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A preliminary study of collaborative group intervention with recovered peer supporters for eating disorders: Analyses including comparisons between in‐person and online sessions 与饮食失调康复者同伴支持者合作进行小组干预的初步研究:分析包括现场和在线课程之间的比较
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.200
Yosuke Mochizuki, Tomoyo Isobe, Yuna Endo, Aina Iio, Kiyokazu Takebayashi, H. Yamasue
This study aimed to evaluate the impacts of a single‐session group intervention for individuals with an eating disorder that involved collaborations between peer supporters, who had recovered from an eating disorder, and psychological professionals. We also compared intervention effects between in‐person and online settings.Participants with an eating disorder were recruited through online platforms and public promotional materials. The inclusion criteria involved individuals who had current eating disorders and were willing to openly share their experiences during the session in which the Reflecting Team method was applied.The analysis included 103 participants (75 in‐person and 28 online). We found significant time‐based effects (F(1, 101) = 70.390, p < 0.001, ηG2 = 0.083), which indicated that participants experienced reductions in feelings of isolation, hopelessness associated with their eating disorder, and belief in the incurability of their disorder following the group interventions. No significant differences were observed between in‐person or remote sessions (F(1, 101) = 0.087, p = 0.768, ηG2 = 0.001).Our findings suggest that peer supporters serve as a source of hope for individuals with eating disorders, even within group settings. Furthermore, the similar outcomes across in‐person and online sessions show the promise of remote group sessions as a novel means of support for individuals with eating disorders, regardless of their geographical location. However, future randomized controlled trials of continuous group therapy sessions are essential to confirm their effectiveness.
本研究旨在评估针对饮食失调症患者的单节课小组干预措施的影响,该干预措施涉及饮食失调症康复者的同伴支持者与心理专业人士之间的合作。我们还比较了现场和网络环境下的干预效果。我们通过网络平台和公共宣传材料招募了饮食失调参与者。纳入标准包括目前患有饮食失调,并愿意在采用反思小组法的会议上公开分享自己的经历。我们发现了明显的时间效应(F(1, 101) = 70.390, p < 0.001, ηG2 = 0.083),这表明参与者在接受小组干预后,孤独感、与饮食失调相关的绝望感以及对饮食失调不可治愈的信念都有所减轻。我们的研究结果表明,同伴支持者是进食障碍患者的希望之源,即使是在小组环境中也是如此。此外,面对面和在线会议的相似结果表明,远程小组会议是为饮食失调症患者提供支持的一种新方法,无论他们身处何地。不过,未来对连续性小组治疗课程进行随机对照试验对确认其有效性至关重要。
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引用次数: 0
Correction to “Vortioxetine as a potential alternative for patients with escitalopram‐induced jitteriness/anxiety syndrome: A report of three cases” 更正 "伏替西汀作为艾司西酞普兰诱发的抖动/焦虑综合征患者的潜在替代药物:三个病例的报告"
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.211
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引用次数: 0
Effects of the tendency of developing neurodevelopmental disorder on subjective evaluation of distance learning among university students 神经发育障碍倾向对大学生远程学习主观评价的影响
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.197
Eiji Ikeda, Haruka Ikeda, Tetsuya Takahashi
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引用次数: 0
Impact of single versus multiple dose lithium on renal dysfunction in bipolar patients: A retrospective cohort study 单剂量与多剂量锂剂对双相情感障碍患者肾功能障碍的影响:回顾性队列研究
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.205
Hiroyuki Harada, Tadafumi Kato
Bipolar disorder significantly affects social functioning and maintenance treatment is crucial. Lithium is considered as a first‐line maintenance treatment in all treatment guidelines, but careful administration is necessary due to concerns about renal dysfunction caused by its use. Lithium can be administered in divided doses from two to three times a day or once a day. However, it is controversial which regimen, single or multiple dose, should be recommended in light of adverse effects. This study aims to clarify the difference in renal dysfunction due to the number of divided lithium doses using data from the electronic medical record in a retrospective cohort.We targeted 72 patients who were prescribed lithium carbonate for bipolar disorder in the Juntendo University Hospital electronic medical record from April 2021 to March 2023. There were 35 cases in the single‐dose group and 37 cases in the multiple‐dose group. The outcome was the change in creatinine and estimated glomerular filtration rate (eGFR) during the observation period. The effect of the regimen was evaluated using multiple regression analysis.There were no significant differences in the change in creatinine and eGFR between the single‐ and the multiple‐dose group, though renal function measured by creatinine and eGFR significantly worsened depending on the duration of treatment or aging.There was no significant difference in renal dysfunction between the single‐dose group and the multiple‐dose group; thus, considering the expected positive effect on adherence, a once‐daily regimen is recommended in maintenance lithium treatment.
