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Méthodologie de l'étude repair et description des populations 修复研究方法和种群描述
Pub Date : 2007-03-01 DOI: 10.1016/S0003-4401(07)80007-6
D. Chevallier , A. Descazeaud

The Repair study included 535 French urologists. All of them answered to a general information questionnaire. Then, they had to complete a questionnaire for each of the 10 first radical prostatectomy patients they saw in consultation and who were operated in the last 12 months. Overall, 2445 patient questionnaires were completed by the urologists. In addition, 2644 self-questionnaires were completed by the patients at home and sent to the TNS SOFRES Company. All questionnaires contained information regarding the incidence and the management of urinary and sexual disorders following radical prostatectomy.

Repair研究包括535名法国泌尿科医生。所有人都回答了一份一般信息问卷。然后,他们必须完成一份问卷,调查他们在咨询中见到的10名首次根治性前列腺切除术患者,这些患者在过去12个月内接受了手术。泌尿科医生共完成了2445份患者问卷。另外,患者在家完成2644份自填问卷,并寄至TNS SOFRES公司。所有问卷都包含根治性前列腺切除术后泌尿系统和性功能障碍的发生率和管理信息。
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引用次数: 0
Dysfonction érectile apèr s prostatectomie totale : incidence, attente et vécu des patients 全前列腺切除术后勃起功能障碍:患者的发生率、期望和生活经历
Pub Date : 2007-03-01 DOI: 10.1016/S0003-4401(07)80009-X
O. Montaigne , A. Descazeaud

The Repair study contains many data regarding the incidence of erectile dysfunction following radical prostatectomy, and the point of view of patients who undergo sexual disorders. First, it appears that 80% of patients are given information by their urologist before surgery about sexual consequences of radical prostatectomy. During the three months before surgery, 92% and 75% of patients who completed the questionnaires have had erections and sexual intercourse, respectively. Using the laparoscopic approach or the open technique for radical prostatectomy appears not to influence the incidence of erectile dysfunction following surgery that is 92%. Contrary to what the urologists report in the questionnaires, the patients consider erectile dysfunction more important than urinary disorders. In addition, 61% of patients report that they would like to be treated for erectile dysfunction during the first three months following surgery, which is earlier than the urologists consider. Finally, it appears in the Repair study that erectile function recovery is easier when patients are managed early after surgery for their sexual disorders.

修复研究包含了许多关于根治性前列腺切除术后勃起功能障碍发生率的数据,以及患有性功能障碍的患者的观点。首先,80%的患者在手术前泌尿科医生会告诉他们根治性前列腺切除术对性行为的影响。在手术前的三个月里,92%和75%完成问卷调查的患者分别有过勃起和性交。采用腹腔镜或开放式技术进行根治性前列腺切除术似乎不会影响术后勃起功能障碍的发生率(92%)。与泌尿科医生在问卷中的报告相反,患者认为勃起功能障碍比泌尿系统疾病更重要。此外,61%的患者报告说,他们希望在手术后的前三个月接受勃起功能障碍治疗,这比泌尿科医生认为的要早。最后,在Repair研究中,如果患者在性功能障碍手术后及早处理,勃起功能恢复会更容易。
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引用次数: 1
Prise en charge des troubles de I'érection après prostatectomie totale : la place prépondérante des injections intracaverneuses 全前列腺切除术后勃起障碍的治疗:腔内注射的优势
Pub Date : 2007-03-01 DOI: 10.1016/S0003-4401(07)80010-6
F. Giuliano , A. Descazeaud

Here is reported the main data contained in the Repair study regarding the management of sexual disorders following radical prostatectomy by French urologists. 20% of urologists do not evaluate the sexual function of their patient prior surgery. All urologists who participated to the study report that they take care of erectile dysfunction following radical prostatectomy. 38% of them have a systematical approach for the management of erectile dysfunction following surgery. 80% of urologists start their management of sexual disorders during the first 3 months following surgery, and 88% of them always use the same protocol. In 76% of cases, this protocol consists in the administration of intracavernous injections. The early administration of erectile dysfunction treatments is frequently used by the urologists. Finally, it appears in the Repair study that erectile dysfunction treatment is better accepted by patients when given early and systematically after surgery.

