{"title":"RE: Should we use rifampicin in periprosthetic joint infections caused by staphylococci when the implant has been exchanged? A multicenter observational cohort study by Kramer et al","authors":"Heime Rieber","doi":"10.1093/ofid/ofae074","DOIUrl":"https://doi.org/10.1093/ofid/ofae074","url":null,"abstract":"","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139790988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Things We Do for No Reason – Ordering Streptococcus pneumoniae Urinary Antigen in Patients with Community-Acquired Pneumonia","authors":"Matthew R Davis, E. McCreary, Alex M Trzebucki","doi":"10.1093/ofid/ofae089","DOIUrl":"https://doi.org/10.1093/ofid/ofae089","url":null,"abstract":"","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139791456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RE: Should we use rifampicin in periprosthetic joint infections caused by staphylococci when the implant has been exchanged? A multicenter observational cohort study by Kramer et al","authors":"Heime Rieber","doi":"10.1093/ofid/ofae074","DOIUrl":"https://doi.org/10.1093/ofid/ofae074","url":null,"abstract":"","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":"61 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139850690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kusejko, D. Neofytos, C. van Delden, H. Hirsch, Pascal Meylan, K. Boggian, Cédric Hirzel, C. Garzoni, D. Sidler, A. Schnyder, S. Schaub, D. Golshayan, Fadi Haidar, M. Bonani, R. Kouyos, N. J. Mueller, P. Schreiber, P. Amico, John-David Aubert, V. Banz, S. Beckmann, G. Beldi, C. Berger, E. Berishvili, A. Berzigotti, I. Binet, P. Bochud, S. Branca, H. Bucher, E. Catana, A. Cairoli, Y. Chalandon, S. de Geest, O. de Rougemont, S. de Seigneux, M. Dickenmann, J. Dreifuss, M. Duchosal, T. Fehr, S. Ferrari-Lacraz, C. Garzoni, D. Golshayan, N. Goossens, F. H. J. Halter, D. Heim, C. Hess, S. Hillinger, H. Hirsch, P. Hirt, G. Hofbauer, U. Huynh-Do, F. Immer, M. Koller, M. Laager, B. Laesser, F. Lamoth, R. Lehmann, A. Leichtle, O. Manuel, H. Marti, M. Martinelli, V. McLin, K. Mellac, A. Merçay, K. Mettler, A. Müller, N. J. Mueller, U. Müller-Arndt, B. Müllhaupt, M. Nägeli, G. Oldani, M. Pascual, J. Passweg, R. Pazeller, K. Posfay-Barbe, J. Rick, A. Rosselet, S. Rossi, S. Rothlin, F. Ruschitzka, T. Schachtner, U. S
Infectious diseases (ID) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney re-transplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression. We included adult patients with records on the f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients, and compared infection rates, causative pathogens and infection sites. Recurrent time to event analyses were performed for comparison of infection rates. A total of 59 patients with a median age of 47 years (range = 18 - 73) were included. Overall, 312 ID events in 52 patients occurred. In multivariable recurrent event modelling, the rate of ID events was significantly lower after re-K-Tx (HR = 0.70, p = 0.02). More bacterial (68.9% versus 60.4%) and fungal (4.0% versus 1.1%) infections were observed after f-K-Tx, but less viral infections (27.0% versus 38.5%) as compared to after re-K-Tx (p = 0.11). After f-K-Tx, urinary tract and gastrointestinal tract infections were more frequent; after re-K-Tx, respiratory tract and surgical site infections were more frequent (p < 0.001). Infectious disease events were less frequent after re-K-Tx. Affected sites differed significantly after f-K-Tx compared to after re-K-Tx.