躁郁症严重影响患者的社会功能,因此维持治疗至关重要。在所有治疗指南中,锂都被视为一线维持治疗药物,但由于担心使用锂会导致肾功能障碍,因此必须谨慎用药。锂可以分次服用,每天两到三次或每天一次。然而,考虑到不良反应,应推荐单剂量还是多剂量的治疗方案还存在争议。本研究旨在通过回顾性队列研究,利用电子病历中的数据,阐明分次给药的锂剂量导致的肾功能障碍的差异。我们的研究对象是顺天堂大学医院电子病历中,2021 年 4 月至 2023 年 3 月期间因双相情感障碍而被处方碳酸锂的 72 例患者。单剂量组 35 例,多剂量组 37 例。结果为观察期间肌酐和估计肾小球滤过率(eGFR)的变化。单剂量组和多剂量组的肌酐和 eGFR 变化无显著差异,但以肌酐和 eGFR 衡量的肾功能会因治疗时间长短或年龄增长而明显恶化。单剂量组和多剂量组的肾功能障碍无显著差异;因此,考虑到对依从性的预期积极影响,建议在锂维持治疗中采用每日一次的治疗方案。
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引用次数: 0
Hoarding medication and suicide attempts with 1180 tablets of mirtazapine overdose: A case report 囤积药物和服用1180片米氮平过量自杀未遂:病例报告
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.198
Yuki Kageyama, Ayaka Sukigara, Ayako Goto, Koki Inoue
Confirming a patient's consistent adherence to prescribed medication remains a persistent challenge for healthcare professionals. One reason for nonadherence is that patients accumulate their prescribed medicines with the intent of taking large quantities as a suicidal attempt. We present a case involving hoarding and overdosing on the highest quantity of mirtazapine ever reported.Our patient, a 44‐year‐old man suffering from depression, was admitted to our emergency department due to an overdose of 1180 mirtazapine tablets, equivalent to 17,700 mg. He exhibited a prolonged disturbance of consciousness, liver enzyme abnormalities, and serotonin syndrome. After 7 weeks in the intensive care unit, he was transferred to a psychiatric ward. Over time, his depressive symptoms improved, as did his suicidal ideation. On the 73rd day of his illness, he was discharged without any lasting effects, although he experienced retrograde amnesia.In this case, ensuring the patient's medication adherence is paramount. Implementing electronic prescription technologies may offer the potential to enhance healthcare by avoiding medication duplication, preventing stockpiling of duplicated medicine, and preventing overdosing.
对于医护人员来说,确认患者是否始终遵照处方用药仍然是一项长期的挑战。不遵医嘱的原因之一是患者囤积处方药,意图大量服药自杀。患者是一名 44 岁的男性抑郁症患者,因过量服用 1180 片米氮平(相当于 17,700 毫克)而被送入急诊科。他出现了长时间的意识障碍、肝酶异常和血清素综合征。在重症监护室住了 7 周后,他被转到了精神科病房。随着时间的推移,他的抑郁症状有所好转,自杀倾向也有所改善。在患病的第 73 天,他出院了,虽然出现了逆行性健忘症,但没有留下任何后遗症。采用电子处方技术可以避免重复用药、防止重复药品的囤积和防止用药过量,从而为改善医疗服务提供可能。
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引用次数: 0
Physical and psychosocial factors associated with fatigue in individuals with 22q11.2 deletion syndrome 与 22q11.2 缺失综合征患者疲劳相关的生理和心理社会因素
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.209
Yusuke Takahashi, Yutaka Sawai, Akito Uno, Miho Tanaka, Akiko Kanehara, Ryo Morishima, Yousuke Kumakura, Ichiro Sakamoto, Sho Yagishita, S. Jinde, Kiyoto Kasai
This study investigated fatigue in individuals with 22q11.2 deletion syndrome (22q11.2DS), identifying both physical and psychosocial factors.We conducted a cross‐sectional web‐based survey of 125 parents of individuals with 22q11.2DS. Significant factors of fatigue were identified using bivariate analysis and forward stepwise binary logistic regression.Overall, 34% (42 of 125) of the participants reported fatigue. Bivariate analysis identified 37 variables linked with fatigue, of which 11 were significant in multivariable analysis: older age (odds ratio [OR] = 1.28, 95% confidence interval [CI] [1.07, 1.53], P = 0.008), history of auditory hypersensitivity (OR = 36.4, 95% CI [4.08, 323.8], P = 0.001), delayed motor development (OR = 10.4, 95% CI [1.78, 61.0], P = 0.009), difficulty participating in events (OR = 33.5, 95% CI [1.1, 