Pub Date : 2024-09-01Epub Date: 2024-08-27DOI: 10.1097/01.NPR.0000000000000228
{"title":"School refusal: Considerations for the primary care NP.","authors":"","doi":"10.1097/01.NPR.0000000000000228","DOIUrl":"10.1097/01.NPR.0000000000000228","url":null,"abstract":"","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000216
Evan S Drake, Adriane B Marino, Jenna D Theroux, Kaitlin Roberts
Abstract: In the last decade, the glucagon-like peptide-1 (GLP-1) receptor agonist (RA) drug class has revolutionized treatment for type 2 diabetes mellitus and some of its comorbidities, including obesity and cardiovascular disease. Continued advancements in the GLP-1 RA space show clinical promise for patients, though challenges-including barriers to care such as drug expense and availability-exist. This article provides an overview of available GLP-1 RAs and their mechanisms of action, indications, adverse reactions, and risks, providing practical pearls for providers along the way.
摘要：在过去十年中，胰高血糖素样肽-1（GLP-1）受体激动剂（RA）类药物彻底改变了 2 型糖尿病及其一些合并症（包括肥胖症和心血管疾病）的治疗方法。GLP-1 RA 领域的不断进步为患者带来了临床希望，但同时也存在着挑战，包括药物费用和可用性等治疗障碍。本文概述了现有的 GLP-1 RA 及其作用机制、适应症、不良反应和风险，并为医疗服务提供者提供了实用的指南。
{"title":"GLP-1 RAs: The newest powerhouse in metabolic medicine.","authors":"Evan S Drake, Adriane B Marino, Jenna D Theroux, Kaitlin Roberts","doi":"10.1097/01.NPR.0000000000000216","DOIUrl":"10.1097/01.NPR.0000000000000216","url":null,"abstract":"<p><strong>Abstract: </strong>In the last decade, the glucagon-like peptide-1 (GLP-1) receptor agonist (RA) drug class has revolutionized treatment for type 2 diabetes mellitus and some of its comorbidities, including obesity and cardiovascular disease. Continued advancements in the GLP-1 RA space show clinical promise for patients, though challenges-including barriers to care such as drug expense and availability-exist. This article provides an overview of available GLP-1 RAs and their mechanisms of action, indications, adverse reactions, and risks, providing practical pearls for providers along the way.</p>","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000214
Jamesetta A Newland
{"title":"Public health in the US: Not quite universal coverage.","authors":"Jamesetta A Newland","doi":"10.1097/01.NPR.0000000000000214","DOIUrl":"10.1097/01.NPR.0000000000000214","url":null,"abstract":"","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000211
Madison McKnight, Ikenna Nnamani, Krista Volberding, B Tate Cutshall, Drew A Wells
{"title":"Non-ST elevation myocardial ischemia in a patient on modafinil.","authors":"Madison McKnight, Ikenna Nnamani, Krista Volberding, B Tate Cutshall, Drew A Wells","doi":"10.1097/01.NPR.0000000000000211","DOIUrl":"10.1097/01.NPR.0000000000000211","url":null,"abstract":"","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000218
{"title":"Testosterone replacement therapy for hypogonadism: A primer for primary care.","authors":"","doi":"10.1097/01.NPR.0000000000000218","DOIUrl":"10.1097/01.NPR.0000000000000218","url":null,"abstract":"","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000217
{"title":"More than a new name: Updates in the management of Clostridioides difficile infection.","authors":"","doi":"10.1097/01.NPR.0000000000000217","DOIUrl":"10.1097/01.NPR.0000000000000217","url":null,"abstract":"","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000209
Alexander F Wrynn
Abstract: Infections from Clostridioides difficile (often called C. diff) have long presented challenges for both patients and clinicians. Traditionally, C. diff has been considered a nosocomial infection, but in recent years, a noticeable spike in community-acquired cases has occurred. C. diff infection (CDI) testing is often complicated, as various testing options with differing sensitivity and specificity for active infection are available. Also, recent guideline changes have altered the recommended treatment of infection. This article discusses recent changes to both the diagnosis and management of CDI and how they can be applied to everyday NP practice.
