As the science of Cosmetology evolves, facing increasingly high demands, the legislative framework related to cosmetic products in the European Union, which is extremely well organized, is constantly on the alert in order to ensure the protection of consumer health and the quality of the environment, but also the avoidance of fraud and financial loss. Challenges constantly arise for new opinions and regulations-amendments of legislative content, which can affect any point in the life cycle of a cosmetic product, from the conception of the initial idea, to the rejection of the product. Sometimes the trends that appear are harbingers of a later need that should be legally defined. For example, the tendency to reduce the use of microplastics, which was a wish-choice in the previous years, is now legally mandated. Therefore, sometimes legislative developments and trends in a field interact significantly. Some recent legislative-type events and the evolution of trends that appeared in the field of cosmetic products after the decisive experience of the pandemic that we recently experienced are selectively presented.
{"title":"Recent legislation and emerging trends in Cosmetology","authors":"Αnna Giannakoudaki","doi":"10.61873/xsff5760","DOIUrl":"https://doi.org/10.61873/xsff5760","url":null,"abstract":"As the science of Cosmetology evolves, facing increasingly high demands, the legislative framework related to cosmetic products in the European Union, which is extremely well organized, is constantly on the alert in order to ensure the protection of consumer health and the quality of the environment, but also the avoidance of fraud and financial loss. Challenges constantly arise for new opinions and regulations-amendments of legislative content, which can affect any point in the life cycle of a cosmetic product, from the conception of the initial idea, to the rejection of the product. Sometimes the trends that appear are harbingers of a later need that should be legally defined. For example, the tendency to reduce the use of microplastics, which was a wish-choice in the previous years, is now legally mandated. Therefore, sometimes legislative developments and trends in a field interact significantly. Some recent legislative-type events and the evolution of trends that appeared in the field of cosmetic products after the decisive experience of the pandemic that we recently experienced are selectively presented.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"27 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141102630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Letsiou, Foteini Βiskanaki, Dimitrios Chaniotis, A. Beloukas, V. Kefala
Oxidative stress is quite a significant form of attack on the skin as it is considered one of the most important factors that causes skin aging. The article attempts to understand oxidative stress in the skin through in vitro studies targeting various biochemical pathways. In addition, cosmetic ingredients are described with the aim of both preventing oxidative stress on the skin as well as maintaining and enhancing the essential biological functions of the skin.
{"title":"Oxidative stress and dermocosmetics","authors":"S. Letsiou, Foteini Βiskanaki, Dimitrios Chaniotis, A. Beloukas, V. Kefala","doi":"10.61873/esyc8850","DOIUrl":"https://doi.org/10.61873/esyc8850","url":null,"abstract":"Oxidative stress is quite a significant form of attack on the skin as it is considered one of the most important factors that causes skin aging. The article attempts to understand oxidative stress in the skin through in vitro studies targeting various biochemical pathways. In addition, cosmetic ingredients are described with the aim of both preventing oxidative stress on the skin as well as maintaining and enhancing the essential biological functions of the skin.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angeliki Tsouna, Spyridon Papageorgiou, P. Pavlou, Fotini Mellou, A. Varvaresou, Apostolos G. Papadopoulos, Anna Giannakoudaki
Cosmetic products whose ingredients and especially the active agents have a natural origin, are characterized as natural. Natural cosmetics may have plant (extracts, essential oils, active plant ingredients, etc.) animal, marine or mineral ingredients with the least and safest possible processing. In the present study, a toothpaste with ingredients of natural origin was developed. Research was conducted on the most suitable natural flavoring, natural sweetener. The physico-chemical stability, microbiological stability and the main organoleptic characteristics, such as texture, viscosity and taste, which are the main factors for the choice and acceptance of these products by consumers, were studied. Additionally, the efficacy of various natural antimicrobial agents, in terms of protection against microbial plaque, was studied using in vitro methods and compared with a synthetic-«conventional» commercial toothpaste and a placebo sample.
{"title":"Natural, Organic Cosmetics and New trends. Development of a Natural Toothpaste against plaque","authors":"Angeliki Tsouna, Spyridon Papageorgiou, P. Pavlou, Fotini Mellou, A. Varvaresou, Apostolos G. Papadopoulos, Anna Giannakoudaki","doi":"10.61873/zurk6707","DOIUrl":"https://doi.org/10.61873/zurk6707","url":null,"abstract":"Cosmetic products whose ingredients and especially the active agents have a natural origin, are characterized as natural. Natural cosmetics may have plant (extracts, essential oils, active plant ingredients, etc.) animal, marine or mineral ingredients with the least and safest possible processing. In the present study, a toothpaste with ingredients of natural origin was developed. Research was conducted on the most suitable natural flavoring, natural sweetener. The physico-chemical stability, microbiological stability and the main organoleptic characteristics, such as texture, viscosity and taste, which are the main factors for the choice and acceptance of these products by consumers, were studied. Additionally, the efficacy of various natural antimicrobial agents, in terms of protection against microbial plaque, was studied using in vitro methods and compared with a synthetic-«conventional» commercial toothpaste and a placebo sample.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"14 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Chaniotis, A. Beloukas, Anastasios D. Papanastasiou, S. Letsiou, V. Kefala, Foteini Biskanaki
The phenomenon of longevity and healthy aging as well as the factors that can slow down or even prevent the appearance of pathological conditions related to aging is a subject of interest in modern biology and medical research. In this context, a series of clinical and biochemical indicators are recorded and evaluated, as well as a wide variety of cellular aging biomarkers that include molecular signals and biomolecules at the proteomic, metabolomic, genomic and epigenetic level. The use of biomarkers to assess biological aging can help predict life expectancy and quality of life. The reliability of various biomarkers of aging should also be tested for validity against clinical markers of aging, such as frailty, loss of (physical) function, chronic diseases and disabilities.
