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CT pattern of asymmetric contrast enhancing of the eye muscles in dogs with different position of the eyeballs 眼球位置不同的狗眼肌不对称对比度增强的 CT 模式
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-16-19
E. Kemel'man
The main aim of the study was to determine the cause of the asymmetric contrast enhancing of the eye muscles in dogs during CT. A group of 200 dogs with asymmetric contrast enhancing of the medial and lateral rectus muscles of the eye was formed. The research showed that regardless of the presence or absence of extracranial pathologies, provided there was no extensive invasion of those into the retrobulbar space, the asymmetric staining of eye muscles is associated with the position of eyeballs. With the eyeball turned laterally, the lateral rectus muscle acquires a more hyperdensive patter, with the eyeball turned medially, the medial rectus and oblique dorsal muscule acquires a more hyperdensive patter. There was not a single case when the difference in staining of the rectus muscles would not correspond to the position of eyeballs. No other reasons that could convincingly explain the pattern of asymmetric staining of eye muscles in dogs were found. This study is the first description of the pattern of asymmetric eye muscle contrast enhancing in dogs on CT.
这项研究的主要目的是确定在进行 CT 时狗眼部肌肉对比度不对称增强的原因。研究人员对 200 只眼睛内侧和外侧直肌对比度不对称增强的狗进行了分组。研究表明,无论是否存在颅外病变,只要没有广泛侵入球后间隙,眼肌的不对称染色都与眼球的位置有关。眼球转向外侧时,外侧直肌的染色更深;眼球转向内侧时,内侧直肌和斜背肌的染色更深。直肌染色的差异与眼球位置不一致的情况绝无仅有。没有发现其他可以令人信服地解释狗眼部肌肉不对称染色模式的原因。本研究首次描述了狗的眼肌在 CT 上的不对称对比增强模式。
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引用次数: 0
Alpha-2adrenoreceptor agonists. Dexmethedomidine α-2肾上腺素受体激动剂。右美托咪定
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-47-51
E. Kornyushenkov
Dexmethedomidine is a selective alpha2-adrenoreceptor agonist with a powerful sedative effect and analgesic properties. High selectivity of dexmedetomide (1620:1) makes it the optimal drug among all representatives of the alpha-2adrenoreceptor agonist class for use in relatively small animals. Dexmedetomidine is currently the most popular sedative used for premedication and sedation, as well as in multimodal analgesia in a constant-rate infusion mode in intensive care. In 2024, a domestic drug with the trade name «Dexody» of the pharmaceutical company «Apicenna» with the active substance dexmethedomidine was registered. The drug is a complete analogue of the original drug and is approved for use in veterinary medicine.
右美托咪定是一种选择性α2-肾上腺素受体激动剂,具有强大的镇静作用和镇痛特性。右美托咪定的高选择性(1620:1)使其成为α2-肾上腺素受体激动剂中最适合用于相对较小动物的药物。右美托咪定是目前最常用的镇静剂,可用于重症监护中的预处理和镇静,以及恒速输注模式下的多模式镇痛。2024 年,"Apicenna "制药公司注册了一种商品名为 "Dexody "的国产药物,其活性物质为右美托咪定。该药是原药的完全类似物,获准用于兽医。
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引用次数: 0
Radiography and radiographic measurements of the femur based on the CORA methodology. Part 1. Measurements of the femur in the frontal plane 基于 CORA 方法的股骨射线照相术和射线测量。第 1 部分。股骨正面测量
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-5-15
Igor' Samoshkin, Il'ya Vilkovyskiy
In the first part of the article based on the literature data, the principles and algorithm of performing femoral radiography in the fronta, plans are systematized, and literary data on the average physiological norms of femoral angles obtained in accordance with the CORA methodology are presented.
文章第一部分以文献资料为基础,系统阐述了在前庭、计划中进行股骨放射摄影的原则和算法,并介绍了根据 CORA 方法获得的股骨角度平均生理标准的文献数据。
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引用次数: 0
A clinical case of cardiopulmonary dirofilariasis in a cat 一例猫心肺双丝虫病临床病例
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-20-27
Svetlana Lutchenkova, Natal'ya Mochalova, Vladislava Illarionova
Heartworm disease is a vector-borne disease caused by the nematode Dirofilaria immitis, traditionally considered as a disease in dogs. However, it is also detected in cats, although the clinical sings and diagnostic approach to the patient are significantly different. This article discusses some features of the clinical sings, diagnosis and treatment using the example of a clinical case of heartworm disease in a cat.
