in the last two decades, none of these has estimated the prevalence of asthma in adult populations.

Objective: To estimate the prevalence of asthma symptoms in adults in the city of Quito and to identify possible associated factors.

Methods: A cross-sectional study was conducted on subjects older than 18 years residing in the Metropolitan District of Quito. The Global Asthma Network (GAN) questionnaire was applied to collect information on asthma symptoms and sociodemographic and lifestyle data. Bivariate and multivariate analyses with logistic regression were used to identify asthma-related factors.

Results: 2,476 subjects answered the questionnaire (80.9% women, mean age 40 years). The prevalence of wheezing in the last 12 months, asthma ever, and asthma diagnosed by a doctor were 6.3%, 1.9% and 1.6%, respectively. The prevalence of rhinitis ever and eczema ever was 13.7% and 5.5%. The presence of mould at home (OR: 2.13; 95% CI: 1.48 -3.06; p <0.001), cat at home (OR: 1.06; 95% CI: 1.06 -2.13; p <0.022) and rhinitis at some time (OR: 3.65; 95% CI: 2.53 - 5.29; p <0.022) were associated with the presence of wheezing in the last 12 months.

Conclusions: Our study shows that, compared to other cities in Latin America, the prevalence of asthma in adults in Quito is relatively low. Along with the presence of rhinitis, factors related to housing quality are closely linked to the occurrence of asthma in adult populations.

背景:虽然在过去二十年中,厄瓜多尔开展了几项哮喘流行病学研究,但没有一项研究估计了成人哮喘的患病率。目的:估计基多市成人哮喘症状的患病率,并确定可能的相关因素。方法:对居住在基多大都市区的18岁以上的受试者进行横断面研究。应用全球哮喘网络(GAN)问卷收集有关哮喘症状和社会人口统计学和生活方式数据的信息。采用logistic回归的双变量和多变量分析来确定哮喘相关因素。结果:共2476人接受问卷调查,其中女性80.9%,平均年龄40岁。过去12个月哮喘患病率为6.3%,曾经哮喘患病率为1.9%,医生诊断哮喘患病率为1.6%。鼻炎和湿疹的患病率分别为13.7%和5.5%。家中存在霉菌(OR: 2.13;95% ci: 1.48 -3.06;结论:我们的研究表明,与拉丁美洲其他城市相比,基多成人哮喘患病率相对较低。随着鼻炎的存在,与住房质量相关的因素与成人哮喘的发生密切相关。
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引用次数: 0
Religiosity, physical and functional health in older people in Chile. 智利老年人的宗教信仰、身体和功能健康。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-04-10 eCollection Date: 2022-04-01 DOI: 10.25100/cm.v53i2.4846
M Beatriz Fernández Lorca

Objective: To establish the association between different dimensions of religiosity - organizational, non-organizational and intrinsic - and physical and functional health indicators in older people in Chile.

Methods: Data from the Fifth Survey on Quality of Life in Old Age 2019 were used. Descriptive and explanatory analyses were performed using logistic, linear and multinomial regression models, with dependent variables being self-perception of health, functional dependence, number of chronic diseases and perception of health compared with other people of the same age. As predictors, indicators of the three dimensions of religiosity (DUREL Scale) were included, controlling for the MOS-SS Social Support Scale, Apgar Family Functioning Scale, educational level, gender, age, and living with a partner.

Results: Almost a third of older Chileans attend religious services frequently, and half of them pray frequently. On a range of 1 to 5, the mean intrinsic religiosity is 3.94. 46% perceive their health to be good/very good and about half perceive their health as better than their peers. On 0 to 5, the mean number of chronic diseases is 1.69. 6% are classified as functionally dependent. The only significant relationship observed was between religious attendance and a lower probability of presenting functional dependency; on the other hand, praying increases such probabilities and a relationship between attendance and a better perception of health compared with other people of the same age.

Conclusion: Organisational religiosity is a psychosocial resource that is positively associated with the process of successful aging.

