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[Epidemiologic survey of acute poisoning in the south area of the Community of Madrid: the VEIA 2004 study]. [马德里共同体南部地区急性中毒流行病学调查:VEIA 2004研究]。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600003
P J Caballero Vallés, S Dorado Pombo, A Díaz Brasero, M E García Gil, L Yubero Salgado, N Torres Pacho, C Ibero Esparza, J Cantero Bengoechea

Objective: VEIA study is an evolutional registry of acute poisonings (AP) attended in the Emergency Room of the Doce de Octubre Hospital in Madrid (Spain) in a whole year (1979, 1985, 1990, 1994,1997 and 2000). We present the 2004 study and compare the results with the previous years.

Methods and results: Methodology has been identical across VEIA STUDY. Of 1508 AP, 610 are suicide attempts (IAVIS), 319 ethylic, (IAVE), and 218 by illicit drugs (IAVD). Of the 2,259 toxics involved, 48% are medications (50% benzodiacepines) alcohol 25% and illicit drugs 13%.

Conclusions: There is an important increase (34%) of cases and the incidence surpasses all published in our country. There are no gender differences nor in the whole neither the Health Area Census, but there are differences in IAVIS, IAVE and IAVD. IAVIS increase in 35%. Benzodiacepines poisoning increases two-fold as well as antidepressive drugs do in women. In men also increase, but in a minor extent. Acetaminophen remains the same in 23%. NSAID's, adjuvants and myorelaxants increase in women as do also alcohol and other poisons that almost equal men's. There are 13 cases of IAVIS in patients with alimentary disorders. Among men, a quarter are illicit drug abusers. In IAVE, the group without alcoholism grows and the total decreases. Illicit drugs duplicate the number of the former year. Cocaine supposes already 2/3 of the cases, MDMA ascends to 22 cases and they appear new substances as glue, without doubt as an effect of immigration and ketamine. Finally 205 household accidents and 57 industrial injuries complete the series.

目的:对西班牙马德里十月医院(Doce de Octubre Hospital)急诊室一年内(1979、1985、1990、1994、1997和2000年)急性中毒(AP)的演变登记进行VEIA研究。本文介绍了2004年的研究结果,并将其与前几年的结果进行了比较。方法和结果:VEIA研究的方法是相同的。在1508个AP中,有610个是自杀未遂(IAVIS), 319个是酗酒(IAVE), 218个是吸毒(IAVD)。在涉及的2259种有毒物质中,48%是药物(50%是苯二氮卓类药物),25%是酒精,13%是非法药物。结论:病例数显著增加(34%),发生率超过我国已发表的病例数。无论是在总体上还是在卫生地区普查中,都没有性别差异,但在家庭综合医疗保险、家庭综合医疗保险和家庭综合医疗保险方面存在差异。IAVIS增加了35%。在女性中,苯二氮卓类药物和抗抑郁药物的中毒增加了两倍。在男性中也有增加,但幅度不大。对乙酰氨基酚在23%中保持不变。非甾体抗炎药、佐剂和肌肉松弛剂在女性体内的含量增加,酒精和其他毒物的含量几乎与男性相同。消化道疾病患者中有13例IAVIS。在男性中,四分之一是非法药物滥用者。在IAVE中,没有酗酒的群体增加,总数减少。非法药品的数量与前一年相同。可卡因已经占了三分之二,摇头丸上升到22例,它们出现了新的物质,如胶水,毫无疑问是移民和氯胺酮的影响。最后,205起家庭事故和57起工伤事故完成了这个系列。
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引用次数: 14
[Perioperatory artificial nutrition]. 【围手术期人工营养】。
Pub Date : 2008-06-01
D A de Luis, R Aller, O Izaola

Malnutrition increases post surgical morbimortality, hospital stance and economical costs. Possibilities of nutritional intervention in surgical patients are important. Early enteral nutrition is better than total parenteral nutrition in patients under surgery. Periroperaoty nutritional support must be administrated to patients with severe or middle undernutrition and will be under surgery, during 7-14 days before surgical intervention, if this intervention could be delayed. Total parenteral nutrition will be not used regularly in patients under mayor digestive surgical procedures. Inmunonutrition has been demonstrated useful in surgical patients. Evidence demonstrates that inmunotritional formulas decrease incidence of infections, hospital stance and time of ventilation in patients in UCI wards. New research areas have been explored in this topic area, carbohydrate utility in presurgical patients and probiotic in enteral formulas.

