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The trends of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immunoinflammatory index in patients with intracerebral hemorrhage and clinical value in predicting pneumonia 30 days after surgery 脑出血患者中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值和全身免疫炎症指数的变化趋势及预测术后 30 天肺炎的临床价值
Pub Date : 2024-05-01 DOI: 10.1016/j.wneu.2024.05.048
Jian Zhang, Chunlong Liu, Xiong Xiao, Haojie Xie, Yonghui Zhang, Yang Hong, Yong Zhang
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引用次数: 0
Analysis of Spinopelvic Parameters and Lumbar Lordosis in Patients with Transitional Lumbosacral Vertebrae, with Special Reference to Sacralization and Lumbarization 腰骶椎过渡患者的脊柱参数和腰椎后凸分析,特别是骶化和腰椎后凸分析
Pub Date : 2024-01-01 DOI: 10.1016/j.wneu.2024.01.056
H. Karabağ, A. Iplikcioglu
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引用次数: 0
Random Forest-Based Prediction of Outcome and Mortality in Patients with Traumatic Brain Injury Undergoing Primary Decompressive Craniectomy. 基于随机森林的创伤性脑损伤患者行颅底减压切除术的预后和死亡率预测。
IF 2 Pub Date : 2021-04-01 Epub Date: 2021-01-12 DOI: 10.1016/j.wneu.2021.01.002
Martin Hanko, Marián Grendár, Pavol Snopko, René Opšenák, Juraj Šutovský, Martin Benčo, Jakub Soršák, Kamil Zeleňák, Branislav Kolarovszki

Background: Various prognostic models are used to predict mortality and functional outcome in patients after traumatic brain injury with a trend to incorporate machine learning protocols. None of these models is focused exactly on the subgroup of patients indicated for decompressive craniectomy. Evidence regarding efficiency of this surgery is still incomplete, especially in patients undergoing primary decompressive craniectomy with evacuation of traumatic mass lesions.

Methods: In a prospective study with a 6-month follow-up period, we assessed postoperative outcome and mortality of 40 patients who underwent primary decompressive craniectomy for traumatic brain injuries during 2018-2019. The results were analyzed in relation to a wide spectrum of preoperatively available demographic, clinical, radiographic, and laboratory data. Random forest algorithms were trained for prediction of both mortality and unfavorable outcome, with their accuracy quantified by area under the receiver operating curves (AUCs) for out-of-bag samples.

Results: At the end of the follow-up period, we observed mortality of 57.5%. Favorable outcome (Glasgow Outcome Scale [GOS] score 4-5) was achieved by 30% of our patients. Random forest-based prediction models constructed for 6-month mortality and outcome reached a moderate predictive ability, with AUC = 0.811 and AUC = 0.873, respectively. Random forest models trained on handpicked variables showed slightly decreased AUC = 0.787 for 6-month mortality and AUC = 0.846 for 6-month outcome and increased out-of-bag error rates.

Conclusions: Random forest algorithms show promising results in prediction of postoperative outcome and mortality in patients undergoing primary decompressive craniectomy. The best performance was achieved by Classification Random forest for 6-month outcome.

背景:各种预后模型被用于预测创伤性脑损伤后患者的死亡率和功能结局,并有纳入机器学习协议的趋势。这些模型都没有准确地集中在指征减压颅骨切除术的患者亚组上。关于这种手术的有效性的证据仍然不完整,特别是在接受初级减压颅骨切除术并清除创伤性肿块病变的患者中。方法:在一项为期6个月随访期的前瞻性研究中,我们评估了2018-2019年40例创伤性脑损伤行颅脑减压手术的患者的术后预后和死亡率。结果与术前可获得的广泛的人口统计学、临床、放射学和实验室数据进行了分析。随机森林算法被训练用于预测死亡率和不良结果,其准确性通过袋外样本的接受者工作曲线下面积(auc)来量化。结果:随访结束时,死亡率为57.5%。30%的患者获得了良好的预后(格拉斯哥预后量表[GOS]评分4-5分)。基于随机森林的6个月死亡率和预后预测模型达到中等预测能力,AUC分别为0.811和0.873。在精挑细选的变量上训练的随机森林模型显示,6个月死亡率的AUC = 0.787, 6个月预后的AUC = 0.846略有下降,袋子外错误率增加。结论:随机森林算法在预测初次颅脑减压切除术患者的术后预后和死亡率方面显示出良好的结果。分类随机森林在6个月的预后中表现最佳。
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引用次数: 21
PulseRider Use in Ruptured Basilar Apex Aneurysms. PulseRider在破裂基底动脉瘤中的应用。
IF 2 Pub Date : 2019-07-01 Epub Date: 2019-04-10 DOI: 10.1016/j.wneu.2019.04.042
Kyle P O'Connor, Allison E Strickland, Bradley N Bohnstedt

Background: The PulseRider (Pulsar Vascular, Inc, Los Gatos, California, USA) device was developed to treat wide-neck aneurysms, and the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Trial showed efficacy in the treatment of unruptured wide-neck aneurysms. Our case series demonstrates the use of the PulseRider device in the treatment of ruptured wide-neck aneurysms.

Case description: The 2 patients in our series presented with subarachnoid hemorrhage secondary to ruptured basilar apex aneurysms. The patients were taken to the neurointervention suite for embolization of their aneurysms with the PulseRider and platinum microcoils.

Conclusions: In both cases, a Roy Raymond class III embolization was achieved. The patients recovered from their subarachnoid hemorrhage and were discharged with resolution of their symptoms. The presented cases document the safety and efficacy of treating ruptured aneurysms with the PulseRider device.

背景:PulseRider (Pulsar Vascular, Inc, Los Gatos, California, USA)装置被开发用于治疗宽颈动脉瘤,并且辅助神经血管支持的宽颈动脉瘤栓塞和重建(ANSWER)试验显示治疗未破裂的宽颈动脉瘤有效。我们的病例系列展示了PulseRider装置在治疗破裂的宽颈动脉瘤中的应用。病例描述:我们报告的2例患者均为颅底动脉瘤破裂后的蛛网膜下腔出血。患者被带到神经介入组,用PulseRider和铂微线圈栓塞他们的动脉瘤。结论:两例患者均行Roy Raymond III级栓塞术。患者均从蛛网膜下腔出血中恢复,症状缓解出院。这些病例证明了使用PulseRider装置治疗动脉瘤破裂的安全性和有效性。
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引用次数: 6
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World Neurosurgery
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