目的:确定智利老年人宗教信仰的不同方面——组织的、非组织的和内在的——与身体和功能健康指标之间的联系。方法:采用2019年第五次老年人生活质量调查数据。采用logistic、线性和多项回归模型进行描述性和解释性分析,因变量为自我健康感知、功能依赖、慢性疾病数量和与同龄人群比较的健康感知。以DUREL量表作为预测因子,控制MOS-SS社会支持量表、Apgar家庭功能量表、受教育程度、性别、年龄和同居关系。结果:近三分之一的智利老年人经常参加宗教仪式,其中一半经常祈祷。在1到5的范围内,平均内在宗教虔诚度为3.94。46%的人认为自己的健康状况良好/非常好,约一半的人认为自己的健康状况比同龄人好。从0到5,慢性疾病的平均数量是1.69。6%被归类为功能依赖。观察到的唯一显著关系是宗教出席与较低的功能依赖概率之间的关系;另一方面,与同龄的人相比,祈祷增加了这种可能性,也增加了出勤与更好的健康感知之间的关系。结论:组织宗教性是一种社会心理资源,与成功衰老过程呈正相关。
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引用次数: 0
The future of post-COVID-19 rehabilitation. 2019冠状病毒病后康复的未来。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-04-01 DOI: 10.25100/cm.v53i2.5261
Rodrigo Torres-Castro
From the overwhelming number of infected people (over 430 million people until February 2022) 1 , it was possible to predict that a significant percentage of them was going to develop sequelae, which would make it difficult for them to reintegrate to their jobs, families, and society, of courseNot all infected persons will present sequelae; however, the odds will be significantly higher for the ones affected by the most severe forms of the disease, such as those who suffered acute respiratory distress syndrome (ARDS), and particularly those with comorbidities, as well as older adults 2. In recent months, this topic has been so important that a new concept related to the persistence of symptoms for more than three months has appeared: persistent COVID, or “long COVID” 3. Without a doubt, this new condition allows us to think of persistent COVID as a chronic disease; therefore, rehabilitation takes on an even more preponderant role, not only because of the different systems involved but also because of the duration of the sequelae.
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引用次数: 0
Incidence and mortality by cancer in the Pasto municipality, Colombia. 2013-2017. 哥伦比亚帕斯托市癌症发病率和死亡率。2013-2017.
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.4952
Maria Clara Yépez Chamorro, Luisa Mercedes Bravo Goyes, Daniel Jurado Fajardo, Jaqueline Mena Huertas, Harold Mauricio Casas

Introduction: The information permanently produced by population cancer registries is the input used by decision makers of the local and national health systems in order for planning cancer prevention strategies and evaluating the impact of their interventions.

Objective: To determine the incidence and mortality from cancer in the municipality of Pasto Colombia, 2013-2017 period.

Methods: Descriptive observational study of cancer morbidity and mortality. The collection and processing of information was carried out following the recommendations of the IARC. Rates were calculated by sex, age, and tumor location.

Results: The overall incidence of cancer was 3,759 cases; 1,608 in men (AAR= 169.4 cases/100,000 men-year), and 2,151 cases in women (AAR= 176.6 cases/100,000 women-year). The most frequent tumors in men were: prostate (25.9%), stomach (16.5%) and lung (4.8%); and in women: breast (19.7%), thyroid (12.2%) and cervix (10.6%). There were 2,130 cancer deaths, 934 in men (AAR=97.8 deaths/100,000 men-year) and 1,196 deaths in women (AAR=95.1 deaths/100,000 women-year). The main causes of mortality in men were tumors of the stomach (24.8%), prostate (12.8%) and lung (7.5%). In women: breast (12.2%), stomach (11.6%) and cervix (10.0%).

Conclusion: The five-year follow-up of cancer burden indicators allows to make comparisons at both national and international levels, in order to provide the basis for planning and evaluating the implementation of public health policies; especially those related to the prevention and care of the most common causes of morbidity and mortality from cancer in Pasto-Colombia.

