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Development and Evaluation of a Prototype Mobile Application for Intravenous Drug Dose Calculation in Overweight and Obese Thai Children: Precision Dosing in Practice 开发和评估用于超重和肥胖泰国儿童静脉注射药物剂量计算的移动应用程序原型:实践中的精确配药
Pub Date : 2024-02-07 DOI: 10.1177/00185787241229141
Nuntapong Boonrit, Nansinee Klaidokchan, Apisit Niyomdecha, Janyaporn Noppamas, Krit Suknuntha, Pharsai Prasertsan, Supatcha Thaworncheep, Warit Ruanglertboon
Background: Medication dosing in overweight and obese children often involves complex weight-based calculations, leading to higher dosing errors, particularly with intravenous drugs. Currently, tools to aid in dosage calculations are lacking for these patients, especially in Thai population. Objective: This study aimed to develop a mobile application with the intent of utilizing it as a tool to enhance the efficiency and accuracy of dosing calculations required for obese and overweight Thai children. Methods: The performance of the application was assessed in 3 key aspects using a sample of 30 healthcare professionals. These key aspects included: 1) the accuracy of dosage calculations, assessed through pre- and posttests comparing manual calculations to app-based calculations using a 10-item questionnaire, 2) the time taken for calculations before and after app usage, 3) user satisfaction, which was measured through a questionnaire. Results: The integration of applications into the calculation demonstrated a significant improvement when compared to the manual calculation in both accuracy (6.10 vs 9.33 out of 10, P < .001) and efficiency (10.40 vs 8.53 minutes per 10 questions, P = .008). Also, the application elicited high levels of satisfaction among users, as reflected by an overall mean satisfaction score of 4.57 on a 5-point scale. Conclusion: The integration of this application to assist in dosage calculations for overweight and obese pediatric Thai patients has yielded favorable outcomes concerning accuracy, efficiency, and user satisfaction. Further development should be pursued within a larger cohort, with an emphasis on real-world implementation in clinical settings.
背景:超重和肥胖儿童的用药剂量往往涉及复杂的体重计算,从而导致较高的剂量误差,尤其是静脉注射药物。目前,对于这些患者,尤其是泰国人群,缺乏辅助剂量计算的工具。研究目的本研究旨在开发一款移动应用程序,将其作为一种工具来提高肥胖和超重泰国儿童所需剂量计算的效率和准确性。方法:对该应用程序的性能进行了评估:以 30 名医疗保健专业人员为样本,从 3 个关键方面对应用程序的性能进行了评估。这些关键方面包括1)剂量计算的准确性,通过使用 10 个项目的调查问卷对手动计算和基于应用程序的计算进行前后测试比较来评估;2)使用应用程序前后计算所需的时间;3)用户满意度,通过调查问卷进行测量。结果:与人工计算相比,将应用程序整合到计算中后,准确率(6.10 分对 9.33 分,P < .001)和效率(每 10 个问题 10.40 分钟对 8.53 分钟,P = .008)都有显著提高。此外,用户对该应用程序的满意度也很高,在 5 分制的评分标准中,总平均满意度为 4.57 分。结论整合该应用程序以协助超重和肥胖的泰国儿科患者进行剂量计算,在准确性、效率和用户满意度方面都取得了良好的效果。应在更大的群体中进行进一步开发,重点是在临床环境中的实际应用。
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引用次数: 0
Pharmaceutical Care in Mental Health: Pharmacists’ Barriers, Collaborations, Attitudes, and Perceptions 心理健康中的药物护理:药剂师的障碍、合作、态度和看法
Pub Date : 2024-02-07 DOI: 10.1177/00185787241229177
C. O. Iheanacho, Adepeju Oluwaseyi Tugbobo, U. Eze
Pharmaceutical care is an essential component of mental healthcare. The study assessed pharmacists’ collaborations, barriers, perceptions on therapeutic relationships and attitudes toward pharmaceutical care to persons with mental illness. A questionnaire-based descriptive cross-sectional survey was conducted among 175 pharmacists in a Nigerian state via purposive sampling. Average mean score of >3 (±SD) was considered positive attitude toward pharmaceutical care, and positive for respondents’ perception of pharmacists-patient relationship during consultations. Data were analyzed using SPSS version 25.0 for descriptive statistics. A total of 140 (80.0%) respondents participated in the study. Access to patients’ medical records 90 (64.3%) was the major barrier to the provision of pharmaceutical care to persons with mental illness. Almost half of the study participants 69 (49.3%) desired collaboration with only general practitioners and psychiatrists. Only 44 (31.4%) had full co-operation from their desired collaborators. Average score for respondents’ attitude toward provision of pharmaceutical care to the patients, and perception of pharmacist-patient relationship were 4.5 (±0.7) and 3.8 (±0.9) respectively. Study participants’ attitude toward pharmaceutical care, and perception on therapeutic relationship in persons with mental disorder were positive. Lack of access to patients’ records mostly hindered provision of pharmaceutical care, and full collaboration with other mental health experts was mostly lacking. Appropriate policies are required to improve these vital components of mental healthcare for desired outcomes.
