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Editorial: Moral distress and its variations 社论:道德困扰及其变化
Pub Date : 2024-03-23 DOI: 10.58616/001c.93000
David Ring
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引用次数: 0
Below Elbow Amputation Due to Ischemic Complications after Radial Artery Cannulation: A Case Report 桡动脉插管后因缺血并发症导致肘下截肢:病例报告
Pub Date : 2024-03-23 DOI: 10.58616/001c.92532
Nathan Sarli, Sonal Kumar, Kassem Ghayyad
The patient is a 57 year old male with peripheral vascular disease and a non-healing thumb wound. After radial artery catheterization (RAC), he developed pain and numbness in the radial-sided 3.5 fingers and pulse oximetry readings <80%. With a possible diagnosis of carpal tunnel syndrome due to increased pressure, the patient underwent a carpal tunnel release (CTR) one week after the catheterization and reported immediate pain relief. Unfortunately, his wound failed to heal, and his pain returned one week later. Another operation was performed to decompress the carpal tunnel; however, the pain worsened, and fingertip necrosis progressed, including the thumb, index, and middle fingers. An angiogram showed arterial calcifications, ruling out reperfusion of the hand. A trans-forearm amputation was performed. This case highlights overlapping symptoms of ischemia and median nerve compression as well as the risk of hand ischemia after RAC in those with circulatory compromise.
患者是一名 57 岁的男性,患有外周血管疾病,拇指伤口无法愈合。桡动脉导管术(RAC)后,他的桡侧 3.5 指出现疼痛和麻木,脉搏氧饱和度读数小于 80%。由于压力增加,患者可能被诊断为腕管综合征,因此在导管术后一周接受了腕管松解术(CTR),并报告疼痛立即缓解。不幸的是,他的伤口未能愈合,一周后疼痛再次出现。患者接受了另一次腕管减压手术,但疼痛加剧,指尖坏死也在发展,包括拇指、食指和中指。血管造影显示动脉钙化,排除了手部再灌注的可能性。患者接受了经前臂截肢手术。本病例强调了缺血和正中神经受压的重叠症状,以及循环系统受损者在接受 RAC 后手部缺血的风险。
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引用次数: 0
Recent developments on cells involved in bone repair and their potential clinical applications 参与骨修复的细胞及其潜在临床应用的最新进展
Pub Date : 2024-03-23 DOI: 10.58616/001c.90443
E. C. Rodríguez-Merchán
This review of the literature has summarized recent developments on cells implicated in the different phases of bone healing and their potential clinical applications including inflammatory phase (neutrophils, macrophages, mast cells), fibrovascular phase (endothelial cells and mesenchymal stem cells - MSCs), bone formation (osteoblasts, chondrocytes), and callus remodeling (osteoclasts). Some studies have confirmed the two well-known facts that alcohol intake and dexamethasone negatively affect bone healing. Other studies have shown that Aucubin, Bortezomib, and human umbilical cord MSCs (HUCMSCs)Wnt10b promote bone healing of bone fractures. However, more research is needed to confirm their actual utility in the clinical practice of bone fracture treatment.
这篇文献综述总结了与骨愈合不同阶段有关的细胞及其潜在临床应用的最新进展,包括炎症阶段(中性粒细胞、巨噬细胞、肥大细胞)、纤维血管阶段(内皮细胞和间充质干细胞)、骨形成(成骨细胞、软骨细胞)和胼胝体重塑(破骨细胞)。一些研究证实了两个众所周知的事实,即酒精摄入和地塞米松会对骨愈合产生负面影响。其他研究表明,澳库宾、硼替佐米和人脐带间充质干细胞(HUCMSCs)Wnt10b可促进骨折的骨愈合。然而,还需要更多的研究来证实它们在骨折治疗临床实践中的实际效用。
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引用次数: 0
Periarticular Injections with Liposomal Bupivacaine in Comparison with Traditional (Bupivacaine/Ropivacaine) Periarticular Injections in Total Hip Arthroplasty: A Systematic Review 在全髋关节置换术中使用脂质体布比卡因进行关节周围注射与传统(布比卡因/罗比卡因)关节周围注射的比较:系统回顾
Pub Date : 2024-03-23 DOI: 10.58616/001c.90487
Rahul Muchintala, Nathaniel Kern, Gaston Davis, Patrick Ioffreda, Santiago Rengifo, Mohammad Khak
