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Cerebrale ischemie als oorzaak van verminderd bewustzijn: het Percheron-infarct 导致意识障碍的脑缺血:佩尔切隆脑梗塞
Pub Date : 2024-07-23 DOI: 10.47671/tvg.80.24.052
C. De Bie, J. Tournoy, M. Van Wambeke, F. Couvreur, N. Fockaert, P. Matthyssen
Artery of Percheron infarction as an unusual cause of a reduced level of consciousness An acute onset of hemiparesis, aphasia or hemianopsia will promptly lead to the diagnosis of a stroke. However, a thalamic infarction does not always manifest with these classical symptoms due to its crucial role as a relay station between cortical brain structures, subcortical areas and the brainstem. The case of an 87-year-old woman with an altered state of consciousness due to bilateral thalamic ischemia as a result of an artery of Percheron infarction is reported. This case illustrates the clinical and diagnostic challenges in patients with an altered consciousness. The differential diagnosis is broad. One has to exclude a bilateral thalamic infarction since an early diagnosis of an ischemic stroke is crucial to initiate a proper treatment and thereby prevent morbidity and mortality.
丘脑动脉梗塞是导致意识减退的异常原因 急性发作的偏瘫、失语或半身不遂会很快被诊断为脑卒中。然而,丘脑梗死并不总是表现出这些典型症状,因为丘脑是大脑皮层结构、皮层下区域和脑干之间的重要中继站。本病例报告了一名 87 岁女性因佩尔切隆动脉梗塞导致双侧丘脑缺血而出现意识状态改变的病例。该病例说明了意识改变患者的临床和诊断难题。鉴别诊断的范围很广。必须排除双侧丘脑梗死,因为缺血性中风的早期诊断对于开始适当的治疗,从而防止发病率和死亡率至关重要。
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引用次数: 0
E-book: Antibiotica(resistentie) – Uitgave 2024 电子书:抗生素(抗药性)--2024 年的趋势
Pub Date : 2024-07-19 DOI: 10.47671/tvg.80.24.e006
J. Berwouts, C. Van haecht, R.-M. Ntahonganyira, J. Stokx, T. Pilate, V. Cossey, V. Saegeman, A. Schuermans, I. Verstreken, R. Reybrouck, L. Vander Elst, M. Verelst, J.-H. Keijzer, S. Mokrane, N. Dekker, M. Goossens, O. Vanderveken, A. De Sutter, R. Mehta, C. Ducène, A. Sousa, M. Boulad, P. Van Royen, L. Heyerick, A. Verbaeys, S. Delaet, A. Deconinck, J. Dewulf, B. De Muynck, M. Bouvry, M. Falter, K. Schoonheydt, L. Henckaerts, P. Bruynseels, J. Valk, N. Van Regenmortel, O. Maleux, A. Craeynest, J. Blok, C. Politis, D. Gorlé, K. Berquin, R. Snel, S. Kalantary, S. Ongena, A. Bral, V. Lenaerts, E. Bouckaert, T. Mulier, P. Reynders, B. Eneman, M. Lembrechts, P. Willems, S. Detienne, K. Paridaens, K. Mulkens, J. Dekoninck, Y.-M. Chong
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引用次数: 0
QTc-verlenging door antipsychoticagebruik binnen de kinder- en jeugdpsychiatrie: een systematische literatuurstudie 儿童与青少年精神病学中使用抗精神病药物导致的 QTc 延长:系统性文献综述
Pub Date : 2024-07-08 DOI: 10.47671/tvg.80.24.057
B. Dorpmans, L. Kiebooms, L. de Vries, M. Vrijens, M. Danckaerts
QTc prolongation associated with antipsychotic treatment in child and adolescent psychiatry: a systematic review Antipsychotics play a significant role in the treatment of psychiatric disorders. Monitoring of metabolic dysregulation and cardiac rhythm disturbances is essential. Given that the pharmacokinetic profile of children differs from that of adults, the literature cannot be extrapolated without consideration. Therefore, a systematic review on the risk of QTc prolongation in minors receiving antipsychotic treatment was conducted. The literature review was conducted within PubMed, Embase and Web of Science, focusing on randomized controlled trials (RCTs). Antipsychotics were selected based on the Belgian and Dutch formulary for the treatment of psychiatric disorders in minors. The study included 28 RCTs that examined the effect and safety of antipsychotic treatment in minors, including cardiac risks. The occurrence of clinically relevant QTc prolongation development is relatively rare. The comparison of the results was hindered by differences in the acquisition and correction of electrocardiograms (ECGs). It is advisable to identify risk factors through history-taking and blood sampling. Current research indicates that the risk of QTc prolongation and torsade de pointes in minors receiving antipsychotic treatment is relatively rare. However, vigilance is warranted in the presence of specific risk factors, in which case ECG monitoring is recommended.
