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The In-hospital Outcome of Ventricular Septal Defect Closure and Predictor of Morbidity and Mortality at Tertiary Level Cardiac Center 三级心脏中心室间隔缺损封堵术的住院疗效及病死率预测指标
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40403
N. Gautam, A. Thakur, Marisha Aryal, Rupak Pradhan, D. Karki, Nishes Basnet, Y. M. Singh, R. Timila
Background and Aims: Factors responsible for complications and outcomes of surgical closure of ventricular septal defect differ between different cardiac centers globally. In this study, we tried to evaluate outcomes and predictors of morbidity and mortality of surgical closure of VSD in a single center.Methods: The retrospective cohort study was conducted in Shahid Gangalal National Heart Centre from 14th April 2018 to 13th April 2020. It included consecutive series of patients undergoing ventricular septal defect closure as a primary surgery  Results: Out of a total 166 patients, males were 100 (60%). Adverse complications occurred on 36 (21%) with mortality of 6 (3.6%). The age ranged from 4 months to 35 years. The weight <10 kgs at the time of operation had significant post-operative prolong ventilation duration (more than 6 hours) with a p value of 0.012; significant prolong ICU stays (>2 days) with a p value of <0.001; significant prolong hospital stay (> 7 days) with a p value of <0.001. The longer CPB time was associated with significantly prolonged ventilation duration (p value 0.001); significant longer ICU stay (p value 0.02). The age <1 year at the time of operation had significant prolonged ICU stay; significantly prolonged hospital stays (p value of 0.033). Severe pulmonary artery hypertension (PAH) and weight up to 10 kgs at the time of operation demonstrated a trend towards association with mortality.Conclusion: Surgical VSD closure can be done with acceptable level of mortality and morbidity in our context.
背景和目的:导致室间隔缺损外科闭合术并发症和结果的因素在全球不同的心脏中心不同。在这项研究中,我们试图在一个中心评估VSD手术闭合的结果和发病率和死亡率的预测因素。方法:回顾性队列研究于2018年4月14日至2020年4月13日在Shahid Gangalal国家心脏中心进行。包括连续一系列接受室间隔缺损封堵术作为主要手术的患者。结果:在总共166名患者中,男性为100人(60%)。不良并发症36例(21%),死亡率6例(3.6%),年龄4个月至35岁。重量2天),p值为7天),其中p值<0.001。CPB时间越长,通气持续时间越长(p值0.001);ICU住院时间明显延长(p值0.02)。手术时年龄<1岁的患者ICU住院时间显著延长;住院时间明显延长(p值0.033)。严重肺动脉高压(PAH)和手术时体重高达10kg显示出与死亡率相关的趋势。结论:在我们的情况下,VSD手术闭合可以在可接受的死亡率和发病率水平下进行。
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引用次数: 0
Total Aortic Arch Replacement: Case Report of the first successful total arch replacement in Nepal and Review of contemporary techniques in arch surgery 全主动脉弓置换术:尼泊尔首例成功的全主动脉弓置换术病例报告及当代主动脉弓外科技术综述
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40411
R. Timala, A. Amatya, Nishes Basnet, Rupak Pradhan, Dikshya Joshi, Marisha Aryal, N. Gautam
Aortic arch replacement is formidable cardiac surgery that is fraught with complications like brain injury, coagulopathy along with high mortality. Over the past several years, various techniques like deep hypothermic circulatory arrest, retrograde cerebral perfusion, and selective antegrade cerebral perfusion along with branched graft techniques have been developed with better early outcomes. We share our experience of successful replacement of ascending and total aortic arch in a 60 years old female, who presented with ascending and aortic arch aneurysm.
