首页 > 最新文献

Journal of the Association of Physicians of India最新文献

英文 中文
Quiz in Emergency Medicine 急诊医学小测验
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0007
{"title":"Quiz in Emergency Medicine","authors":"","doi":"10.5005/njem-11015-0007","DOIUrl":"https://doi.org/10.5005/njem-11015-0007","url":null,"abstract":"","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic Dissection Presenting as Acute Ischaemic Stroke and Thrombolysed: A Case Series 主动脉夹层表现为急性缺血性中风并被溶栓:一个病例系列
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0010
Ankur Verma, Sanjay Jaiswal, Amit Batra, Abbas A Khatai, Nilesh Prasad, Saumya Khard, Shivani Sarda
Acute aortic dissection (AAD) masquerading as ischaemic stroke can be a challenging diagnosis for clinicians and can pose complications for the patient. Type A dissections extending into the vessels of the brain and neck can cause cerebral hypoperfusion leading to strokes or stroke-like symptoms. Thrombolysis of ischaemic strokes caused due to aortic dissection can be catastrophic for the patient. We present a series of two cases of aortic dissection presenting as strokes which were thrombolysed and underwent surgical intervention for dissection but did not suffer catastrophic complications. We do not recommend to rule out dissection in acute stroke patients before thrombolysis.
伪装成缺血性中风的急性主动脉夹层(AAD)对临床医生来说是一个具有挑战性的诊断,并可能给患者带来并发症。延伸至脑部和颈部血管的 A 型夹层可引起脑灌注不足,导致中风或类似中风的症状。主动脉夹层导致的缺血性中风的溶栓治疗对患者来说可能是灾难性的。我们介绍了两例以中风为表现的主动脉夹层病例,这两例患者均接受了溶栓治疗,并因主动脉夹层接受了手术干预,但没有出现灾难性并发症。我们不建议急性中风患者在溶栓前排除夹层。
{"title":"Aortic Dissection Presenting as Acute Ischaemic Stroke and Thrombolysed: A Case Series","authors":"Ankur Verma, Sanjay Jaiswal, Amit Batra, Abbas A Khatai, Nilesh Prasad, Saumya Khard, Shivani Sarda","doi":"10.5005/njem-11015-0010","DOIUrl":"https://doi.org/10.5005/njem-11015-0010","url":null,"abstract":"Acute aortic dissection (AAD) masquerading as ischaemic stroke can be a challenging diagnosis for clinicians and can pose complications for the patient. Type A dissections extending into the vessels of the brain and neck can cause cerebral hypoperfusion leading to strokes or stroke-like symptoms. Thrombolysis of ischaemic strokes caused due to aortic dissection can be catastrophic for the patient. We present a series of two cases of aortic dissection presenting as strokes which were thrombolysed and underwent surgical intervention for dissection but did not suffer catastrophic complications. We do not recommend to rule out dissection in acute stroke patients before thrombolysis.","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency Medicine Academics in India: A Roadmap for Future 印度的急诊医学学术界:未来路线图
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0008
S. Ts
{"title":"Emergency Medicine Academics in India: A Roadmap for Future","authors":"S. Ts","doi":"10.5005/njem-11015-0008","DOIUrl":"https://doi.org/10.5005/njem-11015-0008","url":null,"abstract":"","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What May Stand Behind Chest Pain: A Case Report on Aortic Dissection 胸痛背后的原因:主动脉夹层病例报告
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0004
Aishwarya A, Nilu Sunil
Aortic dissection (AD) is a relatively uncommon, rare disorder and potentially misdiagnosed disease. Early diagnosis and treatment is required for the patient's survival. Aortic dissection can be fatal if misdiagnosed. A 50-year-old adult male presented to emergency with acute chest pain and having a medical history of aortic stenosis post-aortic valve replacement 9 months back and a family history of ischaemic heart disease. Pain was relieved by analgesics. After further investigations by echocardiography and CT Angiography, it was diagnosed as AD Standford type A and DeBakey type 1, in view of the critical nature of illness, patient attenders wanted only medical management. The patient was declared dead after 2 days of diagnosis.
