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Assessing knowledge, attitude and practice of community pharmacists on the pain management and implications in UAE children. 评估社区药剂师对阿联酋儿童疼痛管理的知识、态度和实践及其影响。
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-05-03 DOI: 10.18549/PharmPract.2022.2.2664
Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Maimona Jairoun, Amanj Kurdi, Brian Godman

Objective: There are concerns with the optimal management of pain in children, with sub-optimal management negatively impacting on physical, emotional social functioning, exacerbated by pain in children being multi-modal. Community pharmacists across countries play an important role in managing pain in patients including children's pain. Consequently, the objective of this study is to assess knowledge, attitudes and practices (KAP) of pain management in children among community pharmacists in UAE.

Methods: A cross-sectional study was conducted using a structured questionnaire that was developed and piloted. The final questionnaire, which comprised two parts, had acceptable validity and internal consistency.

Results: 867 out of 922 community pharmacists took part in UAE (94% response rate) and were visited by trained researchers. The most from independent pharmacies (53.9%) and having more than 10 years of experience (68.9%). The overall KAP score was 70%, with gender, pharmacy type, years of experience, educational level and position significantly associated with KAP. Encouraging knowledge areas included pain is one of the vital signs in children (88.6%), the intensity of pain should be rated by a pharmacist before discussing treatment options (92.2%) and the choice of treatment should depend on issues including intensity and duration (87.2%). Areas of concern included the contents of the WHO analgesic ladder (32.0%) and children may sleep in spite of severe pain (42.9%).

Conclusion: There were areas of good knowledge of pain management among community pharmacists in UAE. Areas of concern including knowledge of the WHO analgesic ladder need to be addressed as part of future educational input during training and post qualification.

目的:关注儿童疼痛的最佳管理,次优管理对儿童的身体、情感和社会功能产生负面影响,并因儿童疼痛的多模态而加剧。各国的社区药剂师在管理包括儿童疼痛在内的患者疼痛方面发挥着重要作用。因此,本研究的目的是评估阿联酋社区药剂师对儿童疼痛管理的知识、态度和实践(KAP)。方法:一项横断面研究是使用一个结构化的问卷调查,是开发和试点。最终问卷由两部分组成,效度和内部一致性可接受。结果:922名社区药剂师中有867名参加了阿联酋(94%的回复率),并由训练有素的研究人员进行了访问。在独立药房工作最多(53.9%),工作经验超过10年的占68.9%。KAP总分为70%,性别、药房类型、工作年限、学历、职位与KAP显著相关。鼓励知识领域包括疼痛是儿童的生命体征之一(88.6%),疼痛的强度应由药剂师在讨论治疗方案之前评估(92.2%),治疗的选择应取决于强度和持续时间(87.2%)。值得关注的领域包括WHO镇痛阶梯的内容(32.0%)和儿童可能在剧烈疼痛中入睡(42.9%)。结论:阿联酋社区药师对疼痛管理有较好的认识。需要将包括世卫组织镇痛阶梯知识在内的关注领域作为未来培训和岗位资格认证期间教育投入的一部分加以解决。
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引用次数: 2
Analysis of the clinical practice of the pharmacist in a community pharmacy: A Cross-sectional Study from Brazil. 社区药房药剂师的临床实践分析:巴西横断面研究。
IF 2.4 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-04-13 DOI: 10.18549/PharmPract.2022.2.2658
Marcos Felipe Rodrigues de Souza, Maria Pantoja Moreira de Sena, Camila Martins Oliveira, Clarisse Andrade Sales, Renato Bruno Cavalcante de Melo, Luann Wendel Pereira de Sena

Background: The pharmaceutical profession has experienced renewals over time. In community pharmacies, pharmaceutical services contribute to the public health system in Brazil. The development of these tasks, in collaboration with professionals from the multidisciplinary team, demonstrates the involvement with the well-being, health and improvement of the patient's life.

Objectives: This study aimed to identify the professional practice of pharmacists, their understandings and attitudes towards clinical practice in community pharmacies in northern Brazil.

Methods: This is a cross-sectional descriptive study, based on a questionnaire carried out with pharmacists for seven months in the municipality of Belém, in the state of Pará. Data were expressed using descriptive statistics and the results were shown as a percentage.

Results: 182 pharmacists participated. Females were predominant (80.2%) and the average age of participants was 34.2 years. 77.4% graduated from private institutions and 59.3% already have a specialization. 38.4% hold the position of technical director. 50.5% of respondents say that community pharmacies have a reserved place for service. The most used clinical services were pharmacotherapy review (89.5%), health education (60.9%), dispensing (34%), therapeutic monitoring (25.8%) and pharmacotherapeutic follow-up (4.9%). In the study, it was realized that community pharmacies should not be seen as a commercial place but rather as a health care facility.

Conclusions: Therefore, these establishments must adapt at a structural and professional level, to meet an increasingly growing demand of a population in need of services offered with quality health care.

