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Positive Emotions and Quality of Life among Malaysian Patients on Methadone Maintenance Therapy and Their Psychosocial Correlates 马来西亚美沙酮维持疗法患者的积极情绪和生活质量及其社会心理相关因素
Pub Date : 2024-07-24 DOI: 10.3390/psychiatryint5030025
N. S. Ganesh, Manveen Kaur, R. A. Abd Rashid, R. Parameswaran, A. Hashim, C. Moey, Noh Amit, C. Siau, Chong Guan Ng
The main objective of this study was to assess the positive emotions and the quality of life among patients on methadone maintenance therapy (MMT) as well as their associated factors. This is a cross-sectional survey study. Participants undergoing MMT in two major Malaysian hospitals responded to the sociodemographic and clinical information sheet, the Positive Emotion Rating Scale (PERS), and the World Health Organization Quality of Life (WHOQOL)-BREF. Most of the participants (N = 154; mean age = 43.8 ± 9.0 years) were male (97.4%) and Malays (75.3%). Slightly more than half (50.6%) scored above 30 on the Positive Emotion Rating Scale. There was a significant association between being ethnically Malay, married, and employed and positive emotions. After adjusting for potential confounding factors, having positive emotions predicted a better overall, physical, and psychological quality of life. Being non-diabetic also significantly predicted a better quality of life in the overall domain, whilst not being married and family history of mental illness significantly predicted a lower overall and psychological quality of life. Positive emotions significantly improve patients’ quality of life in the MMT program, suggesting the inclusion of positive emotions in a holistic treatment approach.
本研究的主要目的是评估美沙酮维持疗法(MMT)患者的积极情绪和生活质量及其相关因素。这是一项横断面调查研究。在马来西亚两家主要医院接受美沙酮维持治疗的参与者对社会人口学和临床信息表、积极情绪评分量表(PERS)和世界卫生组织生活质量(WHOQOL)-BREF进行了回答。大多数参与者(N = 154;平均年龄 = 43.8 ± 9.0 岁)为男性(97.4%)和马来人(75.3%)。略多于一半的参与者(50.6%)在积极情绪评分量表中得分超过 30 分。马来裔、已婚、有工作与积极情绪之间有明显的关联。在对潜在的混杂因素进行调整后,积极情绪预示着更好的整体、生理和心理生活质量。非糖尿病患者也会显著提高整体生活质量,而未婚和有精神病家族史的人则会显著降低整体和心理生活质量。积极情绪能明显改善 MMT 项目中患者的生活质量,这表明积极情绪也是一种整体治疗方法的组成部分。
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引用次数: 0
Presence of Emotions in Network Discourse on Mental Health: Thematic Analysis 情感在心理健康网络话语中的存在:主题分析
Pub Date : 2024-07-09 DOI: 10.3390/psychiatryint5030024
Alba González Moreno, M. M. M. Molero Jurado
Mental health and emotions are two fundamental aspects of our overall well-being. Good mental health can help us manage and regulate our emotions in a healthy way. Similarly, emotions can affect our mental health if we are not able to recognize, express, and manage our emotions in a healthy way. The present research aims to conduct a thematic analysis on the presence of emotions in X (formerly known as Twitter) discourse on mental health. A total of 455 tweets dealing with mental health have been collected in this study. The results show that the presence of emotions in mental health discourse is quite limited compared to the non-use of emotions. Regarding those who do use emotions, love and anxiety stand out. When users do not address emotions, they do argue certain variables such as stress, depression, suicide, or job insecurity. It is argued that emotions do not receive the attention and importance they deserve in the field of mental health. If emotions are not properly recognized, understood, or managed, there may be several risks for society in general. Therefore, the need to promote emotional education with the intention of increasing people’s well-being and mental health is raised.