主动脉夹层(AD)是一种相对不常见的罕见疾病,也是一种可能被误诊的疾病。为了患者的生存,必须及早诊断和治疗。如果被误诊,主动脉夹层可能会致命。一名 50 岁的成年男性因急性胸痛急诊就诊,病史为主动脉瓣置换术后主动脉瓣狭窄 9 个月,家族史为缺血性心脏病。止痛药缓解了疼痛。经过超声心动图和 CT 血管造影的进一步检查,诊断为 AD Standford A 型和 DeBakey 1 型,鉴于病情危重,病人的主治医生只希望进行药物治疗。患者在确诊两天后宣告死亡。
{"title":"What May Stand Behind Chest Pain: A Case Report on Aortic Dissection","authors":"Aishwarya A, Nilu Sunil","doi":"10.5005/njem-11015-0004","DOIUrl":"https://doi.org/10.5005/njem-11015-0004","url":null,"abstract":"Aortic dissection (AD) is a relatively uncommon, rare disorder and potentially misdiagnosed disease. Early diagnosis and treatment is required for the patient's survival. Aortic dissection can be fatal if misdiagnosed. A 50-year-old adult male presented to emergency with acute chest pain and having a medical history of aortic stenosis post-aortic valve replacement 9 months back and a family history of ischaemic heart disease. Pain was relieved by analgesics. After further investigations by echocardiography and CT Angiography, it was diagnosed as AD Standford type A and DeBakey type 1, in view of the critical nature of illness, patient attenders wanted only medical management. The patient was declared dead after 2 days of diagnosis.","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Teaching and Demonstration in Improvement of Knowledge and Skill on CPR among School-going Adolescents: A Quasi-experimental Study 教学和示范对提高在校青少年心肺复苏知识和技能的效果:准实验研究
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0009
Rajadurai Meenakshisundaram, Anand Raj Ramavel, Nayyara Banu, Akmal Areeb, Esther Monica Jared Premkumar, Salman Saeed
Background: Cardiopulmonary resuscitation (CPR) is one of the most evolving areas of saving actions that improve the survival rates following cardiac arrest and educating high school students can play a dynamic role in case of emergencies in society. Education of school students in CPR is a strategic goal for the improvement of bystander CPR in rural society. If adolescents were trained to perform CPR during school physical education hours, this may be a cost-effective approach to CPR training. This study is conducted to assess the effectiveness of health education in the improvement of knowledge of CPR among school-going adolescents. Aim: To assess the effect of a training program on students’ knowledge of CPR. Objective: (A) To determine the background knowledge of high school students about cardiac arrest and basic life support in adult victims of cardiac arrest. (B) To determine the association between knowledge of cardiopulmonary resuscitation and skills with selected demographic variables. Materials and methods: This is a quasi-experimental study conducted among adolescents aged 13–15 years attending schools in rural areas of South India. The study was conducted between Jan 2022 and Jan 2023. 680 students were included in this study. The universal sampling method was used to enumerate the participants to reduce the impact of the dropout rate. The data was collected using a pre-tested semi-structured questionnaire by interview method. Basic teaching of CPR for the participants included 2 hours of oral teaching using lecture method, question and answer discussion method as well as 2 hours of practical session using demonstration, practice on a manikin, provision of feedback and correction of errors. Results: A total of 680 participants were grouped into three categories according to their knowledge scores: (A) fair, (B) Moderate, and (C) Good scores obtained in pre-training observation and post-training observation. Initially, there were 666 (97.9%) in the fair category, most of them improved after training as seen in the post-training observation results, with 97 (14.3%) persons in the fair (A) category. There was not a single student in the good category of the score before intervention, which increased to 665 (45.6%) in the good category of knowledge. The mean score of pre-training is 2.55, and the post-training score is significantly increased to 9.5. Conclusion: An improvement is observed in knowledge of CPR post-training with planned teaching and demonstration. Hence, this method can be considered a logical solution for improving knowledge about CPR in cases of emergency life-saving skills in a particular group of society.