主动脉弓置换术是一项艰巨的心脏手术,其并发症包括脑损伤、凝血障碍和高死亡率。在过去的几年里,各种技术,如深低温停循环、逆行脑灌注、选择性顺行脑灌注以及分支移植物技术,都得到了发展,具有更好的早期效果。我们分享了一位60岁女性成功置换升主动脉弓和全主动脉弓的经验,她患有升主动脉弓动脉瘤。
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引用次数: 0
Prognostic value of frontal QRST angle and in hospital outcome in ST- Segment Elevation Myocardial Infarction patients undergoing primary percutaneous coronary angioplasty ST段抬高型心肌梗死患者行原发性经皮冠状动脉成形术时,额部QRST角与住院预后的关系
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40396
Arjun Budhathoki, A. Maskey, R. Malla, S. Rajbhandari, D. Basnet, R. Simkhada, R. Tamrakar, Krishna Chandra Adhikari, Bishal Shrestha, C. R. Sharma, M. Koirala, S. Bhandari, Shipra Shrestha, Bishow Raj Baral
Background and Aims: Frontal QRS-T angle has been previously correlated with long term mortality in ST-segment elevation myocardial infarction patients. This study aimed to investigate the prognostic value of frontal QRS-T angle and in-hospital outcomes in the setting of ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention.Methods: We evaluated 97 consecutive patients presenting to the emergency department of Shahid Gangalal National Heart Centre with chest pain of less than 12 hours duration, who were subsequently diagnosed as ST-segment elevation myocardial infarction in a prospective observational study. The study was conducted from July 2020 to June 2021.The data evaluation included demographics, clinical variables, electrocardiogram, length of hospital stay and in hospital mortality. Patient outcomes were stratified into three groups according to frontal QRS-T angle. The relationship between mortality and frontal QRS-T angle was tested with chi-square test. The p-value across the groups was again tested for inter-group significance.Results: Out of 97 patients 67 (69.07%) were male and 30 (30.92%) were female., The mean age of study population was 55.8±11.8 years. The patients under study were divided into three groups based on the calculation of fQRST angle as Group 1 (0-45°) being 46(47.4%), Group 2(46-90°) being 20(20.6%) and Group 3 (>90°) with 31(32%) cases. Diabetes and Congestive heart failure (CHF) patients were more likely to have increase in frontal QRST angle (P value 0.029, 0.012 respectively). Atrial fibrillation (AF) was higher among patients in group 3(>90° frontal QRST angle) which was statistically significant (0.012). Although the mean length of hospital stay was higher among patients with highest frontal QRST angle, it was statistically insignificant (p Value 0.062) however, the chance of hospital stay durations significantly increases across three groups at a 5% significance level (p-value: 0.018). In hospital mortality increased with increase in frontal QRST angle with 8.7%, 15% and 22.6% in group 1, 2 and 3 respectively however it was statistically insignificant.Conclusion:  Diabetes, CHF and AF patients were more likely to have increase in frontal QRST angle. The chance of hospital stay duration significantly increases with increase in frontal QRST angle Although the in hospital mortality increased with increase in the frontal QRST angle, it was statistically insignificant. A prospective study with larger sample size will help to clarify its association.
背景与目的:前侧QRS-T角度与st段抬高型心肌梗死患者的长期死亡率相关。本研究旨在探讨QRS-T额位角在st段抬高型心肌梗死患者行经皮冠状动脉介入治疗中的预后价值及院内预后。方法:在一项前瞻性观察研究中,我们评估了97例连续出现在Shahid Gangalal国家心脏中心急诊科的胸痛持续时间小于12小时的患者,这些患者随后被诊断为st段抬高型心肌梗死。该研究于2020年7月至2021年6月进行。数据评估包括人口统计学、临床变量、心电图、住院时间和住院死亡率。根据QRS-T正面角度将患者分为三组。死亡率与正面QRS-T角的关系采用卡方检验。各组间p值再次进行组间显著性检验。结果:97例患者中,男性67例(69.07%),女性30例(30.92%)。研究人群的平均年龄为55.8±11.8岁。根据fQRST角度计算将患者分为3组,1组(0 ~ 45°)46例(47.4%),2组(46 ~ 90°)20例(20.6%),3组(>90°)31例(32%)。糖尿病和充血性心力衰竭(CHF)患者更容易出现额部QRST角增高(P值分别为0.029、0.012)。心房颤动(AF)发生率在3组患者中较高(>90°额部QRST角),差异有统计学意义(0.012)。虽然额部QRST角度最大的患者平均住院时间更长,但差异无统计学意义(p值0.062),但三组患者住院时间的机会显著增加,差异有5%的显著性水平(p值:0.018)。住院死亡率随额位QRST角度的增加而增加,1、2、3组分别为8.7%、15%、22.6%,但差异无统计学意义。结论:糖尿病、CHF和AF患者更容易出现额部QRST角增高。住院时间随额位QRST角度的增加而增加,住院死亡率随额位QRST角度的增加而增加,但差异无统计学意义。更大样本量的前瞻性研究将有助于澄清其相关性。
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引用次数: 0
Angiographic Significance of ST Depression in Anterior Leads in Acute Inferior ST Elevation Myocardial Infarction. 急性下ST段抬高型心肌梗死前导联ST段压低的血管造影意义。
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40387