儿童和青少年精神病学中与抗精神病药物治疗相关的 QTc 延长:系统综述 抗精神病药物在治疗精神疾病中发挥着重要作用。监测代谢失调和心律紊乱至关重要。鉴于儿童的药代动力学特征不同于成人,因此不能不考虑文献的推断。因此,我们对接受抗精神病药物治疗的未成年人出现 QTc 延长的风险进行了系统性回顾。文献综述在 PubMed、Embase 和 Web of Science 中进行,重点关注随机对照试验(RCT)。抗精神病药物是根据比利时和荷兰治疗未成年人精神障碍的处方集选定的。研究共纳入了 28 项随机对照试验,这些试验研究了抗精神病药物治疗对未成年人的效果和安全性,包括心脏风险。临床相关的 QTc 延长发生率相对较低。由于心电图(ECG)的采集和校正存在差异,因此无法对结果进行比较。建议通过询问病史和抽血来确定风险因素。目前的研究表明,接受抗精神病药物治疗的未成年人发生 QTc 延长和心搏过速的风险相对较小。不过,如果存在特定的风险因素,则应保持警惕,在这种情况下建议进行心电图监测。
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引用次数: 0
Transmediastinale migratie van een Kirschner-pin na fixatie van een proximale humerusfractuur: een casus 肱骨近端骨折固定后 Kirschner 销钉经腹腔移位:病例研究
Pub Date : 2024-07-02 DOI: 10.47671/tvg.80.24.049
C. Sneyers, S. Hens, G. Stassijns
Transmediastinal migration of a Kirschner pin after fixation of a proximal humeral fracture: a case report Fractures of the proximal humerus are common lesions in the elderly population. In some cases, they are surgically stabilized via a minimally invasive technique, namely percutaneous osteosynthesis with fixation pins. Intrathoracic migration of these pins or wire is a rare complication after percutaneous osteosynthesis of a proximal humeral fracture. In this article, the authors describe an extremely rare transmediastinal migration of a Kirschner pin from the humeral head. The purpose of this case report is to call for awareness and to open a debate in which appropriate prevention can be freely discussed. The consideration of a conservative management, the choice of alternative osteosynthesis techniques, the use of a sling bandage to restrict the shoulder movement, the use of fixation pins with a threaded tip, bending of the external free end of the pin and an appropriate time to remove the pin are possible recommendations from the literature. Furthermore, it is important to provide additional information and awareness to health care providers in rehabilitation centers, geriatricians and orthopedists concerning the possibility of such a life-threatening postoperative complication. Thus, specific policies for clinical and radiographic monitoring of the position of fixation pins should be developed in hospitals and rehabilitation centers with the aim of prevention, early detection and prompt action when this life-threatening complication is suspected.