心丝虫病是一种由线虫引起的病媒传染病,传统上被认为是狗的一种疾病。不过,猫也会感染这种疾病,只是临床症状和诊断方法明显不同。本文将以猫的心丝虫病临床病例为例,讨论临床症状、诊断和治疗的一些特点。
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引用次数: 0
Supplementation of feline hemoplasmosis treatment protocol with Gamavit and Phosprenyl increases the effectiveness of anemia correction: a retrospective analysis 在猫血吸虫病治疗方案中补充伽马维特和磷脂酰,可提高贫血纠正的效果:一项回顾性分析
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-41-46
Svetlana V. Savoyskaya
This study includes clinical data collected from 2016 to 2023. In total, hemoplasmosis was detected in 102 cats (63 females and 39 males) aged from 5 months to 8 years. Of these, 34 cats were diagnosed with a severe form of the disease, and 68 with a mild one. In cats with severe hemoplasmosis, in 45 % of cases, the disease was complicated by chronic renal failure. Also, 5 % of them were chronic carriers of toxoplasmas. Most of the animals were taken from shelters, or were homeless. One of the leading clinical signs of hemoplasmosis is anemia, which develops as a result of mass hemolysis of infected red blood cells. The aim of this work was to eliminate anemia and accelerate the normalization of hematopoiesis in cats with hemoplasmosis. For the treatment of 45 animals (control group), a standard therapy regimen was used, which included antibiotics and glucocorticoids, whereas for therapy regimen of remaining 57 cats (experimental group) Gamavit and Phosprenyl were added. Using this therapeutic scheme, early relief of anemia, stimulation of erythropoiesis, restoration of blood formula and normalization of liver function were noted as well as acceleration of clinical recovery of sick animals which occurred faster by 4…5 days.
本研究包括从 2016 年到 2023 年收集的临床数据。共有 102 只年龄在 5 个月到 8 岁之间的猫(63 只雌性,39 只雄性)被检测出患有血浆虫病。其中,34 只猫被诊断为重症,68 只为轻症。在患有严重血吸虫病的猫中,45%的病例并发慢性肾衰竭。此外,其中有 5% 的猫是弓形虫的慢性携带者。这些动物大多来自收容所或无家可归。血浆虫病的主要临床症状之一是贫血,这是受感染红细胞大量溶血的结果。这项工作的目的是消除患有血浆虫病的猫的贫血症状,并加速其造血功能恢复正常。对 45 只猫咪(对照组)的治疗采用了标准治疗方案,包括抗生素和糖皮质激素,而对其余 57 只猫咪(实验组)的治疗方案则添加了 Gamavit 和 Phosprenyl。采用这种治疗方案后,贫血症状得到了早期缓解,红细胞生成得到了刺激,血液配方得到了恢复,肝功能恢复正常,病猫的临床康复速度加快了 4...5 天。
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引用次数: 0
Efficacy of MASTIBLOCK Gel in the treatment of mastitis in cattle during lactation MASTIBLOCK 凝胶治疗牛哺乳期乳腺炎的疗效
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-35-40
Syergyey YEngashyev, Ekaterina Engasheva, Aleksey Savinkov, Konstantin Sadov, Denis Novikov
The purpose of the research was to study the effectiveness of a new medicinal product for veterinary use «MASTIBLOCK gel» in the treatment of mastitis in cows during lactation. 5 groups (10 animals each) of lactating cattle with various forms of mastitis were formed: group 1 – subclinical mastitis; group 2 – acute serous mastitis; group 3 – chronic serous mastitis; group 4 – acute catarrhal mastitis; group 5 – chronic catarrhal mastitis. For the 1st, 2nd and 4th groups, therapy was carried out for 7 days, for the 3rd and 5th – for 14 days. The drug was used externally for all animals, by applying a uniform layer of 50 g 2 times a day to the surface of the udder. At the beginning and end of treatment, blood was taken in each group for general blood test; milk was taken to assess bacterial contamination and assess the number of somatic cells. The clinical assessment of the condition of the animals was carried out daily. All the animals were kept in the same conditions. The diet of cows of all groups corresponded to the norms for this type and technological use of animals. The presence of pathology and the effectiveness of the drug were evaluated based on the results of a clinical examination of animals, the results of bacteriological analysis, a general blood test and a milk test for the number of somatic cells. As a result of the work carried out, based on the results of the study, it was found that the drug showed high therapeutic efficacy in various forms of mastitis caused by opportunistic microflora in lactating cows, and also helps to restore the qualitative characteristics of milk and reduce somatic cells in them.