This systematic review aims to comprehensively evaluate the current literature to determine whether local infiltration liposomal bupivacaine (LB) used in total hip arthroplasty (THA) results in reduced pain scores and opioid consumption compared to traditional local anesthetics. A systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using Ovid Medline, PubMed, Scopus, and ScienceDirect databases. Articles were screened independently by two investigators based on inclusion criteria of 1) prospective randomized control trials or retrospective cohort studies, 2) conducted after the 2015 Food and Drug Administration (FDA) expansion of LB indication to local surgical infiltration, 3) compared LB as a periarticular injection to other local anesthetics used as a periarticular injection, and 4) available in English. Primary outcomes of pain scores and opioid consumption were reported. Secondary outcomes of interest included mobility, length of stay, costs, incidence of adverse events, and readmission rates. Bupivacaine costs $3 per dose, while LB costs $334 per dose. A total of seven articles were identified with the inclusion criteria. Four studies concluded that LB improves patient outcomes of pain scores and opioid consumption in patients receiving THA. Three studies found no benefit to using LB compared to their controls. Four studies found no significant reduction in the length of stay between the groups. There were no reported differences in the incidence of adverse events or total costs between the two groups. There are minimal benefits of reduced pain scores or opioid consumption when using LB opioid-sparing protocols compared to current protocols for patients undergoing THA. III
本系统性综述旨在全面评估现有文献,以确定与传统局麻药相比,在全髋关节置换术(THA)中使用局部浸润脂质体布比卡因(LB)是否会降低疼痛评分和阿片类药物的用量。根据系统综述和元分析首选报告项目(PRISMA)指南,我们使用 Ovid Medline、PubMed、Scopus 和 ScienceDirect 数据库进行了系统综述。文章由两名研究者根据以下纳入标准进行独立筛选:1)前瞻性随机对照试验或回顾性队列研究;2)在 2015 年美国食品药品管理局(FDA)将枸橼酸适应症扩展至局部手术浸润后进行;3)将枸橼酸作为关节周围注射剂与其他作为关节周围注射剂的局麻药进行比较;4)以英语提供。报告的主要结果包括疼痛评分和阿片类药物消耗量。次要结果包括活动能力、住院时间、费用、不良事件发生率和再入院率。布比卡因每剂成本为 3 美元,而 LB 每剂成本为 334 美元。共有七篇文章符合纳入标准。四项研究得出结论,LB 可改善 THA 患者的疼痛评分和阿片类药物消耗量。三项研究发现,与对照组相比,使用枸橼酸盐没有益处。四项研究发现两组患者的住院时间没有明显缩短。据报道,两组患者的不良事件发生率或总费用没有差异。对于接受 THA 手术的患者而言,与现行方案相比,使用枸橼酸保留阿片类药物方案在降低疼痛评分或阿片类药物用量方面的益处微乎其微。三
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引用次数: 0
Assessment of Surgical Training Modality Efficacy in Medical Students – A Comparison of Surgical Simulation, Video Demonstration, and Live Instruction 医科学生手术培训模式效果评估--手术模拟、视频演示和现场教学的比较
Pub Date : 2024-03-23 DOI: 10.58616/001c.88828
Payton M. Boere, Levi J. Buchan, Kerri-Anne Ciesielka, Jacob E. Tulipan, Michael Rivlin, Asif M. Ilyas
Surgical simulation is a growing form of education in medical training, but it remains unclear how simulation compares to traditional lecture or apprenticeship models of teaching when translating procedural knowledge to surgical performance. This study aimed to assess the effectiveness of translating procedural knowledge to surgical skill when trained by the surgical simulation app “Touch Surgery (TS),” recorded video lecture, or in-person teaching of the trigger finger release (TFR) surgery. The study also aimed to identify the learners’ preferred teaching modality. Twenty-seven first- and second-year medical students were recruited to participate. They were randomly assigned to one of three cohorts (n=9) as designated by a different TFR surgery learning modality: surgical simulation through TS (cohort “SS”), video demonstration (cohort “VIDEO”), or live teaching by a board-certified orthopaedic hand surgeon (cohort “LIVE”). Each participant completed their modality three times. They then completed an assessment of the procedural steps before performing the TFR surgery on a cadaver. Outcome measures included procedural test scores and cadaveric performance, evaluated using a surgery-specific detailed checklist, a global rating scale (GRS) of soft surgical skills, and a pass/fail assessment. Participants graded their modality’s usefulness using a 5-point Likert scale. There was no statistically significant difference in TFR procedural assessment scores (P=0.123) or cadaveric surgical performance between groups when evaluated by the surgery-specific step checklist (P=0.549), GRS (P=0.567), and pass/fail assessment (P=0.874). Students in the LIVE cohort rated their modality as their first-choice training tool (P=0.009); however, those in the SS cohort rated their modality as easiest to use, follow, and understand (P=0.010). All educational modalities should be considered in surgical training. This study demonstrates that students can perform cognitively and technically similar learning from virtual or live formats; however, they preferred live teaching. III