导言:地方和国家卫生系统的决策者在规划癌症预防战略和评估其干预措施的影响时,会使用人口癌症登记处永久生成的信息:确定 2013-2017 年哥伦比亚帕斯托市的癌症发病率和死亡率:癌症发病率和死亡率的描述性观察研究。信息的收集和处理遵循国际癌症研究机构的建议。按性别、年龄和肿瘤位置计算发病率:癌症总发病率为 3 759 例;男性为 1 608 例(AAR=169.4 例/100 000 男性年),女性为 2 151 例(AAR=176.6 例/100 000 女性年)。男性最常见的肿瘤是:前列腺癌(25.9%)、胃癌(16.5%)和肺癌(4.8%);女性最常见的肿瘤是:乳腺癌(19.7%)、甲状腺癌(12.2%)和宫颈癌(10.6%)。共有 2 130 例癌症死亡病例,其中男性 934 例(AAR=97.8 例/100 000 男性年),女性 1 196 例(AAR=95.1 例/100 000 女性年)。导致男性死亡的主要原因是胃部肿瘤(24.8%)、前列腺肿瘤(12.8%)和肺部肿瘤(7.5%)。女性:乳腺癌(12.2%)、胃癌(11.6%)和宫颈癌(10.0%):通过对癌症负担指标进行五年跟踪,可以在国家和国际层面进行比较,从而为规划和评估公共卫生政策的执行情况提供依据,特别是与帕斯托-哥伦比亚最常见的癌症发病和死亡原因的预防和护理有关的政策。
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引用次数: 0
The impact of the COVID-19 pandemic on the oncology services demand in a middle-income setting with universal health insurance. COVID-19大流行对拥有全民健康保险的中等收入环境中肿瘤服务需求的影响。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.5115
María Zuluaga Patiño, María Camila Luna Benitez, Natalie Jurado Sanabria, Beatriz Soto-Cala, Julio Cesar Solano Vega, Ricardo Antonio Sánchez Forero, Raúl Murillo

Aim: We analyze the impact of the COVID-19 pandemic on oncology service demand in a middle-income country with universal health coverage.

Methods: We collected data from January 1st-2017 to December 31th-2021 at a reference center in Bogotá-Colombia regarding first-time consultations of cross-cutting services (clinical oncology, hematology, palliative care, radiation oncology); specialized multidisciplinary units (breast, prostate, lung, stomach); inpatient and outpatient systemic therapy; radiotherapy; oncology surgery; and bone marrow transplant. A descriptive time series analysis was performed, estimating monthly percent change and endemic channels.

Results: Starting the confinement (April 2020), a general decrease in service demand was observed (R: -14.9% to -90.0%), with an additional but lower decrease in August 2020 coinciding with the first pandemic wave (R: -11.3% to -70.0%). Follow-up visits and ambulatory treatment showed no consistent reductions. New patients' consultations for cross-cutting services had a speedy recovery (1 month), but clinical oncology, specialized units, and in-hospital treatment resumed more slowly. Only breast and stomach cancer showed a sustained reduction in early-stage disease. Women and older patients had a more significant reductionin service demand. Conclusion: Despite no changes in service supply, the confinement induced a significant reduction in service demand. Variations by cancer type, service type, and population demographics deserve careful consideration for a suitable response to the emergency. The speedy recovery and the absence of a significant decrease during subsequent waves of the pandemic suggest patient resiliency and a lower impact than expected in middle-income settings in the presence of universal health insurance.

目的:我们分析了COVID-19大流行对实现全民健康覆盖的中等收入国家肿瘤服务需求的影响。方法:收集Bogotá-Colombia参考中心2017年1月1日至2021年12月31日跨领域服务(临床肿瘤学、血液学、姑息治疗、放射肿瘤学)首次会诊的数据;专科多学科单位(乳腺、前列腺、肺、胃);住院和门诊系统治疗;放射治疗;肿瘤手术;还有骨髓移植。进行描述性时间序列分析,估计每月百分比变化和流行渠道。结果:自隔离开始(2020年4月),观察到服务需求普遍下降(R: -14.9%至-90.0%),2020年8月与第一波大流行同时出现了进一步但较低的下降(R: -11.3%至-70.0%)。随访和门诊治疗没有一致的减少。新患者就诊交叉服务恢复迅速(1个月),但临床肿瘤学、专科和住院治疗恢复较慢。只有乳腺癌和胃癌的早期发病率持续下降。妇女和老年患者的服务需求下降更为明显。结论:在服务供给没有变化的情况下,限制导致了服务需求的显著减少。应仔细考虑癌症类型、服务类型和人口统计数据的差异,以便对紧急情况作出适当的反应。在随后的大流行浪潮中,迅速恢复和没有出现大幅下降表明患者的复原力,并且在存在全民健康保险的中等收入环境中,影响低于预期。
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引用次数: 0
Trends in long-term cancer survival in Cali, Colombia: 1998-2017. 1998-2017年哥伦比亚卡利地区癌症长期生存趋势
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.5082
Luis Eduardo Bravo, Luz Stella García, Paola Collazos, Jorge Holguín, Isabelle Soerjomataram, Adalberto Miranda-Filho

Background: Population-based cancer survival is an indicator of the effectiveness of cancer services that reflects the survival of all cancer patients in the population, regardless of socioeconomic status and disease characteristics.