背景:随着时间的推移,制药行业也经历了更新换代。在社区药房,药剂服务为巴西的公共卫生系统做出了贡献。通过与多学科团队的专业人员合作开展这些工作,表明了药剂师对患者福祉、健康和生活改善的参与:本研究旨在确定药剂师的专业实践、他们对巴西北部社区药房临床实践的理解和态度:这是一项横断面描述性研究,以帕拉州贝伦市药剂师为期七个月的问卷调查为基础。数据采用描述性统计,结果以百分比表示:182 名药剂师参加了调查。结果:182 名药剂师参加了调查,其中女性居多(80.2%),平均年龄为 34.2 岁。77.4% 毕业于私立院校,59.3% 已拥有一门专业。38.4% 的人担任技术主管职务。50.5%的受访者表示社区药房有专门的服务场所。使用最多的临床服务是药物治疗审查(89.5%)、健康教育(60.9%)、配药(34%)、治疗监测(25.8%)和药物治疗跟踪(4.9%)。研究结果表明,社区药房不应被视为商业场所,而应被视为医疗机构:因此,这些机构必须在结构和专业层面上进行调整,以满足人们日益增长的对优质医疗保健服务的需求。
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引用次数: 0
COVID-19 vaccination, do women suffer from more side effects than men? A retrospective cross-sectional study. COVID-19疫苗接种,女性是否比男性更容易产生副作用?回顾性横断面研究。
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-06-10 DOI: 10.18549/PharmPract.2022.2.2678
Harith Kh Al-Qazaz, Luma M Al-Obaidy, Heba M Attash

The vaccine was the only way to fight against Coronavirus-19 (COVID-19) from its statement as a pandemic till day. COVID-19 vaccines were approved by the world health organization (WHO) in December 2020. Despite a large number of studies regarding the efficacy and safety of COVID-19 vaccines, to our knowledge, there were limited studies that outlined the gender disparity towards COVID-19 vaccine adverse effects. This study aims to outline the variety of side effects among men and women after getting COVID-19 vaccines (either single or two doses). It is a cross-sectional study accomplished electronically from September to November 2021. The participants involved were 843 Health Care Workers (HCWs) from different cities in Iraq. The majority of respondents were females (664). Around 65% of males experienced adverse effects compared to 77% of females. A high frequency of severe pain was reported among females. Regarding dermatological reactions like swelling, redness and skin rash were also higher reported among female subjects. In addition to that, higher frequencies of moderate and severe systemic adverse effects and mild to moderate nausea was also reported more frequently among females. In terms of cardiopulmonary adverse effects, all the reported adverse effects were found more frequently among females. In conclusion, COVID-19 vaccines produced limited adverse effects and the majority of them were reported among women. This may be associated with hormonal and psychological factors related to them.

从冠状病毒19 (COVID-19)被宣布为大流行到今天,这种疫苗是对抗它的唯一方法。新冠肺炎疫苗于2020年12月获得世界卫生组织(世卫组织)批准。尽管有大量关于COVID-19疫苗有效性和安全性的研究,但据我们所知,很少有研究概述了COVID-19疫苗不良反应的性别差异。这项研究旨在概述男性和女性接种COVID-19疫苗(单剂或两剂)后的各种副作用。这是一项横断面研究,从2021年9月到11月通过电子方式完成。所涉及的参与者是来自伊拉克不同城市的843名卫生保健工作者。大多数受访者是女性(664人)。大约65%的男性出现了不良反应,而女性的这一比例为77%。据报道,女性中出现剧烈疼痛的频率很高。至于皮肤反应,如肿胀、发红和皮疹,在女性受试者中也有较高的报告。除此之外,中度和重度全身不良反应以及轻度至中度恶心的发生率在女性中也更为常见。在心肺不良反应方面,所有报告的不良反应在女性中更为常见。总之,COVID-19疫苗产生的不良反应有限,其中大多数报告发生在女性中。这可能与荷尔蒙和心理因素有关。
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引用次数: 12
Pharmacist-led medication reconciliation on admission to an acute psychiatric hospital unit. 急症精神病医院住院时药剂师主导的药物调解。
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-03-14 DOI: 10.18549/PharmPract.2022.2.2650
Joelizy Oliveira, Thaís Costa E Silva, Ana C Cabral, Marta Lavrador, Filipe F Almeida, António Macedo, Carlos Saraiva, Fernando Fernandez-Llimos, M Margarida Caramona, Isabel V Figueiredo, M Margarida Castel-Branco

Background: Therapy management in patients suffering from mental health disorders is complex and the risks derived from changes or interruptions of treatment should not be ignored. Medication reconciliation in psychiatry may reduce medication errors and promote patient safety during transitions of care.

Objective: To identify the influence of complementary information sources in the construction of the best possible medication history, and to ascertain the potential clinical impact of discrepancies identified in a medication reconciliation service.

Methods: An observational study was conducted in an acute mental hospital unit, with a further validation in an internal medicine unit. Adult patients taking at least one medicine admitted in the unit were included. Patients/caregivers were interviewed upon admission and the information gathered was compared with hospital medical and shared electronic medical records. Once the best possible medication history was gathered, therapeutic information was reconciled against the prescription on admission to identify discrepancies. Potential clinical impact of medication errors was classified using the International Safety Classification.

