首页 > 最新文献

Journal of Medical and Health Studies最新文献

英文 中文
Functionalized Mesoporous Silica Nanoparticles as Potential Drug Delivery Vehicle against Colorectal Cancer 功能化介孔二氧化硅纳米粒子作为潜在的结直肠癌药物输送载体
Pub Date : 2024-08-09 DOI: 10.32996/jmhs.2024.5.3.7
Mahadi Hasan, Md. Khalil, Miah Pathan, Md. Faisal Kabir
This study explores the development of mesoporous silica nanoparticles (MSNs) as an advanced platform for the targeted delivery of doxorubicin hydrochloride (DOX), a widely used chemotherapeutic agent. Utilizing a modified sol-gel process, MSNs were synthesized and functionalized with amino (MSN-NH2) and carboxyl (MSN-COOH) groups to enhance their physicochemical properties and drug delivery efficacy. Comprehensive characterization through scanning electron microscopy (SEM) and Powder X-ray diffraction (PXRD) confirmed the successful synthesis of spherical MSNs with a uniform internal structure and mesoporous nature. Zeta potential measurements highlighted the impact of surface functionalization on the surface charge of the nanoparticles, revealing positive and significantly negative charges for MSN-NH2 and MSN-COOH respectively. This study further investigated the pH-responsive drug release profiles of DOX-loaded MSNs under physiological (pH 7.4) and tumor-mimicking acidic (pH 5.5) conditions. The results demonstrated a controlled release at pH 7.4, minimizing systemic toxicity, and a significantly enhanced release at pH 5.5, targeting the acidic tumor microenvironment for improved therapeutic efficacy. The findings underscore the potential of functionalized MSNs as a versatile nanocarrier system for cancer therapy, offering a promising strategy to increase the therapeutic index of DOX and reduce adverse effects. This work contributes valuable insights into the design and application of nanoparticle-based drug delivery systems, paving the way for future pre-clinical applications and advancements in targeted colorectal cancer treatments.
本研究探讨了介孔二氧化硅纳米颗粒(MSNs)的开发,将其作为靶向递送盐酸多柔比星(DOX)(一种广泛使用的化疗药物)的先进平台。利用改进的溶胶-凝胶工艺合成了 MSNs,并对其进行了氨基(MSN-NH2)和羧基(MSN-COOH)官能化处理,以增强其理化性质和给药效果。通过扫描电子显微镜(SEM)和粉末 X 射线衍射(PXRD)进行的综合表征证实,成功合成了具有均匀内部结构和介孔性质的球形 MSN。Zeta 电位测量强调了表面官能化对纳米粒子表面电荷的影响,发现 MSN-NH2 和 MSN-COOH 分别带有正电荷和明显的负电荷。本研究进一步研究了在生理条件(pH 值为 7.4)和模拟肿瘤的酸性条件(pH 值为 5.5)下负载 DOX 的 MSN 的 pH 值响应药物释放曲线。结果表明,在 pH 值为 7.4 的条件下,药物释放得到控制,从而最大限度地降低了全身毒性;而在 pH 值为 5.5 的条件下,药物释放明显增强,从而针对酸性肿瘤微环境提高了疗效。这些发现强调了功能化 MSNs 作为一种多功能纳米载体系统用于癌症治疗的潜力,为提高 DOX 的治疗指数和减少不良反应提供了一种前景广阔的策略。这项研究为基于纳米颗粒的给药系统的设计和应用提供了宝贵的见解,为未来的临床前应用和结直肠癌靶向治疗的进步铺平了道路。
{"title":"Functionalized Mesoporous Silica Nanoparticles as Potential Drug Delivery Vehicle against Colorectal Cancer","authors":"Mahadi Hasan, Md. Khalil, Miah Pathan, Md. Faisal Kabir","doi":"10.32996/jmhs.2024.5.3.7","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.3.7","url":null,"abstract":"This study explores the development of mesoporous silica nanoparticles (MSNs) as an advanced platform for the targeted delivery of doxorubicin hydrochloride (DOX), a widely used chemotherapeutic agent. Utilizing a modified sol-gel process, MSNs were synthesized and functionalized with amino (MSN-NH2) and carboxyl (MSN-COOH) groups to enhance their physicochemical properties and drug delivery efficacy. Comprehensive characterization through scanning electron microscopy (SEM) and Powder X-ray diffraction (PXRD) confirmed the successful synthesis of spherical MSNs with a uniform internal structure and mesoporous nature. Zeta potential measurements highlighted the impact of surface functionalization on the surface charge of the nanoparticles, revealing positive and significantly negative charges for MSN-NH2 and MSN-COOH respectively. This study further investigated the pH-responsive drug release profiles of DOX-loaded MSNs under physiological (pH 7.4) and tumor-mimicking acidic (pH 5.5) conditions. The results demonstrated a controlled release at pH 7.4, minimizing systemic toxicity, and a significantly enhanced release at pH 5.5, targeting the acidic tumor microenvironment for improved therapeutic efficacy. The findings underscore the potential of functionalized MSNs as a versatile nanocarrier system for cancer therapy, offering a promising strategy to increase the therapeutic index of DOX and reduce adverse effects. This work contributes valuable insights into the design and application of nanoparticle-based drug delivery systems, paving the way for future pre-clinical applications and advancements in targeted colorectal cancer treatments.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"8 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141921704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Various Clinical Manifestation of Omphalomesenteric Duct Remnant in a Child: A Case Report 儿童肠管残留物的各种临床表现:病例报告
Pub Date : 2024-05-16 DOI: 10.32996/jmhs.2024.5.2.8
Jonsinar Silalahi
