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Journal of Clinical and Translational Science最新文献

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Understanding Individual Health-Related Social Needs in the Context of Area-Level Social Determinants of Health: The Case for Granularity 在地区级健康社会决定因素的背景下了解与健康相关的个人社会需求:细化的理由
Pub Date : 2024-04-16 DOI: 10.1017/cts.2024.519
Andrew Telzak, Samantha R Levano, Jessica Haughton, E. Chambers, Kevin P. Fiori
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引用次数: 0
What PIs Want When Hiring a Clinical Research Coordinator 首席研究员在聘用临床研究协调员时的要求
Pub Date : 2024-04-15 DOI: 10.1017/cts.2024.505
E. Fisher, Rebecca Thomas, Ikseon Choi, Linda McCauley
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引用次数: 0
Measuring Concordance and Discordance between Selected Individual Characteristics and Corresponding Neighborhood-level Social Determinants of Health 衡量选定个人特征与相应邻里层面社会健康决定因素之间的一致性和不一致性
Pub Date : 2024-04-15 DOI: 10.1017/cts.2024.517
K. M. Ngai, Andrew Maroko, Saadiyah Bilal, Marcee Wilder, Lauren Gordon, Lynne D. Richardson
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引用次数: 0
The Health Equity Explorer: An open-source resource for distributed health equity visualization and research across common data models 健康公平资源管理器:用于分布式健康公平可视化和通用数据模型研究的开源资源
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.500
William G. Adams, Sarah Gasman, Ariel L. Beccia, Liza Fuentes
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引用次数: 0
The impact of social-environmental factors on IQ in syndromic intellectual developmental disabilities 社会环境因素对综合症智力发育障碍患者智商的影响
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.510
Walker S. McKinney, Desireé N. Williford, Leonard Abbeduto, Lauren M. Schmitt
Despite having the same underlying genetic etiology, individuals with the same syndromic form of intellectual developmental disability (IDD) show a large degree of interindividual differences in cognition and IQ. Research indicates that up to 80% of the variation in IQ scores among individuals with syndromic IDDs is attributable to nongenetic effects, including social-environmental factors. In this narrative review, we summarize evidence of the influence that factors related to economic stability (focused on due to its prevalence in existing literature) have on IQ in individuals with syndromic IDDs. We also highlight the pathways through which economic stability is hypothesized to impact cognitive development and drive individual differences in IQ among individuals with syndromic IDDs. We also identify broader social-environmental factors (e.g., social determinants of health) that warrant consideration in future research, but that have not yet been explored in syndromic IDDs. We conclude by making recommendations to address the urgent need for further research into other salient factors associated with heterogeneity in IQ. These recommendations ultimately may shape individual- and community-level interventions and may inform systems-level public policy efforts to promote the cognitive development of and improve the lived experiences of individuals with syndromic IDDs.
尽管具有相同的潜在遗传病因,但具有相同综合征形式智力发育障碍(IDD)的个体在认知和智商方面却表现出很大程度的个体间差异。研究表明,综合征型 IDD 患者的智商得分差异中高达 80% 可归因于非遗传效应,包括社会环境因素。在这篇叙事性综述中,我们总结了经济稳定性相关因素(因其在现有文献中普遍存在而被重点关注)对综合征 IDD 患者智商影响的证据。我们还强调了假设经济稳定性影响认知发展并导致综合征 IDD 患者智商个体差异的途径。我们还确定了更广泛的社会环境因素(如健康的社会决定因素),这些因素值得在未来的研究中加以考虑,但尚未对综合症 IDD 进行探讨。最后,我们提出了一些建议,以满足进一步研究与智商异质性相关的其他突出因素的迫切需要。这些建议最终可能会形成个人和社区层面的干预措施,并为系统层面的公共政策提供信息,以促进综合症 IDD 患者的认知发展并改善其生活体验。
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引用次数: 0
Screening tools to address social determinants of health in the United States: A systematic review 美国解决健康问题社会决定因素的筛查工具:系统回顾
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.506
Mahdi Neshan, Vennila Padmanaban, D. Tsilimigras, S. Obeng-Gyasi, Naleef Fareed, T. Pawlik
The Centers for Medicare & Medicaid Services have mandated that hospitals implement measures to screen social determinants of health (SDoH). We sought to report on available SDoH screening tools. PubMed, Scopus, Web of Science, as well as the grey literature were searched (1980 to November 2023). The included studies were US-based, written in English, and examined a screening tool to assess SDoH. Thirty studies were included in the analytic cohort. The number of questions in any given SDoH assessment tool varied considerably and ranged from 5 to 50 (mean: 16.6). A total of 19 SDoH domains were examined. Housing (n = 23, 92%) and safety/violence (n = 21, 84%) were the domains assessed most frequently. Food/nutrition (n = 17, 68%), income/financial (n = 16, 64%), transportation (n = 15, 60%), family/social support (n = 14, 56%), utilities (n = 13, 52%), and education/literacy (n = 13, 52%) were also commonly included domains in most screening tools. Eighteen studies proposed specific interventions to address SDoH. SDoH screening tools are critical to identify various social needs and vulnerabilities to help develop interventions to address patient needs. Moreover, there is marked heterogeneity of SDoH screening tools, as well as the significant variability in the SDoH domains assessed by currently available screening tools.