药物治疗是精神医疗保健的重要组成部分。本研究评估了药剂师与精神病患者的合作、障碍、对治疗关系的看法以及对药物治疗的态度。通过有目的的抽样,对尼日利亚某州的 175 名药剂师进行了基于问卷的描述性横断面调查。平均得分大于 3 分(±SD)被认为是对药物治疗持积极态度,而受访者在咨询过程中对药剂师与患者关系的看法也是积极的。数据使用 SPSS 25.0 版进行描述性统计分析。共有 140 名(80.0%)受访者参与了研究。90名(64.3%)受访者认为,获取患者病历是为精神病患者提供药物治疗的主要障碍。近一半的研究参与者 69 人(49.3%)希望只与普通科医生和精神科医生合作。只有 44 人(31.4%)希望得到合作者的充分合作。受访者对为患者提供药物护理的态度和对药剂师与患者关系的看法的平均得分分别为 4.5 (±0.7) 和 3.8 (±0.9)。研究参与者对药物护理的态度以及对精神障碍患者治疗关系的看法都是积极的。由于无法获得患者的病历,药物护理的提供受到很大阻碍,而且大多缺乏与其他精神健康专家的充分合作。因此,需要制定适当的政策来改善精神医疗保健的这些重要组成部分,以达到预期的效果。
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引用次数: 0
Development and Evaluation of a Prototype Mobile Application for Intravenous Drug Dose Calculation in Overweight and Obese Thai Children: Precision Dosing in Practice 开发和评估用于超重和肥胖泰国儿童静脉注射药物剂量计算的移动应用程序原型:实践中的精确配药
Pub Date : 2024-02-07 DOI: 10.1177/00185787241229141
Nuntapong Boonrit, Nansinee Klaidokchan, Apisit Niyomdecha, Janyaporn Noppamas, Krit Suknuntha, Pharsai Prasertsan, Supatcha Thaworncheep, Warit Ruanglertboon
Background: Medication dosing in overweight and obese children often involves complex weight-based calculations, leading to higher dosing errors, particularly with intravenous drugs. Currently, tools to aid in dosage calculations are lacking for these patients, especially in Thai population. Objective: This study aimed to develop a mobile application with the intent of utilizing it as a tool to enhance the efficiency and accuracy of dosing calculations required for obese and overweight Thai children. Methods: The performance of the application was assessed in 3 key aspects using a sample of 30 healthcare professionals. These key aspects included: 1) the accuracy of dosage calculations, assessed through pre- and posttests comparing manual calculations to app-based calculations using a 10-item questionnaire, 2) the time taken for calculations before and after app usage, 3) user satisfaction, which was measured through a questionnaire. Results: The integration of applications into the calculation demonstrated a significant improvement when compared to the manual calculation in both accuracy (6.10 vs 9.33 out of 10, P < .001) and efficiency (10.40 vs 8.53 minutes per 10 questions, P = .008). Also, the application elicited high levels of satisfaction among users, as reflected by an overall mean satisfaction score of 4.57 on a 5-point scale. Conclusion: The integration of this application to assist in dosage calculations for overweight and obese pediatric Thai patients has yielded favorable outcomes concerning accuracy, efficiency, and user satisfaction. Further development should be pursued within a larger cohort, with an emphasis on real-world implementation in clinical settings.