心理健康和情绪是我们整体健康的两个基本方面。良好的心理健康可以帮助我们以健康的方式管理和调节情绪。同样,如果我们不能以健康的方式认识、表达和管理自己的情绪,情绪也会影响我们的心理健康。本研究旨在对 X(前身为 Twitter)上有关心理健康的言论中存在的情绪进行主题分析。本研究共收集了 455 条涉及心理健康的推文。结果表明,与不使用情感的情况相比,情感在心理健康话语中的存在相当有限。在使用情感的推文中,爱和焦虑尤为突出。当使用者不使用情感时,他们会讨论某些变量,如压力、抑郁、自杀或工作不稳定。有人认为,情绪在心理健康领域没有得到应有的关注和重视。如果不能正确认识、理解或管理情绪,可能会给整个社会带来若干风险。因此,有必要促进情感教育,以提高人们的幸福感和心理健康水平。
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引用次数: 0
Revealing the Mechanisms That Contribute to Anger Expression Proneness in Patients with Brain Damage: The Importance of Executive Dysfunctions and Alexithymia 揭示脑损伤患者易产生愤怒情绪的机制:执行功能障碍和亚历山大症的重要性
Pub Date : 2024-07-03 DOI: 10.3390/psychiatryint5030023
Á. Romero-Martínez, C. Sarrate-Costa, Gabriel García-Pardo Sánchez-Barba, Lorena Vallejo Ortega, Sara López-Santamaría, Sara Burgos-López, Jéssica García, L. Moya‐Albiol
Background: The ability of scientists and clinicians to detect the therapeutic needs of patients with brain damage has increased in recent years. In this sense, many studies have signaled that individuals tend to experience an increase in irritability after suffering brain damage, with some patients even showing sudden aggressive outbursts. This increase in anger expression in these patients could be explained by executive functioning alterations (or executive dysfunctions), given their role in goal-oriented behaviors, along with emotional dysregulations such as alexithymia (e.g., difficulties recognizing and verbalizing feelings) and anger rumination (e.g., tendency to recall thoughts regarding experiences of frustration or anger). Therefore, it is essential to understand the mechanisms that contribute to and/or facilitate anger expression in patients with brain damage. Methods: In this regard, the main objective of this study is to assess whether executive dysfunctions (assessed with the Frontal Systems Behavior Scale) would explain anger expression (measured with the Reactive and Proactive Aggression Questionnaire) in patients with brain damage (n = 23; mean age: 56.61 ± 10.68; 57% men) compared to controls (n = 24; mean age: 60.96 ± 9.25; 33% men), paying special attention to potential moderators of this association such as alexithymia (analyzed with the Toronto Alexithymia Scale-20) and anger rumination (assessed with the Anger Rumination Scale). Results: The results of the current investigation led us to conclude that anger expression in patients with brain damage was partly explained by executive dysfunction, especially in those patients who scored high in alexithymia. This model was not significant among controls. Conclusions: Thus, we highlight the importance of targeting certain psychological alterations, such as alexithymia, when implementing psychotherapeutic programs as an adjuvant to cognitive training focused on cognitive deficits (e.g., executive dysfunctions). This, in turn, would support the full recovery of individuals who have experienced brain damage.
背景:近年来,科学家和临床医生检测脑损伤患者治疗需求的能力不断提高。从这个意义上说,许多研究表明,遭受脑损伤后的人往往会变得更加易怒,有些患者甚至会表现出突然的攻击性爆发。这些患者愤怒情绪表达增多的原因可能是执行功能的改变(或执行功能障碍),因为执行功能在目标导向行为中扮演着重要角色,同时也可能是情感调节障碍,如条件反射(如难以识别和用语言表达情感)和愤怒反刍(如倾向于回忆与挫折或愤怒经历有关的想法)。因此,了解导致和/或促进脑损伤患者愤怒表达的机制至关重要。方法:在这方面,本研究的主要目的是评估脑损伤患者(n = 23;平均年龄:56.61±10.68;57%为男性)与对照组(n = 24;平均年龄:60.96±9.25;33%为男性)相比,特别注意这种关联的潜在调节因素,如反思症(用多伦多反思症量表-20分析)和愤怒反刍(用愤怒反刍量表评估)。结果本次调查的结果使我们得出结论,脑损伤患者的愤怒表达部分是由执行功能障碍引起的,尤其是在那些亚历山大症得分较高的患者中。这一模型在对照组中并不显著。结论:因此,我们强调了在实施心理治疗计划时,针对某些心理改变(如情感障碍)进行治疗的重要性,这些心理改变是认知训练的辅助手段,而认知训练的重点是认知缺陷(如执行功能障碍)。反过来,这也有助于脑损伤患者的全面康复。
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引用次数: 0
Efficacy of Naltrexone/Bupropion in Treatment of Binge Eating: A Systematic Review and Meta-Analysis 纳曲酮/安非他酮治疗暴食的疗效:系统回顾与元分析
Pub Date : 2024-07-02 DOI: 10.3390/psychiatryint5030022
Mostafa Hossam-Eldin Moawad, M. A. Sadeq, Abdallah Abbas, Reem Mohammed Farouk Ghorab, Ibrahim Serag, Mohamed Hendawy, M. Alkasaby