背景:心肺复苏术(CPR)是提高心脏骤停后存活率的救治行动中发展最快的领域之一,对中学生进行心肺复苏术教育可在社会突发事件中发挥积极作用。对在校学生进行心肺复苏术教育是改善农村社会旁观者心肺复苏术的一个战略目标。如果在学校体育课时间对青少年进行心肺复苏培训,这可能是一种经济有效的心肺复苏培训方法。本研究旨在评估健康教育在提高在校青少年心肺复苏知识方面的效果。目的:评估培训计划对学生心肺复苏知识的影响。目标:(A)确定高中生对心脏骤停和成人心脏骤停患者基本生命支持的背景知识。(B) 确定心肺复苏知识和技能与选定人口统计学变量之间的关联。材料和方法:这是一项在印度南部农村地区学校就读的 13-15 岁青少年中开展的准实验研究。研究时间为 2022 年 1 月至 2023 年 1 月。共有 680 名学生参与研究。研究采用普遍抽样法对参与者进行统计,以减少辍学率的影响。数据收集采用了预先测试的半结构式问卷,以访谈的方式进行。对学员进行的心肺复苏术基础教学包括 2 个小时的口头教学(采用讲授法、问答讨论法)以及 2 个小时的实践课程(采用演示法、在人体模型上练习、提供反馈和纠正错误)。结果:根据学员在培训前观察和培训后观察中获得的知识得分,共将 680 名学员分为三类:(A) 一般、(B) 中等和(C) 良好。最初有 666 人(97.9%)属于一般,从培训后的观察结果来看,其中大部分人在培训后都有所改善,有 97 人(14.3%)属于一般(A)类。在干预前,没有一个学生的知识得分在良好类别,而在干预后,知识得分在良好类别的学生增加到 665 人(45.6%)。培训前的平均得分为 2.55 分,培训后的得分大幅提高至 9.5 分。结论通过有计划的教学和示范,可以观察到心肺复苏术知识在培训后有所提高。因此,这种方法可被视为提高特定社会群体对紧急救生技能的心肺复苏知识的合理解决方案。
{"title":"Effectiveness of Teaching and Demonstration in Improvement of Knowledge and Skill on CPR among School-going Adolescents: A Quasi-experimental Study","authors":"Rajadurai Meenakshisundaram, Anand Raj Ramavel, Nayyara Banu, Akmal Areeb, Esther Monica Jared Premkumar, Salman Saeed","doi":"10.5005/njem-11015-0009","DOIUrl":"https://doi.org/10.5005/njem-11015-0009","url":null,"abstract":"Background: Cardiopulmonary resuscitation (CPR) is one of the most evolving areas of saving actions that improve the survival rates following cardiac arrest and educating high school students can play a dynamic role in case of emergencies in society. Education of school students in CPR is a strategic goal for the improvement of bystander CPR in rural society. If adolescents were trained to perform CPR during school physical education hours, this may be a cost-effective approach to CPR training. This study is conducted to assess the effectiveness of health education in the improvement of knowledge of CPR among school-going adolescents. Aim: To assess the effect of a training program on students’ knowledge of CPR. Objective: (A) To determine the background knowledge of high school students about cardiac arrest and basic life support in adult victims of cardiac arrest. (B) To determine the association between knowledge of cardiopulmonary resuscitation and skills with selected demographic variables. Materials and methods: This is a quasi-experimental study conducted among adolescents aged 13–15 years attending schools in rural areas of South India. The study was conducted between Jan 2022 and Jan 2023. 680 students were included in this study. The universal sampling method was used to enumerate the participants to reduce the impact of the dropout rate. The data was collected using a pre-tested semi-structured questionnaire by interview method. Basic teaching of CPR for the participants included 2 hours of oral teaching using lecture method, question and answer discussion method as well as 2 hours of practical session using demonstration, practice on a manikin, provision of feedback and correction of errors. Results: A total of 680 participants were grouped into three categories according to their knowledge scores: (A) fair, (B) Moderate, and (C) Good scores obtained in pre-training observation and post-training observation. Initially, there were 666 (97.9%) in the fair category, most of them improved after training as seen in the post-training observation results, with 97 (14.3%) persons in the fair (A) category. There was not a single student in the good category of the score before intervention, which increased to 665 (45.6%) in the good category of knowledge. The mean score of pre-training is 2.55, and the post-training score is significantly increased to 9.5. Conclusion: An improvement is observed in knowledge of CPR post-training with planned teaching and demonstration. Hence, this method can be considered a logical solution for improving knowledge about CPR in cases of emergency life-saving skills in a particular group of society.","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Crisis to Care: The Spectacular Evolution of Emergency Medicine in India 从危机到关怀:印度急诊医学的辉煌发展