Results: During the study period, 148 patients were admitted, 50.7% females, mean age 54.6 years (SD=16.3). Collaboration of a caregiver was a needed in 74% of the interviews. In total, 1,147 drugs were considered to obtain patients' best possible medication history. After reconciliation, 560 clinically sound intentional discrepancies were identified and 359 discrepancies required further clarification from prescribers: 84.12% "drug omission", 5.57% "drug substitution", 6.96% "dose change", and 3.34% "dosage frequency change". Potential clinical impact of these medication discrepancies was classified as: 95 mild, 100 moderate, and 29 severe medication errors.

Conclusion: About 1 in three intentional discrepancies observed in a pharmacists-led medication reconciliation service required further clarification from prescribers, being 80% of them unintentional discrepancies. Results highlight the importance of the caregiver as source of information for the psychiatric patient, the relevance of analyzing shared electronic health records until 6 months before, and the need to use hospital medical records efficiently. Additionally, 29 discrepancies were classified as errors with potentially severe clinical impact. A medication reconciliation service is concluded to be feasible and necessary in a mental health unit.

背景:精神健康障碍患者的治疗管理是复杂的,改变或中断治疗所带来的风险不容忽视。精神病学的药物调解可以减少药物错误,促进患者在护理过渡期间的安全。目的:确定补充信息源对构建最佳用药史的影响,并确定在药物调节服务中发现的差异对临床的潜在影响。方法:在急性精神病院进行观察性研究,并在内科进行进一步验证。包括至少服用一种药物的成人患者。入院时对患者/护理人员进行访谈,并将收集到的信息与医院医疗和共享电子病历进行比较。一旦收集到最好的用药史,治疗信息与入院时的处方进行核对,以确定差异。用药错误的潜在临床影响采用国际安全分类进行分类。结果:研究期间共收治148例患者,其中女性50.7%,平均年龄54.6岁(SD=16.3)。74%的受访者认为需要护理人员的配合。总共考虑了1147种药物,以获得患者的最佳用药史。经核对,发现560个临床合理的故意差异,其中359个差异需要处方方进一步澄清,其中84.12%为“遗漏用药”,5.57%为“替代用药”,6.96%为“改变剂量”,3.34%为“改变剂量频率”。这些用药差异的潜在临床影响被分类为:轻度用药错误95例,中度用药错误100例,重度用药错误29例。结论:在药师主导的药物调解服务中,约有三分之一的故意差异需要处方者进一步澄清,其中80%为无意差异。结果强调了护理人员作为精神病患者信息来源的重要性,分析6个月前共享的电子健康记录的相关性,以及有效利用医院医疗记录的必要性。此外,29个差异被归类为具有潜在严重临床影响的错误。结论认为,在精神卫生单位开展药物调解服务是可行和必要的。
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引用次数: 1
How is mental health care provided through community pharmacies? A quest for improvement. 如何通过社区药房提供精神卫生保健?对改进的追求。
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-03-11 DOI: 10.18549/PharmPract.2022.2.2648
Catarina Samorinha, Ward Saidawi, Basema Saddik, Abduelmula R Abduelkarem, Karem H Alzoubi, Eman Abu-Gharbieh, Hamzah Alzubaidi

Background: Mental disease burden is increasing globally, and a substantial shortage of mental health professionals remains. Community pharmacists can improve population mental health outcomes to bridge the mental health care gap. However, there is a paucity of data on community pharmacists' provision of mental health care.

Objective: To assess community pharmacist-delivered care to people with mental illness in the United Arab Emirates (UAE), focusing on dispensing and counseling practices, pharmacists' confidence and comfort in providing care, and attitudes and beliefs towards mental illness.

Methods: This was a mixed-methods study with an exploratory, sequential design. Semi-structured interviews explored community pharmacists' practices, challenges and strategies to improve care. Data were analyzed thematically, and the results guided questionnaire development. The questionnaire was also informed by the Framework of Core Mental Health Competencies for All Pharmacy Professionals and other relevant literature and administered to community pharmacists in four out of seven emirates. Logistic regression was used to identify the predictors of pharmacist practices.

Results: In the interviews, community pharmacists described adopting a precautionary attitude and perceived their role as a dispensing one. They reported challenges such as emotional discomfort and lack of training but highlighted the need for a different approach to patients with mental illness. In total, 252 pharmacists completed the questionnaire, and 74% reported performing at least five counseling practices. Logistic regression showed that pharmacists who performed a higher number of practices (≥5) were younger, received continuing education on mental health care in the last two years, and had higher confidence levels.

Conclusion: UAE community pharmacists performed basic dispensing practices and reported discomfort during encounters with patients with mental illness. Training on patient-centered communication skills and psychiatric therapeutics is needed to improve pharmacist-delivered services, alongside increased collaboration with other providers and services.