Background: As the most widespread eating disorder in the world now, binge eating disorder (BED) is a mental condition characterized by recurrent periods of excessive food consumption and an inability to regulate one’s portion sizes. The utilization of a bupropion–naltrexone (NB) combination has been suggested as a potential therapeutic approach for BED. Assessing the effectiveness of NB in the treatment of BED and its accompanying obesity is the purpose of this research. Methods: A comprehensive search was conducted in order to obtain any pertinent articles. PubMed, Scopus, Web of Science, and Cochrane Clinical Trials were consulted against in the databases that were searched. In our final meta-analysis, we incorporated interventional or observational studies that documented the effects of NB therapy for binge eating in adults. We also examined the difference in the mean change between the NB and placebo groups, as well as the disparity in outcomes before and after treatment. Results: This study shows that the use of an NB combination is associated with a statistically significant reduction in the weight, BMI, and Binge Eating Scale (BES) of the patients compared to their weight before treatment with MD: −8.52 (95% CI: −10.01–−6.94, p < 0.00001), MD: −4.95 (95%CI: −9.72–−0.17, p = 0.04), and MD: −7.66 (95%CI: −14.36–0.96, p = 0.02), respectively. The absolute mean change was statistically significantly higher in the drug combination group compared to the placebo group. Conclusions: NB showed efficacy in the improvement of the weight and psychiatric symptoms associated with BED and this provides a promising treatment option.
背景:暴饮暴食症(BED)是目前世界上最普遍的饮食失调症,是一种以反复出现过量进食和无法控制食量为特征的精神疾病。有人建议将安非他酮-纳曲酮(NB)组合作为治疗暴饮暴食症的一种潜在方法。本研究旨在评估 NB 治疗 BED 及其伴随肥胖症的有效性。研究方法:为了获得相关文章,我们进行了全面搜索。所搜索的数据库包括 PubMed、Scopus、Web of Science 和 Cochrane Clinical Trials。在最终的荟萃分析中,我们纳入了记录NB疗法对成年人暴食效果的干预性或观察性研究。我们还研究了 NB 组和安慰剂组之间平均变化的差异,以及治疗前后结果的差异。研究结果本研究表明,与使用 MD 治疗前的体重相比,使用 NB 组合疗法可使患者的体重、体重指数(BMI)和暴食量表(BES)出现统计学意义上的显著下降:-8.52(95% CI:-10.01--6.94,P <0.00001),MD:-4.95(95%CI:-9.72--0.17,p = 0.04),MD:分别为-7.66(95%CI:-14.36-0.96,p = 0.02)。与安慰剂组相比,联合用药组的绝对平均变化显著高于安慰剂组。结论NB对改善与BED相关的体重和精神症状具有疗效,是一种很有前景的治疗方案。
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引用次数: 0
Job Satisfaction, Mental Symptoms, and Well-Being in Adult Workers: A Gender Analysis 成年工人的工作满意度、精神症状和幸福感:性别分析
Pub Date : 2024-06-04 DOI: 10.3390/psychiatryint5020018
M. Matud, Ligia Sánchez-Tovar, D. E. Hernández-Lorenzo, David Cobos-Sanchiz
Although studies have found that job satisfaction has an impact on workers’ physical and mental health, research has generally not focused on the psychological well-being of adult workers and a gender differential analysis has not been conducted. The aim of the current research is to determine the importance of job satisfaction for mental symptoms and well-being among adult working women and men. We also examine gender differences in job satisfaction. A non-probability sample of 1977 Spanish workers (51.6% men and 48.4% women) aged between 36 and 65 years was used in this cross-sectional study. Six questionnaires and self-report scales were used to assess the participants. For both men and women, higher job satisfaction was associated with lower depressive, somatic, anxiety, and social dysfunction symptoms; higher life satisfaction; and greater psychological well-being. Hierarchical multiple regression analyses showed that after controlling for the effects of self-esteem and social support, higher job satisfaction predicted greater life satisfaction, fewer mental symptoms, and greater psychological well-being, although the effect of job satisfaction on psychological well-being was somewhat stronger for men than for women. We conclude that job satisfaction is important for the mental health, psychological well-being, and life satisfaction of adult working women and men.