Omphalomesenteric duct (OMD) remnant is a condition in which the omphalomesenteric duct fails to obliterate completely or partially. Failure in this step can produce various patterns, such as a vitelline cyst, umbilical sinus, polyp, Meckel’s diverticulum, and patent OMD. Various clinical manifestations of OMD rarely occur in one patient. We present the case of omphalomesenteric duct remnant, manifested as anterior wall abdominal mass, intraperitoneal hemorrhage, and obstructive ileus. Case report: A four-year-old girl was referred to our hospital with obstructive ileus and abdominal wall mass on the left lower quadrant. Contrast-enhanced abdominal computed tomography (CT) scan found an irregular cystic mass in the abdominal cavity that adheres to the anterior wall of the abdomen and bowel structure with a fluid-solid level without enhancement. Further medical history was taken and found a history of intermittent watery umbilical discharge that appears three times in 2 years after birth. Omphalomesenteric duct remnant was suspected, then proceed to exploratory laparotomy. We found intraperitoneal hemorrhage and 5x4 centimeters frail mass adhering to the anterior wall of the abdomen on the left side of the umbilicus. Histopathological examination confirmed intestinal tissue, suggesting remnants of the omphalomesenteric duct and pancreatic tissue with a chronic inflammatory pattern. Diagnosing omphalomesenteric duct remnant could be challenging and should be considered a differential diagnosis of obstructive ileus, particularly if persistent umbilical discharges are also present. On the other hand, early diagnosis and appropriate management of persistent umbilical discharge could prevent a greater outcome.
残余脐肠管(OMD)是指脐肠管未能完全或部分闭塞。这一步骤的失败可产生各种形态,如玻璃体囊肿、脐窦、息肉、梅克尔憩室和闭孔 OMD。OMD 的各种临床表现很少出现在一名患者身上。我们介绍了一例表现为前壁腹部肿块、腹腔内出血和梗阻性回肠的脐肠管残留病例。病例报告:一名四岁女童因梗阻性回肠症和左下腹腹壁肿块转诊至我院。对比增强腹部计算机断层扫描(CT)发现腹腔内有一不规则囊性肿块,与腹部前壁和肠道结构粘连,呈液固相平,无强化。进一步询问病史,发现患者有间歇性水样脐分泌物病史,在出生后两年内出现过三次。怀疑有脐肠管残留,于是进行了剖腹探查术。我们发现患者腹腔内出血,脐左侧腹部前壁有一个 5x4 厘米的脆弱肿块。组织病理学检查证实为肠组织,提示有肠套膜管残余和胰腺组织,并伴有慢性炎症。诊断包膜肠管残余可能具有挑战性,应将其作为梗阻性回肠的鉴别诊断,尤其是如果同时出现持续性脐部分泌物。另一方面,对持续性脐分泌物进行早期诊断和适当处理可避免更大的后果。
{"title":"Various Clinical Manifestation of Omphalomesenteric Duct Remnant in a Child: A Case Report","authors":"Jonsinar Silalahi","doi":"10.32996/jmhs.2024.5.2.8","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.2.8","url":null,"abstract":"Omphalomesenteric duct (OMD) remnant is a condition in which the omphalomesenteric duct fails to obliterate completely or partially. Failure in this step can produce various patterns, such as a vitelline cyst, umbilical sinus, polyp, Meckel’s diverticulum, and patent OMD. Various clinical manifestations of OMD rarely occur in one patient. We present the case of omphalomesenteric duct remnant, manifested as anterior wall abdominal mass, intraperitoneal hemorrhage, and obstructive ileus. Case report: A four-year-old girl was referred to our hospital with obstructive ileus and abdominal wall mass on the left lower quadrant. Contrast-enhanced abdominal computed tomography (CT) scan found an irregular cystic mass in the abdominal cavity that adheres to the anterior wall of the abdomen and bowel structure with a fluid-solid level without enhancement. Further medical history was taken and found a history of intermittent watery umbilical discharge that appears three times in 2 years after birth. Omphalomesenteric duct remnant was suspected, then proceed to exploratory laparotomy. We found intraperitoneal hemorrhage and 5x4 centimeters frail mass adhering to the anterior wall of the abdomen on the left side of the umbilicus. Histopathological examination confirmed intestinal tissue, suggesting remnants of the omphalomesenteric duct and pancreatic tissue with a chronic inflammatory pattern. Diagnosing omphalomesenteric duct remnant could be challenging and should be considered a differential diagnosis of obstructive ileus, particularly if persistent umbilical discharges are also present. On the other hand, early diagnosis and appropriate management of persistent umbilical discharge could prevent a greater outcome.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"18 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Professional Registration and Development Pathways: Perspectives of Healthcare Practitioners 专业注册和发展途径导航:医疗从业人员的观点
Pub Date : 2024-05-08 DOI: 10.32996/jmhs.2024.5.2.7
A. Alshamsan, Ameera Alhasani, Alia Aleisa, Yousra Alatiq, Muhammad Althanian, Muhammad Waseem Shahzad, Adel A Al-Shabaan, Mustafa Bodrick, A. Alsukhayri, Rawan Almalki, Safa Alakhdhair, Yasir Sulaiman Abdurahman Almuways