背景:全球精神疾病负担正在增加,精神卫生专业人员仍然严重短缺。社区药师可以改善人群心理健康状况,弥合心理卫生保健差距。然而,缺乏关于社区药剂师提供精神卫生保健的数据。目的:评估阿拉伯联合酋长国(UAE)社区药剂师为精神疾病患者提供的护理,重点关注配药和咨询实践、药剂师提供护理的信心和舒适度以及对精神疾病的态度和信念。方法:本研究采用探索性、顺序设计的混合方法。半结构化访谈探讨了社区药剂师的做法、挑战和改善护理的策略。对数据进行主题分析,结果指导问卷的编制。调查问卷还参考了《所有药学专业人员核心心理健康能力框架》和其他相关文献,并向七个酋长国中四个酋长国的社区药剂师发放。采用Logistic回归分析确定药师执业的预测因素。结果:在访谈中,社区药剂师描述采取预防态度,并认为他们的角色是一个配药。他们报告了诸如情绪不适和缺乏训练等挑战,但强调需要对精神疾病患者采取不同的方法。总共有252名药剂师完成了问卷调查,74%的药剂师报告至少进行了5次咨询实践。Logistic回归分析结果显示,执业次数(≥5次)较多的药师年龄较小,近两年接受过精神卫生保健继续教育,且置信度较高。结论:阿联酋社区药剂师执行基本的配药操作,并报告在遇到精神疾病患者时感到不适。需要培训以病人为中心的沟通技巧和精神治疗方法,以改善药剂师提供的服务,同时加强与其他提供者和服务机构的合作。
{"title":"How is mental health care provided through community pharmacies? A quest for improvement.","authors":"Catarina Samorinha,&nbsp;Ward Saidawi,&nbsp;Basema Saddik,&nbsp;Abduelmula R Abduelkarem,&nbsp;Karem H Alzoubi,&nbsp;Eman Abu-Gharbieh,&nbsp;Hamzah Alzubaidi","doi":"10.18549/PharmPract.2022.2.2648","DOIUrl":"https://doi.org/10.18549/PharmPract.2022.2.2648","url":null,"abstract":"<p><strong>Background: </strong>Mental disease burden is increasing globally, and a substantial shortage of mental health professionals remains. Community pharmacists can improve population mental health outcomes to bridge the mental health care gap. However, there is a paucity of data on community pharmacists' provision of mental health care.</p><p><strong>Objective: </strong>To assess community pharmacist-delivered care to people with mental illness in the United Arab Emirates (UAE), focusing on dispensing and counseling practices, pharmacists' confidence and comfort in providing care, and attitudes and beliefs towards mental illness.</p><p><strong>Methods: </strong>This was a mixed-methods study with an exploratory, sequential design. Semi-structured interviews explored community pharmacists' practices, challenges and strategies to improve care. Data were analyzed thematically, and the results guided questionnaire development. The questionnaire was also informed by the Framework of Core Mental Health Competencies for All Pharmacy Professionals and other relevant literature and administered to community pharmacists in four out of seven emirates. Logistic regression was used to identify the predictors of pharmacist practices.</p><p><strong>Results: </strong>In the interviews, community pharmacists described adopting a precautionary attitude and perceived their role as a dispensing one. They reported challenges such as emotional discomfort and lack of training but highlighted the need for a different approach to patients with mental illness. In total, 252 pharmacists completed the questionnaire, and 74% reported performing at least five counseling practices. Logistic regression showed that pharmacists who performed a higher number of practices (≥5) were younger, received continuing education on mental health care in the last two years, and had higher confidence levels.</p><p><strong>Conclusion: </strong>UAE community pharmacists performed basic dispensing practices and reported discomfort during encounters with patients with mental illness. Training on patient-centered communication skills and psychiatric therapeutics is needed to improve pharmacist-delivered services, alongside increased collaboration with other providers and services.</p>","PeriodicalId":51762,"journal":{"name":"Pharmacy Practice-Granada","volume":"20 2","pages":"2648"},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/e5/pharmpract-20-2648.PMC9296078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40677278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
What has changed in the pharmaceutical care after COVID-19: Pharmacists' perspective. COVID-19后药学服务发生了什么变化:药剂师的观点。
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-06-01 DOI: 10.18549/PharmPract.2022.2.2656
Zelal Kharaba, Sedq A Moutraji, Rama A Al Khawaldeh, Yassen Alfoteih, Ahmad Z Al Meslamani

Objectives: The study aimed to investigate the impact of Coronavirus disease (COVID-19) on the roles of hospital and community pharmacists in the United Arab Emirates (UAE) and to assess how COVID-19 has affected their roles concerning medication dispensing and review, patient education, and telepharmacy services.

Methods: This was a face-to-face questionnaire-based study. A convenient sampling technique was used to collect responses from 428 licensed community and hospital pharmacists across the UAE. The study tool is a structured questionnaire. Data were cleaned and analysed through SPSS Version 26.

Results: In terms of medication dispensing practice, 314 (73.4%) and 210 (49.1%) of pharmacists reported an increase in the dispensing of over the counter (OTC) medicines and antibiotics after COVID-19, respectively. Of the pharmacists included in the study, 380 (88.8%) and 328 (76.6%) reported an elevation in the engagement in patient education and medication review after COVID-19, respectively. On the other hand, 247 (57.7%) and 179 (41.8%) of pharmacists reported that the frequency of their pharmaceutical interventions and physicians' acceptance of those interventions increased after COVID-19, which was significantly associated (p=0.01) with pharmacists' ability to intervene on the dosage regimen of COVID-19 patient.

Conclusion: Pharmaceutical care in the UAE has evolved after COVID-19, particularly in the aspects of medications dispensing, telepharmacy, and patient-centered services..