尽管研究发现,工作满意度对工人的身心健康有影响,但研究一般不关注成年工人的心理健康,也没有进行过性别差异分析。当前研究的目的是确定工作满意度对成年男女工人的精神症状和幸福感的重要性。我们还研究了工作满意度的性别差异。这项横断面研究使用了一个非概率样本,其中包括 1977 名年龄在 36 岁至 65 岁之间的西班牙工人(51.6% 为男性,48.4% 为女性)。研究使用了六份问卷和自我报告量表对参与者进行评估。对于男性和女性而言,较高的工作满意度与较低的抑郁、躯体、焦虑和社会功能障碍症状、较高的生活满意度和较高的心理幸福感相关。层次多元回归分析表明,在控制了自尊和社会支持的影响后,较高的工作满意度预示着较高的生活满意度、较少的精神症状和较高的心理幸福感,尽管工作满意度对心理幸福感的影响在某种程度上男性强于女性。我们的结论是,工作满意度对成年职业女性和男性的心理健康、心理幸福感和生活满意度都很重要。
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引用次数: 0
Depressive Disorders and EU Labour Resources—The Problem of Lost Productivity in Highly Developed Economies 抑郁障碍与欧盟劳动力资源--高度发达经济体生产力损失的问题
Pub Date : 2024-04-16 DOI: 10.3390/psychiatryint5020012
A. Jakubowska
Research has shown that mental disorders in working-age individuals are associated with a significant burden of disability, sickness absence, and presenteeism, resulting in lost productivity. This study aims to assess the impact of depressive disorders on the labour markets in the European Union countries, with a particular focus on the disparities between the ‘old’ and ‘new’ EU countries. The study analysed the process of convergence of the burden of depressive disorders among people aged 20–54 in the group of EU-27 countries in the years 1990–2019, using data from the Global Burden of Disease Study 2019. The initial hypothesis of persistent inequalities in the system studied was verified. The study measured years lived with disability (YLD) due to depressive disorders in the working-age population. The analysis revealed that depressive disorders have a significant impact on the highly developed economies of the EU-14 countries. The convergence assessment did not confirm the effect of catching up with more favourable economies over time, and the inequalities observed at the beginning of the analysis period worsened. This study’s results expand upon the existing literature on the consequences of depressive disorders by introducing the perspective of inequalities in the studied area. These inequalities were observed between EU-27 economies with varying levels of socio-economic development.
研究表明,劳动适龄人口的精神障碍与残疾、因病缺勤和旷工造成的重大负担有关,从而导致生产力损失。本研究旨在评估抑郁障碍对欧盟国家劳动力市场的影响,尤其关注 "老 "欧盟国家和 "新 "欧盟国家之间的差异。研究利用《2019 年全球疾病负担研究》(Global Burden of Disease Study 2019)的数据,分析了 1990-2019 年欧盟 27 国集团中 20-54 岁人群抑郁障碍负担的趋同过程。研究系统中持续存在不平等现象的最初假设得到了验证。研究测量了工作年龄人口中因抑郁障碍导致的残疾生活年限(YLD)。分析表明,抑郁障碍对欧盟 14 国中经济高度发达的国家有重大影响。随着时间的推移,趋同性评估并没有证实追赶更有利经济体的效果,分析期开始时观察到的不平等现象更加严重。本研究的结果从研究领域的不平等角度出发,扩展了有关抑郁症后果的现有文献。在社会经济发展水平各不相同的欧盟 27 国经济体之间观察到了这些不平等现象。
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引用次数: 0
Effects of Gender and Social Network Use on High School Students’ Emotional Well-Being during COVID-19 COVID-19 期间性别和社交网络使用对高中生情感健康的影响
Pub Date : 2024-04-09 DOI: 10.3390/psychiatryint5020011
Sabina Mandić, N. Ricijaš, Dora Dodig Hundrić
Various studies conducted during the COVID-19 pandemic have confirmed changes in online behaviour, with young people increasingly using social networks. This trend appears to correlate with a heightened risk of various psychological and emotional problems. The main aim of this study is to explore the patterns of social network use among high school students amidst the pandemic, particularly focusing on the presence of specific emotional problems and potential gender differences. In addition, this study aims to contribute to the existing body of knowledge on the influence of lockdown measures on adolescents. A probabilistic sample of N = 825 students from 20 high schools in Zagreb participated in this study. Alongside basic sociodemographic variables, this study assessed social network habits and emotional problems using the Depression Anxiety Stress Scales 21 (DASS-21). The findings indicate intensive social media engagement during the pandemic. The results of the MANOVA analysis (gender x daily time on social media) show significant effects of both the time spent on social networks and gender on mental health, while no interaction effect was observed. Female students and those who spend more time on social media have higher levels of depression, anxiety, and stress symptoms. These findings underscore the need for addressing emotional problems and habits in the virtual environment of high school students and implementing appropriate preventive and treatment interventions.