R. Simkhada, B. Khan, S. Kc, Arjun Budhathoki, Krishna Chandra Adhikari, Bishow Raj Baral
Background and aims: Electrocardiogram of acute ST elevation inferior myocardial infarction can show concomitant ST depression in anterior leads. We aimed to see its significance on coronary angiogram.Methods: Cross sectional study conducted in Department of Cardiology of Shahid Gangalal National Heart Centre from March 2021 to June 2021. Total of 64 patients of acute inferior myocardial infarction were included consecutively. Electrocardiogram were analyzed for the presence of ST depression in anterior leads (V1-V6). Coronary angiogram were obtained. Linear regression analysis was applied to see correlations.Results: Thirty-four (53.12%) participants had significant ST depression in anterior leads. Their mean age was 64.53±11.67 years. Twenty-two (64.70%) were male. Out of them, 13 (38.23%) were hypertensive, 9 (26.47%) were smoker and 7 (20.58%) were diabetic. Among 30 (46.88%) participants without ST depression, mean age was 56.73±13.31 years and 21 (70%) were male. Out of them, 11 (36.66%) were hypertensive, 12 (40%) were smoker and 11 (33.66%) were diabetic. Culprit vessel was right coronary artery in 22 (64.70%) of those with ST depression and 22 (73.33%) of those without ST depression. Significant left anterior descending artery lesion was seen in 19 (55.88%) of those with ST depression and 3 (10%) of those without depression. Anterior ST depression showed positive correlation with left anterior descending artery lesion.Conclusion: ST depression in anterior leads in acute inferior myocardial infarction can be due to presence of concomitant left anterior descending coronary artery disease.
背景与目的:急性ST段抬高型下壁心肌梗死心电图可显示前导联ST段压低。我们旨在了解它在冠状动脉造影中的意义。方法:2021年3月至2021年6月在Shahid Gangalal国家心脏中心心内科进行的横断面研究。共有64例急性下壁心肌梗死患者被连续纳入。心电图分析前导联ST段压低的存在(V1-V6)。获得冠状动脉造影照片。应用线性回归分析来观察相关性。结果:34名(53.12%)受试者的前导联ST段明显压低。平均年龄64.53±11.67岁。男性22例(64.70%)。其中高血压13例(38.23%),吸烟者9例(26.47%),糖尿病7例(20.58%)。在30名(46.88%)无ST段压低的参与者中,平均年龄为56.73±13.31岁,21名(70%)为男性。其中高血压11例(36.66%),吸烟者12例(40%),糖尿病11例(33.66%)。在ST段压低的患者中,有22例(64.70%)和无ST段压低者中,有2例(73.33%)为右冠状动脉。ST段压低者19例(55.88%),无压低者3例(10%)可见明显的左前降支病变。前ST段压低与左前降支病变呈正相关。结论:急性下壁心肌梗死前导联ST段压低可能与合并左前降支冠状动脉疾病有关。
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引用次数: 0
Is Two Dimensional Echocardiography sufficient for selection of device for successful transcatheter closure of Patent Ductus Arteriosus in Children? 二维超声心动图是否足以选择经导管成功关闭儿童动脉导管未闭的设备?
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40404
M. Shrestha, U. Shakya, Poonam Sharma, S. Shah, Shilpa Aryal, Amshu Shakya, Shistata Rajbhandari, Vidhata Kc, K. Thapa, C. Adhikari
Background and Aims: Two dimensional transthoracic echocardiography (2DE) is widely used for detecting congenital heart disease and is possible to obtain precise measurement of Patent ductus arteriosus (PDA) for device selection required for transcatheter closure. Primary aim of the study is to determine whether echocardiographic assessment alone can be used for selection of device for transcatheter closure of PDA. Methods: Children with PDA and planned for transcatheter intervention were included in this cross-sectional study of one year. PDA was assessed with 2DE and prediction of device size was made. Results: The results were obtained from 107 children. The median age and weight at intervention were 3.8 years (ranging from 6 months to14 years) and 12 kg (ranging from 3.5 to 60 kg). Type A (Conical) PDA was the commonest PDA morphology accounting for 87.8% and 85% in 2DE and angiography respectively. There was no difference (p < 0.05) in the narrowest diameter at pulmonary end measured by 2DE and angiography, however ampulla diameter and ductal length were statistically different (p = 0.95). The predicted size of device by 2DE was discordant (p < 0.05) to the actual device used in a total study population, however when patients with severe pulmonary hypertension, non-type A and larger PDA (narrowest diameter > 6mm) were excluded, the predicted size of device by 2DE was statistically concordant (p = 0.1) to the actual device used in 89 (83%) patients. Conclusion: Two dimensional Transthoracic echocardiography alone may be helpful in choosing the device during transcatheter closure of PDA in selective group of patients.