目的:本研究旨在调查2019冠状病毒病(COVID-19)对阿拉伯联合酋长国(UAE)医院和社区药剂师角色的影响,并评估2019冠状病毒病(COVID-19)如何影响他们在药物调剂和审查、患者教育和远程药房服务方面的角色。方法:采用面对面问卷调查法。采用方便的抽样技术收集了阿联酋428名有执照的社区和医院药剂师的答复。研究工具是一份结构化问卷。通过SPSS Version 26对数据进行清理和分析。结果:在药品调剂实践方面,314名(73.4%)和210名(49.1%)药师报告新型冠状病毒肺炎后非处方药(OTC)和抗生素的调剂有所增加。在纳入研究的药师中,380名(88.8%)和328名(76.6%)分别报告在新冠肺炎后参与患者教育和药物审查的程度有所提高。另一方面,247名(57.7%)和179名(41.8%)的药师报告在新冠肺炎后其药物干预的频率和医师对这些干预的接受度均有所增加,这与药师干预新冠肺炎患者给药方案的能力显著相关(p=0.01)。结论:2019冠状病毒病后,阿联酋的药学服务得到了发展,特别是在药品调剂、远程药房和以患者为中心的服务方面。
{"title":"What has changed in the pharmaceutical care after COVID-19: Pharmacists' perspective.","authors":"Zelal Kharaba,&nbsp;Sedq A Moutraji,&nbsp;Rama A Al Khawaldeh,&nbsp;Yassen Alfoteih,&nbsp;Ahmad Z Al Meslamani","doi":"10.18549/PharmPract.2022.2.2656","DOIUrl":"https://doi.org/10.18549/PharmPract.2022.2.2656","url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to investigate the impact of Coronavirus disease (COVID-19) on the roles of hospital and community pharmacists in the United Arab Emirates (UAE) and to assess how COVID-19 has affected their roles concerning medication dispensing and review, patient education, and telepharmacy services.</p><p><strong>Methods: </strong>This was a face-to-face questionnaire-based study. A convenient sampling technique was used to collect responses from 428 licensed community and hospital pharmacists across the UAE. The study tool is a structured questionnaire. Data were cleaned and analysed through SPSS Version 26.</p><p><strong>Results: </strong>In terms of medication dispensing practice, 314 (73.4%) and 210 (49.1%) of pharmacists reported an increase in the dispensing of over the counter (OTC) medicines and antibiotics after COVID-19, respectively. Of the pharmacists included in the study, 380 (88.8%) and 328 (76.6%) reported an elevation in the engagement in patient education and medication review after COVID-19, respectively. On the other hand, 247 (57.7%) and 179 (41.8%) of pharmacists reported that the frequency of their pharmaceutical interventions and physicians' acceptance of those interventions increased after COVID-19, which was significantly associated (p=0.01) with pharmacists' ability to intervene on the dosage regimen of COVID-19 patient.</p><p><strong>Conclusion: </strong>Pharmaceutical care in the UAE has evolved after COVID-19, particularly in the aspects of medications dispensing, telepharmacy, and patient-centered services..</p>","PeriodicalId":51762,"journal":{"name":"Pharmacy Practice-Granada","volume":"20 2","pages":"2656"},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/e5/pharmpract-20-2656.PMC9296094.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Guideline-directed medical therapy in heart failure patients with reduced ejection fraction in Oman: utilization, reasons behind non-prescribing, and dose optimization. 阿曼射血分数降低的心力衰竭患者指南指导的药物治疗:使用、不开处方的原因和剂量优化。
IF 2.4 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-04-13 DOI: 10.18549/PharmPract.2022.2.2642
Safiya Al-Aghbari, Juhaina Salim Al-Maqbali, Abdullah M Al Alawi, Mohammed Al Za'abi, Ibrahim Al-Zakwani

Background objective: To determine the reasons behind guideline-directed medical therapy (GDMT) non-prescribing, drug utilization before and after excluding those intolerable to GDMT, as well as dose optimization in heart failure (HF) patients with reduced ejection fraction (<40%) (HFrEF) in Oman.

Methods: The study included HF patients seen at the medical outpatient clinics at Sultan Qaboos University Hospital, Muscat, Oman, between January 2016 and December 2019 and followed up until the end of June 2021. The use of renin-angiotensin-system (RAS) blockers (angiotensin-converting-enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) or angiotensin receptor-neprilysin inhibitors (ARNIs)), beta blockers and mineralocorticoid receptor antagonists (MRAs) were evaluated as per the European, American, and Canadian HF guidelines. Analyses were performed using univariate statistics.

Results: A total of 171 HFrEF patients were enrolled for this study, the overall mean age of the cohort was 63 ± 15 years old and 59% were male. Over 65% of the patients had chronic kidney disease. Almost 55% of the patients were intolerable to GDMT. The proportion of patients on beta blockers, RAS blockers/ hydralazine-isosorbide dinitrate combination, and MRAs, before and after excluding those intolerable to GDMT, were 89%, 97%, and 77%, and, 94%, 47% and 85%, respectively, while the proportion of patients on the GDMT combination concomitantly was 41% and 83%, respectively. A total of 61%, 44% and 100% of the patients were prescribed ≥50% of the target dose for beta blockers, RAS blockers/ HYD-ISDN combination and MRAs respectively, while 19%, 8.2% and 94% of the patients attained 100% of the target dose for beta blockers, RAS blockers/ HYD-ISDN combination and MRAs respectively.