在 COVID-19 大流行期间进行的各种研究证实了在线行为的变化,年轻人越来越多地使用社交网络。这一趋势似乎与出现各种心理和情绪问题的风险增加有关。本研究的主要目的是探讨大流行病中高中生使用社交网络的模式,尤其关注特定情绪问题的存在和潜在的性别差异。此外,本研究还旨在为有关封锁措施对青少年影响的现有知识体系做出贡献。来自萨格勒布 20 所高中的 825 名学生参加了此次研究。除基本社会人口变量外,本研究还使用抑郁焦虑压力量表 21 (DASS-21) 评估了社交网络习惯和情绪问题。研究结果表明,在大流行病期间,社交媒体的参与度很高。MANOVA 分析(性别 x 每天使用社交媒体的时间)的结果显示,社交网络使用时间和性别对心理健康都有显著影响,但没有观察到交互影响。女学生和在社交媒体上花费更多时间的学生的抑郁、焦虑和压力症状水平更高。这些发现强调了解决高中生在虚拟环境中的情绪问题和习惯并实施适当的预防和治疗干预措施的必要性。
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引用次数: 0
Effects of a One-Day Experiential Sheep-Rearing Experience on Motivation, Anxiety, and Frontal Lobe Brain Activity in Patients with Chronic Psychiatric Disorders: A Crossover Pilot Study 为期一天的养羊体验对慢性精神障碍患者的动机、焦虑和大脑额叶活动的影响:交叉试验研究
Pub Date : 2024-03-26 DOI: 10.3390/psychiatryint5020010
Nobuko Shimizu, Shingo Ohe, Keigo Asano, Motohiko Ishida
The purpose of this study was to investigate the effects of a one-day sheep-rearing experience on motivation and anxiety levels in patients with chronic mental illness. The study assessed changes in oxytocin and cortisol levels and brain activity in the prefrontal cortex, which is known to be associated with emotion and motivation. The study employed a non-randomized controlled trial design, with participants receiving both an intervention day (sheep rearing) and a control day (usual psychiatric day care) in a crossover fashion. Written informed consent was obtained from all participants. The intervention day consisted of hands-on sheep rearing activities, while the control day consisted of general activities available at the psychiatric day care center. Results showed that the sheep-raising experience had an equal effect on motivation and increased mean oxytocin levels. In addition, significantly more activity was observed in the dorsolateral prefrontal cortex (DLPFC) region of the brain compared to typical psychiatric daycare activities (p < 0.032, p < 0.043). Participants tended to have increased oxytocin levels after sheep rearing, and the activation of the DLPFC has not previously been observed in animal intervention studies. These are new findings in psychiatric occupational therapy that may have effects on social cognition and interpersonal relationships in patients with chronic mental illness.
本研究的目的是调查为期一天的养羊经历对慢性精神病患者的动机和焦虑水平的影响。研究评估了催产素和皮质醇水平的变化以及前额叶皮层的大脑活动,众所周知,前额叶皮层与情绪和动机有关。研究采用了非随机对照试验设计,以交叉方式让参与者同时接受干预日(饲养绵羊)和对照日(通常的精神科日间护理)。所有参与者均已获得书面知情同意。干预日包括亲自动手饲养绵羊的活动,而对照日则包括精神病日间护理中心提供的一般活动。结果表明,养羊体验对动机和催产素平均水平的提高具有同等效果。此外,与典型的精神病日托活动相比,在大脑背外侧前额叶皮层(DLPFC)区域观察到的活动明显增多(p < 0.032,p < 0.043)。参与者在饲养绵羊后往往会增加催产素水平,而 DLPFC 的激活以前从未在动物干预研究中观察到。这些都是精神病职业疗法的新发现,可能会对慢性精神病患者的社会认知和人际关系产生影响。
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引用次数: 0
A Cross-Sectional Study of How Harm Avoidance, Incompleteness and Intolerance of Uncertainty Contribute to Obsessive–Compulsive Disorder in University Students 关于 "伤害回避"、"不完整性 "和 "不确定性不容忍 "如何导致大学生强迫症的横断面研究
Pub Date : 2024-03-06 DOI: 10.3390/psychiatryint5010009
Anna Nisyraiou, Meropi Simou, G. Simos
Research suggests that certain cognitive factors increase the likelihood of developing and maintaining obsessive–compulsive disorder (OCD). Such factors that are often associated with OCD are harm avoidance (HA), incompleteness (INC), and intolerance of uncertainty (IU). The present study aimed to examine the associations of intolerance of uncertainty, incompleteness, and harm avoidance with dimensions of obsessive–compulsive symptoms. Participants were 1128 university students (Mage = 19.42 St.d. = 2.02). Results showed that all subscales of the OCI-R correlated significantly with HA, INC, and IU, confirming the findings of previous studies. HA and INC appear to predict OC symptoms in a significant way. IU appears to correlate and improve the models, although to a lesser degree. The present findings contribute to our better understanding of the relationship between OCD symptoms and underlying cognitive variables and the nature of OCD heterogeneity.