{"title":"Βiomarkers of aging","authors":"Dimitrios Chaniotis, A. Beloukas, Anastasios D. Papanastasiou, S. Letsiou, V. Kefala, Foteini Biskanaki","doi":"10.61873/weju9663","DOIUrl":"https://doi.org/10.61873/weju9663","url":null,"abstract":"The phenomenon of longevity and healthy aging as well as the factors that can slow down or even prevent the appearance of pathological conditions related to aging is a subject of interest in modern biology and medical research. In this context, a series of clinical and biochemical indicators are recorded and evaluated, as well as a wide variety of cellular aging biomarkers that include molecular signals and biomolecules at the proteomic, metabolomic, genomic and epigenetic level. The use of biomarkers to assess biological aging can help predict life expectancy and quality of life. The reliability of various biomarkers of aging should also be tested for validity against clinical markers of aging, such as frailty, loss of (physical) function, chronic diseases and disabilities.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"48 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141102298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Semeli Evgenia Sklivanaki, Apostolos G. Papadopoulos, A. Varvaresou, Spyridon Papageorgiou
The phenomenon of longevity and healthy aging as well as the factors that can slow down or even prevent the appearance of pathological conditions related to aging is a subject of interest in modern biology and medical research. In this context, a series of clinical and biochemical indicators are recorded and evaluated, as well as a wide variety of cellular aging biomarkers that include molecular signals and biomolecules at the proteomic, metabolomic, genomic and epigenetic level. The use of biomarkers to assess biological aging can help predict life expectancy and quality of life. The reliability of various biomarkers of aging should also be tested for validity against clinical markers of aging, such as frailty, loss of (physical) function, chronic diseases and disabilities.
{"title":"Extraction methods of polysaccharides, peptides, pigments, polyphenols from red and brown algae and their use in the treatment of skin hyperpigmentation and wrinkling","authors":"Semeli Evgenia Sklivanaki, Apostolos G. Papadopoulos, A. Varvaresou, Spyridon Papageorgiou","doi":"10.61873/zvxj7867","DOIUrl":"https://doi.org/10.61873/zvxj7867","url":null,"abstract":"The phenomenon of longevity and healthy aging as well as the factors that can slow down or even prevent the appearance of pathological conditions related to aging is a subject of interest in modern biology and medical research. In this context, a series of clinical and biochemical indicators are recorded and evaluated, as well as a wide variety of cellular aging biomarkers that include molecular signals and biomolecules at the proteomic, metabolomic, genomic and epigenetic level. The use of biomarkers to assess biological aging can help predict life expectancy and quality of life. The reliability of various biomarkers of aging should also be tested for validity against clinical markers of aging, such as frailty, loss of (physical) function, chronic diseases and disabilities.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"4 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Foteini Biskanaki, A. Beloukas, S. Letsiou, Dimitrios Chaniotis, V. Kefala
A balanced microbiome protects against external environmental factors, strengthens the skin's defenses and slows the appearance of the signs of skin aging. In recent years, alternative treatments have been sought to treat various skin problems, through modification or supplementation of the microbiome, using prebiotics and probiotics. Cosmetics with probiotics and prebiotics are a rich source of proteins and vitamins and have been shown to strengthen the skin's proteome.
{"title":"The use of probiotics and prebiotics in the restoration of aesthetic problems. What is a proteome?","authors":"Foteini Biskanaki, A. Beloukas, S. Letsiou, Dimitrios Chaniotis, V. Kefala","doi":"10.61873/khit7849","DOIUrl":"https://doi.org/10.61873/khit7849","url":null,"abstract":"A balanced microbiome protects against external environmental factors, strengthens the skin's defenses and slows the appearance of the signs of skin aging. In recent years, alternative treatments have been sought to treat various skin problems, through modification or supplementation of the microbiome, using prebiotics and probiotics. Cosmetics with probiotics and prebiotics are a rich source of proteins and vitamins and have been shown to strengthen the skin's proteome.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"9 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vasileia Xagorari, Zoi Tiligada, P. Pavlou, Chalikias Miltiadis, Spyridon Papageorgiou, A. Varvaresou
With the increase in interest for natural innovative skin care products, an effort was made in our laboratory to study the beneficial effects of cannabinoids and prebiotics/probiotics on the skin. Through efficacy studies, the contribution of the specific active substances to improving the health and appearance of the skin was investigated. The present research offers important data creating new perspectives for the improvement of skin care with natural ingredients. The research was carried out on 13 healthy volunteers from the ages of 24 - 53. Two products (Cream and Serum) with the active substances under study and placebo ones were used. The cosmetic products were applied externally to the skin, twice a day for 30 days. The methods used were: a) self-assessment questionnaire, and b) non-intrusive biophysical parameters. Specifically, skin elasticity (Cutometer dual MPA 580), skin microtopography (Skin Visioscan VC 98), transepidermal water loss (MPA5-Tewameter) and hydration of the keratin layer (MPA5-Corneometer CM) were measured 825). Based on the findings, the main conclusions of the research are summarized, highlighting the effectiveness of the products in improving the quality of the skin.