Conclusions: Reasons behind GDMT non-prescribing were frequent and not clearly obvious in patients' medical notes. The majority of the patients were prescribed GDMT. However, dose optimization, specifically for beta blockers and RAS blockers/ HYD-ISDN combination, was still suboptimal. The findings should be interpreted in the context of low study power and that future studies, with larger sample sizes, are warranted to minimize this limitation.

背景目标:确定射血分数降低的心力衰竭(HF)患者未使用指导性医疗疗法(GDMT)的原因、排除不能耐受GDMT的患者前后的药物使用情况以及剂量优化情况(方法:研究纳入2016年1月至2019年12月期间在阿曼马斯喀特苏丹卡布斯大学医院内科门诊就诊的HF患者,随访至2020年6月底:研究对象包括2016年1月至2019年12月期间在阿曼马斯喀特苏丹卡布斯大学医院内科门诊就诊并随访至2021年6月底的高血压患者。根据欧洲、美国和加拿大的高血压指南,对肾素-血管紧张素系统(RAS)阻断剂(血管紧张素转换酶抑制剂(ACEI)或血管紧张素 II 受体阻断剂(ARB)或血管紧张素受体-去甲肾上腺素抑制剂(ARNI))、β受体阻断剂和矿物皮质激素受体拮抗剂(MRA)的使用情况进行了评估。分析采用单变量统计:本研究共招募了 171 名高频低氧血症患者,总平均年龄为 63 ± 15 岁,59% 为男性。超过 65% 的患者患有慢性肾病。近 55% 的患者不能耐受 GDMT。在排除对 GDMT 不耐受的患者之前和之后,使用β受体阻滞剂、RAS 受体阻滞剂/水蛭素-二硝酸异山梨酯复方制剂和 MRA 的患者比例分别为 89%、97% 和 77%,以及 94%、47% 和 85%,而同时使用 GDMT 复方制剂的患者比例分别为 41% 和 83%。分别有61%、44%和100%的患者服用β受体阻滞剂、RAS受体阻滞剂/HYD-ISDN复方制剂和MRA的剂量≥目标剂量的50%,而分别有19%、8.2%和94%的患者服用β受体阻滞剂、RAS受体阻滞剂/HYD-ISDN复方制剂和MRA的剂量达到目标剂量的100%:未开具 GDMT 处方的原因很多,而且在患者的医疗记录中并不明显。大多数患者获得了 GDMT 处方。然而,剂量优化,尤其是β受体阻滞剂和RAS受体阻滞剂/HYD-ISDN联合用药的剂量优化仍不理想。在解释研究结果时,应考虑到研究功率较低的情况,而且未来的研究需要更大的样本量,以尽量减少这一局限性。
{"title":"Guideline-directed medical therapy in heart failure patients with reduced ejection fraction in Oman: utilization, reasons behind non-prescribing, and dose optimization.","authors":"Safiya Al-Aghbari, Juhaina Salim Al-Maqbali, Abdullah M Al Alawi, Mohammed Al Za'abi, Ibrahim Al-Zakwani","doi":"10.18549/PharmPract.2022.2.2642","DOIUrl":"10.18549/PharmPract.2022.2.2642","url":null,"abstract":"<p><strong>Background objective: </strong>To determine the reasons behind guideline-directed medical therapy (GDMT) non-prescribing, drug utilization before and after excluding those intolerable to GDMT, as well as dose optimization in heart failure (HF) patients with reduced ejection fraction (<40%) (HFrEF) in Oman.</p><p><strong>Methods: </strong>The study included HF patients seen at the medical outpatient clinics at Sultan Qaboos University Hospital, Muscat, Oman, between January 2016 and December 2019 and followed up until the end of June 2021. The use of renin-angiotensin-system (RAS) blockers (angiotensin-converting-enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) or angiotensin receptor-neprilysin inhibitors (ARNIs)), beta blockers and mineralocorticoid receptor antagonists (MRAs) were evaluated as per the European, American, and Canadian HF guidelines. Analyses were performed using univariate statistics.</p><p><strong>Results: </strong>A total of 171 HFrEF patients were enrolled for this study, the overall mean age of the cohort was 63 ± 15 years old and 59% were male. Over 65% of the patients had chronic kidney disease. Almost 55% of the patients were intolerable to GDMT. The proportion of patients on beta blockers, RAS blockers/ hydralazine-isosorbide dinitrate combination, and MRAs, before and after excluding those intolerable to GDMT, were 89%, 97%, and 77%, and, 94%, 47% and 85%, respectively, while the proportion of patients on the GDMT combination concomitantly was 41% and 83%, respectively. A total of 61%, 44% and 100% of the patients were prescribed ≥50% of the target dose for beta blockers, RAS blockers/ HYD-ISDN combination and MRAs respectively, while 19%, 8.2% and 94% of the patients attained 100% of the target dose for beta blockers, RAS blockers/ HYD-ISDN combination and MRAs respectively.</p><p><strong>Conclusions: </strong>Reasons behind GDMT non-prescribing were frequent and not clearly obvious in patients' medical notes. The majority of the patients were prescribed GDMT. However, dose optimization, specifically for beta blockers and RAS blockers/ HYD-ISDN combination, was still suboptimal. The findings should be interpreted in the context of low study power and that future studies, with larger sample sizes, are warranted to minimize this limitation.</p>","PeriodicalId":51762,"journal":{"name":"Pharmacy Practice-Granada","volume":"20 2","pages":"2642"},"PeriodicalIF":2.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/83/pharmpract-20-2642.PMC9296089.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The rise of telepharmacy services during the COVID-19 pandemic: A comprehensive assessment of services in the United Arab Emirates. COVID-19大流行期间远程药房服务的兴起:对阿拉伯联合酋长国服务的综合评估
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 DOI: 10.18549/PharmPract.2022.2.2634
Feras Jirjees, Mohanad Odeh, Lynn Aloum, Zelal Kharaba, Karem H Alzoubi, Hala J Al-Obaidi

