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An unusual cause of anterior wall ST-elevation myocardial infarction: A case report 前壁 ST 段抬高型心肌梗死的一个不寻常病因:病例报告
Pub Date : 2024-05-14 DOI: 10.1093/ehjcr/ytae243
Z. Dindane, Elena Golgor, Axel Linke, N. Mangner
Metastatic tumors, notably lung cancer, can cause conditions resembling acute myocardial infarctions (AMI), contributing to the minor percentage of AMIs unrelated to coronary atherosclerosis. These instances necessitate specialized diagnostic and therapeutic approaches due to the distinct underlying pathology. We report a case of a 65-year-old male with metastatic lung cancer presenting with prolonged angina pectoris. Elevated troponin and creatine kinase levels led to emergency catheterization, revealing a total occlusion of the distal Left Coronary Artery (LCA) attributed to tumor infiltration. Intervention attempts were unsuccessful, and given the palliative context, other revascularization strategies were not pursued. Two-dimensional Transthoracic Echocardiogram (TTE) depicted tumor invasion at the heart’s apex, confirming the diagnosis. The patient passed away shortly after receiving palliative radiation therapy. This case underscores the challenges in diagnosing and managing myocardial infiltrations from metastatic tumors mimicking AMI. It accentuates the importance of imaging studies for accurate diagnosis and the critical evaluation of intervention strategies, highlighting the need for focused palliative care in such complex scenarios.
转移性肿瘤,尤其是肺癌,可引起类似急性心肌梗死(AMI)的症状,在与冠状动脉粥样硬化无关的急性心肌梗死中所占比例很小。由于这些病例的病理基础不同,因此必须采用专门的诊断和治疗方法。 我们报告了一例 65 岁男性转移性肺癌患者的病例,患者表现为长期心绞痛。肌钙蛋白和肌酸激酶水平升高导致患者接受了急诊导管检查,结果显示远端左冠状动脉(LCA)因肿瘤浸润而完全闭塞。介入治疗尝试未获成功,考虑到是姑息治疗,因此没有采取其他血管再通策略。二维经胸超声心动图(TTE)显示肿瘤侵犯心尖,从而确诊了这一诊断。患者在接受姑息放疗后不久去世。 该病例强调了在诊断和处理模仿 AMI 的转移性肿瘤心肌浸润时所面临的挑战。它强调了影像学研究对准确诊断和干预策略关键评估的重要性,突出了在这种复杂情况下进行重点姑息治疗的必要性。
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引用次数: 0
Branch retinal artery occlusion with non-obstructive general angioscopy confirmed puff-chandelier rupture releasing cholesterol crystals in the aortic arch: a case report 视网膜分支动脉闭塞伴非阻塞性全身血管造影证实主动脉弓内释放胆固醇结晶的 "噗嗤 "破裂:病例报告
Pub Date : 2024-05-10 DOI: 10.1093/ehjcr/ytae238
Shohei Migita, K. Kojima, Yasuo Okumura
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引用次数: 0
Aortic Valve Laceration Following Rotational Atherectomy: A Case Report 旋转动脉粥样硬化切除术后的主动脉瓣撕裂:病例报告
Pub Date : 2024-05-09 DOI: 10.1093/ehjcr/ytae226
Farrah Othman, Gerald Yong, Alan Whelan, A. Ihdayhid
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引用次数: 0
“Unveiling the Complexity: Coexistence of Rheumatic Heart Disease and Pulmonary Arteriovenous Malformation - A Unique Case Report” "揭开复杂的面纱:风湿性心脏病与肺动静脉畸形并存--一份独特的病例报告"
Pub Date : 2024-05-09 DOI: 10.1093/ehjcr/ytae239
R. Charaniya, Jayal Shah, Apoorva M
The coexistence of Rheumatic Heart Disease (RHD) and Pulmonary Arteriovenous Malformation (PAVM) is a rare clinical scenario that poses diagnostic and therapeutic challenges. This case report explores the clinical presentation, diagnostic journey, and multidisciplinary management of a patient presenting with both conditions. A 47-year-old female with a history of RHD presented with symptoms of dyspnoea on exertion and cyanosis, suggestive of both cardiac and pulmonary involvement. Subsequent investigations involving imaging, echocardiography, and invasive pulmonary angiography, revealed the co-existence of RHD and multiple PAVM in patient’s left lower lobe of lung. The patient underwent a tailored treatment plan, initially involving percutaneous mitral balloon valvuloplasty for RHD, followed by a staged procedure of transcatheter PAVM closure with Amplatzer™ Vascular Plug II performed one month later. Her saturation normalized following intervention. The patient's progress was monitored closely, with adjustments made to the treatment plan based on evolving clinical scenarios. Patient remained well in short term follow up. This case highlights the complexity of managing patients having two diverse conditions RHD and PAVM coexisting together, thus emphasizing the importance of a multidisciplinary approach. The unique intersection of cardiac and pulmonary pathologies necessitates careful consideration of diagnostic nuances and tailored treatment strategies. Lessons learned from this case offer valuable insights for clinicians encountering similar scenarios and underscore the significance of individualized, patient-centred care in optimizing outcomes for those with dual pathologies.