{"title":"Do infectious diseases after kidney re-transplantation differ from those after first kidney transplantation?","authors":"K. Kusejko, D. Neofytos, C. van Delden, H. Hirsch, Pascal Meylan, K. Boggian, Cédric Hirzel, C. Garzoni, D. Sidler, A. Schnyder, S. Schaub, D. Golshayan, Fadi Haidar, M. Bonani, R. Kouyos, N. J. Mueller, P. Schreiber, P. Amico, John-David Aubert, V. Banz, S. Beckmann, G. Beldi, C. Berger, E. Berishvili, A. Berzigotti, I. Binet, P. Bochud, S. Branca, H. Bucher, E. Catana, A. Cairoli, Y. Chalandon, S. de Geest, O. de Rougemont, S. de Seigneux, M. Dickenmann, J. Dreifuss, M. Duchosal, T. Fehr, S. Ferrari-Lacraz, C. Garzoni, D. Golshayan, N. Goossens, F. H. J. Halter, D. Heim, C. Hess, S. Hillinger, H. Hirsch, P. Hirt, G. Hofbauer, U. Huynh-Do, F. Immer, M. Koller, M. Laager, B. Laesser, F. Lamoth, R. Lehmann, A. Leichtle, O. Manuel, H. Marti, M. Martinelli, V. McLin, K. Mellac, A. Merçay, K. Mettler, A. Müller, N. J. Mueller, U. Müller-Arndt, B. Müllhaupt, M. Nägeli, G. Oldani, M. Pascual, J. Passweg, R. Pazeller, K. Posfay-Barbe, J. Rick, A. Rosselet, S. Rossi, S. Rothlin, F. Ruschitzka, T. Schachtner, U. S","doi":"10.1093/ofid/ofae055","DOIUrl":"https://doi.org/10.1093/ofid/ofae055","url":null,"abstract":"\u0000 \u0000 \u0000 Infectious diseases (ID) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney re-transplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression.\u0000 \u0000 \u0000 \u0000 We included adult patients with records on the f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients, and compared infection rates, causative pathogens and infection sites. Recurrent time to event analyses were performed for comparison of infection rates.\u0000 \u0000 \u0000 \u0000 A total of 59 patients with a median age of 47 years (range = 18 - 73) were included. Overall, 312 ID events in 52 patients occurred. In multivariable recurrent event modelling, the rate of ID events was significantly lower after re-K-Tx (HR = 0.70, p = 0.02). More bacterial (68.9% versus 60.4%) and fungal (4.0% versus 1.1%) infections were observed after f-K-Tx, but less viral infections (27.0% versus 38.5%) as compared to after re-K-Tx (p = 0.11). After f-K-Tx, urinary tract and gastrointestinal tract infections were more frequent; after re-K-Tx, respiratory tract and surgical site infections were more frequent (p < 0.001).\u0000 \u0000 \u0000 \u0000 Infectious disease events were less frequent after re-K-Tx. Affected sites differed significantly after f-K-Tx compared to after re-K-Tx.\u0000","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139799168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kusejko, D. Neofytos, C. van Delden, H. Hirsch, Pascal Meylan, K. Boggian, Cédric Hirzel, C. Garzoni, D. Sidler, A. Schnyder, S. Schaub, D. Golshayan, Fadi Haidar, M. Bonani, R. Kouyos, N. J. Mueller, P. Schreiber, P. Amico, John-David Aubert, V. Banz, S. Beckmann, G. Beldi, C. Berger, E. Berishvili, A. Berzigotti, I. Binet, P. Bochud, S. Branca, H. Bucher, E. Catana, A. Cairoli, Y. Chalandon, S. de Geest, O. de Rougemont, S. de Seigneux, M. Dickenmann, J. Dreifuss, M. Duchosal, T. Fehr, S. Ferrari-Lacraz, C. Garzoni, D. Golshayan, N. Goossens, F. H. J. Halter, D. Heim, C. Hess, S. Hillinger, H. Hirsch, P. Hirt, G. Hofbauer, U. Huynh-Do, F. Immer, M. Koller, M. Laager, B. Laesser, F. Lamoth, R. Lehmann, A. Leichtle, O. Manuel, H. Marti, M. Martinelli, V. McLin, K. Mellac, A. Merçay, K. Mettler, A. Müller, N. J. Mueller, U. Müller-Arndt, B. Müllhaupt, M. Nägeli, G. Oldani, M. Pascual, J. Passweg, R. Pazeller, K. Posfay-Barbe, J. Rick, A. Rosselet, S. Rossi, S. Rothlin, F. Ruschitzka, T. Schachtner, U. S
Infectious diseases (ID) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney re-transplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression. We included adult patients with records on the f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients, and compared infection rates, causative pathogens and infection sites. Recurrent time to event analyses were performed for comparison of infection rates. A total of 59 patients with a median age of 47 years (range = 18 - 73) were included. Overall, 312 ID events in 52 patients occurred. In multivariable recurrent event modelling, the rate of ID events was significantly lower after re-K-Tx (HR = 0.70, p = 0.02). More bacterial (68.9% versus 60.4%) and fungal (4.0% versus 1.1%) infections were observed after f-K-Tx, but less viral infections (27.0% versus 38.5%) as compared to after re-K-Tx (p = 0.11). After f-K-Tx, urinary tract and gastrointestinal tract infections were more frequent; after re-K-Tx, respiratory tract and surgical site infections were more frequent (p < 0.001). Infectious disease events were less frequent after re-K-Tx. Affected sites differed significantly after f-K-Tx compared to after re-K-Tx.