背景和目的:二维经胸超声心动图(2DE)被广泛用于检测先天性心脏病,并有可能获得动脉导管未闭(PDA)的精确测量,以选择经导管封堵所需的装置。本研究的主要目的是确定超声心动图评估是否可以单独用于PDA经导管封堵装置的选择。方法:将计划经导管介入治疗的PDA儿童纳入这项为期一年的横断面研究。用2DE评估PDA,并预测设备尺寸。结果:对107名儿童进行了问卷调查。干预时的中位年龄和体重分别为3.8岁(6个月至14岁)和12公斤(3.5至60公斤)。A型(锥形)PDA是最常见的PDA形态,在2DE和血管造影术中分别占87.8%和85%。2DE和血管造影术测量的肺端最窄直径没有差异(p<0.05),但壶腹直径和导管长度有统计学差异(p=0.95)。2DE预测的装置尺寸与整个研究人群中使用的实际装置不一致(p<0.01),然而,当患有严重肺动脉高压的患者,排除了非A型和较大的PDA(最窄直径>6mm),2DE预测的装置尺寸与89名(83%)患者使用的实际装置在统计学上一致(p=0.01)。结论:单纯二维经胸超声心动图在选择性PDA导管封堵术中有助于选择合适的装置。
{"title":"Is Two Dimensional Echocardiography sufficient for selection of device for successful transcatheter closure of Patent Ductus Arteriosus in Children?","authors":"M. Shrestha, U. Shakya, Poonam Sharma, S. Shah, Shilpa Aryal, Amshu Shakya, Shistata Rajbhandari, Vidhata Kc, K. Thapa, C. Adhikari","doi":"10.3126/njh.v18i2.40404","DOIUrl":"https://doi.org/10.3126/njh.v18i2.40404","url":null,"abstract":"Background and Aims: Two dimensional transthoracic echocardiography (2DE) is widely used for detecting congenital heart disease and is possible to obtain precise measurement of Patent ductus arteriosus (PDA) for device selection required for transcatheter closure. Primary aim of the study is to determine whether echocardiographic assessment alone can be used for selection of device for transcatheter closure of PDA. \u0000Methods: Children with PDA and planned for transcatheter intervention were included in this cross-sectional study of one year. PDA was assessed with 2DE and prediction of device size was made. \u0000Results: The results were obtained from 107 children. The median age and weight at intervention were 3.8 years (ranging from 6 months to14 years) and 12 kg (ranging from 3.5 to 60 kg). Type A (Conical) PDA was the commonest PDA morphology accounting for 87.8% and 85% in 2DE and angiography respectively. There was no difference (p < 0.05) in the narrowest diameter at pulmonary end measured by 2DE and angiography, however ampulla diameter and ductal length were statistically different (p = 0.95). The predicted size of device by 2DE was discordant (p < 0.05) to the actual device used in a total study population, however when patients with severe pulmonary hypertension, non-type A and larger PDA (narrowest diameter > 6mm) were excluded, the predicted size of device by 2DE was statistically concordant (p = 0.1) to the actual device used in 89 (83%) patients. \u0000Conclusion: Two dimensional Transthoracic echocardiography alone may be helpful in choosing the device during transcatheter closure of PDA in selective group of patients.","PeriodicalId":52010,"journal":{"name":"Nepalese Heart Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48298431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Agitated Saline Contrast Echocardiogram In Cardio-Pulmonary Evaluation 激动生理盐水对比超声心动图在心肺评价中的应用
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40405
A. Hirachan, Ranjit Sharma, Prabesh Neupane
Agitated saline contrast echocardiogram (ASC) is a very useful technique to detect various intracardiac and extra  cardiac  shunts  in  daily cardiology practice . Conventional 2D and color echocardiogram may not be well effective in ruling out various intracardiac shunts especially with patients having poor echo window.  The introduction of agitated saline with bubbles formed during the study can help delineate different right to left shunt physiology commonly like patent foramen ovale (PFO) which is often sought for in evaluation of cases  with young stroke . Various other etiologies like atrial septal defects, atrial septal aneurysm, large right to left shunts with eisenmengerisation can also be evaluated with this simple bedside study.