背景:超重和肥胖儿童的用药剂量往往涉及复杂的体重计算,从而导致较高的剂量误差,尤其是静脉注射药物。目前,针对这些患者,尤其是泰国人群,缺乏辅助剂量计算的工具。研究目的本研究旨在开发一款移动应用程序,将其作为一种工具来提高肥胖和超重泰国儿童所需的剂量计算的效率和准确性。方法:对该应用程序的性能进行评估:以 30 名医疗保健专业人员为样本,从 3 个关键方面对应用程序的性能进行了评估。这些关键方面包括1)剂量计算的准确性,通过使用 10 个项目的调查问卷对手动计算和基于应用程序的计算进行前后测试比较来评估;2)使用应用程序前后计算所需的时间;3)用户满意度,通过调查问卷进行测量。结果:与人工计算相比,将应用程序整合到计算中后,准确率(6.10 分对 9.33 分,P < .001)和效率(每 10 个问题 10.40 分钟对 8.53 分钟,P = .008)都有显著提高。此外,用户对该应用程序的满意度也很高,在 5 分制的评分标准中,总平均满意度为 4.57 分。结论整合该应用程序以协助超重和肥胖的泰国儿科患者进行剂量计算,在准确性、效率和用户满意度方面都取得了良好的效果。应在更大的群体中进行进一步开发,重点是在临床环境中的实际应用。
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引用次数: 0
Prevalence of Obesity and its Effects in Patients With COVID-19: A Systematic Review and Meta-analysis COVID-19患者肥胖症的患病率及其影响:系统回顾与元分析
Pub Date : 2024-01-28 DOI: 10.1177/00185787231220318
S. M. Z. Qadar, Hina Naz, Sana Shamim, Faiza Hashim, Sohail Ahmed, Sandeep Kumar Mehraj
Background: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease worldwide. Obesity has been proven to increase the susceptibility of an individual to infections, but the relationship between obesity and COVID-19 is still unclear. This study aimed to conduct a systematic review and meta-analysis of the prevalence of obesity and its effects in patients with COVID-19. Methods: Web of Science, PubMed and Embase were searched for English language studies up to May 22, 2020. We used a random or fixed-effects model to calculate pooled prevalence rates and odds ratio (OR) with 95% confidence intervals (CI). Results: Twelve studies with a total of 14 364 patients met the inclusion criteria. The pooled prevalence of obesity in patients with COVID-19 was 32.0% (95% CI, 26%-38%, P < .001). The prevalence of obesity in ICU COVID-19 patients were 37.0% (95% CI, 29%-46%, P < .001). Comparing between obese and non-obese patients, the meta-analysis showed that obesity was an important risk factor associated with COVID-19 patients needed for ICU care (OR: 1.36, 95% CI 1.22-1.52, P < .001). Conclusion: Obesity was highly prevalent (32.0%) in patients with COVID-19, especially in ICU patients (37.0%), and was an important risk factor for COVID-19 patients needed for ICU care.
背景:冠状病毒病 2019(COVID-19)是一种新出现的全球性传染病。肥胖已被证实会增加个人对感染的易感性,但肥胖与 COVID-19 之间的关系仍不清楚。本研究旨在对 COVID-19 患者的肥胖患病率及其影响进行系统回顾和荟萃分析。研究方法检索了 Web of Science、PubMed 和 Embase 中截至 2020 年 5 月 22 日的英文研究。我们使用随机或固定效应模型来计算汇总的患病率和几率比(OR)以及 95% 的置信区间(CI)。研究结果有 12 项研究符合纳入标准,共纳入 14 364 名患者。COVID-19患者中肥胖症的汇总患病率为32.0%(95% CI,26%-38%,P < .001)。ICU COVID-19 患者的肥胖发生率为 37.0% (95% CI, 29%-46%, P < .001)。对比肥胖和非肥胖患者,荟萃分析表明肥胖是 COVID-19 患者需要接受 ICU 护理的重要风险因素(OR:1.36,95% CI 1.22-1.52,P < .001)。结论肥胖在 COVID-19 患者中的发病率很高(32.0%),尤其是在 ICU 患者中(37.0%),是 COVID-19 患者需要接受 ICU 治疗的重要风险因素。
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引用次数: 1
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Hospital Pharmacy
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