The Saudi Commission for Health Specialties (SCFHS) has undertaken a comprehensive evaluation of its registration and classification services to pinpoint areas for optimization. Recognizing healthcare professionals as essential stakeholders, SCFHS actively solicited their perspectives to better understand their needs and to collect actionable suggestions for service enhancement. Employing a multifaceted research approach, this study utilized focus groups, a large-scale survey involving over 700,000 healthcare practitioners, and comparative benchmarking against selected G-20 nations. The findings indicate a strong desire among practitioners for a reorganisation of the current registration and classification procedures. Notably, there was a consensus for extending the registration period, with a predominant preference for a five-year duration. Participants also advocated for various improvements, such as an increase in Continuing Medical Education (CME) hours, financial cost reductions, and streamlining of registration processes. While benchmarking revealed that SCFHS's existing registration durations are generally on par with other G-20 countries, it also highlighted potential opportunities for diversifying registration types to better meet the needs of healthcare professionals.
沙特卫生专业委员会(SCFHS)对其注册和分类服务进行了全面评估,以确定需要优化的领域。认识到医疗保健专业人员是重要的利益相关者,SCFHS 积极征求他们的意见,以更好地了解他们的需求,并收集可操作的服务改进建议。这项研究采用了多方面的研究方法,包括焦点小组、涉及 70 多万名医疗从业人员的大规模调查,以及与选定的 20 国集团国家的比较基准。研究结果表明,从业人员强烈希望对现行的注册和分类程序进行重组。值得注意的是,与会者一致同意延长注册期限,主要倾向于五年。与会者还主张采取各种改进措施,如增加继续医学教育(CME)时数、降低财务成本和简化注册程序。基准测试表明,南太平洋医疗卫生联合会现有的注册期限总体上与 20 国集团的其他国家持平,但也强调了注册类型多样化的潜在机会,以更好地满足医疗卫生专业人员的需求。
{"title":"Navigating Professional Registration and Development Pathways: Perspectives of Healthcare Practitioners","authors":"A. Alshamsan, Ameera Alhasani, Alia Aleisa, Yousra Alatiq, Muhammad Althanian, Muhammad Waseem Shahzad, Adel A Al-Shabaan, Mustafa Bodrick, A. Alsukhayri, Rawan Almalki, Safa Alakhdhair, Yasir Sulaiman Abdurahman Almuways","doi":"10.32996/jmhs.2024.5.2.7","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.2.7","url":null,"abstract":"The Saudi Commission for Health Specialties (SCFHS) has undertaken a comprehensive evaluation of its registration and classification services to pinpoint areas for optimization. Recognizing healthcare professionals as essential stakeholders, SCFHS actively solicited their perspectives to better understand their needs and to collect actionable suggestions for service enhancement. Employing a multifaceted research approach, this study utilized focus groups, a large-scale survey involving over 700,000 healthcare practitioners, and comparative benchmarking against selected G-20 nations. The findings indicate a strong desire among practitioners for a reorganisation of the current registration and classification procedures. Notably, there was a consensus for extending the registration period, with a predominant preference for a five-year duration. Participants also advocated for various improvements, such as an increase in Continuing Medical Education (CME) hours, financial cost reductions, and streamlining of registration processes. While benchmarking revealed that SCFHS's existing registration durations are generally on par with other G-20 countries, it also highlighted potential opportunities for diversifying registration types to better meet the needs of healthcare professionals.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140998294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of Pre-Operative and Post-Operative Antibiotic Use in Inpatients in Orthopedic Surgery at Dr. H. Moch. Ansari Saleh Banjarmasin Dr. H. Moch.骨科手术住院病人术前术后抗生素使用概况Ansari Saleh Banjarmasin
Pub Date : 2024-03-23 DOI: 10.32996/jmhs.2024.5.1.10
Muhammad Nizar, M. W. Ariyanto
Preoperative and postoperative antibiotics are included in prophylactic antibiotics, which aim to reduce the risk of surgical wound infection. Surgical Site Infection (SSI) is one of the problems of healthcare-associated infections (HAIs). Dr. Hospital H. Moch. Ansari Saleh Banjarmasin is a government hospital that provides many orthopedic surgical procedures and has data related to antibiotic use. This study aims to determine the description of the use of antibiotics as preoperative and postoperative prophylaxis. The research method included a descriptive observational study with a cross-sectional design on medical record data of surgical patients at Dr. RSUD. H. Moch. Ansari Saleh Banjarmasin in August–December 2023, which was taken using a purposive sampling technique with a retrospective approach. Results: 133 samples met the inclusion criteria. The majority of patients were aged 17–25 years (25.6%), the gender was predominantly male (62%), the length of stay was at most 2 days (40.6%), the type of surgery was clean (82%), and they did not have comorbidities (83%). Research shows that cefazolin is most widely used as preoperative prophylaxis by 123 people (92%) and postoperatively by 79 people (59.4%). The study concluded that the most widely used antibiotic for patients undergoing orthopedic surgery at RSUD, Dr. H. Moch. Ansari Saleh Banjarmasin, is cefazolin.