风湿性心脏病(RHD)和肺动静脉畸形(PAVM)并存是一种罕见的临床症状,给诊断和治疗带来了挑战。本病例报告探讨了一名同时患有这两种疾病的患者的临床表现、诊断过程和多学科管理。 一名 47 岁的女性患者曾患急性心肌梗死(RHD),出现用力时呼吸困难和发绀症状,提示心脏和肺部均受累。随后进行的影像学、超声心动图和有创肺动脉造影检查显示,患者的左肺下叶同时存在RHD和多发性海绵状血管瘤。患者接受了量身定制的治疗方案,首先是经皮二尖瓣球囊瓣膜成形术治疗 RHD,然后在一个月后使用 Amplatzer™ Vascular Plug II 分阶段进行经导管 PAVM 封堵术。介入治疗后,她的饱和度恢复正常。患者的病情进展得到了密切监测,并根据不断变化的临床情况对治疗方案进行了调整。在短期随访中,患者的情况依然良好。 该病例突出了管理同时患有 RHD 和 PAVM 两种不同疾病的患者的复杂性,从而强调了多学科方法的重要性。心脏和肺部病理的独特交汇点需要仔细考虑诊断上的细微差别和量身定制的治疗策略。从这个病例中汲取的经验为临床医生在遇到类似情况时提供了宝贵的启示,并强调了以患者为中心的个性化护理对优化双重病理患者的治疗效果的重要意义。
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引用次数: 0
Collateral beauty: Left main stem atresia 侧面美左主干闭锁
Pub Date : 2024-05-08 DOI: 10.1093/ehjcr/ytae241
S. Ranchordás, A. Vazão, Francisco Soares, Marta Marques
A 53-year-old man with no ischemic cardiac symptoms but dynamic ventricular repolarization changes in Holter monitoring underwent cardiac investigation prior to elective non cardiac surgery. Invasive coronary angiography followed by computed tomography coronary angiography showed left main stem atresia with collaterals from the right coronary artery supplying retrogradely the left coronary circulation. The echocardiogram showed no alterations. Cardiac magnetic resonance myocardial perfusion imaging showed no ischemia. During the 18-month follow-up period, the patient remained asymptomatic for ischemic events and therefore no intervention was deemed necessary.
