Pub Date : 2025-07-01DOI: 10.1053/j.ro.2025.04.006
Mitchel Muhleman , Richard K.J. Brown , Ka Kit Wong , Ragheed Al-Dulaimi , Nicolaas I. Bohnen
{"title":"Central Nervous System Nuclear Imaging","authors":"Mitchel Muhleman , Richard K.J. Brown , Ka Kit Wong , Ragheed Al-Dulaimi , Nicolaas I. Bohnen","doi":"10.1053/j.ro.2025.04.006","DOIUrl":"10.1053/j.ro.2025.04.006","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 3","pages":"Pages 238-264"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1053/j.ro.2025.04.005
Ka Kit Wong , Eric Hu , Azadeh Akhavanallaf , Yuni K. Dewaraja , Molly E. Roseland
{"title":"Lutetium-177 Theranostics and Dosimetry for Neuroendocrine Neoplasms and Prostate Cancer","authors":"Ka Kit Wong , Eric Hu , Azadeh Akhavanallaf , Yuni K. Dewaraja , Molly E. Roseland","doi":"10.1053/j.ro.2025.04.005","DOIUrl":"10.1053/j.ro.2025.04.005","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 3","pages":"Pages 317-345"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1053/j.ro.2025.02.002
Molly E. Roseland , Michael C. Huarng
Despite growing clinical interest in targeted PET tracers, FDG remains a stalwart in PET imaging due to its widespread availability and applicability. Recent data support expanded clinical indications for FDG-PET in the evaluation of acutely ill patients. This review aims to summarize recent developments in PET imaging among acutely ill patients, emphasizing expanding benign indications. This review highlights updated guidelines and recent evidence regarding FDG-PET in the evaluation of infection, fever of unknown origin, vascular inflammation, and rheumatologic disorders. We underscore the results of recent studies published in the last 5 years from publication, primarily between 2019 and 2024. FDG-PET remains a cornerstone of PET imaging, and its value in benign and inflammatory conditions continues to grow. While FDG-PET is essential for outpatient oncology, it is increasingly used to image hospitalized patients, given its ability to diagnose and localize infection and inflammation.
{"title":"What's New in FDG-PET? Recent Advances in Imaging Hospitalized Patients and Infectious/Inflammatory Conditions","authors":"Molly E. Roseland , Michael C. Huarng","doi":"10.1053/j.ro.2025.02.002","DOIUrl":"10.1053/j.ro.2025.02.002","url":null,"abstract":"<div><div>Despite growing clinical interest in targeted PET tracers, FDG remains a stalwart in PET imaging due to its widespread availability and applicability. Recent data support expanded clinical indications for FDG-PET in the evaluation of acutely ill patients. This review aims to summarize recent developments in PET imaging among acutely ill patients, emphasizing expanding benign indications. This review highlights updated guidelines and recent evidence regarding FDG-PET in the evaluation of infection, fever of unknown origin, vascular inflammation, and rheumatologic disorders. We underscore the results of recent studies published in the last 5 years from publication, primarily between 2019 and 2024. FDG-PET remains a cornerstone of PET imaging, and its value in benign and inflammatory conditions continues to grow. While FDG-PET is essential for outpatient oncology, it is increasingly used to image hospitalized patients, given its ability to diagnose and localize infection and inflammation.</div></div>","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 3","pages":"Pages 288-299"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1053/j.ro.2025.02.005
Gbemiga G. Sofowora, Katarzyna Gil
{"title":"Imaging in the Diagnosis of Cardiac Amyloidosis","authors":"Gbemiga G. Sofowora, Katarzyna Gil","doi":"10.1053/j.ro.2025.02.005","DOIUrl":"10.1053/j.ro.2025.02.005","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 3","pages":"Pages 265-273"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1053/j.ro.2025.04.001
Lakshmi Madhusoodanan , Benjamin L. Viglianti , Peter J.H. Scott
{"title":"Incoming novel radiotracer development: Fibroblast activation protein inhibitors for cancer diagnosis and treatment","authors":"Lakshmi Madhusoodanan , Benjamin L. Viglianti , Peter J.H. Scott","doi":"10.1053/j.ro.2025.04.001","DOIUrl":"10.1053/j.ro.2025.04.001","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 3","pages":"Pages 346-354"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1053/j.ro.2025.02.001