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0005
Saravana Kumar
{"title":"From Crisis to Care: The Spectacular Evolution of Emergency Medicine in India","authors":"Saravana Kumar","doi":"10.5005/njem-11015-0005","DOIUrl":"https://doi.org/10.5005/njem-11015-0005","url":null,"abstract":"","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Blood Cultures of Patients Presenting to the Emergency Department in a Tertiary Healthcare Hospital in Mumbai 孟买一家三级医疗保健医院急诊科患者的血培养分析
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0006
Deepak Kishor Sharma, Sandeep B Gore
Aim and objectives: Analysis of blood cultures taken from patients attending emergency departments is an important exercise in determining the common pathogens prevalent in the region. The distribution of these infective pathogens keeps changing over time, and the rise in antimicrobial-resistant pathogens makes it difficult to routinely conduct effective empirical broad-spectrum antimicrobial therapy. This study aimed to analyse the results of blood cultures obtained from patients presenting to the Emergency Department of a Tertiary Healthcare Hospital in Mumbai and provide updated and detailed information on the distribution of causative pathogens in adult sepsis and study their antibiotic-susceptibility pattern. Materials and methods: A hospital-based prospective cross-sectional study of 121 positive blood culture reports was conducted at the Department of Emergency Medicine, Fortis Hospital Mulund, Mumbai, which included all adult (age > 18 yrs) suspected sepsis patients arriving to the Emergency Department whose blood cultures were sent from the Emergency Department from January 2021 to December 2021. Results: The study showed that mean age of the study cases was 59.3 years with 59.5% cases that belonged to the elderly age group with a male predominance (56.2% males–43.8% females). Overall, Gram-negative isolates were seen in 95% cases, while Gram-positive isolates were seen in only 1.7% cases. The most common organism isolated from cases with sepsis was Escherichia coli (45.5%) followed by Klebsiella (13.2%), Salmonella (10.7%), Stenotrophomonas (7.4%) and Pseudomonas (5%). Among Gram-positive organisms, Staphylococcus aureus was the most common organism isolated (1.7%). Escherichia coli isolates showed poor sensitivity towards fluoroquinolones and cephalosporins while good sensitivity towards aminoglycosides, carbapenems and combination drugs like Cefoperazone and Sulbactam and Piperacillin and Tazobactam. These findings suggest that Gram-negative organisms are the most common isolates observed in this study, with E. coli being the predominant pathogen followed by Klebsiella. High-level antimicrobial resistance was observed in sepsis cases for commonly used antimicrobials like fluoroquinolones and cephalosporins.