以下是法国泌尿科医生关于根治性前列腺切除术后性功能障碍管理的修复研究中的主要数据。20%的泌尿科医生在手术前不评估患者的性功能。所有参与研究的泌尿科医生都报告说,他们在根治性前列腺切除术后治疗了勃起功能障碍。其中38%的人有系统的方法来处理手术后的勃起功能障碍。80%的泌尿科医生在手术后的前3个月开始处理性功能障碍,其中88%的人总是使用相同的方案。在76%的病例中,该方案包括进行海绵内注射。泌尿科医生经常使用勃起功能障碍的早期治疗。最后,在Repair研究中,勃起功能障碍的治疗在手术后早期和系统地给予患者更好的接受度。
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引用次数: 0
Infertilité masculine : stratégie de la prise en charge 男性不孕症:管理策略
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.12.003
J. Schlosser , I. Nakib , F. Carré-Pigeon , F. Staerman

Although the objective of the urologist is to correct the factors of male infertility and to favour natural procreation, the strategy must consider also the couple and the female aspects of infertility. Some types of male infertility require specific treatment. In severe cases, recent advances in medical assistance to procreation have changed the prognosis of male infertility. Pregnancy can be obtained by the means of gamet manipulation and spermatozoid selection. Nevertheless, such techniques expose to genetic disorders transmission. Subsequently, genetic assessment is required during male infertility management, especially for difficult cases.

虽然泌尿科医生的目标是纠正男性不育的因素,有利于自然生殖,但该策略也必须考虑夫妇和女性不育方面。某些类型的男性不育症需要特殊治疗。在严重的情况下,生殖方面的医疗援助的最新进展改变了男性不育症的预后。通过配子操纵和精子选择可以获得妊娠。然而,这些技术暴露了遗传疾病的传播。因此,在男性不育症的治疗过程中需要进行遗传评估,特别是对于困难的病例。
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引用次数: 5
Traitement du prolapsus du dôme vaginal par sacrocolpopexie laparoscopique assistée par robot 机器人辅助腹腔镜骶结肠切除术治疗阴道圆顶脱垂
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.12.001
D.-S. Elliott MD, G.-K. Chow MD

Transabdominal sacrocolpopexy offers an excellent definitive treatment option for patients with high grade vaginal vault prolapse with long-term success rates ranging from 93-99 %. However, because it is a transabdominal procedure it is associated with increased morbidity compared with vaginal repairs. We describe a novel minimally invasive technique of vaginal vault prolapse repair and present out initial experience. The surgical technique involves placement of five laparoscopic ports: three for the Da Vinci ® robot and two for the assistant. A polypropylene mesh is then attached to the sacral promontory and to the vaginal apex using Gortex sutures. At the end of the case, the mesh material is the covered by the peritoneum. We also present our initial experience with this technique in 18 consecutive patients. The analysis focused on complications, urinary continence, patient satisfaction, and morbidity. Follow-up was conducted by provider-patient interview. Twenty-five patients underwent a robotic-assisted laparoscopic sacrocolpopexy at our institution in the past 24 months for severe symptomatic vaginal vault prolapse. 10/25 (40 %) underwent a concomitant anti-incontinence procedure. Mean follow-up was 5. (1-12) months and mean age was 66 (47-82) years. Mean total operative time was 3.2 (2.25-4.75) hours. One patient had to be converted to an open procedure secondary to unfavorable anatomy. All but one patient were discharged from the hospital after an overnight stay; one patient left on postoperative day #2. Complications were limited to mild port site infections in two patients, which resolved with oral antibiotic therapy. One patient developed recurrent grade 3 rectocele, but had no evidence of cystocele or enterocele. We present a novel technique for vaginal vault prolapse repair that combines the advantages of open sacrocolpopexy with the decreased morbidity and improved cosmesis of laparoscopic surgery. It is associated with decreased hospital stay, low complication and conversion rates, and high patient satisfaction. While our early experience is encouraging, long-term data is needed to confirm these findings and establish longevity of the repair.

经腹骶colpop固定术为高度阴道穹窿脱垂患者提供了一种极好的明确治疗选择,长期成功率为93% - 99%。然而,由于它是经腹手术,与阴道修复相比,它的发病率更高。我们描述了一种新的微创阴道穹窿脱垂修复技术,并介绍了我们的初步经验。手术技术包括放置五个腹腔镜端口:三个用于达芬奇®机器人,两个用于助手。然后使用Gortex缝合线将聚丙烯网片连接到骶骨岬和阴道尖。在病例结束时,网状材料被腹膜覆盖。我们还介绍了我们在18例连续患者中使用该技术的初步经验。分析的重点是并发症、尿失禁、患者满意度和发病率。随访采用供方-患者访谈方式。在过去的24个月里,有25例患者因严重的症状性阴道穹窿脱垂在我院接受了机器人辅助腹腔镜骶colpop固定术。10/25(40%)接受了伴随的防尿失禁手术。平均随访5次。1 ~ 12个月,平均年龄66(47 ~ 82)岁。平均总手术时间为3.2(2.25 ~ 4.75)小时。一名患者因解剖结构不良不得不转行开放手术。除一名患者外,其余患者在住院过夜后均出院;术后第2天有1例患者出院。两例患者的并发症仅限于轻度端口感染,经口服抗生素治疗解决。1例患者复发3级直肠膨出,但没有膀胱膨出或肠膨出的证据。我们提出了一种新的阴道穹窿脱垂修复技术,该技术结合了开放式骶colpop固定术的优点,降低了发病率,改善了腹腔镜手术的美观性。它与住院时间缩短、并发症和转换率低以及患者满意度高有关。虽然我们的早期经验令人鼓舞,但需要长期的数据来证实这些发现并确定修复的寿命。
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引用次数: 12
Lymphomes de l'appareil urogénital 泌尿生殖系统淋巴瘤
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.10.002
P. Brice, E. de Kerviler