术前和术后抗生素都属于预防性抗生素,旨在降低手术伤口感染的风险。手术部位感染(SSI)是医疗相关感染(HAIs)的问题之一。医院 H. Moch.Ansari Saleh Banjarmasin 是一家政府医院,提供许多骨科外科手术,并拥有与抗生素使用相关的数据。本研究旨在确定抗生素作为术前和术后预防药物的使用情况。研究方法包括一项描述性观察研究,该研究采用横断面设计,以 RSUD.H. Moch.Ansari Saleh Banjarmasin医院的手术患者的病历数据,采用回顾性的目的性抽样技术。结果133 个样本符合纳入标准。大部分患者年龄在 17-25 岁之间(25.6%),性别以男性为主(62%),住院时间最长为 2 天(40.6%),手术类型为清洁手术(82%),无合并症(83%)。研究显示,头孢唑啉作为术前预防用药使用最多的是 123 人(92%),术后使用最多的是 79 人(59.4%)。研究得出结论,RSUD 骨科手术患者最广泛使用的抗生素是 Dr. H. Moch.Ansari Saleh Banjarmasin)最常用的抗生素是头孢唑啉。
{"title":"An Overview of Pre-Operative and Post-Operative Antibiotic Use in Inpatients in Orthopedic Surgery at Dr. H. Moch. Ansari Saleh Banjarmasin","authors":"Muhammad Nizar, M. W. Ariyanto","doi":"10.32996/jmhs.2024.5.1.10","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.10","url":null,"abstract":"Preoperative and postoperative antibiotics are included in prophylactic antibiotics, which aim to reduce the risk of surgical wound infection. Surgical Site Infection (SSI) is one of the problems of healthcare-associated infections (HAIs). Dr. Hospital H. Moch. Ansari Saleh Banjarmasin is a government hospital that provides many orthopedic surgical procedures and has data related to antibiotic use. This study aims to determine the description of the use of antibiotics as preoperative and postoperative prophylaxis. The research method included a descriptive observational study with a cross-sectional design on medical record data of surgical patients at Dr. RSUD. H. Moch. Ansari Saleh Banjarmasin in August–December 2023, which was taken using a purposive sampling technique with a retrospective approach. Results: 133 samples met the inclusion criteria. The majority of patients were aged 17–25 years (25.6%), the gender was predominantly male (62%), the length of stay was at most 2 days (40.6%), the type of surgery was clean (82%), and they did not have comorbidities (83%). Research shows that cefazolin is most widely used as preoperative prophylaxis by 123 people (92%) and postoperatively by 79 people (59.4%). The study concluded that the most widely used antibiotic for patients undergoing orthopedic surgery at RSUD, Dr. H. Moch. Ansari Saleh Banjarmasin, is cefazolin.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":" 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140211099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Associated Factors of Restless Leg Syndrome 不宁腿综合征的发病率和相关因素
Pub Date : 2024-03-16 DOI: 10.32996/jmhs.2024.5.1.9
Mareena Khan, Sofia Robab, Ayman Ahmed, Shreya Rao, Marwa Salem, J. Sreedharan
To assess the prevalence and factors associated with restless leg syndrome among the students at Gulf Medical University. A cross-sectional study was conducted in Gulf Medical University (GMU), Ajman, UAE, upon approval from the Ethics Committee. A self-administered questionnaire was given to gather information from 624 students about Restless Legs Syndrome (RLS), covering things like age, gender, and factors associated with it. Among the students (164 boys and 452 girls), we found that 6.2% had restless leg syndrome. The results of the study showed a connection between restless leg syndrome and factors such as magnesium deficiency, vitamin B12 deficiency, anemia, and sleep disturbance. We did not find a significant link between age and restless leg syndrome in our study, as we focused on people aged 18 and older. In conclusion, we identified the most common factors connected to restless leg syndrome, including low magnesium, low vitamin B12, anemia, and sleep problems. These findings highlight that restless leg syndrome is complex and can affect young adults, with certain nutritional and lifestyle factors playing a role in its occurrence.