在日常心脏病学实践中,搅拌盐水对比超声心动图(ASC)是一种非常有用的技术,可以检测各种心内和心外分流。传统的二维和彩色超声心动图可能无法很好地排除各种心内分流,尤其是对于回声窗较差的患者。在研究过程中引入带有气泡的搅拌盐水可以帮助描述不同的左右分流生理学,通常如卵圆孔未闭(PFO),这在评估年轻中风病例时经常被寻求。通过这项简单的床边研究,还可以评估各种其他病因,如房间隔缺损、房间隔动脉瘤、大的从右到左分流伴能量不足。
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引用次数: 0
Rastelli operation for double outlet right ventricle, pulmonary atresia with ductal dependent pulmonary flow 右心室双出口肺闭锁伴导管依赖肺血流的Rastelli手术
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40406
N. Panthee, S. Pradhan, Raamesh Koirala, Bishow Pokhrel, Deekshya Thapaliya, A. Thakur, U. Jha, R. Timala
Double outlet right ventricle (DORV) with or without pulmonary atresia is a common indication for Rastelli operation. We very infrequently perform this surgery in our center. Here, we report a case of a ten-year-old girl who recently underwent Rastelli operation and patent ductus arteriosus (PDA) ligation for DORV, pulmonary atresia with ductal dependent pulmonary circulation by using custom-made valved conduit
双出口右心室(DORV)伴或不伴肺动脉闭锁是Rastelli手术的常见指征。我们很少在中心做这种手术。在这里,我们报告了一个10岁女孩的病例,她最近接受了Rastelli手术和动脉导管未闭(PDA)结扎术,通过使用定制的带瓣导管治疗DORV,这是一种具有导管依赖性肺循环的肺闭锁
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引用次数: 0
Echocardiography Screening for Diagnosis of Latent RHD Using Nurses: Is the Project Feasible for Nepal? 使用护士进行超声心动图筛查诊断潜在RHD:该项目在尼泊尔可行吗?
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40386
P. Regmi, R. Kafle
Rheumatic Heart Disease (RHD) is a preventable disease which occurs years or decades after the onset of Acute Rheumatic Fever (ARF) in childhood. The prevalence of RHD is still high in Nepal, with most cases of latent RHD concentrated in the rural, resource-limited setting. The sequelae of latent RHD cases often manifest decades later, causing a significant burden on the health system. Training of non-experts with simple protocols in such remote setting for screening of latent RHD is showing promising results worldwide. Screening of latent RHD is advocated in RHD endemic areas where early detection by echo screening can alleviate a massive burden on morbidity and mortality in the future. More research is needed to explore this possibility in the context of an endemic country like Nepal to tackle the burden of RHD.
风湿性心脏病(RHD)是一种可预防的疾病,发生在儿童急性风湿热(ARF)发作数年或数十年后。RHD在尼泊尔的患病率仍然很高,大多数潜在RHD病例集中在资源有限的农村地区。潜在RHD病例的后遗症往往在几十年后显现,给卫生系统造成重大负担。在这样的远程环境中,用简单的协议对非专家进行培训,以筛查潜在的RHD,在世界范围内显示出有希望的结果。在RHD流行地区提倡筛查潜在的RHD,通过回声筛查进行早期检测可以减轻未来发病率和死亡率的巨大负担。需要进行更多的研究,以在尼泊尔这样的地方病流行国家的背景下探索这种可能性,以应对RHD的负担。
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引用次数: 2
Transcatheter Closure of Atrial Septal Defects with 40 mm Septal Occluder in Shahid Gangalal National Heart Centre, Nepal 经导管封堵心房间隔缺损尼泊尔Shahid Gangalal国家心脏中心40mm间隔封堵器
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40427
C. Adhikari, K. Acharya, A. Bogati, A. Acharya, Roshani Shahi, Vijay Ghimire, D. Prajapati
Background and Aims:  Transcatheter closure of Atrial septal defect (ASD) is one of important modality of treatment these days for ASD secundum. However, there is a paucity of data on transcatheter closure of ASDs with ³40 septal occluder. We aim to study the outcome of ASD device closure with  ³40 mm Septal Occluder in Shahid Gangalal National Heart Centre, Nepal. Methods:   It was a prospective single center study conducted at Shahid Gangalal National Heart Centre, Nepal.Among the 27 patient who underwent successful device closure with ³40 mm devices from January 2016 till December 2019, twenty-six patients could be prospectively followed up during May 2020 till December 2020. A Performa was designed to collect information about age, gender, ASD size, ASD device type and size. Right atrium(RA) and right ventricle(RV) dimension, level of tricuspid regurgitation (TR) and tricuspid regurgitation pressure gradient before the procedure and at the time of follow up were also recorded. Results: Amplatzer septal occluder (40mm) was used in 25 (96.1%) patients and Memopart device (42mm) was used in 1 (3.9%) patient.  Before the procedure all patients had dilated RA and RV, Mild TR, moderate TR and severe TR was present in 14 (53.8%), 10 (38.4%) and 2 (7.7%) patients respectively. At follow up, only one (3.9%) patient had dilated RA and RV. Mean Tricuspid regurgitation pressure gradient decreased from mean 44.4 mmHg to 18.9 mmHg. Conclusion: Transcatheter Closure of Atrial Septal Defects with ³40 mm Septal Occluder is safe and effective in short term follow up.