{"title":"Efficacy study of facial products enriched with probiotics/prebiotics & cannabinoids","authors":"Vasileia Xagorari, Zoi Tiligada, P. Pavlou, Chalikias Miltiadis, Spyridon Papageorgiou, A. Varvaresou","doi":"10.61873/nlxe1894","DOIUrl":"https://doi.org/10.61873/nlxe1894","url":null,"abstract":"With the increase in interest for natural innovative skin care products, an effort was made in our laboratory to study the beneficial effects of cannabinoids and prebiotics/probiotics on the skin. Through efficacy studies, the contribution of the specific active substances to improving the health and appearance of the skin was investigated. The present research offers important data creating new perspectives for the improvement of skin care with natural ingredients. The research was carried out on 13 healthy volunteers from the ages of 24 - 53. Two products (Cream and Serum) with the active substances under study and placebo ones were used. The cosmetic products were applied externally to the skin, twice a day for 30 days. The methods used were: a) self-assessment questionnaire, and b) non-intrusive biophysical parameters. Specifically, skin elasticity (Cutometer dual MPA 580), skin microtopography (Skin Visioscan VC 98), transepidermal water loss (MPA5-Tewameter) and hydration of the keratin layer (MPA5-Corneometer CM) were measured 825). Based on the findings, the main conclusions of the research are summarized, highlighting the effectiveness of the products in improving the quality of the skin.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141098708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioanna Kourou, A. Varvaresou, Fotini Mellou, P. Pavlou, Spyridon Papageorgiou, Apostolos G. Papadopoulos
The aim of the present experimental study is the incorporation of an extract of the Porphyra Umbilicalis seaweed, which contains mycosporin derivatives (MAAs) in a sunscreen formulation, in combination with organic filters, in order to study its influence on the SPF and UVA PF. The results obtained from the in vitro SPF and UVA PF measurements as well as the physicochemical stability control of the new formulas, contribute to the effort for the partial replacement of organic sunscreen filters in sunscreen compositions.
{"title":"New technologies in sunscreen cosmetics","authors":"Ioanna Kourou, A. Varvaresou, Fotini Mellou, P. Pavlou, Spyridon Papageorgiou, Apostolos G. Papadopoulos","doi":"10.61873/jtje9844","DOIUrl":"https://doi.org/10.61873/jtje9844","url":null,"abstract":"The aim of the present experimental study is the incorporation of an extract of the Porphyra Umbilicalis seaweed, which contains mycosporin derivatives (MAAs) in a sunscreen formulation, in combination with organic filters, in order to study its influence on the SPF and UVA PF. The results obtained from the in vitro SPF and UVA PF measurements as well as the physicochemical stability control of the new formulas, contribute to the effort for the partial replacement of organic sunscreen filters in sunscreen compositions.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"47 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Kokrasvili, V. Harizopoulou, Angeliki Bolou, K. Gourounti
Preeclampsia is a hypertensive disease that occurs during pregnancy in 3 to 8% of pregnancies worldwide. This disease causes significant maternal and perinatal morbidity and mortality. This article attempts to understand the pathophysiological mechanism of preeclampsia, which appears to result from a complex interaction between maternal and fetal factors and affects multiple organ systems. A central role in pre-eclampsia appears to be abnormal placentation with subsequent excess of anti-angiogenic factors and malabsorption. Further studies are needed to elucidate the pathophysiology of preeclampsia to better understand the disease, more appropriate treatment, and reduce maternal and neonatal morbidity and mortality.
{"title":"Pathophysiology of Preeclampsia","authors":"Anna Kokrasvili, V. Harizopoulou, Angeliki Bolou, K. Gourounti","doi":"10.61873/cqzb7130","DOIUrl":"https://doi.org/10.61873/cqzb7130","url":null,"abstract":"Preeclampsia is a hypertensive disease that occurs during pregnancy in 3 to 8% of pregnancies worldwide. This disease causes significant maternal and perinatal morbidity and mortality. This article attempts to understand the pathophysiological mechanism of preeclampsia, which appears to result from a complex interaction between maternal and fetal factors and affects multiple organ systems. A central role in pre-eclampsia appears to be abnormal placentation with subsequent excess of anti-angiogenic factors and malabsorption. Further studies are needed to elucidate the pathophysiology of preeclampsia to better understand the disease, more appropriate treatment, and reduce maternal and neonatal morbidity and mortality.","PeriodicalId":516794,"journal":{"name":"Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition","volume":"17 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139640405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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