Pub Date : 2023-11-30DOI: 10.17816/clinpract456429
Daria A. Bolshakova, A. A. Kardanov, M. Maysigov, Alexander A. Akhpashev, D. O. Ilʼin, Andrey V. Korolev
Abstract. Interdigital neuroma is one of the most common diseases in foot surgery. At the same time, the diagnosis of neuroma can be a difficult task for orthopedic surgeon. The main purpose of this study is to evaluate the importance of collecting anamnesis and complaints, clinical tests and MRI of the foot in the diagnosis Interdigital neuromas. Materials and methods: The study presents a retrospective analysis of the medical histories and outpatient records of 28 patients (8 men and 20 women) treated at EMC ECSTO in the period from 2017 to 2022. The examination was performed according to a standardized protocol: collection of complaints and anamnesis, palpation, manual testing, including Mulder's click test. As part of the examination, all patients did MRI of the foot. The average age at the time of surgical treatment was 45 years. Resection of a part of the affected nerve with subsequent histological examination was considered the "gold standard" in the treatment and verification of interdigital neuromas. Results: The sensitivity of MRI in the diagnosis of interdigital neuromas was 86%, the sensitivity of the Mulder test was 61%. Pain during palpation of the affected interdigital space was determined in 100% of cases. Conclusion: the combination of manual examination and MRI imaging, analysis of complaints and anamnesis makes it possible to diagnose Morton's neuroma in most cases.
{"title":"Instrumental and clinical diagnosis of interdigital neuroma","authors":"Daria A. Bolshakova, A. A. Kardanov, M. Maysigov, Alexander A. Akhpashev, D. O. Ilʼin, Andrey V. Korolev","doi":"10.17816/clinpract456429","DOIUrl":"https://doi.org/10.17816/clinpract456429","url":null,"abstract":"Abstract. Interdigital neuroma is one of the most common diseases in foot surgery. At the same time, the diagnosis of neuroma can be a difficult task for orthopedic surgeon. The main purpose of this study is to evaluate the importance of collecting anamnesis and complaints, clinical tests and MRI of the foot in the diagnosis Interdigital neuromas. Materials and methods: The study presents a retrospective analysis of the medical histories and outpatient records of 28 patients (8 men and 20 women) treated at EMC ECSTO in the period from 2017 to 2022. The examination was performed according to a standardized protocol: collection of complaints and anamnesis, palpation, manual testing, including Mulder's click test. As part of the examination, all patients did MRI of the foot. The average age at the time of surgical treatment was 45 years. Resection of a part of the affected nerve with subsequent histological examination was considered the \"gold standard\" in the treatment and verification of interdigital neuromas. Results: The sensitivity of MRI in the diagnosis of interdigital neuromas was 86%, the sensitivity of the Mulder test was 61%. Pain during palpation of the affected interdigital space was determined in 100% of cases. Conclusion: the combination of manual examination and MRI imaging, analysis of complaints and anamnesis makes it possible to diagnose Morton's neuroma in most cases.","PeriodicalId":508133,"journal":{"name":"Journal of Clinical Practice","volume":"339 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139202805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-30DOI: 10.17816/clinpract567924
Anton K. Peresada, D. Dundua, A. Kedrova, Irina N. Oleinikova, Anna V. Masterkova
Background: Cancer patients receiving high doses of cardiotoxic combined anticancer drugs have an increased risk of cardiovascular complications. During treatment, patients may experience complications from the cardiovascular system, in particular chronic heart failure (CHF). Without the necessary laboratory and instrumental control, it is impossible to predict in advance the development of heart failure, which often complicates chemotherapy, and, in some cases necessitates cancellation of life-saving anticancer therapy. It turned out that timely cardioprotection, a drug intervention aimed at preventing myocardial dysfunction in cancer patients, can prevent the development of heart failure. Aim: The purpose of this review is to briefly reflect the mechanisms of cardiotoxicity in various chemotherapy regimens, as well as the current possibilities of cardioprotection in cancer patients receiving cardiotoxic chemotherapy
{"title":"A modern view on cardioprotective therapy in cancer patients receiving cardiotoxic chemotherapy","authors":"Anton K. Peresada, D. Dundua, A. Kedrova, Irina N. Oleinikova, Anna V. Masterkova","doi":"10.17816/clinpract567924","DOIUrl":"https://doi.org/10.17816/clinpract567924","url":null,"abstract":"Background: Cancer patients receiving high doses of cardiotoxic combined anticancer drugs have an increased risk of cardiovascular complications. During treatment, patients may experience complications from the cardiovascular system, in particular chronic heart failure (CHF). Without the necessary laboratory and instrumental control, it is impossible to predict in advance the development of heart failure, which often complicates chemotherapy, and, in some cases necessitates cancellation of life-saving anticancer therapy. It turned out that timely cardioprotection, a drug intervention aimed at preventing myocardial dysfunction in cancer patients, can prevent the development of heart failure. Aim: The purpose of this review is to briefly reflect the mechanisms of cardiotoxicity in various chemotherapy regimens, as well as the current possibilities of cardioprotection in cancer patients receiving cardiotoxic chemotherapy","PeriodicalId":508133,"journal":{"name":"Journal of Clinical Practice","volume":"2 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139200281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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