美国医疗保险与医疗补助服务中心(Centers for Medicare & Medicaid Services)规定,医院必须采取措施筛查健康的社会决定因素(SDoH)。我们试图报告现有的 SDoH 筛查工具。我们检索了 PubMed、Scopus、Web of Science 以及灰色文献(1980 年至 2023 年 11 月)。纳入的研究均以美国为基地,用英语撰写,并检查了评估 SDoH 的筛查工具。分析队列中包括 30 项研究。SDoH 评估工具的问题数量差异很大,从 5 个到 50 个不等(平均值:16.6 个)。共研究了 19 个 SDoH 领域。住房(n = 23,92%)和安全/暴力(n = 21,84%)是评估频率最高的领域。食物/营养(n = 17,68%)、收入/财务(n = 16,64%)、交通(n = 15,60%)、家庭/社会支持(n = 14,56%)、水电(n = 13,52%)和教育/识字(n = 13,52%)也是大多数筛查工具中常见的领域。18 项研究提出了针对 SDoH 的具体干预措施。SDoH 筛查工具对于识别各种社会需求和脆弱性至关重要,有助于制定干预措施来满足患者的需求。此外,SDoH 筛查工具存在明显的异质性,目前可用的筛查工具所评估的 SDoH 领域也存在显著差异。
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引用次数: 0
Breaking barriers in trauma research: a narrative review of opportunities to leverage veterinary trauma for accelerated translation to clinical solutions for pets and people 打破创伤研究中的障碍:对利用兽医创伤加速转化为宠物和人类临床解决方案的机会进行叙述性审查
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.513
Kelly E Hall, Claire Tucker, Julie Dunn, Tracy L Webb, Sarah A Watts, Emrys Kirkman, Julien Guillaumin, Guillaume L. Hoareau, Heather F Pidcoke
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引用次数: 0
Impact of financial compensation on enrollment and participation in a remote, mobile-app based research study 经济补偿对注册和参与基于移动应用程序的远程研究的影响
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.515
Shelby Meier, A. Cheng, Maeve Tischbein, Cathy Shyr, Rebecca N. Jerome, Terri L. Edwards, Mary Stroud, Consuelo H. Wilkins, Paul A. Harris
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引用次数: 0
Identifying and Addressing Social Determinants of Health to Improve Patient-Centered Care 确定并解决健康的社会决定因素,改善以患者为中心的护理
Pub Date : 2024-04-05 DOI: 10.1017/cts.2024.511
Neil Kalsi, Denai Gordon, Jenenne Geske
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引用次数: 0
Trends in publication and levels of social determinants of health reporting in Journal of Clinical and Translational Science from 2017 to 2023 2017 年至 2023 年《临床与转化科学杂志》上健康的社会决定因素报告的发表趋势和水平
Pub Date : 2024-04-02 DOI: 10.1017/cts.2024.508
Yulia A. Levites Strekalova, Xiangren Wang, Orlando Sanchez, Sara Midence
Social determinants of health affect clinical and translational research processes and outcomes but remain underreported in empirical studies. This scoping review examined the rate and types of social determinants of health (SDoH) variables included in the JCTS translational research studies published between 2017 and 2023 and included 129 studies. Most papers (91.7%) reported at least one SDoH variable with age, race and ethnicity, and sex included most often. Future studies to inform the role of SDoH data in translational research and science are recommended, and a draft SDoH data checklist is provided.
健康的社会决定因素会影响临床和转化研究的过程和结果,但在实证研究中的报道仍然不足。本范围界定综述考察了2017年至2023年间发表的JCTS转化研究中包含的健康社会决定因素(SDoH)变量的比例和类型,共纳入129项研究。大多数论文(91.7%)至少报告了一个 SDoH 变量,其中年龄、种族和民族以及性别被纳入的频率最高。建议今后开展研究,以了解 SDoH 数据在转化研究和科学中的作用,并提供了 SDoH 数据清单草案。
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引用次数: 0
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Journal of Clinical and Translational Science
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