Pub Date : 2024-05-01DOI: 10.1016/S0140-6736(24)00921-8
S. Coutts, Sandeep Ankolekar, R. Appireddy, J. Arenillas, Z. Assis, Peter Bailey, P. A. Barber, Rodrigo Bazan, Brian H. Buck, Ken S Butcher, Marie-Christine Camden, Bruce Campbell, L. Casaubon, L. Catanese, Kausik Chatterjee, Philip M C Choi, Brian Clarke, Dar Dowlatshahi, Julia Ferrari, Thalia S. Field, A. Ganesh, D. Ghia, Mayank Goyal, S. Greisenegger, O. Halse, MacKenzie Horn, Gary Hunter, O. Imoukhuede, Peter J Kelly, James Kennedy, C. Kenney, Timothy J Kleinig, K. Krishnan, Fabrico Lima, J. Mandzia, M. Marko, Sheila O Martins, G. Medvedev, B. Menon, S. Mishra, Carlos Molina, A. Moussaddy, K. Muir, Mark W. Parsons, Andrew M Penn, Arthur Pille, O. Pontes-Neto, Christine Roffe, Joaquin Serena, R. Simister, Nishita Singh, Neil Spratt, Daniel Strbian, C. H. Tham, M. Wiggam, David J Williams, M. Willmot, Teddy Wu, Amy Y X Yu, George Zachariah, A. Zafar, C. Zerna, Michael D. Hill, M. Salluzzi, Nicole Blenkin, Ashley Dueck, Craig Doram, Qiao Zhang, Karla J. Ryckborst, Shelly Bohn, Quentin Collier, Frances Ta
{"title":"Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial","authors":"S. Coutts, Sandeep Ankolekar, R. Appireddy, J. Arenillas, Z. Assis, Peter Bailey, P. A. Barber, Rodrigo Bazan, Brian H. Buck, Ken S Butcher, Marie-Christine Camden, Bruce Campbell, L. Casaubon, L. Catanese, Kausik Chatterjee, Philip M C Choi, Brian Clarke, Dar Dowlatshahi, Julia Ferrari, Thalia S. Field, A. Ganesh, D. Ghia, Mayank Goyal, S. Greisenegger, O. Halse, MacKenzie Horn, Gary Hunter, O. Imoukhuede, Peter J Kelly, James Kennedy, C. Kenney, Timothy J Kleinig, K. Krishnan, Fabrico Lima, J. Mandzia, M. Marko, Sheila O Martins, G. Medvedev, B. Menon, S. Mishra, Carlos Molina, A. Moussaddy, K. Muir, Mark W. Parsons, Andrew M Penn, Arthur Pille, O. Pontes-Neto, Christine Roffe, Joaquin Serena, R. Simister, Nishita Singh, Neil Spratt, Daniel Strbian, C. H. Tham, M. Wiggam, David J Williams, M. Willmot, Teddy Wu, Amy Y X Yu, George Zachariah, A. Zafar, C. Zerna, Michael D. Hill, M. Salluzzi, Nicole Blenkin, Ashley Dueck, Craig Doram, Qiao Zhang, Karla J. Ryckborst, Shelly Bohn, Quentin Collier, Frances Ta","doi":"10.1016/S0140-6736(24)00921-8","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)00921-8","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141055659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1016/S0140-6736(24)00549-X
C. Parker, H. Kynaston, Adrian D Cook, Noel W. Clarke, C. Catton, William R Cross, Peter M Petersen, R.A. Persad, Cheryl A Pugh, Fred Saad, J. Logue, Heather Payne, Lorna C Bower, Chris Brawley, Mary Rauchenberger, M. Barkati, D. Bottomley, Klaus Brasso, Hans T Chung, Peter W M Chung, Ruth Conroy, A. Falconer, Vicky Ford, Chee L Goh, Catherine M Heath, Nicholas D James, Charmaine Kim-Sing, Ravi Kodavatiganti, Shawn C Malone, Stephen L Morris, A. Nabid, A. Ong, R. Raman, Sree Rodda, P. Wells, J. Worlding, W. Parulekar, M. Parmar, M. Sydes, C. Amos, Katherine Beaney, Katharine Bellenger, Chris Brawley, Christina Chung, Adrian D Cook, A. Embleton, S. Forcat, Cindy Goldstein, Jenna Grabey, Dominic Hague, Anna A. Herasimtschuk, Zaheer Islam, G. Jovic, C. Maniatis, Lindsey Masters, Fatima Mohamed, Rachel Morgan, Claire Murphy, Dipa Noor, Max Parmar, Pauline Patterson, Holly Pickering, Cheryl Pugh, Mary Rauchenberger, Helena Ribeiro, Carol Roach, Fatimah Seray-Wurie, Preetha Shaji, Hannah Sims, Ben Spittle, M. S
{"title":"Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial","authors":"C. Parker, H. Kynaston, Adrian D Cook, Noel W. Clarke, C. Catton, William R Cross, Peter M Petersen, R.A. Persad, Cheryl A Pugh, Fred Saad, J. Logue, Heather Payne, Lorna C Bower, Chris Brawley, Mary Rauchenberger, M. Barkati, D. Bottomley, Klaus Brasso, Hans T Chung, Peter W M Chung, Ruth Conroy, A. Falconer, Vicky Ford, Chee L Goh, Catherine M Heath, Nicholas D James, Charmaine Kim-Sing, Ravi Kodavatiganti, Shawn C Malone, Stephen L Morris, A. Nabid, A. Ong, R. Raman, Sree Rodda, P. Wells, J. Worlding, W. Parulekar, M. Parmar, M. Sydes, C. Amos, Katherine Beaney, Katharine Bellenger, Chris Brawley, Christina Chung, Adrian D Cook, A. Embleton, S. Forcat, Cindy Goldstein, Jenna Grabey, Dominic Hague, Anna A. Herasimtschuk, Zaheer Islam, G. Jovic, C. Maniatis, Lindsey Masters, Fatima Mohamed, Rachel Morgan, Claire Murphy, Dipa Noor, Max Parmar, Pauline Patterson, Holly Pickering, Cheryl Pugh, Mary Rauchenberger, Helena Ribeiro, Carol Roach, Fatimah Seray-Wurie, Preetha Shaji, Hannah Sims, Ben Spittle, M. S","doi":"10.1016/S0140-6736(24)00549-X","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)00549-X","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1016/S0140-6736(24)01017-1