肱骨近端骨折固定后 Kirschner 固定钉经腹腔移位:病例报告 肱骨近端骨折是老年人群中的常见病。在某些情况下,可通过微创技术(即使用固定钉的经皮骨合成术)进行手术稳定。肱骨近端骨折经皮骨结合术后,这些固定钉或钢丝的胸内移位是一种罕见的并发症。在本文中,作者描述了一例极为罕见的肱骨头Kirschner钉经胸内移位的病例。本病例报告的目的是呼吁人们提高警惕,并展开讨论,自由讨论适当的预防措施。文献中可能提出的建议包括:考虑保守治疗、选择其他骨合成技术、使用吊带绷带限制肩部活动、使用带螺纹的固定针、弯曲固定针的外部自由端以及拔出固定针的适当时间。此外,向康复中心的医护人员、老年病学家和矫形外科医生提供更多信息并提高他们对这种可能危及生命的术后并发症的认识也很重要。因此,医院和康复中心应制定对固定钉位置进行临床和影像学监测的具体政策,以预防、早期发现并在怀疑出现这种危及生命的并发症时立即采取行动。
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引用次数: 0
MCT bij ouderen 老年人的 MCT
Pub Date : 2024-07-01 DOI: 10.47671/tvg.80.24.010
S. Stoop, A. Nobels, G. Heylens
The number of elderly in our society is increasing. Psychiatric problems are common in this population. For adults aged 18 to 65, there already is psychiatric crisis home treatment for patients experiencing a psychiatric crisis at home. However, this did not yet exist in Belgium for adults over the age of 65. Since the 1st of November 2021, people over 65 who are experiencing a psychiatric crisis in the region of the Ghent-Eeklo-Flemish Ardennes Mental Health Care Network (PAKT) can rely on psychiatric crisis home treatment. For this reason, it was investigated whether this treatment is effective and cost-effective. There are currently no studies available on this subject. For this reason, different sub-aspects were considered. The effectiveness and cost-effectiveness of long-term psychiatric home treatment teams in elderly & adults and of psychiatric crisis home treatment teams (MCT) in adults older than 18 years were assessed. Finally, we looked for the characteristics of adults who were included for psychiatric crisis care at home and whether these are present in adults older than 65 years. Since there are no studies on MCT in the elderly, it is not possible to draw conclusions on the subject. However, a general trend is noted in the studies whereby the treatment always appears to be effective and often also cost-effective. However, further research is needed to confirm that this will also be the case for MCT for the elderly in Belgium.
我们社会中的老年人越来越多。精神问题在这一人群中很常见。对于 18 至 65 岁的成年人,已经有针对在家中遭遇精神危机的病人的精神危机家庭治疗。然而,在比利时,65 岁以上的成年人还没有这种服务。自 2021 年 11 月 1 日起,在根特-埃克洛-弗莱米什-阿登精神卫生保健网络(PAKT)区域内,65 岁以上的精神危机患者可以接受精神危机家庭治疗。为此,我们对这种治疗方法是否有效、是否具有成本效益进行了调查。目前还没有这方面的研究。为此,我们考虑了不同的子方面。我们评估了针对老年人和成年人的长期精神疾病家庭治疗小组以及针对 18 岁以上成年人的精神疾病危机家庭治疗小组(MCT)的有效性和成本效益。最后,我们调查了被纳入精神危机家庭护理的成年人的特征,以及这些特征是否存在于 65 岁以上的成年人中。由于没有关于老年人 MCT 的研究,因此无法就此得出结论。不过,从研究中可以发现一个总体趋势,即治疗似乎总是有效的,而且往往还具有成本效益。不过,还需要进一步研究,以确认比利时老年人的 MCT 治疗也是如此。
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引用次数: 0
Evidentie als onderbouwing voor ethisch verantwoorde, kwaliteitsvolle zorg 证据是道德和优质护理的基础
Pub Date : 2024-07-01 DOI: 10.47671/tvg.80.24.068
J. De Lepeleire
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引用次数: 0
E-book: De impact van voeding(ssupplementen) - Uitgave 2024 电子书:营养(补充剂)的影响 - 第 2024 期
Pub Date : 2024-05-17 DOI: 10.47671/tvg.80.24.e004
S. Vos, B. Van den Bergh, H. Roels, D. Martens, H. Kindermans, T.S. Nawrot, W. Gyselaers, M. Finoulst, P. Vankrunkelsven, E. De Waele, J. Gabriels, Y. Sluyts, H. De Cauwer, S. Dockx, M.-P. Assoignon, P. Deyaert, E. Colpaert, A. Pieters, A. Vonck, D. De Looze
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引用次数: 0
Atrio-oesofageale fistels na ablatie bij voorkamerfibrillatie: diagnose en aanpak voor de eerste lijn 心房颤动消融术后的贲门食管瘘:诊断和初级保健方法
Pub Date : 2024-05-16 DOI: 10.47671/tvg.80.24.032
G. Vos, K. Vrancken, H. Van Veer, P. Verbrugghe, P. Nafteux, F. Rega, L. Depypere