评估海湾医科大学学生不安腿综合征的患病率和相关因素。经伦理委员会批准,我们在阿联酋阿治曼海湾医科大学(GMU)开展了一项横断面研究。研究人员向 624 名学生发放了一份自填问卷,以收集有关不安腿综合症(RLS)的信息,包括年龄、性别和相关因素等。我们发现,在这些学生(164 名男生和 452 名女生)中,有 6.2% 的人患有不安腿综合症。研究结果表明,不安腿综合征与镁缺乏、维生素 B12 缺乏、贫血和睡眠障碍等因素有关。在我们的研究中,我们没有发现年龄与不安腿综合征之间有明显的联系,因为我们的研究重点是 18 岁及以上的人群。总之,我们确定了与不安腿综合征有关的最常见因素,包括低镁、低维生素 B12、贫血和睡眠问题。这些研究结果突出表明,不安腿综合征是一种复杂的疾病,可能会影响到年轻的成年人,某些营养和生活方式因素在其发生中起着一定的作用。
{"title":"Prevalence and Associated Factors of Restless Leg Syndrome","authors":"Mareena Khan, Sofia Robab, Ayman Ahmed, Shreya Rao, Marwa Salem, J. Sreedharan","doi":"10.32996/jmhs.2024.5.1.9","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.9","url":null,"abstract":"To assess the prevalence and factors associated with restless leg syndrome among the students at Gulf Medical University. A cross-sectional study was conducted in Gulf Medical University (GMU), Ajman, UAE, upon approval from the Ethics Committee. A self-administered questionnaire was given to gather information from 624 students about Restless Legs Syndrome (RLS), covering things like age, gender, and factors associated with it. Among the students (164 boys and 452 girls), we found that 6.2% had restless leg syndrome. The results of the study showed a connection between restless leg syndrome and factors such as magnesium deficiency, vitamin B12 deficiency, anemia, and sleep disturbance. We did not find a significant link between age and restless leg syndrome in our study, as we focused on people aged 18 and older. In conclusion, we identified the most common factors connected to restless leg syndrome, including low magnesium, low vitamin B12, anemia, and sleep problems. These findings highlight that restless leg syndrome is complex and can affect young adults, with certain nutritional and lifestyle factors playing a role in its occurrence.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"92 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Impact of Socio-Demographic, Health, and Political Factors on COVID-19 Vaccination Attitudes 探索社会人口、健康和政治因素对 COVID-19 疫苗接种态度的影响
Pub Date : 2024-03-14 DOI: 10.32996/jmhs.2024.5.1.8
MD. Ekramul Islam Novel, ✉. M. Sarkar, Aisharyja Roy Puja
This study examines the influence of socio-demographic, health, and political factors on attitudes towards COVID-19 vaccination during 2021-2022. Utilizing data from the General Social Survey (GSS), the research explores the relationships between COVID-19 vaccination status and variables such as confidence in medicine, political views, general health condition, income, education level, and marital status. The analysis employs logistic regression models and Chi-Square tests to assess these relationships. Key findings indicate that higher income and education levels, as well as more liberal political views, are positively associated with vaccination uptake. In contrast, marital status presents a more complex picture, suggesting further exploration is needed. The study highlights the multifaceted nature of vaccination decisions and underscores the importance of tailored public health strategies that address the specific needs and concerns of different demographic groups. The research also acknowledges challenges and limitations, including issues related to causality, confounding factors, data quality, generalizability, response bias, and multicollinearity. Overall, the study contributes valuable insights for policymakers and public health practitioners aiming to enhance vaccination campaigns and policies.
