{"title":"Magnitude of precancerous cervical lesions induced by human papillomavirus subtypes 16 and 18 and associated factors among affected women","authors":"Mamaru Getinet, Mohammed Jemal, Temesgen Baylie, Enyew Fenta, Habtamu Belew, Gashaw Azanaw, Adane Adugna, Bantayehu Addis","doi":"10.3892/wasj.2024.269","DOIUrl":"https://doi.org/10.3892/wasj.2024.269","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"44 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of a novel high‑risk HPV‑16/18 therapeutic vaccine in treating cervical intraepithelial neoplasia and cervical cancer in a clinical trial: A systematic review and meta‑analysis","authors":"Zigale Teffera, Wubetu Yihunie, B. Tegegne, Bewuket Misganaw, D. Abebaw, Mekuriaw Belayineh, Yibeltal Akelew, Tebelay Dilnesa, Adane Adugna, Banteizie Silabat, Samrawit Tefera, Habtamu Belew, Lealem Bimrew","doi":"10.3892/wasj.2024.267","DOIUrl":"https://doi.org/10.3892/wasj.2024.267","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"15 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141814773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thanh Do, Phuong Pham, Phuong Nguyen, Anh Pham, Ha Vu
{"title":"Malnutrition and micronutrient deficiency following gastrointestinal cancer surgery: A case report and mini‑review of the literature","authors":"Thanh Do, Phuong Pham, Phuong Nguyen, Anh Pham, Ha Vu","doi":"10.3892/wasj.2024.266","DOIUrl":"https://doi.org/10.3892/wasj.2024.266","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"45 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rawa Ali, Omar Hawramy, Deari Esmaeil, Dana Gharib, Soran H. Tahir, D. Ahmed, Hemn Ali, Karokh Hussein, Rebaz Ali, Berun A. Abdalla, Fahmi H. Kakamad, Hevar A. Azaldeen
{"title":"Primary pancreatic hydatid cyst: A case report and a brief review of the literature","authors":"Rawa Ali, Omar Hawramy, Deari Esmaeil, Dana Gharib, Soran H. Tahir, D. Ahmed, Hemn Ali, Karokh Hussein, Rebaz Ali, Berun A. Abdalla, Fahmi H. Kakamad, Hevar A. Azaldeen","doi":"10.3892/wasj.2024.264","DOIUrl":"https://doi.org/10.3892/wasj.2024.264","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"125 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141665603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of angiotensin‑converting enzyme inhibitors in gynecological cancers: Pathways and mechanisms involved (Review)","authors":"Roland Lengkey, Ray Soetadji, Ardo Sanjaya","doi":"10.3892/wasj.2024.263","DOIUrl":"https://doi.org/10.3892/wasj.2024.263","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":" August","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
. Malignant melanoma is a skin tumor with a poor prognosis. Therefore, it is critical to explore the risk factors associated with the outcome of this tumor. In the present study, Mendelian randomization (MR) was used to investigate the causal association between cathepsins and malignant melanoma. Summary statistical data on five cathepsins from European participants were extracted as exposure data. Data on melanoma from a genome‑wide association study of European ancestry were used as outcome data. Single nucleotide polymorphisms associated with cathepsins were used as instrumental variables (IVs). In a genome‑wide association study of malignant melanoma including 3,751 melanoma cases and 372,016 European ancestry controls, MR analysis was conducted to examine the effects of these IVs on melanoma. The inverse variance‑weighted method was used for MR analysis. In addition, MR‑Egger, weighted median and MR pleiotropy residual sum were used for complemen‑ tary analyses. Furthermore, a series of sensitivity analyses were performed to ensure the validity and robustness of the results. The gene‑predicted results indicated no causal asso‑ ciation between the five cathepsins and malignant melanoma (P>0.05). Cathepsin S [odds ratio (OR), 1.000; 95% confidence interval (CI), 0.999‑1.001; P=0.943], cathepsin B (OR, 1.000; 95% CI, 0.999‑1.001; P=0.763), cathepsin O (OR, 1.000; 95% CI, 0.999‑1.001; P=0.646), cathepsin E (OR, 0.999; 95% CI, 0.998‑1.001; P=0.375) and cathepsin L2 (OR, 1.101; 95% CI, 0.831‑1.458; P=0.503) were not significantly associated with the risk of developing melanoma. Sensitivity analysis demonstrated no significant bias in the aforementioned results.
{"title":"Mendelian randomization study of the association between cathepsins and melanoma","authors":"Wenwen Wang, Jun Li","doi":"10.3892/wasj.2024.262","DOIUrl":"https://doi.org/10.3892/wasj.2024.262","url":null,"abstract":". Malignant melanoma is a skin tumor with a poor prognosis. Therefore, it is critical to explore the risk factors associated with the outcome of this tumor. In the present study, Mendelian randomization (MR) was used to investigate the causal association between cathepsins and malignant melanoma. Summary statistical data on five cathepsins from European participants were extracted as exposure data. Data on melanoma from a genome‑wide association study of European ancestry were used as outcome data. Single nucleotide polymorphisms associated with cathepsins were used as instrumental variables (IVs). In a genome‑wide association study of malignant melanoma including 3,751 melanoma cases and 372,016 European ancestry controls, MR analysis was conducted to examine the effects of these IVs on melanoma. The inverse variance‑weighted method was used for MR analysis. In addition, MR‑Egger, weighted median and MR pleiotropy residual sum were used for complemen‑ tary analyses. Furthermore, a series of sensitivity analyses were performed to ensure the validity and robustness of the results. The gene‑predicted results indicated no causal asso‑ ciation between the five cathepsins and malignant melanoma (P>0.05). Cathepsin S [odds ratio (OR), 1.000; 95% confidence interval (CI), 0.999‑1.001; P=0.943], cathepsin B (OR, 1.000; 95% CI, 0.999‑1.001; P=0.763), cathepsin O (OR, 1.000; 95% CI, 0.999‑1.001; P=0.646), cathepsin E (OR, 0.999; 95% CI, 0.998‑1.001; P=0.375) and cathepsin L2 (OR, 1.101; 95% CI, 0.831‑1.458; P=0.503) were not significantly associated with the risk of developing melanoma. Sensitivity analysis demonstrated no significant bias in the aforementioned results.","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"101 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A single‑office experience of day‑case water vapor thermal therapy for benign prostatic hyperplasia","authors":"Takashi Okabe","doi":"10.3892/wasj.2024.249","DOIUrl":"https://doi.org/10.3892/wasj.2024.249","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of clinical examination in the evaluation of patients with breast lumps: A cytopathological study","authors":"Santosh Sharma, Sompal Singh, Sanjay Kumar","doi":"10.3892/wasj.2024.248","DOIUrl":"https://doi.org/10.3892/wasj.2024.248","url":null,"abstract":"","PeriodicalId":507643,"journal":{"name":"World Academy of Sciences Journal","volume":"5 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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