Aim: Provision of an up-to-date survival estimate of patients recorded within Cali Population Cancer Registry (RPCC) in 1998-2017. As a second objective, results will be compared with those reported by the CONCORD study for cancers prioritized by the current Ten-Year Cancer Control Plan of Colombia, 2012-2021.

Methods: Adult cancer cases (aged 15 to 99 years) for nine cancer types diagnosed between 1998 and 2017, with follow-up to 2018, were obtained from the RPCC. The 5-year age-standardized net survival estimates (NS) were estimated using the Pohar-Perme. The results for the period 1995- 2014 were compared with those reported by the CONCORD study for the following locations: stomach (C16), breast (C50), cervix (C53), prostate (C61), and lung (C33-34).

Results: Five-year survival estimates for breast and prostate cancers improved ten percentage points through 2007 (70.8 to 81.1 for breast and 79.9 to 90.2 for prostate) and remained stable during 2008-2017. For cervical cancer, survival estimates has remained stable for the last two decades at 53%. For stomach cancer and lung cancer, five-year NS was lower than 25% over the study period. For colorectal cancer, survival estimates increased from 37.9% in 1998-2002 to 54.8% in 2013-2017. Compared to previous 5-year survival estimates of cases diagnosed in 2010-2014, the estimates in this study are significantly higher than those obtained by CONCORD. Survival estimates of patients diagnosed in 1995-2009 showed no difference to CONCORD study.

Conclusions: Periodic update of vital status and date of last contact reduces bias in survival estimates in population-based cancer registries with passive follow-up.

背景:基于人口的癌症生存率是癌症服务有效性的指标,反映了人口中所有癌症患者的生存率,而不考虑社会经济地位和疾病特征。目的:提供1998年至2017年卡利人群癌症登记处(RPCC)记录的患者的最新生存率估计。作为第二个目标,将结果与CONCORD研究报告的结果进行比较,该研究针对当前哥伦比亚癌症十年控制计划(2012-2021)中优先考虑的癌症。方法:1998年至2017年间诊断的九种癌症类型的成人癌症病例(15至99岁),以及2018年的随访,从RPCC获得。使用Pohar Perme对5年年龄标准化净生存率估计值(NS)进行估计。将1995-2014年期间的结果与CONCORD研究报告的以下位置的结果进行比较:胃(C16)、乳腺(C50)、宫颈(C53)、前列腺(C61),结果:截至2007年,乳腺癌和前列腺癌的五年生存率估计值提高了10个百分点(乳腺癌为70.8至81.1,前列腺癌为79.9至90.2),并在2008-2017年保持稳定。癌症宫颈癌的存活率在过去二十年中一直稳定在53%。对于癌症和癌症,在研究期间,五年NS低于25%。对于癌症,存活率估计从1998-2002年的37.9%增加到2013-2017年的54.8%。与之前对2010-2014年确诊病例的5年生存率估计相比,本研究中的估计值明显高于CONCORD获得的估计值。1995-2009年确诊患者的生存率估计值与CONCORD研究结果无差异。结论:定期更新生命状态和最后一次接触的日期减少了被动随访的癌症人群登记中生存率估计的偏差。
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引用次数: 0
Trends in cancer incidence and mortality in Manizales, Colombia, 2008-2017. 2008-2017年哥伦比亚马尼萨莱斯癌症发病率和死亡率趋势
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.4920
Nelson Arias-Ortiz, Juan David Rodríguez-Betancourt

Objective: To describe cancer incidence and mortality trends in Manizales, Colombia, between 2008-2017.

Methods: All incident cancer cases in Manizales collected by the Population-based Manizales Cancer Registry between January 1, 2008, and December 31, 2017, and all deaths caused by cancer in the same period, were included. The population at risk was obtained from the National Administrative Department of Statistics databases. Age-standardized incidence and mortality rates were calculated by sex and cancer site. Changes in trends were assessed using Joinpoint regression.