研究的目的是研究兽用新药 "MASTIBLOCK 凝胶 "在治疗哺乳期奶牛乳腺炎方面的效果。将患有不同形式乳腺炎的泌乳牛分为 5 组(每组 10 头):第 1 组--亚临床乳腺炎;第 2 组--急性浆液性乳腺炎;第 3 组--慢性浆液性乳腺炎;第 4 组--急性卡他性乳腺炎;第 5 组--慢性卡他性乳腺炎。第 1 组、第 2 组和第 4 组的疗程为 7 天,第 3 组和第 5 组的疗程为 14 天。所有动物都是外用药,每天在乳房表面均匀涂抹 2 次,每次 50 克。在治疗开始和结束时,每组动物都要抽血进行一般血液检测;抽取牛奶以评估细菌污染和体细胞数量。每天对动物的状况进行临床评估。所有动物的饲养条件相同。各组奶牛的饮食均符合此类动物和技术使用的标准。根据动物临床检查结果、细菌学分析结果、一般血液检测结果和牛奶体细胞数检测结果,对是否存在病变和药物效果进行评估。研究结果表明,该药物对泌乳奶牛由机会性微生物菌群引起的各种形式的乳腺炎具有很高的疗效,还有助于恢复牛奶的质量特性并减少其中的体细胞。
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引用次数: 0
Evaluation of the effectiveness of a new drug Kurs Uspokoin tablets for the correction of age-related cognitive impairment in cats 评估新药 Kurs Uspokoin 片剂对矫正猫老年性认知障碍的效果
Pub Date : 2024-05-16 DOI: 10.32416/2500-4379-2024-2-28-34
Elena Elizarova, D. Beloglazov, S. Mukaseev, O. Zeynalov
The treatment by Kurs Uspokoin tablets in a minimum initial daily dose of 7 mg/kg for the first three days, with a further increase to 14 mg/kg, showed a positive effect in correcting the behavior of older cats with progressive simptoms of cognitive disfunction. During the treatment were registered a statistically and clinically significant decrease in idiopathic vocalization, restoration of sleep cycles and wakefulness, elimination of house-soiling behavior, disorientation, increased activity, and improvement of social behavior. During the treatment by Kurs Uspokoin tablets and after its discontinuation no adverse reactions were registered.
Kurs Uspokoin 片剂的最初剂量为每天 7 毫克/千克,连续服用三天,然后再增加到 14 毫克/千克,结果表明,这种药物对纠正患有渐进性认知功能障碍症状的老年猫的行为有积极作用。在治疗期间,特发性发声在统计和临床上都有显著减少,睡眠周期和清醒状态得到恢复,脏乱行为、迷失方向行为消失,活动增加,社交行为得到改善。在使用 Kurs Uspokoin 片剂治疗期间和停药后,没有发现任何不良反应。
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引用次数: 0
The pilot comparative clinical study of the anesthetic activity of a new domestic drug based on tiletamine-zolazepam «Vesotil®» and its original analogue «Zoletil® 100» 基于瓦他敏-唑拉西泮的国产新药 "Vesotil®"及其原始类似物 "Zoletil® 100 "的麻醉活性临床对比试验研究
Pub Date : 2024-02-28 DOI: 10.32416/2500-4379-2024-1-5-11
E. Kornyushenkov, Dar'ya Vdovina, Polina Anisimova, A. Shimshirt, Ekaterina Viktorova
This article presents the results of an original study on the therapeutic equivalence of the domestic drug «Vesotil®» based on a combination of drugs tiletamine-zolazepam, an analog drug «Zoletil® 100». «Vesotil®» was used as the main anesthetic for 28 animals (dogs and cats) undergoing surgery. «Vesotil®» has proven to be a safe and reliable drug, not inferior to the original one.