Lymphomas of the genitourinary tract represent rare tumours for which the diagnosis is crucial regarding the specificity of the treatment. The most frequent localisations are the kidney (solitary tumour or multiple nodules) and the testis; other sites of the genitourinary tract are uncommon. One of the main challenges is to obtain an appropriate immuno-histochemical diagnosis with a good staging which is necessary to adapt the therapeutic options. These are mostly based on chemotherapy (with immunotherapy in B-cell lymphomas), of which the intensity and number of cycles depend on initial prognosis factors.

泌尿生殖道淋巴瘤是一种罕见的肿瘤,其诊断对治疗的特异性至关重要。最常见的定位是肾脏(单发肿瘤或多发结节)和睾丸;泌尿生殖系统的其他部位不常见。其中一个主要的挑战是获得一个适当的免疫组织化学诊断与良好的分期,这是必要的适应治疗方案。这些大多是基于化疗(b细胞淋巴瘤的免疫治疗),其强度和周期数取决于最初的预后因素。
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引用次数: 7
Chirurgie conservatrice et hypothermie rénale : bases physiologiques et technique opératoire 保守手术与肾体温过低:生理基础和手术技术
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.12.004
M. Colombel, M. Timsit, L. Badet

The conservative management of kidney cancer is widely accepted as a therapeutic option for tumours measuring less than 4 cm or in case of underlying renal disease and solitary kidney. The functional and carcinologic success of this conservative treatment results from a radical resection of the tumour and a careful repair of the collecting system and selective ligature of the vessels. Kidney artery clamping is a key to reach these objectives. The cooling of the kidney preserves from warm ischemia and reperfusion lesions. In this review, we explain the physiological basis of warm ischemia induced kidney lesions due to the kidney artery clamping and the advantage of hypothermia. The surgical technique as described by Novick is detailed. This well standardized technique has the advantage of being reproducible and adaptable to all situations.

对于小于4厘米的肿瘤或潜在的肾脏疾病和单发肾,保守治疗是被广泛接受的治疗选择。这种保守治疗的功能和癌变成功源于肿瘤的根治性切除、收集系统的仔细修复和血管的选择性结扎。肾动脉夹持是实现这些目标的关键。肾的冷却保存了热缺血和再灌注损伤。在这篇综述中,我们解释了由于肾动脉夹持引起的热缺血肾损害的生理基础和低温的优势。诺维克详细描述了手术技术。这种标准化的技术具有可重复性和可适应所有情况的优点。
{"title":"Chirurgie conservatrice et hypothermie rénale : bases physiologiques et technique opératoire","authors":"M. Colombel,&nbsp;M. Timsit,&nbsp;L. Badet","doi":"10.1016/j.anuro.2006.12.004","DOIUrl":"10.1016/j.anuro.2006.12.004","url":null,"abstract":"<div><p>The conservative management of kidney cancer is widely accepted as a therapeutic option for tumours measuring less than 4 cm or in case of underlying renal disease and solitary kidney. The functional and carcinologic success of this conservative treatment results from a radical resection of the tumour and a careful repair of the collecting system and selective ligature of the vessels. Kidney artery clamping is a key to reach these objectives. The cooling of the kidney preserves from warm ischemia and reperfusion lesions. In this review, we explain the physiological basis of warm ischemia induced kidney lesions due to the kidney artery clamping and the advantage of hypothermia. The surgical technique as described by Novick is detailed. This well standardized technique has the advantage of being reproducible and adaptable to all situations.</p></div>","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.anuro.2006.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26584850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Aspects techniques de la préservation nerveuse au cours de la prostatectomie rétropubienne 耻骨后前列腺切除术中神经保存的技术方面
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.12.002
J. Walz , M. Graefen , U.H.G. Michl , H. Heinzer , M.G. Friedrich , C. Eichelberg , A. Haese , H. Huland

Retropubic radical prostatectomy is the most commonly used therapeutic option for the treatment of clinically localized prostate cancer. An ongoing stage migration towards organ-confined cancers allows performing a nerve-sparing procedure in a growing number of patients. Key elements for achieving convincing functional results are a sphincter preserving ligation of the distal part of Santorini's plexus and the subtle preparation of the neurovascular bundle. This article gives a detailed description of the operative technique. Furthermore, a strategy for patient selection and tumour selection for the indication of nerve-sparing radical prostatectomy (NSRP) is suggested.