背景与目的:经导管房间隔缺损闭合术是目前治疗继发性房间隔缺损的重要方式之一。然而,关于使用³40间隔闭塞器经导管关闭asd的数据缺乏。我们的目的是研究尼泊尔Shahid Gangalal国家心脏中心使用340mm间隔封堵器关闭ASD装置的结果。方法:这是一项在尼泊尔Shahid Gangalal国家心脏中心进行的前瞻性单中心研究。在2016年1月至2019年12月27例成功闭合³40 mm装置的患者中,有26例患者可在2020年5月至2020年12月进行前瞻性随访。设计了一个Performa来收集年龄、性别、ASD大小、ASD设备类型和大小的信息。记录术前及随访时右心房(RA)、右心室(RV)尺寸、三尖瓣反流水平(TR)及三尖瓣反流压力梯度。结果:25例(96.1%)患者使用Amplatzer (40mm)隔闭塞器,1例(3.9%)患者使用Memopart (42mm)隔闭塞器。术前所有患者均有RA和RV扩张,轻度TR 14例(53.8%),中度TR 10例(38.4%),重度TR 2例(7.7%)。在随访中,只有1例(3.9%)患者出现RA和RV扩张。平均三尖瓣反流压力梯度从平均44.4 mmHg降至18.9 mmHg。结论:340mm房间隔封堵器经导管封堵房间隔缺损短期随访安全有效。
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引用次数: 0
Right Atrial Thrombus Associated with Central Venous Catheter after Surgical Repair of Co-arctation of Aorta 主动脉共缩修复术后伴中心静脉置管的右心房血栓
IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2021-11-23 DOI: 10.3126/njh.v18i2.40409
S. Bajracharya, Sandeep Sapkota
Central venous catheterization (CVC) is a routine and essential procedure performed in patients undergoing cardiac surgery. However, its use is not without complications ranging from mechanical to infectious to thrombotic in nature. Catheter-related right atrial thrombosis (CRAT) is usually underreported as it is commonly small in size and asymptomatic. Nevertheless, CRAT might lead to a potentially severe and life threatening complication in both adult and young patients. Up to 30% of patients with CVCs are estimated to be affected by CRAT.  Anticoagulation and subsequently catheter removal were recommended as a first-line therapy and have suggested that no intervention may be associated with a high mortality rate. Here, we report a case of a 3-months-old male child who underwent coarctation of aorta repair and was diagnosed with right atrial thrombosis associated with CVC in postoperative period and anticoagulated with unfractionated heparin. The thrombus was followed up closely and when there was no further decrease in the size of the mass around 9 days after the diagnosis, the CVC was removed. The heparin was continued even after removal of CVC for further 7 days and patient was eventually discharged from the hospital.
中心静脉导管插入术(CVC)是心脏手术患者进行的一项常规和必要的手术。然而,它的使用并非没有并发症,从机械性到感染性再到血栓性。导管相关右心房血栓形成(CRAT)通常报告不足,因为它通常体积小且无症状。然而,CRAT可能会在成年和年轻患者中导致潜在的严重和危及生命的并发症。据估计,多达30%的CVCs患者受到CRAT的影响。建议将抗凝和随后的导管移除作为一线治疗,并表明没有干预可能与高死亡率相关。在此,我们报告了一例3个月大的男性儿童,他接受了主动脉缩窄修复术,在术后被诊断为右心房血栓形成伴CVC,并用普通肝素抗凝。对血栓进行了密切随访,在诊断后9天左右,当肿块的大小没有进一步减小时,CVC被移除。即使在移除CVC后,肝素仍继续使用7天,患者最终出院。
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引用次数: 0
期刊
Nepalese Heart Journal
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