研究表明,某些认知因素会增加患上和维持强迫症(OCD)的可能性。这些经常与强迫症相关的因素包括伤害回避(HA)、不完整性(INC)和不确定性不容忍(IU)。本研究旨在探讨不确定性不容忍、不完整性和伤害回避与强迫症症状的相关性。研究对象为 1128 名大学生(Mage = 19.42 St.d. = 2.02)。结果显示,OCI-R 的所有分量表均与 HA、INC 和 IU 显著相关,证实了之前研究的结果。HA和INC似乎能显著预测OC症状。IU 似乎与模型相关并对模型有所改进,但程度较低。本研究结果有助于我们更好地理解强迫症症状与潜在认知变量之间的关系以及强迫症异质性的本质。
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引用次数: 0
Bone Health in Mood Disorders: A Narrative Review about Clinical and Biological Connections 情绪失调症患者的骨骼健康:关于临床与生物学联系的叙述性综述
Pub Date : 2024-02-18 DOI: 10.3390/psychiatryint5010006
Antonella Maria Pia De Novellis, Giulia Ferrazzi, G. Galeazzi, M. Marchi, Matteo Meloni, L. Pingani, Silvia Ferrari
Evidence about bone health in people affected by psychiatric disorders is limited. This narrative review aims to highlight what is known, up to the present time, about clinical connections between bone health and psychiatric disorders, particularly depressive disorders (DD) and bipolar disorders (BD), in terms of common biological pathways. Besides inflammation, we focused on two molecules of growing interest: neuropeptide Y (NPY) and the neuro-hormone melatonin. Also, the role of psychoactive drugs on bone tissue was explored. For the preparation of this narrative review, the scientific literature of the most recent 7 years from PubMed, Springer Nature, Science Direct (Elsevier), Wiley Online, ResearchGate, and Google Scholar databases was analyzed. Reviewed evidence reveals that people diagnosed with BD or DD have an increased risk of both fractures and osteoporosis; NPY reduces bone loss induced by longer periods of depression and “buffers” psychological stress effects on bone health. MLT shows beneficial effects in osteoporosis and bone healing. Lithium, a mood stabilizer, shows potential bone-protective activity, while antipsychotic and antidepressant treatments may increase the risk of bone tissue damage, though further investigation is needed.
有关精神障碍患者骨骼健康的证据非常有限。这篇叙述性综述旨在从共同的生物通路角度,强调目前已知的有关骨骼健康与精神障碍,尤其是抑郁障碍(DD)和双相情感障碍(BD)之间的临床联系。除了炎症之外,我们还重点研究了两种日益受到关注的分子:神经肽 Y(NPY)和神经激素褪黑激素。此外,我们还探讨了精神药物对骨组织的作用。为了编写这篇叙述性综述,我们分析了 PubMed、Springer Nature、Science Direct (Elsevier)、Wiley Online、ResearchGate 和 Google Scholar 数据库中最近 7 年的科学文献。综述证据显示,被诊断患有 BD 或 DD 的人骨折和骨质疏松症的风险都会增加;NPY 可减少因长期抑郁而导致的骨质流失,并 "缓冲 "心理压力对骨骼健康的影响。MLT 对骨质疏松症和骨愈合有好处。锂是一种情绪稳定剂,具有潜在的骨骼保护作用,而抗精神病和抗抑郁治疗可能会增加骨组织损伤的风险,但仍需进一步研究。
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引用次数: 0
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Psychiatry International
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