本研究探讨了社会人口、健康和政治因素对 2021-2022 年期间 COVID-19 疫苗接种态度的影响。研究利用一般社会调查(GSS)的数据,探讨了 COVID-19 疫苗接种状况与医学信心、政治观点、总体健康状况、收入、教育水平和婚姻状况等变量之间的关系。分析采用逻辑回归模型和 Chi-Square 检验来评估这些关系。主要研究结果表明,较高的收入和教育水平以及较自由的政治观点与疫苗接种率呈正相关。相比之下,婚姻状况则呈现出更为复杂的情况,表明还需要进一步探讨。这项研究强调了疫苗接种决定的多面性,并强调了针对不同人口群体的具体需求和关注点制定有针对性的公共卫生策略的重要性。研究也承认存在挑战和局限性,包括与因果关系、混杂因素、数据质量、普遍性、反应偏差和多重共线性有关的问题。总之,这项研究为旨在加强疫苗接种活动和政策的政策制定者和公共卫生从业人员提供了宝贵的见解。
{"title":"Exploring the Impact of Socio-Demographic, Health, and Political Factors on COVID-19 Vaccination Attitudes","authors":"MD. Ekramul Islam Novel, ✉. M. Sarkar, Aisharyja Roy Puja","doi":"10.32996/jmhs.2024.5.1.8","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.8","url":null,"abstract":"This study examines the influence of socio-demographic, health, and political factors on attitudes towards COVID-19 vaccination during 2021-2022. Utilizing data from the General Social Survey (GSS), the research explores the relationships between COVID-19 vaccination status and variables such as confidence in medicine, political views, general health condition, income, education level, and marital status. The analysis employs logistic regression models and Chi-Square tests to assess these relationships. Key findings indicate that higher income and education levels, as well as more liberal political views, are positively associated with vaccination uptake. In contrast, marital status presents a more complex picture, suggesting further exploration is needed. The study highlights the multifaceted nature of vaccination decisions and underscores the importance of tailored public health strategies that address the specific needs and concerns of different demographic groups. The research also acknowledges challenges and limitations, including issues related to causality, confounding factors, data quality, generalizability, response bias, and multicollinearity. Overall, the study contributes valuable insights for policymakers and public health practitioners aiming to enhance vaccination campaigns and policies.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Research Status of Traditional Chinese Medicine Pension Industry Based on Bibliometrics 基于文献计量学的中药养老产业研究现状分析
Pub Date : 2024-03-09 DOI: 10.32996/jmhs.2024.5.1.7
Shiqing Li
At present, the problem of population aging in China is becoming increasingly prominent, and the combination of traditional Chinese medicine and elderly care is becoming a hot topic. In this paper, VOSviewer was used to statistically and visually analyze the literature related to traditional Chinese medicine pension in CNKI database from 2013 to 2023. Firstly, we collected and sorted out the research literature on the Chinese medicine pension industry in recent years, and then used bibliometric methods to quantitatively analyze the quantity, quality and research fields of the literature. The study found that the number of research literature on the elderly care industry of traditional Chinese medicine has increased year by year, the research quality has been continuously improved, and the research field has gradually expanded. At the same time, we also found that the research hotspots of traditional Chinese medicine for the elderly care industry are mainly focused on elderly care services, traditional Chinese medicine health preservation, rehabilitation treatment, etc (Ge & Xu, 2023). In addition, this paper also puts forward the shortcomings and development directions of the research on the Chinese medicine pension industry in China and hopes that this study can provide useful reference and guidance for the development of the Chinese medicine pension industry. Based on the China National Knowledge Infrastructure (CNKI) database as the main data source, this paper uses the topic search method in advanced search to search the CNKI database, and confirms that “Chinese medicine for the elderly” is used to read a large number of literature and understand the health care of traditional Chinese medicineAs the theme, the document format was set to see the full text only and Chinese and English extensions, the search time range was set from January 1th, 2013 to December 31th, 2023, the document type was set to academic journals, and the journal source category was set to all journals, a total of 149 articles were obtained, excluding news, publicity, interviews, correspondence and other literature that did not meet the research theme, and finally a total of 149 articles were obtained by manual screening 126 articles in Chinese. VOSviewer is an open-source network analysis tool, mainly used for scientific literature analysis, which can help users carry out visual analysis and network construction and is suitable for analyzing the research status of a certain field. In this paper, the VOSviewer visual analysis tool was used to process and analyze the literature data of 126 academic journals included in CNKI from 2013 to 2023, and the knowledge map of Chinese medicine pension in China was drawn, so as to visually analyze the author cooperation, hot topics and cutting-edge trends of Chinese medicine pension research in China.