Objective: The study aimed to explore changes in community pharmacies' processes in response to the pandemic in the United Arab Emirates (UAE) and factors affecting the adoption of these changes.

Method: A cross-sectional study was conducted using a self-administered questionnaire that was distributed to licensed community pharmacists in the UAE. The survey used to collect information on the type of telepharmacy services and related topics such as constraints and supports. The evaluation of services was done for three periods: before, during and after lockdown.

Results: The number of completed surveys was 391. The majority of the participants were under 35 years old (79.5%), female (65.0%), with a bachelor's degree (82.6%), and working in a pharmacy group (70.6%). Pharmacies provided the services by phone (95.6%) and/or messaging applications (80.0%) such as WhatsApp and Messenger. The community pharmacies provided a variety of services using telepharmacy tools such as managing of mild diseases, dispensing and delivering prescribed and OTC medications, general health information, and services for patients with chronic disease. The main factors that had significant effects on several telepharmacy services were pharmacies' type (group/chain vs. individual) and the number of pharmacists in the pharmacy (p < 0.05). Lack of time, training and financial support were the main barriers associated with telepharmacy services among individual pharmacies.

Conclusion: Telepharmacy supported the work of community pharmacies during the COVID-19 pandemic by facilitating the provision of pharmaceutical services. Although the occurrence of several financial and technical problems, it appeared less frequently in pharmacy chains with a large number of pharmacists.

目的:本研究旨在探讨阿拉伯联合酋长国(阿联酋)社区药房应对大流行过程中的变化以及影响采用这些变化的因素。方法:采用一份自我管理的问卷进行横断面研究,该问卷分发给阿联酋有执照的社区药剂师。该调查用于收集远程药房服务类型和相关主题(如限制和支持)的信息。服务评估分三个阶段进行:封锁之前、期间和之后。结果:共完成问卷调查391份。大多数参与者年龄在35岁以下(79.5%),女性(65.0%),拥有学士学位(82.6%),在药房工作(70.6%)。药店通过电话(95.6%)和/或WhatsApp和Messenger等即时通讯应用程序(80.0%)提供服务。社区药房利用远程药房工具提供各种服务,如管理轻度疾病、配发和提供处方药和非处方药、一般健康信息以及为慢性病患者提供服务。影响远程药房服务的主要因素是药房类型(集团/连锁vs个人)和药房药师人数(p < 0.05)。缺乏时间、培训和财政支持是个别药房开展远程药房服务的主要障碍。结论:远程药房通过便利药学服务的提供,支持了社区药房在2019冠状病毒病疫情期间的工作。虽然出现了一些财务和技术问题,但在药剂师人数较多的连锁药店中出现的频率较低。
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引用次数: 8
What do persons with diabetes want from community pharmacies? A qualitative study. 糖尿病患者希望从社区药房得到什么?一项定性研究。
IF 2.4 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-04-01 Epub Date: 2022-06-17 DOI: 10.18549/PharmPract.2022.2.2677
Gitte Reventlov Husted, Rikke Nørgaard Hansen, Mira El-Souri, Janne Kunchel Lorenzen, Peter Bindslev Iversen, Charlotte Verner Rossing

Background: Diabetes is a demanding disease with a complex treatment regimen. Many persons with diabetes have difficulty managing their disease and taking medication as prescribed, possibly because they lack knowledge and sometimes misinterpret medical benefits. Community pharmacies continuously provide professional counselling to persons with diabetes.

Objective: This study aimed to explore 1) which services adults with type 1 and type 2 diabetes want from community pharmacies and 2) how pharmacies can meet these wishes.

Methods: A qualitative, explorative study design using focus group interviews was chosen. Informants were recruited from Region Zealand in Denmark. Data were digitally recorded, transcribed verbatim and analyzed by means of thematic analysis.

Results: Thirteen adults (11 female) with the mean age of 66.2 years (range 49-81 years) participated in one physical (n=6) or one online (n=7) focus group interview. Ten had type 2 diabetes, three had type 1 diabetes. The average duration of participants' diabetes was 13.4 years (range 2.3-33.0 years). The analysis revealed three overall themes of the functions which the informants would like community pharmacies to fulfil: 1) raise awareness of pharmacies' counselling service and competences; 2) act as a dialogue partner; 3) be a source of information and guidance about local activities and support.