Christopher M. Walker
{"title":"Letter From the Guest Editor: Diseases of the Mediastinum","authors":"Christopher M. Walker","doi":"10.1053/j.ro.2025.02.001","DOIUrl":"10.1053/j.ro.2025.02.001","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 2","pages":"Page 104"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1053/j.ro.2024.10.001
Cody L. Thornburgh , Jeffrey R. Kunin , Ravi Patel , Mohamed A. Ebada , Christopher M Walker
{"title":"Mediastinal Germ Cell Tumors: Update From the WHO Classification of Tumors: 5th Edition","authors":"Cody L. Thornburgh , Jeffrey R. Kunin , Ravi Patel , Mohamed A. Ebada , Christopher M Walker","doi":"10.1053/j.ro.2024.10.001","DOIUrl":"10.1053/j.ro.2024.10.001","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 2","pages":"Pages 212-220"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1053/j.ro.2025.01.005
Prachi Agarwal MD, MS
{"title":"Letter From the Editor: Navigating the Mediastinum","authors":"Prachi Agarwal MD, MS","doi":"10.1053/j.ro.2025.01.005","DOIUrl":"10.1053/j.ro.2025.01.005","url":null,"abstract":"","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 2","pages":"Page 103"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1053/j.ro.2025.02.007
Shambo Guha Roy , Subba R Digumarthy
Mediastinal and hilar lymphadenopathy is a frequent finding in thoracic imaging, necessitating thorough evaluation to distinguish between transient, reactive, malignant, and non-malignant causes. This review explores the anatomy, function, and drainage patterns of thoracic lymph nodes, including the International Association for the Study of Lung Cancer (IASLC) classification system, which standardizes lymph node stations for lung cancer staging and broader diagnostic applications. Imaging modalities such as chest radiography (CXR) and computed tomography (CT) play crucial roles in assessing lymphadenopathy, with CT being the preferred tool due to its ability to characterize size, shape, borders, density, and enhancement patterns. Specific imaging features, including nodal size thresholds, calcification patterns, necrosis, and distribution, help narrow differential diagnoses, distinguishing between malignant and benign conditions such as tuberculosis, sarcoidosis, lymphoma, and metastases. Additionally, the involvement of extra-mediastinal nodes can provide diagnostic clues to systemic diseases. A systematic imaging approach enhances diagnostic accuracy, guiding appropriate clinical management and tissue sampling when necessary.
{"title":"Imaging Evaluation of Mediastinal and Hilar Lymphadenopathy: Approach, Classification, and Differential Diagnosis","authors":"Shambo Guha Roy , Subba R Digumarthy","doi":"10.1053/j.ro.2025.02.007","DOIUrl":"10.1053/j.ro.2025.02.007","url":null,"abstract":"<div><div>Mediastinal and hilar lymphadenopathy is a frequent finding in thoracic imaging, necessitating thorough evaluation to distinguish between transient, reactive, malignant, and non-malignant causes. This review explores the anatomy, function, and drainage patterns of thoracic lymph nodes, including the International Association for the Study of Lung Cancer (IASLC) classification system, which standardizes lymph node stations for lung cancer staging and broader diagnostic applications. Imaging modalities such as chest radiography (CXR) and computed tomography (CT) play crucial roles in assessing lymphadenopathy, with CT being the preferred tool due to its ability to characterize size, shape, borders, density, and enhancement patterns. Specific imaging features, including nodal size thresholds, calcification patterns, necrosis, and distribution, help narrow differential diagnoses, distinguishing between malignant and benign conditions such as tuberculosis, sarcoidosis, lymphoma, and metastases. Additionally, the involvement of extra-mediastinal nodes can provide diagnostic clues to systemic diseases. A systematic imaging approach enhances diagnostic accuracy, guiding appropriate clinical management and tissue sampling when necessary.</div></div>","PeriodicalId":51151,"journal":{"name":"Seminars in Roentgenology","volume":"60 2","pages":"Pages 105-122"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}