How to diagnose and manage atrio-esophageal fistulas occurring after atrial fibrillation ablation procedures? An atrio-esophageal fistula (AEF) is a rare complication occurring after an ablation procedure for atrial fibrillation, associated with a high mortality. The aim of this study is to provide a practical flowchart for first-line healthcare professionals on the diagnostics and management of these patients. A literature search was performed, resulting in the inclusion of 100 AEF cases after atrial fibrillation ablation procedures (85 reports). The documentation on these 100 patients was analyzed to compose the flowchart. All patients presented within 2 months after the ablation procedure (23 ± 11 days). Neurologic symptoms (75%), fever (73%) and both symptoms (57%) occurred in the majority. A CT scan of the chest was performed in 78% of the cases. In 30% of the patients, an AEF was observed. In other patients, the diagnosis was suspected based on air in the left cardiac circulation or the mediastinum. An esophagogastroscopy resulted in an infaust deterioration in 14/26 of the cases. In total, 41 patients received esophageal surgery (76% survival) versus 9 with only stenting (22% survival). In 27 patients, the diagnosis or treatment was not obtained in time. An AEF should be suspected in patients presenting with fever or neurological symptoms after a recent ablation procedure. CT scans of the chest and head can support the diagnosis. Once diagnosed, one should proceed to emergency surgery to prevent further complications. An esophagogastroscopy should be avoided. The authors hope to provide a practical management guide, allowing an earlier diagnosis, a faster treatment and thus an improved survival in these patients.
如何诊断和处理心房颤动消融术后出现的贲门食管瘘?贲门食管瘘(AEF)是心房颤动消融术后发生的一种罕见并发症,死亡率很高。本研究旨在为一线医护人员提供一份实用流程图,帮助他们诊断和处理这类患者。通过文献检索,共纳入了 100 例心房颤动消融术后 AEF 病例(85 份报告)。对这 100 例患者的文献资料进行分析后,绘制了流程图。所有患者均在消融术后 2 个月内(23 ± 11 天)发病。大多数患者都出现了神经系统症状(75%)、发热(73%)和两种症状(57%)。78%的病例进行了胸部 CT 扫描。在 30% 的患者中,观察到了 AEF。其他患者的诊断依据是左心循环或纵隔中有空气。在 14/26 例患者中,食管胃镜检查导致肺功能恶化。共有 41 名患者接受了食管手术(存活率为 76%),9 名患者仅接受了支架植入手术(存活率为 22%)。有 27 名患者未能及时得到诊断或治疗。如果患者在近期接受消融手术后出现发热或神经症状,则应怀疑是 AEF。胸部和头部 CT 扫描可为诊断提供支持。一旦确诊,应立即进行急诊手术,以防止进一步的并发症。应避免食管胃镜检查。 作者希望提供一份实用的管理指南,以便更早诊断、更快治疗,从而提高这些患者的生存率。
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引用次数: 0
Arbeidsongeschiktheid na liesbreukherstel: onderzoek naar het voorschrijfgedrag van huisartsen en chirurgen 腹股沟疝修补术后的残疾:全科医生和外科医生处方行为调查
Pub Date : 2024-05-14 DOI: 10.47671/tvg.80.24.031
A. Dams, M. Du Bois
Incapacity for work after inguinal hernia repair: survey of general practitioners’ and surgeons’ prescribing behaviour Inguinal hernia surgery is a very frequently performed procedure. Since this pathology often presents in professionally active patients, the procedure and resulting incapacitation have socio-economic repercussions. Additionally, a laparoscopic repair has become the standard procedure, a technique that involves significant additional costs. The aim of this study was to investigate the period of incapacity after a uni- or bilateral, open or laparoscopic repair, prescribed by GPs and surgeons, as well as their main motivations. A survey was sent to 17 GP associations in the province of Limburg (Belgium) with the request to distribute it to their members. Additionally, 73 abdominal surgeons were asked to complete the same survey. The prescription behaviour with regard to the incapacity period was evaluated as a function of the surgical technique used and the type of physical exertion required during professional practice or sports. The motivation for this prescribing behaviour was also surveyed. 107 GPs and 35 surgeons fully completed the survey. It demonstrated a wide variation in the prescribing behaviour. There was no correlation with the years of professional experience. The average prescribed incapacity period was significantly higher among GPs than surgeons. Hardly any distinction was made between a uni- and bilateral recovery. Avoidance of recurrences was the most frequently mentioned factor determining the prescribing behaviour among both GPs (89.9%) and surgeons (79.4%). The survey reveals a lack of consensus regarding the prescribing behaviour in primary and secondary care. This is mainly based on fear of recurrence, which is unfounded. Developing evidence-based postoperative guidelines for the return to work and to the normal activities is recommended.
