Pub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101674
Zara Manuelyan MD , Edward Butt MD, MPH , Sreeram Parupudi MD
Behçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from gastroenterology viewpoint.
{"title":"Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management","authors":"Zara Manuelyan MD , Edward Butt MD, MPH , Sreeram Parupudi MD","doi":"10.1016/j.disamonth.2023.101674","DOIUrl":"10.1016/j.disamonth.2023.101674","url":null,"abstract":"<div><p><span><span>Behçet's disease<span> (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the </span></span>GI tract<span><span>. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, </span>immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from </span></span>gastroenterology viewpoint.</p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139375962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101672
Samina Khan MD , Sneha Annie Sebastian MD , Mihirkumar P. Parmar MBBS , Nitin Ghadge MD , Inderbir Padda MD, MPH , Ahmed S. Keshta MD , Naofel Minhaz MD , Apurva Patel MD
Inflammatory bowel disease (IBD) is a group of chronic relapsing disorders, including Crohn's disease (CD) and ulcerative colitis (UC), which affects an increasing number of people worldwide. In the last few decades, the scientific world has witnessed many developments in IBD management by controlling debilitating symptoms and remaining in remission for more protracted periods. Even so, we still have a large population suffering from active IBD. An individual's quality of life (QoL) can be severely affected by IBD, like any other chronic illness. In this article, we have reviewed factors influencing the QoL in IBD patients, including chronic pain, diet, physical activity, and psychological factors like depression, anxiety, and stress symptoms. We also discussed the mechanisms of diet-microbial-immune system interaction, currently available dietary therapies for active CD and UC, and early psycho-social interventions that can reduce the disease burden and improve QoL in IBD patients.
炎症性肠病（IBD）是一组慢性复发性疾病，包括克罗恩病（CD）和溃疡性结肠炎（UC），影响着全世界越来越多的人。在过去的几十年里，科学界见证了 IBD 治疗的许多进展，控制了使人衰弱的症状，并能在更长的时间内保持缓解。即便如此，我们仍然有大量的 IBD 患者。与其他慢性疾病一样，IBD 也会严重影响个人的生活质量（QoL）。在本文中，我们回顾了影响 IBD 患者生活质量的因素，包括慢性疼痛、饮食、体力活动以及抑郁、焦虑和压力症状等心理因素。我们还讨论了饮食-微生物-免疫系统相互作用的机制、目前可用于活动性 CD 和 UC 的饮食疗法，以及可减轻疾病负担和改善 IBD 患者 QoL 的早期心理-社会干预措施。
{"title":"Factors influencing the quality of life in inflammatory bowel disease: A comprehensive review","authors":"Samina Khan MD , Sneha Annie Sebastian MD , Mihirkumar P. Parmar MBBS , Nitin Ghadge MD , Inderbir Padda MD, MPH , Ahmed S. Keshta MD , Naofel Minhaz MD , Apurva Patel MD","doi":"10.1016/j.disamonth.2023.101672","DOIUrl":"10.1016/j.disamonth.2023.101672","url":null,"abstract":"<div><p><span><span>Inflammatory bowel disease (IBD) is a group of chronic relapsing disorders, including Crohn's disease (CD) and </span>ulcerative colitis (UC), which affects an increasing number of people worldwide. In the last few decades, the scientific world has witnessed many developments in IBD management by controlling debilitating symptoms and remaining in remission for more protracted periods. Even so, we still have a large population suffering from active IBD. An individual's </span>quality of life<span> (QoL) can be severely affected by IBD, like any other chronic illness. In this article, we have reviewed factors influencing the QoL in IBD patients, including chronic pain, diet, physical activity, and psychological factors like depression, anxiety, and stress symptoms. We also discussed the mechanisms of diet-microbial-immune system interaction, currently available dietary therapies for active CD and UC, and early psycho-social interventions that can reduce the disease burden and improve QoL in IBD patients.</span></p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139027303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/S0011-5029(24)00007-5
{"title":"Information for Readers","authors":"","doi":"10.1016/S0011-5029(24)00007-5","DOIUrl":"https://doi.org/10.1016/S0011-5029(24)00007-5","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101629
Carlos Romero-Morales , Daniel López-López , Jaime Almazán-Polo , Sara Mogedano-Cruz , María Dolores Sosa-Reina , Guillermo García-Pérez-de-Sevilla , Sebastián Martín-Pérez , Ángel González-de-la-Flor
Musculoskeletal injuries in elite sports are ones of the most impact issue because their remarkable impact on performance caused by drastic absence of training and competition and a progressive deterioration in physical health, emotional and social athletes' dimensions. Also, the prevalence of epidemiologic research found an incidence of musculoskeletal disorders vary within sports and in elite athletes which is even higher as a consequence of higher demand physical performance. This way, the loss of physical performance due to an sport injury impacts not only the individual economic sphere of the professional but also that ofsports entities, reaching, according to some studies, a loss estimated in the range of 74.7 million pounds. Thus, the purpose of this article is to review and to provide an overview of the most common musculoskeletal injuries in elite sports precipitating factors, clinical presentation, evidence-based diagnostic evaluation, and treatment recommendations with a view to preventing medical conditions or musculoskeletal injuries that may alter performance and general health in the elite athletes.
{"title":"Prevalence, diagnosis and management of musculoskeletal disorders in elite athletes: A mini-review","authors":"Carlos Romero-Morales , Daniel López-López , Jaime Almazán-Polo , Sara Mogedano-Cruz , María Dolores Sosa-Reina , Guillermo García-Pérez-de-Sevilla , Sebastián Martín-Pérez , Ángel González-de-la-Flor","doi":"10.1016/j.disamonth.2023.101629","DOIUrl":"10.1016/j.disamonth.2023.101629","url":null,"abstract":"<div><p>Musculoskeletal injuries in elite sports are ones of the most impact issue because their remarkable impact on performance caused by drastic absence of training and competition and a progressive deterioration in physical health, emotional and social athletes' dimensions. Also, the prevalence of epidemiologic research found an incidence of musculoskeletal disorders vary within sports and in elite athletes which is even higher as a consequence of higher demand physical performance. This way, the loss of physical performance due to an sport injury impacts not only the individual economic sphere of the professional but also that ofsports entities, reaching, according to some studies, a loss estimated in the range of 74.7 million pounds. Thus, the purpose of this article is to review and to provide an overview of the most common musculoskeletal injuries in elite sports precipitating factors, clinical presentation, evidence-based diagnostic evaluation, and treatment recommendations with a view to preventing medical conditions or musculoskeletal injuries that may alter performance and general health in the elite athletes.</p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0011502923001098/pdfft?md5=6aa11ecdab79b39acbeb3ee5685e3750&pid=1-s2.0-S0011502923001098-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10272475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101673
Jerrold B. Leikin MD (Senior Editor)
{"title":"Forword for selected topics in pathology of the gastrointestinal tract","authors":"Jerrold B. Leikin MD (Senior Editor)","doi":"10.1016/j.disamonth.2023.101673","DOIUrl":"10.1016/j.disamonth.2023.101673","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139111337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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