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DMAIC-v2: A Novel Guide to the Improvement of Industrial Processes DMAIC-v2:改进工业流程的新指南
IF 1 Q3 Engineering Pub Date : 2024-04-17 DOI: 10.1520/ssms20220037
Jean Bosco Nsekuye, Othmane Erramli, Abdelmajid Elouadi, D. Gretete, Bernard Mushirabwoba
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引用次数: 0
Identification and Interpretation of Melt Pool Shapes in Laser Powder Bed Fusion with Machine Learning 利用机器学习识别和解释激光粉末床融合中的熔池形状
IF 1 Q3 Engineering Pub Date : 2024-04-10 DOI: 10.1520/ssms20230035
Matthew M. Sato, V. W. H. Wong, Ho Yeung, Paul Witherell, K. Law
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引用次数: 0
Study on the deformation capacity of multi-material 4D-printed LCE actuators 多材料3d打印LCE执行器的变形能力研究
Q3 Engineering Pub Date : 2023-11-09 DOI: 10.1142/s273754982240004x
Yutang Tong, Xingzhi Xiao, Tingting Liu, Nan Wang, Wenhe Liao
Liquid crystal elastomers (LCEs) have attracted much attention because of their large, reversible, and anisotropic deformation, fast response to various external stimuli and excellent mechanical properties. LCE ink was prepared by a catalyst-free aza-Michael addition chemistry. A multi-material four-dimensional (4D)-printed laminated LCE actuator including Polydimethylsiloxane (PDMS), conductive circuits and LCEs was fabricated by direct ink writing (DIW) technology. The influence of the input current and resistance values on the thermal effect of conductive circuits was studied. The functional relationship between the LCE actuator’s bending angle and printing parameters was obtained. The LCE actuator with a bending angle controllable at 0–410[Formula: see text] was fabricated. This research is expected to bring about new possibilities in novel intelligent LCE devices with programmable stimuli-responsive properties and optimal actuation capacities.
液晶弹性体(lcd elastomer, LCEs)以其大的、可逆的、各向异性的变形、对各种外界刺激的快速响应和优异的力学性能而受到人们的广泛关注。采用无催化剂的aza-Michael加成化学法制备了LCE油墨。采用直接墨水书写(DIW)技术制备了由聚二甲基硅氧烷(PDMS)、导电电路和LCE组成的多材料四维(4D)印刷层压LCE执行器。研究了输入电流和电阻值对导电电路热效应的影响。得到了LCE执行器的弯曲角度与打印参数之间的函数关系。制作了弯曲角度在0-410可控的LCE作动器[公式:见文]。这项研究有望为具有可编程刺激响应特性和最佳驱动能力的新型智能LCE设备带来新的可能性。
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引用次数: 0
Effect of laser energy density on transformation behavior and mechanical property of NiTi alloys fabricated by laser powder bed fusion 激光能量密度对激光粉末床熔合制备NiTi合金相变行为和力学性能的影响
Q3 Engineering Pub Date : 2023-10-13 DOI: 10.1142/s2737549822400051
Xiaoqiang Wang, Yakun Tao, Shifeng Wen, Yan Zhou, Yusheng Shi
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引用次数: 0
Smart Manufacturing Implementation of a Continuous Downstream Precipitation and Filtration Process for Antibody Purification 智能制造实现抗体纯化的连续下游沉淀和过滤过程
Q3 Engineering Pub Date : 2023-10-06 DOI: 10.1520/ssms20230003
Sambit Ghosh, Matthew Mergy, Mirko Minervini, Jacinta Okpanum, Steven M. Cramer, B. Wayne Bequette, Andrew L. Zydney, Todd M. Przybycien
Recently, continuous bioprocessing has gained momentum in biomanufacturing and can alleviate many of the hurdles faced in batch or semi-batch operations. Moreover, the parallel development of smart manufacturing (SM) allows the rapid small-scale prototyping and large-scale implementation of continuous bioprocesses. With this background, this paper presents the laboratory-scale implementation of a continuous precipitation-filtration process that can ultimately be used for therapeutic protein capture purification. The experimental setup includes four static mixers, four peristaltic pumps, one hollow fiber dewatering filtration module, and multiple pressure sensors and weigh scales. The system also includes an in-line advanced microscopic particle imaging probe that provides real-time images and derived metrics of the precipitate particle morphologies and a fiber optic 880 nm optical absorbance probe. A polyclonal human serum antibody mixture (hIgG) (10 g/L) was used as a stand-in for a monoclonal antibody therapeutic along with 7 % w/v polyethylene glycol (PEG, volume exclusion agent) and 10 mM zinc chloride (cross-linking agent) as the precipitants to demonstrate the principles of operation and control of a precipitation-based process using SM technology. An integrated input/output (I/O) system was used to acquire pressure, flow rate, and weigh scale data and also to communicate with the pumps to change flow rates in real-time. Edge computers communicate with the I/O system and the imaging probe and host the software layer. The software layer enables real-time data acquisition, data-driven and first-principles model predictions, closed-loop control of precipitate particle morphology using pump flow rate of PEG, and cloud communications with the Clean Energy Smart Manufacturing Innovation Institute Smart Manufacturing Innovation Platform. The paper presents the initial results obtained with this integrated system, demonstrating the potential of SM strategies to enhance the production of life-saving biopharmaceutical products.