目的和目标:对急诊科就诊患者的血液培养物进行分析是确定该地区常见病原体的一项重要工作。随着时间的推移,这些感染性病原体的分布不断发生变化,耐抗菌素病原体的增加使得常规有效的经验性广谱抗菌疗法难以实施。本研究旨在分析孟买一家三级医疗保健医院急诊科患者的血液培养结果,提供成人败血症致病病原体分布的最新详细信息,并研究其抗生素敏感性模式。材料和方法:孟买 Fortis Mulund 医院急诊医学科对 121 份血培养阳性报告进行了医院前瞻性横断面研究,研究对象包括 2021 年 1 月至 2021 年 12 月期间急诊科送检的所有成人(年龄大于 18 岁)疑似败血症患者。研究结果研究显示,研究病例的平均年龄为 59.3 岁,59.5% 的病例属于老年组,男性占多数(56.2% 为男性,43.8% 为女性)。总体而言,95%的病例分离到革兰氏阴性菌,而革兰氏阳性菌仅占 1.7%。败血症病例中最常见的分离菌是大肠埃希菌(45.5%),其次是克雷伯菌(13.2%)、沙门氏菌(10.7%)、血吸虫(7.4%)和假单胞菌(5%)。在革兰氏阳性菌中,金黄色葡萄球菌是最常见的分离菌(1.7%)。分离出的大肠埃希菌对氟喹诺酮类和头孢菌素的敏感性较差,而对氨基糖苷类、碳青霉烯类和头孢哌酮与舒巴坦、哌拉西林与他唑巴坦等复方药物的敏感性较高。这些发现表明,革兰氏阴性菌是本研究中最常见的分离菌,其中大肠杆菌是最主要的病原体,其次是克雷伯氏菌。在败血症病例中,对氟喹诺酮类和头孢菌素类等常用抗菌药物产生了高度耐药性。
{"title":"Analysis of Blood Cultures of Patients Presenting to the Emergency Department in a Tertiary Healthcare Hospital in Mumbai","authors":"Deepak Kishor Sharma, Sandeep B Gore","doi":"10.5005/njem-11015-0006","DOIUrl":"https://doi.org/10.5005/njem-11015-0006","url":null,"abstract":"Aim and objectives: Analysis of blood cultures taken from patients attending emergency departments is an important exercise in determining the common pathogens prevalent in the region. The distribution of these infective pathogens keeps changing over time, and the rise in antimicrobial-resistant pathogens makes it difficult to routinely conduct effective empirical broad-spectrum antimicrobial therapy. This study aimed to analyse the results of blood cultures obtained from patients presenting to the Emergency Department of a Tertiary Healthcare Hospital in Mumbai and provide updated and detailed information on the distribution of causative pathogens in adult sepsis and study their antibiotic-susceptibility pattern. Materials and methods: A hospital-based prospective cross-sectional study of 121 positive blood culture reports was conducted at the Department of Emergency Medicine, Fortis Hospital Mulund, Mumbai, which included all adult (age > 18 yrs) suspected sepsis patients arriving to the Emergency Department whose blood cultures were sent from the Emergency Department from January 2021 to December 2021. Results: The study showed that mean age of the study cases was 59.3 years with 59.5% cases that belonged to the elderly age group with a male predominance (56.2% males–43.8% females). Overall, Gram-negative isolates were seen in 95% cases, while Gram-positive isolates were seen in only 1.7% cases. The most common organism isolated from cases with sepsis was Escherichia coli (45.5%) followed by Klebsiella (13.2%), Salmonella (10.7%), Stenotrophomonas (7.4%) and Pseudomonas (5%). Among Gram-positive organisms, Staphylococcus aureus was the most common organism isolated (1.7%). Escherichia coli isolates showed poor sensitivity towards fluoroquinolones and cephalosporins while good sensitivity towards aminoglycosides, carbapenems and combination drugs like Cefoperazone and Sulbactam and Piperacillin and Tazobactam. These findings suggest that Gram-negative organisms are the most common isolates observed in this study, with E. coli being the predominant pathogen followed by Klebsiella. High-level antimicrobial resistance was observed in sepsis cases for commonly used antimicrobials like fluoroquinolones and cephalosporins.","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anticoagulants Induced Ecchymosis 抗凝剂引起的瘀斑
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0003
Seetharaman Nagasubbu, Sai Surendar Mohan, Ramkumar Selvam
A case report of oral anticoagulant—acenocoumarol Induced Ecchymosis. Acenocoumarol is a coumarin derivative and vitamin K antagonist. Adverse effects like ecchymosis that is potentially fatal if not noticed with an altered coagulation profile. Initiation of safer anticoagulants for mid to long-term treatment under the supervision of coagulation profile.