{"title":"Do infectious diseases after kidney re-transplantation differ from those after first kidney transplantation?","authors":"K. Kusejko, D. Neofytos, C. van Delden, H. Hirsch, Pascal Meylan, K. Boggian, Cédric Hirzel, C. Garzoni, D. Sidler, A. Schnyder, S. Schaub, D. Golshayan, Fadi Haidar, M. Bonani, R. Kouyos, N. J. Mueller, P. Schreiber, P. Amico, John-David Aubert, V. Banz, S. Beckmann, G. Beldi, C. Berger, E. Berishvili, A. Berzigotti, I. Binet, P. Bochud, S. Branca, H. Bucher, E. Catana, A. Cairoli, Y. Chalandon, S. de Geest, O. de Rougemont, S. de Seigneux, M. Dickenmann, J. Dreifuss, M. Duchosal, T. Fehr, S. Ferrari-Lacraz, C. Garzoni, D. Golshayan, N. Goossens, F. H. J. Halter, D. Heim, C. Hess, S. Hillinger, H. Hirsch, P. Hirt, G. Hofbauer, U. Huynh-Do, F. Immer, M. Koller, M. Laager, B. Laesser, F. Lamoth, R. Lehmann, A. Leichtle, O. Manuel, H. Marti, M. Martinelli, V. McLin, K. Mellac, A. Merçay, K. Mettler, A. Müller, N. J. Mueller, U. Müller-Arndt, B. Müllhaupt, M. Nägeli, G. Oldani, M. Pascual, J. Passweg, R. Pazeller, K. Posfay-Barbe, J. Rick, A. Rosselet, S. Rossi, S. Rothlin, F. Ruschitzka, T. Schachtner, U. S","doi":"10.1093/ofid/ofae055","DOIUrl":"https://doi.org/10.1093/ofid/ofae055","url":null,"abstract":"\u0000 \u0000 \u0000 Infectious diseases (ID) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney re-transplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression.\u0000 \u0000 \u0000 \u0000 We included adult patients with records on the f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients, and compared infection rates, causative pathogens and infection sites. Recurrent time to event analyses were performed for comparison of infection rates.\u0000 \u0000 \u0000 \u0000 A total of 59 patients with a median age of 47 years (range = 18 - 73) were included. Overall, 312 ID events in 52 patients occurred. In multivariable recurrent event modelling, the rate of ID events was significantly lower after re-K-Tx (HR = 0.70, p = 0.02). More bacterial (68.9% versus 60.4%) and fungal (4.0% versus 1.1%) infections were observed after f-K-Tx, but less viral infections (27.0% versus 38.5%) as compared to after re-K-Tx (p = 0.11). After f-K-Tx, urinary tract and gastrointestinal tract infections were more frequent; after re-K-Tx, respiratory tract and surgical site infections were more frequent (p < 0.001).\u0000 \u0000 \u0000 \u0000 Infectious disease events were less frequent after re-K-Tx. Affected sites differed significantly after f-K-Tx compared to after re-K-Tx.\u0000","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":"124 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139858962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laboratory report of HIV-1 low-level viremia","authors":"H. Álvarez, J. Llibre","doi":"10.1093/ofid/ofad667","DOIUrl":"https://doi.org/10.1093/ofid/ofad667","url":null,"abstract":"","PeriodicalId":510506,"journal":{"name":"Open Forum Infectious Diseases","volume":"59 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139533627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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