Results: There were 11,188 incident cases, 56.7% in women. There were 4,996 cancer deaths, 52.6% in women. Breast, prostate, stomach, thyroid, lung, and colon cancers accounted for 50% of all incident cases. During this period, the incidence in women decreased and equaled that of men due to a significant decrease in cervical, stomach, and lung cancers, among others; likewise, mortality in women decreased slightly due to the reduction in deaths from cervical, stomach, esophagus, and connective tissue cancers. In contrast, in men, overall incidence and mortality remained unchanged.

Conclusions: In Manizales, population aging has contributed to an increased burden of cancer. In terms of incidence and mortality, progress in the fight against this disease is still discrete. It is a priority to reinforce cancer control strategies with a differential approach by sex.

目的:描述2008-2017年哥伦比亚马尼萨莱斯地区癌症发病率和死亡率趋势。方法:纳入2008年1月1日至2017年12月31日马尼萨莱斯人口癌症登记处收集的马尼萨莱斯所有癌症病例,以及同期因癌症导致的所有死亡病例。高危人口数据来自国家统计行政部门的数据库。按性别和癌症部位计算年龄标准化发病率和死亡率。使用Joinpoint回归评估趋势的变化。结果:共11188例,其中女性占56.7%。4996人死于癌症,其中52.6%为女性。乳腺癌、前列腺癌、胃癌、甲状腺癌、肺癌和结肠癌占所有病例的50%。在此期间,由于宫颈癌、胃癌和肺癌等癌症的显著减少,妇女的发病率下降并与男性持平;同样,由于宫颈癌、胃癌、食道癌和结缔组织癌死亡人数减少,妇女死亡率略有下降。相比之下,在男性中,总体发病率和死亡率保持不变。结论:在马尼萨莱斯,人口老龄化导致癌症负担增加。就发病率和死亡率而言,防治这一疾病的进展仍然是离散的。按性别采取不同的方法加强癌症控制战略是一个优先事项。
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引用次数: 0
Age, period and cohort effects on mortality from cervical cancer in Colombia between 1985 and 2014. 年龄、时期和队列对1985年至2014年哥伦比亚宫颈癌死亡率的影响
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.4873
Lina Angélica Buitrago Reyes, Oscar Andrés Gamboa Garay, Jairo Alonso Hernández

Objective: To analyze the cervix cancer mortality in Colombia, based on age, period and cohort effects.

Methods: The mortality and population data were taken from the official databases of the National Administrative Department of Statistics, DANE. Five models were adjusted, the significance of the effects was obtained by comparing them through the likelihood ratio test.

Results: The age-adjusted mortality rate, in deaths was 15.09/100,000 woman, at 1985-1989 period, and 10.21 at 2010-2014 period. The annual percentage average change was -1.45% (95% CI: -1.57% to -1.34%). Age, period and cohort effects were found.

Conclusions: Demographic factors could explain the behavior of cervical cancer mortality in Colombia, as well as the establishment of public health measures in the last two decades.

目的:根据年龄、时期和队列效应分析哥伦比亚宫颈癌死亡率。方法:死亡率和人口数据来源于国家统计局官方数据库。对5个模型进行调整,通过似然比检验比较效果的显著性。结果:1985-1989年期间年龄调整死亡率为15.09/10万名妇女,2010-2014年期间为10.21 /10万名妇女。年平均变化百分比为-1.45% (95% CI: -1.57%至-1.34%)。发现了年龄、时期和队列效应。结论:人口因素可以解释过去二十年来哥伦比亚宫颈癌死亡率的行为,以及公共卫生措施的建立。
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引用次数: 0
Cancer incidence and mortality in Quito: information to monitor cancer control policies. 基多的癌症发病率和死亡率:监测癌症控制政策的信息。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-02-09 eCollection Date: 2022-01-01 DOI: 10.25100/cm.v53i1.4929
Patricia Cueva, Wilmer Tarupi, Henry Caballero

Introduction: Cancer represents a challenge for global public health, since it requires a comprehensive strategy for its control. In this context, the Population-Based Cancer Registries (PBCR) are key actors for the generation of public policies that guarantee their implementation.