手术模拟是医学培训中一种不断发展的教育形式,但在将手术知识转化为手术表现方面,模拟与传统的讲授或学徒制教学模式相比有何不同,目前仍不清楚。本研究旨在评估通过手术模拟应用程序 "触摸手术(Touch Surgery,TS)"、录制的视频讲座或扳机指松开(TFR)手术的面对面教学进行培训时,将手术知识转化为手术技能的效果。研究还旨在确定学习者偏好的教学模式。研究招募了 27 名一年级和二年级医学生参加。他们被随机分配到由不同 TFR 手术学习模式指定的三个组群(n=9)中的一个:通过 TS 进行手术模拟(组群 "SS")、视频演示(组群 "VIDEO")或由经认证的手部整形外科医生进行现场教学(组群 "LIVE")。每位参与者完成各自的模式三次。然后,在对尸体进行 TFR 手术之前,他们要完成程序步骤评估。结果测量包括程序测试得分和尸体表现,使用手术特定的详细核对表、软手术技能总体评分表(GRS)和通过/失败评估进行评估。参与者使用 5 点李克特量表对其模式的实用性进行评分。通过手术特定步骤核对表(P=0.549)、GRS(P=0.567)和及格/不及格评估(P=0.874)进行评估时,各组之间的 TFR 程序评估得分(P=0.123)或尸体手术表现无统计学差异。LIVE队列的学生将他们的模式评为首选培训工具(P=0.009);然而,SS队列的学生则将他们的模式评为最易于使用、遵循和理解(P=0.010)。在外科培训中应考虑所有的教育模式。本研究表明,学生可以通过虚拟或现场形式进行认知和技术上相似的学习,但他们更喜欢现场教学。三
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引用次数: 0
The Evolution & Outcomes of Total Wrist Arthroplasty: Current Concepts 全腕关节置换术的发展与成果:当前概念
Pub Date : 2024-03-23 DOI: 10.58616/001c.74943
Clay B. Townsend, Joseph Paladino, Asif M. Ilyas
Over the last several decades, total wrist arthroplasty design and outcomes have significantly improved. The development of modern wrist arthroplasty began in the 1960s with a silicone spacer implant, which has progressively evolved to the metal-on polyethylene modular implants utilized today. Modern implants have been shown to have high patient satisfaction and increased 5-10 year survivorship; however, the overall utilization of total wrist arthroplasty has decreased in the United States since 2001. This could be due to several reasons, including improved modern therapies for rheumatoid arthritis preventing end-stage wrist disease, reliable outcomes with arthrodesis, and the high complication and revision rates of early total wrist implants. This review will discuss the design evolution of total wrist implants, which can be divided into four distinct generations. This review also presents the most recent outcome, complication, and survivorship results for the modern 4th generation of total wrist implants.
在过去的几十年里,全腕关节置换术的设计和效果都有了显著的提高。现代腕关节置换术的发展始于 20 世纪 60 年代,当时使用的是硅胶垫片植入体,后来逐渐发展为现在使用的金属聚乙烯模块化植入体。现代植入物已被证明具有很高的患者满意度,并提高了 5-10 年的存活率;然而,自 2001 年以来,全腕关节置换术在美国的总体使用率有所下降。这可能有几个原因,包括类风湿性关节炎现代疗法的改进,防止了腕关节疾病的终末期,关节置换术的疗效可靠,以及早期全腕关节假体的并发症和翻修率较高。本综述将讨论全腕关节植入物的设计演变,可分为四代。本综述还将介绍现代第四代全腕关节植入物的最新结果、并发症和存活率。
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引用次数: 0
Minimally Invasive Bunion Surgery for Hallux Valgus: A surgical Technique 针对拇指外翻的微创拇外翻手术:手术技术
Pub Date : 2024-03-23 DOI: 10.58616/001c.82177
Erdi Özdemir, Michael Aynardi
Hallux valgus is one of the most common foot pathologies. More than a hundred procedures have been described in treating hallux valgus deformity. Minimally invasive (MIS) hallux valgus surgery has a growing interest among foot and ankle surgeons due to its potential advantages over open surgeries, including smaller incisions, less postoperative pain, and improved cosmetics. Although MIS bunion surgery has been described in the past, early techniques were complicated by inadequate or poor fixation and complications related to the devices used for osteotomy. Recent technological advances and improved surgical techniques have led to a reemergence of MIS hallux valgus correction. 3rd generation MIS techniques have demonstrated promising results in short and midterm follow-up clinical studies. In this technique report, we aimed to describe preoperative evaluation, surgical technique, and postoperative management of MIS hallux valgus surgery.