营养不良增加手术后死亡率、住院情况和经济成本。外科病人营养干预的可能性是很重要的。手术患者早期肠内营养优于全肠外营养。对于严重或中度营养不良且将处于手术状态的患者,在手术干预前7-14天必须给予围手术期营养支持,如果干预可以延迟的话。全肠外营养将不定期用于主要消化外科手术的患者。免疫营养已被证明对外科病人有用。有证据表明,免疫配方降低感染的发生率,医院的立场和通气时间在UCI病房的病人。在这一主题领域,碳水化合物在术前患者中的应用和益生菌在肠内配方中的应用已被探索。
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引用次数: 0
[Muscle weakness as first manifestation of panhypopituitarism secondary to empty sella syndrome]. [肌肉无力是空蝶鞍综合征继发的垂体功能减退症的首要表现]。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600016
C Paz Flores, J Rosales Carballa, J Blanco Loberías
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引用次数: 1
[Acute renal failure in a young male with cellulitis in the lower leg]. 【年轻男性下肢蜂窝织炎急性肾衰竭一例】。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600009
A Rodríguez Lorenzo, F Martelo Villar

Necrotizing fascitiis due to Streptococcus Pyogenes has a high mortality rate. Detection of the infection before it developes to the streptococcal toxic shock syndrome is quite challenging and its one of the main goals of its management because at this final stage the treatment is in most of the cases ineffective. In a secuence of events of the progression of the infection to shock, renal failure occurs before hipotension very often. We report the case of a 38-year-old patient affected by a fulminant necrotizing fascitiis by Streptococcus Pyogenes which presented at admission with lower leg cellulitis and acute renal failure.

化脓性链球菌引起的坏死性筋膜炎死亡率高。在感染发展为链球菌中毒性休克综合征之前进行检测是非常具有挑战性的,也是其管理的主要目标之一,因为在最后阶段,大多数病例的治疗无效。在感染发展到休克的一系列事件中,肾衰竭通常发生在高血压之前。我们报告的情况下,38岁的病人影响暴发性坏死性筋膜炎化脓性链球菌在入院时表现为下肢蜂窝组织炎和急性肾功能衰竭。
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引用次数: 2
[Autoimmunity from the medicine based on Virchow's postulates to the medicine based on the postulates of the molecular biology and molecular epidemiology]. [从基于魏尔肖原理的药物到基于分子生物学和分子流行病学原理的药物]。
Pub Date : 2008-06-01
F Blasco Patiño
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引用次数: 0
[Epidemiological events related to decompensated heart failure]. [与失代偿性心力衰竭相关的流行病学事件]。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600002
A Hermida Ameijeiras, M Pazo Núñez, R de la Fuente Cid, F L Lado Lado, L Hernández Fernández, I Rodríguez López

Objective: The present study aimed to evaluate the profile of patients with decompensated heart failure hospitalized in a tertiary hospital.

Methods: It was designed an observational and retrospective study where data from clinical records of patients suffering from heart failure along 2005 were registered randomly.

Results: 209 patients were collected (average age: 78.6 +/- 9.1; male: 52.4%) with a comorbidity rate of 87.55%. Almost one third of them have not stimation of systolic function and among the others 72.4% have it preserved. Most of decompensated were due to respiratory infections. Ischemic-hipertensive cardiopathy was the most frequent aetiology of systolic disfunction. Average stay was 12.9 days with a mortality rate of 9.56%. Its main risk factors were advanced stages in NYHA od Red Cross scales, as so as dementia or ictus.

Conclusions: The present study shows a patient hospitalized for decompensated heart failure roughly different from that one reported at clinical trials. It makes difficult to apply therapeutical interventions, previously well documented to be useful.