Objective: This study analyses the trend in cancer incidence and mortality rates in the city of Quito during the period 1985-2017 and discusses them within the framework of the National Strategy against cancer proposed in 2017 for Ecuador.

Methods: Age-standardized incidence and mortality rates are established using data from the Quito PBCR. For trend analysis of selected locations, joinpoint regression and annual percentage change (APC) are used.

Results: Throughout the study period, there was a sustained increase in both incidence rates (APC male= 2.0, 95% CI: 1.7-2.4; APC female= 2.0%, 95% CI: 1.4-2.6), as in mortality rates (APC male= 2.0%, 95% CI: 1.8-2.3; APC female= 1.3%, 95% CI: 1.1-1.6). Cancer incidence and mortality rates of the breast, prostate, colon-rectum, thyroid, and lymphoma increased, while the incidence rates of cervical and stomach cancer initially decreased, then stagnation was observed.

Conclusion: The information presented by the PBCR of Quito serves as a reference for the prognosis of cancer in the country and as a baseline for its control. Actions are urgently required to strengthen cancer prevention and promotion strategies.

导言:癌症是对全球公共卫生的一项挑战,因为它需要一项全面的控制战略。在这种情况下,基于人口的癌症登记处(PBCR)是制定保证其实施的公共政策的关键角色。目的:本研究分析了基多市1985-2017年期间癌症发病率和死亡率的趋势,并在2017年为厄瓜多尔提出的国家癌症战略框架内进行了讨论。方法:使用基多PBCR的数据建立年龄标准化发病率和死亡率。对于所选地点的趋势分析,使用连接点回归和年百分比变化(APC)。结果:在整个研究期间,两种发病率均持续增加(男性APC = 2.0, 95% CI: 1.7-2.4;女性APC = 2.0%, 95% CI: 1.4-2.6),死亡率也是如此(男性APC = 2.0%, 95% CI: 1.8-2.3;APC女性= 1.3%,95% CI: 1.1-1.6)。乳腺癌、前列腺癌、结肠-直肠癌、甲状腺癌和淋巴瘤的发病率和死亡率增加,宫颈癌和胃癌的发病率先下降后停滞。结论:基多PBCR提供的信息可作为该国癌症预后的参考,并可作为其控制的基线。迫切需要采取行动,加强癌症预防和促进战略。
{"title":"Cancer incidence and mortality in Quito: information to monitor cancer control policies.","authors":"Patricia Cueva,&nbsp;Wilmer Tarupi,&nbsp;Henry Caballero","doi":"10.25100/cm.v53i1.4929","DOIUrl":"https://doi.org/10.25100/cm.v53i1.4929","url":null,"abstract":"<p><strong>Introduction: </strong>Cancer represents a challenge for global public health, since it requires a comprehensive strategy for its control. In this context, the Population-Based Cancer Registries (PBCR) are key actors for the generation of public policies that guarantee their implementation.</p><p><strong>Objective: </strong>This study analyses the trend in cancer incidence and mortality rates in the city of Quito during the period 1985-2017 and discusses them within the framework of the National Strategy against cancer proposed in 2017 for Ecuador.</p><p><strong>Methods: </strong>Age-standardized incidence and mortality rates are established using data from the Quito PBCR. For trend analysis of selected locations, joinpoint regression and annual percentage change (APC) are used.</p><p><strong>Results: </strong>Throughout the study period, there was a sustained increase in both incidence rates (APC male= 2.0, 95% CI: 1.7-2.4; APC female= 2.0%, 95% CI: 1.4-2.6), as in mortality rates (APC male= 2.0%, 95% CI: 1.8-2.3; APC female= 1.3%, 95% CI: 1.1-1.6). Cancer incidence and mortality rates of the breast, prostate, colon-rectum, thyroid, and lymphoma increased, while the incidence rates of cervical and stomach cancer initially decreased, then stagnation was observed.</p><p><strong>Conclusion: </strong>The information presented by the PBCR of Quito serves as a reference for the prognosis of cancer in the country and as a baseline for its control. Actions are urgently required to strengthen cancer prevention and promotion strategies.</p>","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fe/d7/1657-9534-cm-53-01-e2024929.PMC9651078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40720676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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Colombia Medica
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