一名 53 岁的男子没有心脏缺血性症状,但在 Holter 监测中出现动态心室复极化变化,因此在择期进行非心脏手术前接受了心脏检查。有创冠状动脉造影和计算机断层扫描冠状动脉造影显示左主干闭锁,右冠状动脉袢逆行供应左冠状动脉循环。超声心动图未显示任何改变。心脏磁共振心肌灌注成像显示没有缺血。在 18 个月的随访期间,患者一直没有缺血症状,因此无需进行干预。
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引用次数: 0
A case report of ATTR-amyloidosis following cardiac transplantation: thick ventricles that look alike 心脏移植后的 ATTR 淀粉样变性病例报告:看起来很像的厚心室
Pub Date : 2024-05-08 DOI: 10.1093/ehjcr/ytae242
Charlotte Lauwers, T. Rosseel, W. Droogné, L. V. Van Aelst, J. Van Cleemput
Transthyretin (ATTR-) amyloidosis is more prevalent than initially thought. As much as 13% of patients hospitalized with HFpEF may have ATTR-cardiomyopathy (CM). Conversely, heart transplant patients may manifest left ventricular hypertrophy or diastolic dysfunction, especially late after transplantation. We present a case of a 82-year old male heart transplant patient, 31 years following orthotopic heart transplantation. While he was satisfied with his exercise capacity as an octogenarian, several years before he required pacemaker implantation due to 3rd degree AV block, had bilateral carpal tunnel syndrome treated with carpal tunnel release surgery and experienced idiopathic sudden deafness. Based on increasing left ventricular wall thickness during routine follow-up, a diagnosis of ATTR-amyloidosis was suspected. Ultimately, the diagnosis was confirmed non-invasively with a specific scintigraphic exam, while an additional physicochemical stain on an endomyocardial biopsy taken several years before provided pathological proof. We initiated tafamidis, yet stopped this treatment after one month because of gastro-intestinal intolerance. Ultimately, our patient died two years later due to heart failure. Our case shows the long delay between the onset of transthyretin deposition, the presence of clinical signs and the final diagnosis. Echocardiographic findings suggestive for ATTR-CM include left ventricular hypertrophy and diastolic dysfunction, which are both common in heart transplant patients. Yet, ATTR-CM should be considered in the differential diagnosis, especially late after transplantation, in this closely monitored population.
转甲状腺素(ATTR)淀粉样变性比最初想象的更为普遍。多达 13% 的高频心衰住院患者可能患有 ATTR 心肌病 (CM)。相反,心脏移植患者可能表现出左心室肥厚或舒张功能障碍,尤其是在移植后晚期。 我们介绍了一例 82 岁的男性心脏移植患者的病例,他在接受正位心脏移植手术 31 年后出现了左心室肥厚或舒张功能障碍。虽然他对自己作为八旬老人的运动能力感到满意,但几年前他因三度房室传导阻滞而需要植入起搏器,并接受了双侧腕管综合征的腕管松解手术治疗,还出现了特发性突发性耳聋。根据常规随访期间左心室壁厚度增加的情况,他被怀疑诊断为 ATTR 淀粉样变性病。最终,通过特殊的闪烁成像检查无创确诊,而几年前的心内膜活检的附加理化染色提供了病理证据。我们开始使用他非米迪,但一个月后因胃肠道不耐受而停止了治疗。最终,我们的病人在两年后死于心力衰竭。 我们的病例表明,从转甲状腺素沉积开始、出现临床症状到最终确诊之间的时间间隔很长。提示 ATTR-CM 的超声心动图检查结果包括左心室肥厚和舒张功能障碍,这在心脏移植患者中很常见。然而,在对这一人群进行密切监测时,应将 ATTR-CM 考虑在鉴别诊断中,尤其是移植后晚期。
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引用次数: 0
A Rare Case Report of an Acquired Aorto-Pulmonary Artery Fistula after Bentall Procedure: Multimodality Imaging Approach may be the Key? 本托尔手术后获得性主动脉-肺动脉瘘的罕见病例报告:多模式成像方法可能是关键?
Pub Date : 2024-05-07 DOI: 10.1093/ehjcr/ytae236
Monica Barki, S. Sacchi, Cecilia Marcolin, S. Ajello, A. Scandroglio
The acquired communication between the aorta and the pulmonary artery is a rare and potentially life-threatening condition. Its diagnosis is challenging and may require a multimodality imaging approach. A 67-year-old Caucasian man, admitted for acute respiratory failure unresponsive to medical therapy and non-invasive ventilation, was diagnosed with an aorto-pulmonary fistula (APF) complicating a pseudoaneurysm of the aortic root. This condition developed after Bentall cardiac surgery, which entailed the use of a straight Dacron aortic graft coupled with a mechanical prosthesis. A multimodal imaging approach, combining echocardiography and computed tomography angiography, was diagnostic and supported the development of a surgical treatment strategy. The patient underwent successful surgical closure of the APF and correction of the aortic pseudoaneurysm. Aorto-pulmonary fistula can result in rapid clinical deterioration if left untreated. The combination of echocardiography and computed tomography angiography techniques allowed for the diagnosis and surgical correction of the APF.