Conclusion: The informants did not regard community pharmacies as a natural part of the healthcare system or as a place where they would expect counselling. They would like the community pharmacy to make their medical competences and services obvious and the community pharmacy staff to act as a dialogue partner and provide competent counselling. The informants would like to have a contact person with diabetes competences with whom they can book an appointment to complement over-the-counter counselling. They experience a gap in their care between routine visits in the healthcare system and suggest that community pharmacies counselling services become a natural supplement and that healthcare professionals in the primary and secondary sectors inform patients about the services - especially for patients newly diagnosed with diabetes. Finally, they would like a formal collaboration between diabetes associations and community pharmacies to make their competences, services and information visible.

背景:糖尿病是一种治疗方案复杂的疾病。许多糖尿病患者在控制病情和遵医嘱服药方面存在困难,这可能是因为他们缺乏相关知识,有时还会误解药物的益处。社区药房持续为糖尿病患者提供专业咨询:本研究旨在探讨:1)1 型和 2 型糖尿病成人患者希望社区药房提供哪些服务;2)药房如何满足这些愿望:采用焦点小组访谈的定性探索性研究设计。受访者来自丹麦的新西兰地区。对数据进行数字记录、逐字转录,并通过主题分析法进行分析:13 名平均年龄为 66.2 岁(49-81 岁不等)的成年人(11 名女性)参加了一次实体访谈(6 人)或一次在线焦点小组访谈(7 人)。其中 10 人患有 2 型糖尿病,3 人患有 1 型糖尿病。参与者的平均糖尿病病程为 13.4 年(2.3-33.0 年不等)。分析显示,信息提供者希望社区药房履行的职能有三个总体主题:1) 提高人们对药房咨询服务和能力的认识;2) 充当对话伙伴;3) 提供有关当地活动和支持的信息和指导:结论:受访者并不认为社区药房是医疗保健系统的自然组成部分,也不认为社区药房是他们 希望获得咨询服务的地方。他们希望社区药房将其医疗能力和服务公之于众,希望社区药房的工作人员成为对话伙伴并提供称职的咨询。信息提供者希望能有一个具备糖尿病专业能力的联系人,他们可以与之预约,以补充非处方咨询。他们认为,在医疗系统的例行就诊之间,他们的护理工作存在差距,因此建议社区药房的咨询服务成为一种自然的补充,并建议初级和二级部门的医疗保健专业人员向患者介绍这些服务,尤其是对新诊断出患有糖尿病的患者。最后,他们希望糖尿病协会与社区药房开展正式合作,使社区药房的能力、服务和信息更加明显。
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引用次数: 0
Factors hindering the implementation of clinical pharmacy practice in Egyptian hospitals 阻碍埃及医院实施临床药学实践的因素
IF 2.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2022-03-07 DOI: 10.18549/PharmPract.2022.1.2607
Mohamed Kamal Eldin, Marwan Mohyeldin, Gehad Amgad Zaytoun, Mahmoud Abo Elmaaty, Mahmoud Hamza, S. Fikry, S. Kamal, A. Khalifa, S. Abouelnaga
Background: The direction toward incorporating clinical pharmacy services is increasing worldwide but there are many barriers that hinder its implementation in many countries. The types of barriers vary among countries according to their culture, population, education & economic status. Objective: This study aims to investigate factors hindering the implementation of clinical pharmacy practice in Egyptian hospitals. Methods: Hundred hospital pharmacists working in various reputable hospitals in Egypt participated in a descriptive cross-sectional survey designed as a questionnaire representing the main factors previously reported in the literature to hinder clinical pharmacy implementation in different countries around the world. Cronbach alpha was calculated to test the reliability of the questionnaire. Likert plot was used to graphically present the participants’ responses. Results: The most significant factors that participants reported to hinder the implementation of clinical pharmacy practice in Egyptian hospitals were the lack of clear career path, financial resources, and leadership support. The percentage of participants who agreed that such factors were key players in hindering the implementation of clinical pharmacy practice was 76%, 74%, and 57% respectively. Conclusion: A number of factors were found to impede clinical pharmacy implementation in Egyptian hospitals. Taking corrective measures to resolve such hindrances should ensure proper hospital pharmacy practice and should positively reflect on patient healthcare services provided at the national level.
背景:在世界范围内,整合临床药学服务的方向正在增加,但在许多国家,阻碍其实施的障碍很多。障碍的类型因各国的文化、人口、教育和经济状况而异。目的:探讨埃及医院临床药学实践实施的阻碍因素。方法:在埃及各知名医院工作的100名医院药剂师参加了一项描述性横断面调查,该调查设计为问卷,代表了文献中先前报道的阻碍世界不同国家临床药学实施的主要因素。计算Cronbach alpha来检验问卷的信度。李克特图被用来图形化地呈现参与者的反应。结果:参与者报告阻碍埃及医院实施临床药学实践的最重要因素是缺乏明确的职业道路,财政资源和领导支持。认为这些因素是阻碍临床药学实践实施的关键因素的受访者比例分别为76%、74%和57%。结论:在埃及医院发现了一些阻碍临床药学实施的因素。采取纠正措施解决这些障碍应确保医院药房的适当做法,并应积极反映在国家一级提供的患者保健服务上。
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引用次数: 2
期刊
Pharmacy Practice-Granada
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