当前,我国人口老龄化问题日益突出,中医药与养老相结合正成为热门话题。本文利用 VOSviewer 对 CNKI 数据库中 2013 年至 2023 年中医药养老相关文献进行统计和可视化分析。首先收集整理了近年来有关中医药养老产业的研究文献,然后采用文献计量学方法对文献的数量、质量和研究领域进行了定量分析。研究发现,有关中医药养老产业的研究文献数量逐年增加,研究质量不断提高,研究领域逐步扩大。同时,我们还发现中医药养老产业的研究热点主要集中在养老服务、中医药养生、康复治疗等方面(葛旭,2023)。此外,本文还提出了我国中医药养老产业研究的不足和发展方向,希望本研究能为中医药养老产业的发展提供有益的借鉴和指导。本文以中国国家知识基础设施(CNKI)数据库为主要数据源,采用高级检索中的主题检索法对 CNKI 数据库进行检索,确认以 "中医药养老 "为主题阅读了大量文献,了解了中医药的养生保健情况,文献格式设置为只看全文和中英文扩展、检索时间范围设置为2013年1月1日至2023年12月31日,文献类型设置为学术期刊,期刊来源类别设置为所有期刊,共获得149篇文献,剔除新闻、宣传、访谈、通信等不符合研究主题的文献,最终通过人工筛选获得中文文献126篇,共计149篇。VOSviewer是一款开源的网络分析工具,主要用于科学文献分析,可以帮助用户进行可视化分析和网络构建,适用于分析某一领域的研究现状。本文利用VOSviewer可视化分析工具对CNKI收录的126种学术期刊2013-2023年的文献数据进行处理分析,绘制了中国中医药养老知识图谱,从而直观地分析了中国中医药养老研究的作者合作、热点话题和前沿趋势。
{"title":"Analysis of the Research Status of Traditional Chinese Medicine Pension Industry Based on Bibliometrics","authors":"Shiqing Li","doi":"10.32996/jmhs.2024.5.1.7","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.7","url":null,"abstract":"At present, the problem of population aging in China is becoming increasingly prominent, and the combination of traditional Chinese medicine and elderly care is becoming a hot topic. In this paper, VOSviewer was used to statistically and visually analyze the literature related to traditional Chinese medicine pension in CNKI database from 2013 to 2023. Firstly, we collected and sorted out the research literature on the Chinese medicine pension industry in recent years, and then used bibliometric methods to quantitatively analyze the quantity, quality and research fields of the literature. The study found that the number of research literature on the elderly care industry of traditional Chinese medicine has increased year by year, the research quality has been continuously improved, and the research field has gradually expanded. At the same time, we also found that the research hotspots of traditional Chinese medicine for the elderly care industry are mainly focused on elderly care services, traditional Chinese medicine health preservation, rehabilitation treatment, etc (Ge & Xu, 2023). In addition, this paper also puts forward the shortcomings and development directions of the research on the Chinese medicine pension industry in China and hopes that this study can provide useful reference and guidance for the development of the Chinese medicine pension industry. Based on the China National Knowledge Infrastructure (CNKI) database as the main data source, this paper uses the topic search method in advanced search to search the CNKI database, and confirms that “Chinese medicine for the elderly” is used to read a large number of literature and understand the health care of traditional Chinese medicineAs the theme, the document format was set to see the full text only and Chinese and English extensions, the search time range was set from January 1th, 2013 to December 31th, 2023, the document type was set to academic journals, and the journal source category was set to all journals, a total of 149 articles were obtained, excluding news, publicity, interviews, correspondence and other literature that did not meet the research theme, and finally a total of 149 articles were obtained by manual screening 126 articles in Chinese. VOSviewer is an open-source network analysis tool, mainly used for scientific literature analysis, which can help users carry out visual analysis and network construction and is suitable for analyzing the research status of a certain field. In this paper, the VOSviewer visual analysis tool was used to process and analyze the literature data of 126 academic journals included in CNKI from 2013 to 2023, and the knowledge map of Chinese medicine pension in China was drawn, so as to visually analyze the author cooperation, hot topics and cutting-edge trends of Chinese medicine pension research in China.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"230 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obstetric Violence and its Impact on the Mental Well-being of Ecuadorian women: A Quantitative Approach 产科暴力及其对厄瓜多尔妇女心理健康的影响:定量方法
Pub Date : 2024-01-13 DOI: 10.32996/jmhs.2024.5.1.4
Paola Salazar-Vélez, Melissa Anchundia-Chávez, Karla Benítez-Herrera, Gabriel Solórzano-García
Obstetric violence refers to certain practices and behaviors carried out by health professionals towards women that belittle, violate and oppress them during pregnancy, childbirth and puerperium, whether in public or private settings. This type of violence is interpreted as a form of gender discrimination and represents a violation of human rights that has a direct impact on women's mental well-being. It manifests itself mainly as an inequality of power between healthcare professionals and pregnant women, whether during childbirth or the puerperium. The World Health Organization has stressed the importance of eliminating these harmful medical practices, urging medical personnel to react appropriately through dialogue and support for pregnant women. A nationally representative sample of women aged 12 years and older from the 2018 National Health and Nutrition Survey was used. Multicollinearity tests were used to avoid redundant information in the models. Next, we used factor analysis to generate an index of obstetric violence and performed linear regressions to observe the correlation between obstetric violence and mental well-being of women in our sample. Finally, we addressed the heterogeneity observed in the proposed relationship by using quantile regression techniques to disentangle the heterogeneous relationship in the distribution of mental well-being and obtain correlation coefficients, with their 95% confidence intervals (95% CI). Based on our findings, we highlight the urgent need to raise awareness and sensitize health professionals about this specific problem, since our main result indicates that there is a misleading correlation between obstetric violence and women's mental well-being. It is crucial to modify those health practices that violate women's rights. Another significant measure to improve the current situation would be the implementation of programs that give visibility to gender violence in the health sector, as well as the promotion of research focused on obstetric violence and the implementation of interventions that strengthen the autonomy of users.