主动脉和肺动脉之间的后天沟通是一种罕见的、可能危及生命的疾病。其诊断具有挑战性,可能需要采用多模态成像方法。 一名 67 岁的白种男子因对药物治疗和无创通气无效的急性呼吸衰竭入院,被诊断为主动脉根部假性动脉瘤并发主动脉肺瘘 (APF)。这种情况是在本塔尔心脏手术后出现的,手术中使用了带机械假体的直达克隆主动脉移植物。结合超声心动图和计算机断层扫描血管造影术的多模态成像方法具有诊断作用,有助于制定手术治疗策略。患者成功地接受了主动脉肺动脉瘘闭合手术和主动脉假性动脉瘤矫治手术。 如果不及时治疗,主动脉-肺动脉瘘会导致临床病情迅速恶化。结合超声心动图和计算机断层扫描血管造影技术,可以诊断并通过手术矫正 APF。
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引用次数: 0
Use of Cangrelor for Complex Percutaneous Coronary Intervention in the Context of Concomitant Severe Aortic Stenosis: a case series 在伴有严重主动脉瓣狭窄的情况下使用 Cangrelor 进行复杂的经皮冠状动脉介入治疗:一个病例系列
Pub Date : 2024-05-06 DOI: 10.1093/ehjcr/ytae237
Francesco Soriano, Andrea R. Munafò, Nurcan Baydaroglun, Stefano Nava, Giuseppe Bruschi, Giuseppe Esposito, J. Oreglia, Claudio Montalto
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引用次数: 0
Cardiovascular Magnetic Resonance in the Identification of Extra-Cardiac Causes of Myocarditis: a case series 心血管磁共振在心肌炎心外病因鉴定中的应用:一个病例系列
Pub Date : 2024-05-06 DOI: 10.1093/ehjcr/ytae232
H. Sakhi, Guillaume Reverdito, G. Soulat, É. Mousseaux
Myocarditis is challenging to diagnose due to its varied presentations. Endomyocardial biopsy is the gold standard for diagnosis, but its invasive nature has led to alternative non-invasive modalities, notably Cardiovascular Magnetic Resonance (CMR). Identifying the precise etiology of myocarditis is crucial for effective treatment, yet extra-cardiac causes are often overlooked. In this paper, we spotlight the underexplored role of CMR in diagnosing extra-cardiac etiologies, utilizing three insightful cases for illustration. The first case is a 31-year-old patient with myocarditis secondary to a pyogenic liver abscess, identified through CMR who improved after abscess drainage. The second case involves a 54-year-old patient with myocarditis attributed to adult T-cell leukemia-lymphoma, with the loco-regional thickening process identified thanks to CMR. This patient had an unfavorable disease progression due to the underlying malignancy. The third case concerns a 23-year-old patient suffering from myocarditis due to pneumonia, again illustrated effectively through CMR imaging and who recovered after antibiotic treatment. These cases underline the overlooked potential of CMR in diagnosing extra-cardiac etiologies of myocarditis, even though such causes are rare. Despite current guidelines recognizing the importance of identifying the etiology of myocarditis, they do not explicitly address the role of CMR in diagnosing extra-cardiac etiologies. Therefore, this article proposes that future guidelines could emphasize the utility of CMR in exploring these causes, potentially leading to more accurate diagnoses and improving patient outcomes. It also advocates for a comprehensive, multidisciplinary approach to myocarditis diagnosis, encouraging vigilance for potential loco-regional causes, and calls for further research in this area.