1068.2], P = 0.047), inability to join groups (OR = 47.9, 95% CI [4.8, 481.7], P = 0.001), concerns about marriage (OR = 17.0, 95% CI [2.6, 112.7], P = 0.003), inability to attend facilities (OR = 20.4, 95% CI [1.4, 308.0], P = 0.029), poor coordination when changing medical facilities (OR = < 0.010, 95% CI [0, 0.014], P = 0.002), lack of understanding about the individual's condition (OR = 0.010, 95% CI [0, 0.502], P = 0.021), and requirement of visiting multiple departments within the hospital (OR = 46.6, 95% CI [1.9, 1124.6], P = 0.018).Fatigue in 22q11.2DS is multifaceted, necessitating holistic fatigue management.
本研究调查了 22q11.2 缺失综合征(22q11.2DS)患者的疲劳情况,并确定了生理和社会心理因素。我们对 125 名 22q11.2DS 患者的父母进行了横断面网络调查。我们对 125 名 22q11.2DS 患者的父母进行了横断面网络调查,通过双变量分析和前向逐步二元逻辑回归确定了导致疲劳的重要因素。双变量分析确定了 37 个与疲劳有关的变量,其中 11 个在多变量分析中具有显著性:年龄较大(几率比 [OR] = 1.28,95% 置信区间 [CI] [1.07, 1.53],P = 0.008)、听觉过敏史(OR = 36.4,95% CI [4.08,323.8],P = 0.001)、运动发育迟缓(OR = 10.4,95% CI [1.78,61.0],P = 0.009)、参与活动困难(OR = 33.5,95% CI [1.1,1068.2],P = 0.047)、无法加入团体(OR = 47.9,95% CI [4.8,481.7],P = 0.001)、对婚姻的担忧(OR = 17.0,95% CI [2.6,112.7],P = 0.003)、无法到医疗机构就诊(OR = 20.4,95% CI [1.4,308.0],P = 0.029)、更换医疗机构时协调不佳(OR = < 0.010,95% CI [0,0.014],P = 0.22q11.2DS患者的疲劳是多方面的,需要全面的疲劳管理。
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引用次数: 0
The importance of methodological vigilance: Reevaluating suicide trends in Japan post‐2022 方法论警惕的重要性:重新评估 2022 年后日本的自杀趋势
Pub Date : 2024-06-01 DOI: 10.1002/pcn5.214
M. Koda, Nahoko Harada, Shuhei Nomura
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引用次数: 0
Psychedelic renaissance: A renewed focus on the clinical utility of hallucinogens 迷幻剂的复兴:重新关注致幻剂的临床用途
Pub Date : 2024-05-16 DOI: 10.1002/pcn5.196
Shunichiro Ikeda, Toshihiko Kinoshita
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引用次数: 0
Association of schizophrenia with fracture‐related femoral neck displacement: A cross‐sectional retrospective study 精神分裂症与骨折相关股骨颈移位的关系:横断面回顾性研究
Pub Date : 2024-05-06 DOI: 10.1002/pcn5.195
Yukiyo Inoue, Akihiro Tokushige, Takeshi Kinjyo, Shinichiro Ueda
Fracture‐related femoral neck displacement is more likely in patients with schizophrenia because of delayed diagnosis, as these patients frequently have less severe fracture‐associated subjective symptoms. This study aimed to investigate the association of schizophrenia with the risk of fracture‐related femoral neck displacement in hospitalized patients.We retrospectively analyzed the medical records of patients with femoral neck fractures treated between April 2013 and March 2018 at a single institution. Multivariate logistic regression was used to explore the relationship between schizophrenia and fracture‐related femoral neck displacement after adjusting for risk factors.We compared 30 and 194 patients with and without schizophrenia, respectively. The prevalence of fracture‐related displacement was 80.0% in patients with schizophrenia and 62.4% in the controls (p = 0.06). After adjusting for confounding variables, schizophrenia significantly correlated with fracture‐related femoral neck displacement (odds ratio: 4.74, 95% confidence interval: 1.09–20.60, p = 0.0378).Schizophrenia is associated with a higher risk of severe femoral neck fracture. To improve outcomes and alleviate the societal burden of femoral neck fractures, early radiographic assessment and surgical intervention for femoral fractures are essential for patients with schizophrenia, even in those without pain symptoms.