Dinesh C Sharma
{"title":"Contrasting health visions in the Indian election","authors":"Dinesh C Sharma","doi":"10.1016/S0140-6736(24)01017-1","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)01017-1","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141053270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-07DOI: 10.1016/S0140-6736(23)02630-2
R. Hinman, P. Campbell, Alexander J. Kimp, Trevor Russell, Nadine E Foster, J. Kasza, Anthony Harris, K. Bennell
{"title":"Telerehabilitation consultations with a physiotherapist for chronic knee pain versus in-person consultations in Australia: the PEAK non-inferiority randomised controlled trial","authors":"R. Hinman, P. Campbell, Alexander J. Kimp, Trevor Russell, Nadine E Foster, J. Kasza, Anthony Harris, K. Bennell","doi":"10.1016/S0140-6736(23)02630-2","DOIUrl":"https://doi.org/10.1016/S0140-6736(23)02630-2","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-07DOI: 10.1016/S0140-6736(24)00063-1
P. Lanzetta, J. Korobelnik, J. Heier, Sergio Leal, F. Holz, W. Clark, D. Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J. Berliner, Andrea Schulze, T. Schmelter, U. Schmidt-Ott, Xin Zhang, R. Vitti, Karen W Chu, Kim Reed, Rohini Rao, R. Bhore, Yenchieh Cheng, Wei Sun, Boaz Hirshberg, G. Yancopoulos, Tien Y Wong
{"title":"Intravitreal aflibercept 8 mg in neovascular age-related macular degeneration (PULSAR): 48-week results from a randomised, double-masked, non-inferiority, phase 3 trial","authors":"P. Lanzetta, J. Korobelnik, J. Heier, Sergio Leal, F. Holz, W. Clark, D. Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J. Berliner, Andrea Schulze, T. Schmelter, U. Schmidt-Ott, Xin Zhang, R. Vitti, Karen W Chu, Kim Reed, Rohini Rao, R. Bhore, Yenchieh Cheng, Wei Sun, Boaz Hirshberg, G. Yancopoulos, Tien Y Wong","doi":"10.1016/S0140-6736(24)00063-1","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)00063-1","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-07DOI: 10.1016/S0140-6736(24)00229-0
Emily Y Chew
{"title":"Increasing concentrations of intravitreal therapies for neovascular age-related macular degeneration","authors":"Emily Y Chew","doi":"10.1016/S0140-6736(24)00229-0","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)00229-0","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-07DOI: 10.1016/S0140-6736(23)02791-5
Sophie D Bennett, J. H. Cross, Kashfia Chowdhury, Tamsin Ford, Isobel Heyman, A. Coughtrey, Emma Dalrymple, Sarah Byford, Bruce Chorpita, Peter Fonagy, R. Moss‐Morris, Colin Reilly, Jonathan A Smith, Terence Stephenson, Sophia Varadkar, James Blackstone, Harriet L Quartly, Tyler Hughes, Amy Lewins, Elana Moore, F. Walji, A. Welch, Emily Whelan, Alice Zacharia, Anaïs D'Oelsnitz, Mariam Shah, Laila Xu, Aikaterini Vezyroglou, Kirsten Mitchell, I. Nizza, Poushali Ganguli, R. Shafran
{"title":"Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK","authors":"Sophie D Bennett, J. H. Cross, Kashfia Chowdhury, Tamsin Ford, Isobel Heyman, A. Coughtrey, Emma Dalrymple, Sarah Byford, Bruce Chorpita, Peter Fonagy, R. Moss‐Morris, Colin Reilly, Jonathan A Smith, Terence Stephenson, Sophia Varadkar, James Blackstone, Harriet L Quartly, Tyler Hughes, Amy Lewins, Elana Moore, F. Walji, A. Welch, Emily Whelan, Alice Zacharia, Anaïs D'Oelsnitz, Mariam Shah, Laila Xu, Aikaterini Vezyroglou, Kirsten Mitchell, I. Nizza, Poushali Ganguli, R. Shafran","doi":"10.1016/S0140-6736(23)02791-5","DOIUrl":"https://doi.org/10.1016/S0140-6736(23)02791-5","url":null,"abstract":"","PeriodicalId":510912,"journal":{"name":"The Lancet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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