本文介绍了一项关于国产药物 "Vesotil®"治疗等效性的原创性研究结果,该药物基于瓦他敏-唑拉西泮的复方制剂,是一种类似药物 "Zoletil® 100"。"Vesotil®"被用作 28 种动物(狗和猫)手术的主要麻醉剂。事实证明,"Vesotil®"是一种安全可靠的药物,并不比原来的药物逊色。
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引用次数: 0
Evaluation of the effectiveness of a new drug Kurs Uspokoin tablets for the correction of age-related cognitive impairment in dogs 评估新药 Kurs Uspokoin 片剂矫正狗老年性认知障碍的效果
Pub Date : 2024-02-28 DOI: 10.32416/2500-4379-2024-1-33-39
Elena Elizarova, D. Beloglazov, O. Zeynalov, S. Mukaseev
The use of the drug Kurs Uspokoin tablets in a minimum initial daily dose of 7 mg/kg for the first three days, with a further increase in the minimum daily dose to 14 mg/kg, showed a positive effect in correcting the behavior of dogs older than 10 years with progressive signs of cognitive impairment.
Kurs Uspokoin 片剂在最初三天的最低日剂量为 7 毫克/千克,之后最低日剂量进一步增加到 14 毫克/千克。
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引用次数: 0
Study of the drug Nephrospas tolerability in cats 研究药物肾炎丸在猫体内的耐受性
Pub Date : 2024-02-28 DOI: 10.32416/2500-4379-2024-1-40-44
Roman Leonard, Syergyey YEngashyev, Aleksandr Komarov, Aleksandr Muromcev, A. Mironenko, Yuliya Aleksandrova
The article describes a tolerability study of the new drug Nephrospas, which contains telmisartan and excipients. The trial was conducted in cats with multiple daily administration at five times the therapeutic dose for 1 month (30 days). Two groups of animals were formed: experimental (10 cats) and control (7 cats). Animals of the experimental group were administered Nephrospas in a fivefold therapeutic dose of 0.5 ml/kg live weight of a cat orally during 30 days immediately after feeding. Animals of the control group were not administered the drug. Before the start of the experiment (day 0), on the 31st and 56th days of the experiment, weighing, thermometry, pulse and respiratory rates, blood pressure were determined, blood samples were taken for hematological studies (general clinical blood test, biochemical blood analysis), urine samples were taken for physical examination. chemical research. Based on the results of the conducted studies, it can be concluded that the drug Nephrospas is safe for cats when administered in excessive doses, as the use of the drug in a fivefold therapeutic dose does not adversely affect the general condition of animals, dynamics of body weight, blood pressure, does not change body temperature, morphological composition and biochemical parameters of blood, general clinical parameters of cat urine.
文章介绍了对新药Nephrospas的耐受性研究,该药含有替米沙坦和辅料。试验在猫科动物中进行,每天多次给药,剂量为治疗剂量的五倍,为期一个月(30 天)。试验分为两组:实验组(10 只)和对照组(7 只)。实验组动物在喂食后 30 天内立即口服治疗剂量五倍的肾炎宁,剂量为每公斤猫活重 0.5 毫升。对照组动物不给药。 在实验开始前(第 0 天)、实验第 31 天和第 56 天,测定体重、体温、脉搏和呼吸频率、血压,抽取血液样本进行血液学研究(一般临床血液测试、血液生化分析),抽取尿液样本进行体格检查和化学研究。根据所进行研究的结果,可以得出结论:超剂量使用肾炎灵对猫是安全的,因为以五倍治疗剂量使用该药物不会对动物的一般状况、体重动态、血压产生不利影响,也不会改变体温、血液的形态组成和生化参数、猫尿的一般临床参数。
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引用次数: 0
期刊
Russian veterinary journal
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