产科暴力是指在怀孕、分娩和产褥期,无论是在公共场所还是在私人场所,医护人员对妇女实施的某些轻视、侵犯和压迫的做法和行为。这种暴力被解释为一种性别歧视,是对人权的侵犯,直接影响到妇女的精神健康。无论是在分娩期间还是在产褥期,它主要表现为医护人员与孕妇之间的权力不平等。世界卫生组织强调了消除这些有害医疗行为的重要性,敦促医务人员通过对话和对孕妇的支持做出适当反应。研究采用了 2018 年全国健康与营养调查中具有全国代表性的 12 岁及以上女性样本。我们使用了多重共线性测试,以避免模型中出现冗余信息。接下来,我们使用因子分析生成了产科暴力指数,并进行了线性回归,以观察样本中妇女的产科暴力与心理健康之间的相关性。最后,我们利用量子回归技术来分解心理健康分布中的异质性关系,并获得相关系数及其 95% 置信区间 (95%CI),从而解决了所提出的关系中观察到的异质性问题。根据我们的研究结果,我们强调迫切需要提高医疗专业人员对这一特殊问题的认识和敏感性,因为我们的主要结果表明,产科暴力与妇女的心理健康之间存在误导性的相关性。修改那些侵犯妇女权利的保健做法至关重要。改善目前状况的另一项重要措施是实施各种方案,提高卫生部门对性别暴力问题的关注度,以及促进以产科暴力为重点的研究和实施加强用户自主权的干预措施。
{"title":"Obstetric Violence and its Impact on the Mental Well-being of Ecuadorian women: A Quantitative Approach","authors":"Paola Salazar-Vélez, Melissa Anchundia-Chávez, Karla Benítez-Herrera, Gabriel Solórzano-García","doi":"10.32996/jmhs.2024.5.1.4","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.4","url":null,"abstract":"Obstetric violence refers to certain practices and behaviors carried out by health professionals towards women that belittle, violate and oppress them during pregnancy, childbirth and puerperium, whether in public or private settings. This type of violence is interpreted as a form of gender discrimination and represents a violation of human rights that has a direct impact on women's mental well-being. It manifests itself mainly as an inequality of power between healthcare professionals and pregnant women, whether during childbirth or the puerperium. The World Health Organization has stressed the importance of eliminating these harmful medical practices, urging medical personnel to react appropriately through dialogue and support for pregnant women. A nationally representative sample of women aged 12 years and older from the 2018 National Health and Nutrition Survey was used. Multicollinearity tests were used to avoid redundant information in the models. Next, we used factor analysis to generate an index of obstetric violence and performed linear regressions to observe the correlation between obstetric violence and mental well-being of women in our sample. Finally, we addressed the heterogeneity observed in the proposed relationship by using quantile regression techniques to disentangle the heterogeneous relationship in the distribution of mental well-being and obtain correlation coefficients, with their 95% confidence intervals (95% CI). Based on our findings, we highlight the urgent need to raise awareness and sensitize health professionals about this specific problem, since our main result indicates that there is a misleading correlation between obstetric violence and women's mental well-being. It is crucial to modify those health practices that violate women's rights. Another significant measure to improve the current situation would be the implementation of programs that give visibility to gender violence in the health sector, as well as the promotion of research focused on obstetric violence and the implementation of interventions that strengthen the autonomy of users.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"31 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139530711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myositis: A Comeback Complication of Viral Endemics 肌炎:病毒性地方病卷土重来的并发症
Pub Date : 2024-01-11 DOI: 10.32996/jmhs.2024.5.1.3
Ali Haider
Acute benign childhood myositis (ABCM) is an uncommon presentation of viral upper respiratory tract infection. Multiple etiologies exist, with the common association of influenzas A and B. The patient usually presents with lower limb pain with associated gait abnormalities in much more severe cases. The diagnosis is made through certain laboratory investigations, with an important aspect of excluding more serious differential diagnoses. This case report follows a 6-year-old male presenting with a complaint of bilateral calf pain and weakness, The Patient tested positive for influenza A leading to the diagnosis of ABCM.
急性良性儿童肌炎(ABCM)是病毒性上呼吸道感染的一种不常见表现。患者通常表现为下肢疼痛,严重者伴有步态异常。诊断是通过某些实验室检查做出的,重要的是要排除更严重的鉴别诊断。本病例报告的患者是一名 6 岁的男性,主诉双侧小腿疼痛和无力,甲型流感检测呈阳性,因此被诊断为 ABCM。
{"title":"Myositis: A Comeback Complication of Viral Endemics","authors":"Ali Haider","doi":"10.32996/jmhs.2024.5.1.3","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.3","url":null,"abstract":"Acute benign childhood myositis (ABCM) is an uncommon presentation of viral upper respiratory tract infection. Multiple etiologies exist, with the common association of influenzas A and B. The patient usually presents with lower limb pain with associated gait abnormalities in much more severe cases. The diagnosis is made through certain laboratory investigations, with an important aspect of excluding more serious differential diagnoses. This case report follows a 6-year-old male presenting with a complaint of bilateral calf pain and weakness, The Patient tested positive for influenza A leading to the diagnosis of ABCM.","PeriodicalId":509795,"journal":{"name":"Journal of Medical and Health Studies","volume":"23 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139534402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Medical and Health Studies
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1