由于诊断延迟,精神分裂症患者更有可能发生骨折相关的股骨颈移位,因为这些患者经常有较轻的骨折相关主观症状。本研究旨在探讨精神分裂症与住院患者骨折相关股骨颈移位风险的关系。我们回顾性分析了一家机构在2013年4月至2018年3月期间收治的股骨颈骨折患者的病历。在调整风险因素后,我们采用多变量逻辑回归探讨了精神分裂症与骨折相关股骨颈移位之间的关系。精神分裂症患者骨折相关股骨颈移位发生率为80.0%,对照组为62.4%(P = 0.06)。在对混杂变量进行调整后,精神分裂症与骨折相关的股骨颈移位显著相关(几率比:4.74,95% 置信区间:1.09-20.60,p = 0.0378)。为了改善治疗效果并减轻股骨颈骨折对社会造成的负担,对精神分裂症患者,即使是没有疼痛症状的患者,也必须及早进行股骨颈骨折的影像学评估和手术治疗。
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引用次数: 0
Forensic analysis of suicide deaths: Comparing forensic information with public information and investigating factors contributing to psychiatric consultations 自杀死亡的法医分析:比较法医信息与公共信息,调查导致精神科就诊的因素
Pub Date : 2024-04-24 DOI: 10.1002/pcn5.194
Ryu Murakami, Atsushi Kamikubo, Daigo Morioka, Hisanaga Kuroki
This study aimed to examine the usefulness of forensic information on suicide deaths in Japan for epidemiological studies on suicide and determine the factors that lead people with suicidal ideation to seek psychiatric care prior to attempting suicide.We focused on forensic information of 514 suicide deaths that occurred in Osaka City in 2019. First, to examine whether the data used in this study can be generalized to these cases, we compared the information on suicide deaths officially published by Osaka City with that used in this study, utilizing Pearson's χ2 test. Next, the forensic data were analyzed using multivariate logistic regression analysis to confirm the relationship between demographic factors and the likelihood of having a history of psychiatric consultation before suicide.Both the official information and the data used in this study showed a higher number of males than females who died by suicide, with no significant differences in values between the data sets. Multivariate logistic regression analysis showed significant correlations. More females were associated with seeking a psychiatric consultation. However, those with regular jobs or students were more likely to avoid a psychiatric consultation.The findings of this study provide insights into the phenomenon of suicide deaths by using a forensic perspective. The results of this study suggest that psychiatric consultation may be effective in reducing deaths by suicide. Forensic data should be incorporated into the formulation of suicide‐prevention policies in Japan to conduct a more multifaceted analysis and improve suicide‐prevention measures.
本研究旨在探讨日本自杀死亡的法医信息对自杀流行病学研究的实用性,并确定导致有自杀意念的人在试图自杀前寻求精神治疗的因素。首先,为了检验本研究中使用的数据是否可以推广到这些案例中,我们将大阪市官方公布的自杀死亡信息与本研究中使用的信息进行了比较,使用了皮尔逊χ2检验。接下来,我们使用多元逻辑回归分析法对法医数据进行了分析,以确认人口统计学因素与自杀前有精神病咨询史的可能性之间的关系。多变量逻辑回归分析显示出了显著的相关性。更多女性与寻求精神科咨询有关。本研究的结果从法医的角度对自杀死亡现象进行了深入分析。研究结果表明,精神科咨询可能有效减少自杀死亡。日本在制定自杀预防政策时应纳入法医数据,以便进行更多方面的分析,改进自杀预防措施。
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引用次数: 0
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Psychiatry and Clinical Neurosciences Reports
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