最近,连续生物加工在生物制造中获得了动力,可以减轻批量或半批量操作中面临的许多障碍。此外,智能制造(SM)的并行发展允许快速的小规模原型和连续生物过程的大规模实施。在此背景下,本文介绍了实验室规模的连续沉淀过滤过程的实现,该过程最终可用于治疗性蛋白质捕获纯化。实验装置包括4台静态混合器、4台蠕动泵、1个中空纤维脱水过滤模块、多个压力传感器和称重秤。该系统还包括一个在线先进的微观颗粒成像探针,提供实时图像和沉淀物颗粒形态的衍生指标,以及一个光纤880 nm光学吸收探针。使用多克隆人血清抗体混合物(hIgG) (10 g/L)作为单克隆抗体治疗的替代品,同时使用7% w/v聚乙二醇(PEG,体积排除剂)和10 mM氯化锌(交联剂)作为沉淀剂,以演示使用SM技术沉淀过程的操作和控制原理。集成的输入/输出(I/O)系统用于获取压力、流量和称重数据,并与泵通信以实时改变流量。边缘计算机与I/O系统和成像探头通信,并托管软件层。软件层可以实现实时数据采集、数据驱动和第一性原理模型预测、利用PEG泵流量对沉淀颗粒形态进行闭环控制,以及与清洁能源智能制造创新研究所智能制造创新平台进行云通信。本文介绍了该集成系统获得的初步结果,展示了SM策略在提高救生生物制药产品生产方面的潜力。
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引用次数: 0
Fabrication of thin-walled hat-shaped beams from ultrahigh strength steel by laser-assisted robotic roller forming 激光辅助机器人滚轮成形超高强度钢薄壁帽型梁
IF 1 Q3 Engineering Pub Date : 2023-08-25 DOI: 10.1142/s273754982340001x
Yi Liu, J. Qiu, Jin-Cheng Wang, M. Bambach, J. Min
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引用次数: 1
Tailoring the microstructure, martensitic transformation temperature and mechanical properties of 4D printed NiTi alloys 定制4D打印NiTi合金的显微组织、马氏体相变温度和力学性能
IF 1 Q3 Engineering Pub Date : 2023-08-04 DOI: 10.1142/s2737549822400038
Jin-Kab Kang, Rui-di Li, Dan-dan Zheng, Xinyan Liu, Duan Lai, Wenjing Huang, Enquan Liang
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引用次数: 0
Digital Twin–Enabled Machine Learning for Smart Manufacturing 面向智能制造的数字孪生机器学习
IF 1 Q3 Engineering Pub Date : 2023-07-03 DOI: 10.1520/ssms20220035
Sanjay Jain, A. Narayanan
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引用次数: 1
4D printing of PLA/PCL composites with tunable shape memory properties via printing and programming parameters 通过打印和编程参数,4D打印具有可调形状记忆性能的PLA/PCL复合材料
IF 1 Q3 Engineering Pub Date : 2023-06-23 DOI: 10.1142/s2737549823500011
Zhenning Z Liu, Peng Gao, Qian Wu, Zhenguo Wang, Jian‐Ying Li, Kun-Chueng Wang, Guiwei Li, Xueli Zhou, Zhengyi Song, Bingqian Li, Qingping Liu
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引用次数: 0
A Graphical Representation of Sensor Mapping for Machine Tool Fault Monitoring and Prognostics for Smart Manufacturing 面向智能制造的机床故障监测与预测传感器映射的图形化表示
IF 1 Q3 Engineering Pub Date : 2023-06-05 DOI: 10.1520/ssms20220031
Abhishek Hanchate, Parth Sanjaybhai Dave, Ankur Verma, Akash Tiwari, Cyan Subhra Mishra, S. Kumara, Anil Srivastava, Hui Yang, Vijaykrishnan Narayanan, John Sampson, M. Kandemir, K. Lee, Tanna Pugh, A. Jorden, Gautam Natarajan, D. Sagapuram, S. Bukkapatnam
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引用次数: 0
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Smart and Sustainable Manufacturing Systems
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