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Study of toxic interaction between fumonisin-B1 and ochratoxin-A for certain serum biochemical parameters in Japanese quail. 伏马毒素- b1与赭曲霉毒素- a对鹌鹑血清生化指标的毒性相互作用研究。
Q4 Veterinary Pub Date : 2012-12-30 DOI: 10.13005/BPJ/365
M. A. Khan, A. Iqbal, A. Bhat, R. Asrani
A total of 300 one day old quail chicks (Coturnix coturnix japonica) were divided into 4 groups (3 replicates per teatment), viz. control (CX), fumonisin B1 (FX), ochratoxin A (OX) and combination (FO) containing 75 birds in each group. Birds in the control group (CX) were fed quail mash alone, where as birds in group FX were fed 200 ppm of fumonisin B1 (FB1) from Fusarium verticillioides culture material; group OX was fed 2 ppm of ochratoxin A from Aspergillus ochraceous NRRL-3174; and group FO was fed a combination of 200 ppm of FB1 and 2 ppm of OTA. Diets were fed from day 1 to 28 to study serum biochemistry. Birds in general showed anorexia, dullness, diarrhoea, depression in body weight, poor feathering and incoordinated movements. Significantly increased serum creatinine and uric acid values were observed in our study.
试验选用1日龄鹌鹑雏鸡300只,分为对照(CX)、伏马菌素B1 (FX)、赭曲霉毒素A (OX)和复方(FO) 4组,每组75只,每组3个重复。对照组(CX)单独饲喂鹌鹑醪,FX组(FB1)饲喂200 ppm的黄斑镰刀菌培养材料中的伏马菌素B1 (FB1);OX组饲喂2 ppm赭曲霉NRRL-3174产赭曲霉毒素A;FO组饲喂200 ppm FB1和2 ppm OTA的组合饲料。饲喂第1 ~ 28天,研究血清生化。鸟类普遍表现出厌食、迟钝、腹泻、体重下降、羽化不良和运动不协调。在我们的研究中观察到血清肌酐和尿酸值明显升高。
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Veterinary Practitioner
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