耻骨后根治性前列腺切除术是临床上治疗局限性前列腺癌最常用的治疗方法。正在进行的向器官局限性癌症的阶段性迁移允许在越来越多的患者中进行神经保留手术。获得令人信服的功能结果的关键因素是保留圣托里尼神经丛远端部分的括约肌结扎和神经血管束的精细准备。本文详细介绍了手术技术。此外,对保留神经的根治性前列腺切除术(NSRP)的适应症的患者选择和肿瘤选择策略提出了建议。
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引用次数: 2
Traitement conservateur des tumeurs des voies excrétrices supérieures 上排泄途径肿瘤的保守治疗
Pub Date : 2007-02-01 DOI: 10.1016/j.anuro.2006.10.003
M.-E. Jabbour , A.-D. Smith

The histological appearance and the clinical behaviour of upper urinary tract urothelial tumours are almost identical to those of the bladder. Superficial papillary tumours rarely progress and turn to invasive disease despite a high frequency of recurrence. Technical developments in the endourology field have allowed full endoscopic access to upper tract tumours. Endoscopic resection or ablation of the tumour can be undertaken safely and effectively through ureteroscopy or percutaneous nephroscopy with low risk of extra-renal tumour seeding. For superficial (Ta, T1), low grade (I, II) tumours, a conservative approach can be selected without compromising survival and prognosis. For muscle invasive > T2 or high grade (III) tumours, nephroureterectomy remains the treatment of choice. Intracavitary BCG used after percutaneous resection reduces the risk of recurrence of upper tract urothelial tumours regardless of the grade. Finally, the world literature and our personal experience have shown that the tumour grade and stage are the two independent factors that affect survival of patients with upper urinary tract tumours.

上尿路尿路上皮肿瘤的组织学表现和临床表现与膀胱肿瘤几乎相同。浅表乳头状肿瘤虽然复发频率高,但很少进展并转变为侵袭性疾病。在泌尿系统领域的技术发展已经允许充分的内窥镜进入上尿道肿瘤。通过输尿管镜或经皮肾镜可以安全有效地进行肿瘤的内镜切除或消融,肾外肿瘤播散的风险低。对于浅表(Ta, T1),低级别(I, II)肿瘤,可以选择保守入路,而不影响生存和预后。对于肌肉侵入性;T2或高级别(III)肿瘤,肾输尿管切除术仍然是治疗的选择。经皮切除后使用腔内卡介苗可降低上尿路上皮肿瘤复发的风险,无论其级别如何。最后,世界文献和我们的个人经验表明,肿瘤分级和分期是影响上尿路肿瘤患者生存的两个独立因素。
{"title":"Traitement conservateur des tumeurs des voies excrétrices supérieures","authors":"M.-E. Jabbour ,&nbsp;A.-D. Smith","doi":"10.1016/j.anuro.2006.10.003","DOIUrl":"10.1016/j.anuro.2006.10.003","url":null,"abstract":"<div><p>The histological appearance and the clinical behaviour of upper urinary tract urothelial tumours are almost identical to those of the bladder. Superficial papillary tumours rarely progress and turn to invasive disease despite a high frequency of recurrence. Technical developments in the endourology field have allowed full endoscopic access to upper tract tumours. Endoscopic resection or ablation of the tumour can be undertaken safely and effectively through ureteroscopy or percutaneous nephroscopy with low risk of extra-renal tumour seeding. For superficial (Ta, T1), low grade (I, II) tumours, a conservative approach can be selected without compromising survival and prognosis. For muscle invasive &gt; T2 or high grade (III) tumours, nephroureterectomy remains the treatment of choice. Intracavitary BCG used after percutaneous resection reduces the risk of recurrence of upper tract urothelial tumours regardless of the grade. Finally, the world literature and our personal experience have shown that the tumour grade and stage are the two independent factors that affect survival of patients with upper urinary tract tumours.</p></div>","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.anuro.2006.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26584853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hormone-refractory prostate cancer]. [激素难治性前列腺癌]。
Pub Date : 2007-01-01 DOI: 10.1007/978-3-662-46875-3_2813
I. Alexandre, O. Rixe
{"title":"[Hormone-refractory prostate cancer].","authors":"I. Alexandre, O. Rixe","doi":"10.1007/978-3-662-46875-3_2813","DOIUrl":"https://doi.org/10.1007/978-3-662-46875-3_2813","url":null,"abstract":"","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51371714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annales D Urologie
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