腹股沟疝修补术后丧失工作能力:全科医生和外科医生处方行为调查 腹股沟疝手术是一种非常常见的手术。由于这种病症通常发生在从事职业活动的患者身上,因此手术和由此导致的丧失工作能力会对社会经济产生影响。此外,腹腔镜修补术已成为标准手术,但这项技术需要大量额外费用。本研究旨在调查全科医生和外科医生开具的单侧或双侧、开腹或腹腔镜修复术后丧失工作能力的时间,以及他们的主要动机。我们向林堡省(比利时)的 17 个全科医生协会发送了调查问卷,并要求他们向其成员分发。此外,还要求 73 名腹部外科医生完成同样的调查。根据所使用的手术技术以及专业实践或体育运动中所需的体力消耗类型,对丧失工作能力期间的处方行为进行了评估。此外,还对这种处方行为的动机进行了调查。107 名全科医生和 35 名外科医生全部完成了调查。调查显示,处方行为差异很大。与专业经验的年限没有关联。全科医生开出的丧失工作能力处方的平均期限明显高于外科医生。单侧恢复和双侧恢复几乎没有区别。避免复发是全科医生(89.9%)和外科医生(79.4%)最常提及的决定处方行为的因素。调查显示,初级和二级医疗机构对处方行为缺乏共识。这主要是基于对复发的恐惧,而这种恐惧是毫无根据的。建议制定以证据为基础的术后重返工作和正常活动指南。
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引用次数: 0
Hepatisch portaal veneus gas in combinatie met pneumatosis intestinalis op basis van dunnedarmischemie 基于小肠缺血的肝门静脉积气合并肠气肿
Pub Date : 2024-05-10 DOI: 10.47671/tvg.80.24.027
C. Boels, R. Schoonjans, D. Fonck, B. Van Imschoot, A. Van Driessche
Hepatic portal venous gas in combination with pneumatosis intestinalis based on small-bowel ischemia: a case-report A 76-year-old man presented with complaints of abdominal pain and vomiting. An urgent CT scan showed pneumatosis intestinalis of the small intestine with air in the portal vein and the portal venules of the left hepatic lobe. Hepatic portal venous gas is a rare radiological finding: gas is found in the portal venous branches. This can be seen in both benign and life-threatening conditions. In most cases, it is accompanied by underlying intestinal ischemia, which was also the case in this patient. The patient underwent urgent surgery with a partial resection of the small intestine. After a brief admission to the intensive care unit, the man recovered well and was able to leave the hospital in good health.
肝门静脉积气合并小肠缺血引起的肠积气:病例报告 一名 76 岁的男子因腹痛和呕吐前来就诊。紧急 CT 扫描显示小肠气肿,门静脉和左肝叶门静脉内有空气。肝门静脉积气是一种罕见的放射学发现:气体存在于门静脉分支中。这种情况既可见于良性疾病,也可见于危及生命的疾病。大多数情况下,门静脉积气伴有潜在的肠缺血,该患者的情况也是如此。患者接受了小肠部分切除的紧急手术。在重症监护室短暂住院后,该男子恢复良好,可以健康出院。
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引用次数: 0
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