心肌炎的表现多种多样,因此诊断具有挑战性。心内膜心肌活检是诊断的金标准,但由于其侵入性,人们开始采用其他非侵入性方法,特别是心血管磁共振(CMR)。确定心肌炎的确切病因对有效治疗至关重要,但心外病因往往被忽视。在本文中,我们将利用三个有说服力的病例来说明 CMR 在诊断心外病因方面尚未被充分开发的作用。 第一个病例是一名继发于化脓性肝脓肿的 31 岁心肌炎患者,通过 CMR 发现,脓肿引流后病情有所好转。第二个病例是一名 54 岁的成人 T 细胞白血病-淋巴瘤心肌炎患者,CMR 发现了局部区域性增厚过程。由于潜在的恶性肿瘤,该患者的病情发展并不乐观。第三个病例涉及一名因肺炎引发心肌炎的 23 岁患者,CMR 成像再次有效地说明了这一情况,患者在接受抗生素治疗后痊愈。 这些病例强调了 CMR 在诊断心肌炎心外病因方面被忽视的潜力,尽管此类病因很少见。尽管目前的指南认识到确定心肌炎病因的重要性,但并未明确说明 CMR 在诊断心外病因中的作用。因此,本文建议未来的指南应强调 CMR 在探索这些病因方面的作用,从而有可能获得更准确的诊断并改善患者的预后。文章还提倡采用多学科综合方法诊断心肌炎,鼓励警惕潜在的局部区域性病因,并呼吁在这一领域开展进一步研究。
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引用次数: 0
High-Output Heart Failure due to a Giant Left Circumflex Coronary Aneurysm with a Left Atrial Fistula and Atrial Septal Defect: A Case Report 伴有左心房瘘和房间隔缺损的巨大左侧环状冠状动脉瘤导致的高输出量心力衰竭:病例报告
Pub Date : 2024-04-25 DOI: 10.1093/ehjcr/ytae171
Moses Lee, Mariam Thomas, Golsa Joodi, Anthony S. Koppula, Jonathan Soverow
A coronary artery aneurysm is a rare cardiac anomaly that may be incidentally detected on echocardiography. When associated with a coronary cameral fistula, an aneurysm can become symptomatic. We present a unique case of a giant left circumflex coronary aneurysm with a fistula to the left atrium and a large atrial septal defect causing acute heart failure in a young woman during the peripartum period. A 33 year-old woman who presented with hypoxia after the delivery of her fourth child was found to have heart failure with severe mitral regurgitation and multiple abnormal intracardiac shunts. Echocardiography showed a large circular structure with Doppler color flow into the left atrium and between the atria. Cardiac computed tomography showed multiple dilated coronary arteries including a left circumflex coronary artery aneurysm measuring greater than 10 cm in diameter with fistulous communication to the left atrium and a large atrial septal defect. A right heart catheterization was performed and the patient was diagnosed with high-output heart failure. Surgical closure of the coronary cameral fistula was deferred due to risk of worsening pressure in the coronary aneurysm and the patient was referred for cardiac transplantation. This case illustrates severe heart failure as a complication of a giant coronary artery aneurysm with fistulization to the left atrium and subsequent shunting through a large atrial defect. Echocardiography allows for detection of a coronary aneurysm and shunting and cardiac computed tomography provides detailed visualization of a coronary cameral fistula.
冠状动脉瘤是一种罕见的心脏畸形,可在超声心动图检查中偶然发现。当动脉瘤伴有冠状动脉瘘时,可能会出现症状。我们介绍了一例独特的病例,一名年轻女性在围产期因巨大的左侧环状冠状动脉瘤伴有通往左心房的瘘管和巨大的房间隔缺损而导致急性心力衰竭。 一名 33 岁的妇女在分娩第四个孩子后出现缺氧,被发现患有心力衰竭,伴有严重的二尖瓣返流和多个异常的心内分流。超声心动图显示,多普勒彩色血流进入左心房和心房之间有一个巨大的圆形结构。心脏计算机断层扫描显示多条扩张的冠状动脉,包括一个直径超过 10 厘米的左侧冠状动脉周动脉瘤,该动脉瘤与左心房有瘘管相通,并有一个巨大的房间隔缺损。患者接受了右心导管检查,被诊断为高输出性心力衰竭。由于冠状动脉瘤内压力恶化的风险,冠状动脉瘘的手术闭合被推迟,患者被转诊至心脏移植。 本病例说明了巨大冠状动脉瘤并发严重心力衰竭,瘘管通向左心房,随后通过巨大的心房缺损分流。超声心动图可检测出冠状动脉瘤和分流,心脏计算机断层扫描可提供冠状动脉瘘的详细图像。
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引用次数: 0
期刊
European Heart Journal - Case Reports
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