足外翻是最常见的足部病症之一。在治疗足外翻畸形方面,已有上百种手术方法。与开放式手术相比,微创(MIS)拇外翻手术具有切口小、术后疼痛轻、美观等潜在优势,因此越来越受到足踝外科医生的关注。虽然 MIS 拇趾外翻手术在过去已有描述,但早期的技术因固定不足或不佳以及与截骨装置有关的并发症而变得复杂。近年来,技术的进步和手术技巧的改进使得 MIS 拇趾外翻矫正术再次兴起。第三代 MIS 技术在短期和中期的临床随访研究中显示出了良好的效果。在这份技术报告中,我们旨在描述 MIS 外翻矫正手术的术前评估、手术技巧和术后管理。
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引用次数: 0
Arthroscopic Bankart versus Open Latarjet; Short-to-Mid-Term Outcomes of Recurrence and Patient-Reported Outcomes in Patients with Recurrent Anterior Shoulder Dislocation 关节镜下 Bankart 与开放式 Latarjet;复发性肩关节前脱位患者的中短期复发结果和患者自述结果
Pub Date : 2024-03-23 DOI: 10.58616/001c.90553
Kassem Ghayyad, Peyman Mirghaderi, Meysam Akbarzadeh, Maryam Salami, M. Ebrahimzadeh, Amir Kachooei
This retrospective comparative study compared the short to mid-term outcomes of arthroscopic Bankart repair and open Latarjet procedures in patients with recurrent anterior shoulder instability. Patients who underwent either arthroscopic Bankart repair or open Latarjet procedures between 2008 and 2020, with at least one year of follow-up, were included. Arthroscopic Bankart repairs were performed on shoulders with minimal glenoid bone loss (<15%), and the Latarjet procedure was performed if the preoperative computed tomography (CT) scan showed a 15% bone loss on the glenoid side or 30-40% humeral head bone loss. Their surgery results and patient-reported outcome measures (PROMs) were assessed using the Oxford Shoulder Score (OSS) and Shoulder Pain and Disability Index (SPADI). 133 patients were analyzed in Latarjet (n = 67) and Bankart groups (n = 66). Before surgery, the two groups of patients were similar regarding surgery side, hand dominance, education level, occupation difficulty level, and smoking (P>0.05). However, Latarjet’s patients were younger (32 vs. 35, P=0.04), had a higher proportion of males (96% vs. 82%, P=0.01), and had a significantly shorter follow-up period (3.2 vs. 6.4 years, P<0.001) than the Bankart group. There was no significant difference between the Latarjet and Bankart groups regarding the follow-up’s OSS score (37 vs. 36; P=0.94) and SPADI score (22 vs. 24, P=0.80). Dislocation was observed in only one patient (1.5%) in the Latarjet group (P=1.0). Subluxation was observed in 5 patients (7.5%) of the Latarjet group and three patients (4.5%) of the Bankart group (P=0.4). The overall instability rate was similar (P>0.05). Our findings suggest that both arthroscopic Bankart repair and open Latarjet are reliable techniques in short to mid-term follow-up based on the glenoid bone loss cut-off of 15%. Therapeutic Level III
这项回顾性比较研究比较了关节镜下Bankart修复术和开放式Latarjet手术对复发性肩关节前方不稳定患者的中短期疗效。研究纳入了2008年至2020年间接受关节镜下Bankart修复术或开放式Latarjet手术的患者,这些患者至少接受了一年的随访。接受关节镜Bankart修复术的患者肩关节盂骨损失极小(0.05)。然而,Latarjet 的患者更年轻(32 岁对 35 岁,P=0.04),男性比例更高(96% 对 82%,P=0.01),随访时间明显更短(3.2 年对 6.4 年,P0.05)。我们的研究结果表明,在中短期随访中,关节镜下Bankart修复术和开放式Latarjet都是可靠的技术,以盂骨丢失15%为临界值。三级治疗
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引用次数: 0
Closed Midsubstance Rupture of the Biceps Brachii and Brachialis: A Case Report 闭合性肱二头肌和肱肌中间断裂:病例报告
Pub Date : 2024-03-23 DOI: 10.58616/001c.92563
Lilah Fones, Daniel Nemrov, Rick Tosti
Closed rupture of the biceps brachii muscle belly should be considered in patients who experience arm pain and weakness after a forceful extension of the elbow against a fixed point of compression in the mid-arm. A delayed or missed diagnosis may portend inferior outcomes. Magnetic resonance imaging (MRI) can confirm the diagnosis but may not fully define the lesion. Therefore, the treating physician should be fully prepared to encounter a greater magnitude of muscular injury than that defined by the MRI. In young, active patients, early surgical repair can be considered to optimize the strength and cosmetic appearance of the limb. The repair technique should consist of a self-grasping suture technique, which may need to be augmented by fascial flaps or allograft tissue.
