{"title":"S100 calcium‑binding protein A16 suppresses the osteogenic differentiation of rat bone marrow mesenchymal stem cells by inhibiting SMAD family member 4 signaling","authors":"Jing Xin, Zhaoxu Wang, Yanju Shen, Jing Bai, Yafei Shen","doi":"10.3892/etm.2024.12538","DOIUrl":"https://doi.org/10.3892/etm.2024.12538","url":null,"abstract":"","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"43 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahir Fadel, Amani J Basaeed, Mohammed Ashi, H. Aljaaly
{"title":"Vastus lateralis flap for trochanteric sarcoma reconstruction following prior main pedicle dissection: A case report","authors":"Zahir Fadel, Amani J Basaeed, Mohammed Ashi, H. Aljaaly","doi":"10.3892/etm.2024.12537","DOIUrl":"https://doi.org/10.3892/etm.2024.12537","url":null,"abstract":"","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"82 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140709147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xingmei Cao, Z. Ye, Mingyu Jin, Shuai Yan, Xiantao Song, Rong-chong Huang
[This corrects the article DOI: 10.3892/etm.2018.6646.].
[This corrects the article DOI: 10.3892/etm.2018.6646.].
{"title":"[Corrigendum] Downregulated caveolin‑1 expression serves a potential role in coronary artery spasm by inducing nitric oxide production in vitro","authors":"Xingmei Cao, Z. Ye, Mingyu Jin, Shuai Yan, Xiantao Song, Rong-chong Huang","doi":"10.3892/etm.2024.12535","DOIUrl":"https://doi.org/10.3892/etm.2024.12535","url":null,"abstract":"[This corrects the article DOI: 10.3892/etm.2018.6646.].","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"593 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study evaluated the immediate and 1-year postoperative outcomes of 14 patients with ruptured Valsalva aneurysmal sinus (RSVA) using symmetric ventricular septal defect (VSD) occluder for transcatheter closure (TCC). The sites of rupture were from the non-coronary sinus to the right atrium (RA) in 10 cases (71.4%), the right coronary sinus (RCS) to the RA in 3 cases (21.4%) and the RCS to the right ventricle in 1 case (7.2%). The defects (5-11 mm) were closed with a symmetrical VSD device. During the follow-up (12 months), the enlarged heart of the patients had significantly shrunk and the NYHA improved after closure. In 1 case, a moderate residual shunt was present and the patient suffered from hemolysis at 2 h after the operation, and 1 patient was transferred to surgery for aortic regurgitation 1 year after the initial treatment of RSVA. In conclusion, the TCC of RSVA with the China made symmetrical VSD occluder is safe and effective.
{"title":"An observational study of symmetrical VSD occluder for transcatheter closure of ruptured sinus of Valsalva aneurysm","authors":"Wei Chen, Tongbin Li, Xiaolin Lei, Haitao Liu","doi":"10.3892/etm.2024.12532","DOIUrl":"https://doi.org/10.3892/etm.2024.12532","url":null,"abstract":"This study evaluated the immediate and 1-year postoperative outcomes of 14 patients with ruptured Valsalva aneurysmal sinus (RSVA) using symmetric ventricular septal defect (VSD) occluder for transcatheter closure (TCC). The sites of rupture were from the non-coronary sinus to the right atrium (RA) in 10 cases (71.4%), the right coronary sinus (RCS) to the RA in 3 cases (21.4%) and the RCS to the right ventricle in 1 case (7.2%). The defects (5-11 mm) were closed with a symmetrical VSD device. During the follow-up (12 months), the enlarged heart of the patients had significantly shrunk and the NYHA improved after closure. In 1 case, a moderate residual shunt was present and the patient suffered from hemolysis at 2 h after the operation, and 1 patient was transferred to surgery for aortic regurgitation 1 year after the initial treatment of RSVA. In conclusion, the TCC of RSVA with the China made symmetrical VSD occluder is safe and effective.","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"76 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140741519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina Keramida, I. Papoulidis, Efterpi Pappa, Thomas Liehr, Konstantinos Kalmantis, A. Gerede, Efterpi Pavlidou, Michael B. Petersen, E. Manolakos
Numerous rearrangements in the 8p23 chromosomal region have been reported; included in these rearrangements are isolated deletions in this area. Such deletions are associated with a wide range of phenotypic characteristics, including motor impairment, epilepsy, intellectual disability, cardiac defects and seizures. The present study describes the case of a 30-year-old asymptomatic man that carries a de novo deletion in 8p23.2-p23.3. Molecular karyotyping indicated that the detected deletion involves genes that are in the critical region which is hypothesized to be responsible for the phenotypic characteristics associated with such deletions. The normal phenotype of the patient supports the hypothesis that there is incomplete penetrance of 8p23.2-p23.3 deletions.
{"title":"An asymptomatic male individual carrying a 5.72 Mb de novo deletion in 8p23.2‑p23.3: A case report.","authors":"Christina Keramida, I. Papoulidis, Efterpi Pappa, Thomas Liehr, Konstantinos Kalmantis, A. Gerede, Efterpi Pavlidou, Michael B. Petersen, E. Manolakos","doi":"10.3892/etm.2024.12529","DOIUrl":"https://doi.org/10.3892/etm.2024.12529","url":null,"abstract":"Numerous rearrangements in the 8p23 chromosomal region have been reported; included in these rearrangements are isolated deletions in this area. Such deletions are associated with a wide range of phenotypic characteristics, including motor impairment, epilepsy, intellectual disability, cardiac defects and seizures. The present study describes the case of a 30-year-old asymptomatic man that carries a de novo deletion in 8p23.2-p23.3. Molecular karyotyping indicated that the detected deletion involves genes that are in the critical region which is hypothesized to be responsible for the phenotypic characteristics associated with such deletions. The normal phenotype of the patient supports the hypothesis that there is incomplete penetrance of 8p23.2-p23.3 deletions.","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"142 1","pages":"241"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140748759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crucial role of lncRNA NONHSAG037054.2 and GABPA, and their related functional networks, in ankylosing spondylitis","authors":"Penglei Cui, Yanzhuo Zhang, Chao Wang, Bin Xiao, Qianqian Wang, Liang Zhang, Hongchao Li, Chengai Wu, Wei Tian","doi":"10.3892/etm.2024.12525","DOIUrl":"https://doi.org/10.3892/etm.2024.12525","url":null,"abstract":"","PeriodicalId":508388,"journal":{"name":"Experimental and Therapeutic Medicine","volume":"16 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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