目的:了解某三级医院失代偿性心力衰竭患者的特点。方法:采用观察性和回顾性研究,随机选取2005年以来心力衰竭患者的临床资料。结果:共收集患者209例,平均年龄78.6±9.1岁;男性:52.4%),合并率87.55%。其中近三分之一的人没有收缩功能的估计,其中72.4%的人保留了收缩功能。大多数失代偿是由于呼吸道感染。缺血性高血压性心脏病是收缩功能障碍最常见的病因。平均住院时间12.9 d,死亡率9.56%。其主要危险因素是NYHA od红十字量表的晚期,以及痴呆或暴走。结论:本研究显示失代偿性心力衰竭住院患者与临床试验报道的患者大致不同。这使得治疗性干预措施难以应用,而这些干预措施以前已被充分证明是有用的。
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引用次数: 17
[Pneumocephalus after cocaine inhalation]. [可卡因吸入后的脑气]。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600013
I F Aomar Millán, I Aguilar Cruz, L Pérez Fernández, L López Pérez, J Pozo
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引用次数: 1
[Optic neuromyelitis. Main differences with multiple sclerosis]. (视neuromyelitis。与多发性硬化症的主要区别]。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600010
I Lopategui Cabezas, M Cervantes Llano, G Pentón Rol

The optic neuromyelitis or syndrome of Devic is an inflammatory and autoimmune illness of the central nervous system. It is characterized by attacks of optic neuritis and myelitis, being able to produce blindness, great neurological disability and even the short term death. Until the moment an effective treatment doesn't exist, the therapy is centred in the treatment of the acute attacks, the medical prevention of the complications and the rehabilitation. This article is a revision of this not very common illness, considering that its prevalence in our country has gone in increase. We compare between the optic neuromyelitis and the multiple sclerosis, being based on the main ones characteristic clinical-epidemic that distinguishes these two pathologies, considered by many clinical variants of oneself illness.

视神经脊髓炎是一种中枢神经系统的炎症性和自身免疫性疾病。其特点是视神经炎和脊髓炎发作,可导致失明、严重的神经残疾,甚至短期死亡。在没有有效的治疗方法之前,治疗的重点是急性发作的治疗、并发症的医学预防和康复。这篇文章是对这种不太常见的疾病的修订,考虑到它在我国的患病率已经上升。我们比较视神经脊髓炎和多发性硬化症,是基于主要特征的临床流行病学,以区分这两种病理,考虑到许多临床变体自己的疾病。
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引用次数: 7
[Hospitalizations due to decompensated cardiac insufficiency in Spain]. [西班牙因失代偿性心功能不全而住院]。
Pub Date : 2008-06-01
C Macaya Miguel, R Bover Freire
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引用次数: 0
[Suppurative thrombophlebitis central venous catheterization]. 化脓性血栓性静脉炎中心静脉置管术。
Pub Date : 2008-06-01 DOI: 10.4321/s0212-71992008000600007
A Ramos Martínez, I Sánchez Romero, P A Saura Lorente, A Parajón Díaz

Suppurative thrombophlebitisis a very infrequent complication of the central venous catheterization. The majority of the cases are produced by species of staphylococci. A 22-year-old colombian-woman, student, without toxic habits was admitted because of temporary left astrocytoma (grade II). Nine days after implementing a catheter in the right subclavian vein she presented high fever (39.5 degrees C), shivers, progressive right side neck swelling and odinofagia. She had leukocytosis (26,300 cells/microl) and normal cerebrospinal fluid. After withdrawing the catheter, Staphylococcus aureus was isolated in the tip of the catheter and in four bottles of blood cultures. A neck CT demonstrated expansion and absence of contrast in the right internal jugular vein. The patient evolved satisfactorily with cloxacillin, gentamycin and low molecular weight heparin.

化脓性血栓性静脉炎是中心静脉置管术中一种罕见的并发症。大多数病例是由葡萄球菌引起的。一名22岁的哥伦比亚女学生,无不良习惯,因暂时性左侧星形细胞瘤(II级)入院。在右侧锁骨下静脉植入导管9天后,她出现高烧(39.5℃)、寒颤、进行性右侧颈部肿胀和腺癌。她有白细胞增多(26,300个细胞/微升),脑脊液正常。拔管后,在导管尖端和4瓶血培养液中分离金黄色葡萄球菌。颈部CT显示右侧颈内静脉扩张且无造影剂。患者经氯西林、庆大霉素和低分子肝素治疗进展满意。
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Anales De Medicina Interna
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