肱二头肌肌腹闭合性断裂的患者在用力伸展肘部以对抗手臂中部的固定压迫点后,如果出现手臂疼痛和无力,则应考虑肱二头肌肌腹闭合性断裂。延误或漏诊可能预示着较差的治疗效果。磁共振成像(MRI)可以确诊,但可能无法完全确定病变部位。因此,治疗医生应做好充分准备,以应对比核磁共振成像确定的更严重的肌肉损伤。对于年轻、活跃的患者,可以考虑尽早进行手术修复,以优化肢体的力量和外观。修复技术应包括自抓缝合技术,可能需要使用筋膜瓣或同种异体组织进行增强。
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引用次数: 0
Use of Nerve Wraps in the Upper Extremity 上肢神经包裹的使用
Pub Date : 2024-03-23 DOI: 10.58616/001c.90454
Lilah Fones, Maura DePascal, Asif M. Ilyas
Nerve wraps have been used to potentially decrease perineural scarring and to create a local environment conducive to nerve healing, but no consensus exists on the indications for their use. The primary purpose of this study is to assess the operative indications for using the porcine extracellular matrix (PEM) nerve wrap in the upper extremities at a single center. A retrospective review of all patients that underwent PEM nerve wrapping over eight years by hand and upper extremity surgeons at a single orthopaedic practice yielded 104 procedures in 102 patients for analysis. The most common indication for surgery was for nerve wrapping of acute traumatic nerve injuries in 57 patients (55%), most frequently involving lacerations of the hand and forearm. Neurolysis and nerve wrapping for cases of chronic nerve compression with perineural scarring and fibrosis was the second most common indication, involving 41 patients (39%), most frequently for revision carpal and cubital tunnel release surgery. Six patients (5.8%) underwent mass removal or contracture release involving neurolysis with nerve wrapping. Three patients (2.9%) required reoperation, two in the acute group and one in the chronic group. However, there were no cases of nerve wrap rejection or extrusion. PEM nerve wrapping was used for various nerve injuries, from acute lacerations to recalcitrant chronic compression and mass excision. Further studies are necessary to determine whether patient outcomes are improved with the PEM nerve wrap. Level 4
神经包膜可减少神经周围瘢痕,并为神经愈合创造有利的局部环境,但在其使用适应症方面尚未达成共识。本研究的主要目的是评估一个中心在上肢使用猪细胞外基质(PEM)神经包膜的手术适应症。一家骨科医院的手外科医生和上肢外科医生对八年来接受猪细胞外基质(PEM)神经包裹术的所有患者进行了回顾性审查,共对102名患者的104例手术进行了分析。最常见的手术适应症是对 57 名患者(55%)的急性创伤性神经损伤进行神经包扎,其中最常见的是手部和前臂的撕裂伤。神经溶解术和神经包裹术用于治疗慢性神经压迫并伴有神经周围瘢痕和纤维化的病例是第二大最常见的适应症,涉及 41 名患者(39%),最常见的是腕管和肘管松解术的翻修手术。六名患者(5.8%)接受了肿块切除或挛缩松解术,包括神经溶解和神经包裹。三名患者(2.9%)需要再次手术,其中急性组两名,慢性组一名。不过,没有出现神经包膜排斥或挤出的病例。PEM神经包膜可用于各种神经损伤,从急性撕裂伤到顽固的慢性压迫和肿块切除。有必要进行进一步研究,以确定使用 PEM 神经包膜是否能改善患者的治疗效果。第四级
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引用次数: 0
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