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Advances in Virus Research最新文献

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Structural insights into coronavirus entry 冠状病毒进入的结构洞察
2区 医学 Q1 Medicine Pub Date : 2019-08-22 DOI: 10.1016/bs.aivir.2019.08.002
A. Tortoricia, David Veeslera
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引用次数: 614
Entry of bunyaviruses into plants and vectors. 布尼亚病毒进入植物和媒介。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/bs.aivir.2019.07.001
Yuting Chen, M. Dessau, D. Rotenberg, David A. Rasmussen, A. Whitfield
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引用次数: 17
Hantavirus entry: Perspectives and recent advances. 汉坦病毒进入:观点和最新进展。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.07.002
E. Mittler, M. Dieterle, L. Kleinfelter, Megan M. Slough, K. Chandran, R. Jangra
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引用次数: 53
The viral replication organelles within cells studied by electron microscopy. 通过电子显微镜研究细胞内的病毒复制细胞器。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 Epub Date: 2019-08-19 DOI: 10.1016/bs.aivir.2019.07.005
Martin Sachse, Isabel Fernández de Castro, Raquel Tenorio, Cristina Risco

Transmission electron microscopy (TEM) has been crucial to study viral infections. As a result of recent advances in light and electron microscopy, we are starting to be aware of the variety of structures that viruses assemble inside cells. Viruses often remodel cellular compartments to build their replication factories. Remarkably, viruses are also able to induce new membranes and new organelles. Here we revise the most relevant imaging technologies to study the biogenesis of viral replication organelles. Live cell microscopy, correlative light and electron microscopy, cryo-TEM, and three-dimensional imaging methods are unveiling how viruses manipulate cell organization. In particular, methods for molecular mapping in situ in two and three dimensions are revealing how macromolecular complexes build functional replication complexes inside infected cells. The combination of all these imaging approaches is uncovering the viral life cycle events with a detail never seen before.

透射电子显微镜(TEM)对研究病毒感染至关重要。随着光镜和电子显微镜技术的不断进步,我们开始认识到病毒在细胞内组装的各种结构。病毒通常会重塑细胞间隙,以建立自己的复制工厂。值得注意的是,病毒还能诱导新的细胞膜和新的细胞器。在此,我们对研究病毒复制细胞器生物生成的最相关成像技术进行了修订。活细胞显微镜、相关光镜和电子显微镜、冷冻-TEM 和三维成像方法揭示了病毒是如何操纵细胞组织的。特别是二维和三维原位分子图谱方法,揭示了大分子复合物如何在受感染细胞内构建功能性复制复合物。所有这些成像方法的结合正在以前所未有的细节揭示病毒生命周期事件。
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引用次数: 0
Key checkpoints in the movement of plant viruses through the host. 植物病毒通过宿主运动的关键检查点。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.05.001
J. Navarro, J. Sánchez-Navarro, V. Pallás
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引用次数: 44
Structural mass spectrometry goes viral. 结构质谱法走红。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/bs.aivir.2019.07.003
Jasmin Dülfer, A. Kádek, Janine-Denise Kopicki, Boris Krichel, C. Uetrecht
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引用次数: 27
Contributors 贡献者
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/s0065-3527(19)30050-8
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引用次数: 0
Structural and cellular biology of rhabdovirus entry. 横纹肌病毒侵入的结构和细胞生物学。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.05.003
Laura Belot, A. Albertini, Y. Gaudin
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引用次数: 27
Gammaherpesvirus entry and fusion: A tale how two human pathogenic viruses enter their host cells. 伽玛疱疹病毒进入和融合:两种人类致病性病毒如何进入宿主细胞的故事。
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.05.006
Britta S. Möhl, Jia Chen, R. Longnecker
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引用次数: 23
Copyright 版权
2区 医学 Q1 Medicine Pub Date : 2019-01-01 DOI: 10.1016/s0065-3527(19)30006-5
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引用次数: 0
期刊
Advances in Virus Research
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