{"title":"More than a new name: Updates in the management of Clostridioides difficile infection.","authors":"Alexander F Wrynn","doi":"10.1097/01.NPR.0000000000000209","DOIUrl":"10.1097/01.NPR.0000000000000209","url":null,"abstract":"<p><strong>Abstract: </strong>Infections from Clostridioides difficile (often called C. diff) have long presented challenges for both patients and clinicians. Traditionally, C. diff has been considered a nosocomial infection, but in recent years, a noticeable spike in community-acquired cases has occurred. C. diff infection (CDI) testing is often complicated, as various testing options with differing sensitivity and specificity for active infection are available. Also, recent guideline changes have altered the recommended treatment of infection. This article discusses recent changes to both the diagnosis and management of CDI and how they can be applied to everyday NP practice.</p>","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000188
Debra A Scrandis, Kayla S Scrandis
Abstract: Perinatal depression (PND) and perinatal anxiety are common conditions that can arise during or after pregnancy and can have a major impact on patients and their families. A potential outcome of PND includes death by suicide, a leading cause of maternal mortality. This article provides an overview of these conditions, including discussion of neurobiology, risk factors, warning signs for individuals at risk for suicide and/or infant harm, and relevant screening tools. Considerations for psychotherapy and pharmacotherapy are highlighted, and an overview of neuroactive steroid gamma-aminobutyric acid A receptor positive allosteric modulators, a newer pharmacologic treatment option for postpartum depression, is provided.
摘要：围产期抑郁症（PND）和围产期焦虑症是妊娠期间或之后可能出现的常见疾病，会对患者及其家庭产生重大影响。围产期抑郁症的潜在后果包括自杀死亡，这是孕产妇死亡的一个主要原因。本文概述了这些病症，包括对神经生物学、风险因素、有自杀和/或伤害婴儿风险的个体的警示信号以及相关筛查工具的讨论。文章强调了心理治疗和药物治疗的注意事项，并概述了神经活性类固醇γ-氨基丁酸 A 受体正异位调节剂，这是治疗产后抑郁症的一种较新的药物疗法。
{"title":"Perinatal depression and anxiety.","authors":"Debra A Scrandis, Kayla S Scrandis","doi":"10.1097/01.NPR.0000000000000188","DOIUrl":"10.1097/01.NPR.0000000000000188","url":null,"abstract":"<p><strong>Abstract: </strong>Perinatal depression (PND) and perinatal anxiety are common conditions that can arise during or after pregnancy and can have a major impact on patients and their families. A potential outcome of PND includes death by suicide, a leading cause of maternal mortality. This article provides an overview of these conditions, including discussion of neurobiology, risk factors, warning signs for individuals at risk for suicide and/or infant harm, and relevant screening tools. Considerations for psychotherapy and pharmacotherapy are highlighted, and an overview of neuroactive steroid gamma-aminobutyric acid A receptor positive allosteric modulators, a newer pharmacologic treatment option for postpartum depression, is provided.</p>","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-25DOI: 10.1097/01.NPR.0000000000000210
Julian L Gallegos
Abstract: Testosterone replacement therapy (TRT) is a crucial intervention for men diagnosed with hypogonadism, a condition characterized by inadequate testosterone production. As primary care NPs play an essential role in managing patients with hypogonadism, they must comprehensively understand TRT. This article serves as a primer for primary care NPs, based on current guidelines, to provide evidence-based care for men with hypogonadism. It offers an overview of the etiology, clinical presentation, diagnostic criteria, and treatment options for hypogonadism, focusing on using TRT appropriately in primary care settings.
{"title":"Testosterone replacement therapy for hypogonadism: A primer for primary care.","authors":"Julian L Gallegos","doi":"10.1097/01.NPR.0000000000000210","DOIUrl":"10.1097/01.NPR.0000000000000210","url":null,"abstract":"<p><strong>Abstract: </strong>Testosterone replacement therapy (TRT) is a crucial intervention for men diagnosed with hypogonadism, a condition characterized by inadequate testosterone production. As primary care NPs play an essential role in managing patients with hypogonadism, they must comprehensively understand TRT. This article serves as a primer for primary care NPs, based on current guidelines, to provide evidence-based care for men with hypogonadism. It offers an overview of the etiology, clinical presentation, diagnostic criteria, and treatment options for hypogonadism, focusing on using TRT appropriately in primary care settings.</p>","PeriodicalId":51812,"journal":{"name":"NURSE PRACTITIONER","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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