口服抗凝剂--醋硝香豆素诱发瘀斑的病例报告。醋硝香豆素是一种香豆素衍生物和维生素 K 拮抗剂。其不良反应包括瘀斑,如果不注意凝血功能的改变,瘀斑有可能致命。在凝血功能检查的监督下,开始使用更安全的抗凝剂进行中长期治疗。
{"title":"Anticoagulants Induced Ecchymosis","authors":"Seetharaman Nagasubbu, Sai Surendar Mohan, Ramkumar Selvam","doi":"10.5005/njem-11015-0003","DOIUrl":"https://doi.org/10.5005/njem-11015-0003","url":null,"abstract":"A case report of oral anticoagulant—acenocoumarol Induced Ecchymosis. Acenocoumarol is a coumarin derivative and vitamin K antagonist. Adverse effects like ecchymosis that is potentially fatal if not noticed with an altered coagulation profile. Initiation of safer anticoagulants for mid to long-term treatment under the supervision of coagulation profile.","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Neurotoxic Paralysis with Confounding Hypokalaemia 伴有低钾血症的迟发性神经中毒性麻痹
Pub Date : 2023-12-05 DOI: 10.5005/njem-11015-0002
Utsav Anand Mani, Mukesh Kumar, Haider Abbas, Pranay Gupta
Snakebite is a major health issue in India and developing nations across the globe. Common krait bites are associated with delayed paralysis and locked-in syndrome. Locked-in syndrome has been documented among patients of snakebite. Our case is unique due to the confounding effect of hypokalaemia which may confuse the physician as hypokalaemic periodic paralysis (HPP), a rare genetic condition which can also be precipitated by a stressful event such as snakebite. To the best of our knowledge, we could not associate the presence of hypokalaemia in patients of neurotoxic snakebite. As krait bite are often not associated with the history of having witnessed, a snake due to its nocturnal habit and painless bite, such hypokalaemia should not lead the physician to misdiagnose this snakebite as severe HPP. We urge our fellow researchers to look out for similar findings in their patients. Key messages: Locked-in syndrome in snakebites can be due to the effect of the venom in blood onto the ventral pons. To the best of our knowledge, we could not associate the presence of hypokalaemia in patients of neurotoxic snakebite. We presume this hypokalaemia to be nutritional in origin. As krait bites are often not associated with the history of having witnessed, a snake due to its nocturnal habit and painless bite, such hypokalaemia should not lead the physician to misdiagnose this snakebite as severe HPP. Keywords: Case report, Hypokalaemia, Neurotoxic, Snake envenomation
蛇咬伤是印度和全球发展中国家的一个主要健康问题。常见的蛇咬伤与迟发性瘫痪和锁定综合征有关。在被蛇咬伤的患者中,有锁闭综合征的记录。我们的病例比较特殊,因为低钾血症的混杂效应可能会让医生误认为是低钾血症性周期性麻痹(HPP),这是一种罕见的遗传病,也可能由蛇咬伤等应激事件诱发。据我们所知,我们无法将神经毒性蛇咬伤患者出现低钾血症联系起来。由于蛇的夜间习性和无痛性,被蛇咬伤的患者通常没有目击蛇的历史,因此这种低钾血症不应该导致医生将蛇咬伤误诊为严重的 HPP。我们敦促研究人员在他们的患者中留意类似的发现。关键信息蛇咬伤锁定综合征可能是由于血液中的毒液对腹侧脑桥的影响。据我们所知,神经毒性蛇咬伤患者中不存在低钾血症。我们推测这种低钾血症是营养性的。由于蛇的夜间活动习性和无痛咬伤,被蛇咬伤的患者通常没有目击蛇的历史,因此这种低钾血症不应该导致医生将这种蛇咬伤误诊为严重的 HPP。关键词病例报告 低钾血症 神经毒性 蛇咬伤
{"title":"Delayed Neurotoxic Paralysis with Confounding Hypokalaemia","authors":"Utsav Anand Mani, Mukesh Kumar, Haider Abbas, Pranay Gupta","doi":"10.5005/njem-11015-0002","DOIUrl":"https://doi.org/10.5005/njem-11015-0002","url":null,"abstract":"Snakebite is a major health issue in India and developing nations across the globe. Common krait bites are associated with delayed paralysis and locked-in syndrome. Locked-in syndrome has been documented among patients of snakebite. Our case is unique due to the confounding effect of hypokalaemia which may confuse the physician as hypokalaemic periodic paralysis (HPP), a rare genetic condition which can also be precipitated by a stressful event such as snakebite. To the best of our knowledge, we could not associate the presence of hypokalaemia in patients of neurotoxic snakebite. As krait bite are often not associated with the history of having witnessed, a snake due to its nocturnal habit and painless bite, such hypokalaemia should not lead the physician to misdiagnose this snakebite as severe HPP. We urge our fellow researchers to look out for similar findings in their patients. Key messages: Locked-in syndrome in snakebites can be due to the effect of the venom in blood onto the ventral pons. To the best of our knowledge, we could not associate the presence of hypokalaemia in patients of neurotoxic snakebite. We presume this hypokalaemia to be nutritional in origin. As krait bites are often not associated with the history of having witnessed, a snake due to its nocturnal habit and painless bite, such hypokalaemia should not lead the physician to misdiagnose this snakebite as severe HPP. Keywords: Case report, Hypokalaemia, Neurotoxic, Snake envenomation","PeriodicalId":508269,"journal":{"name":"Journal of the Association of Physicians of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the Association of Physicians of India
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1